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This book constitutes the refereed proceedings of the First International Conference on Bioengineering and Biomedical Signal and Image Processing, BIOMESIP 2021, held in Meloneras, Gran Canaria, Spain, in July 2021. The 41 full and 5 short papers were carefully reviewed and selected from 121 submissions. The papers are grouped in topical issues on biomedical applications in molecular, structural, and functional imaging; biomedical computing; biomedical signal measurement, acquisition and processing; computerized medical imaging and graphics; disease control and diagnosis; neuroimaging; pattern recognition and machine learning for biosignal data; personalized medicine; and COVID-19.

This two-volume set LNCS 12861 and LNCS 12862 constitutes the refereed proceedings of the 16th International Work-Conference on Artificial Neural Networks, IWANN 2021, held virtually, in June 2021.The 85 full papers presented in this two-volume set were carefully reviewed and selected from 134 submissions. The papers are organized in topical sections on Deep Learning for Biomedicine, Intelligent Computing Solutions for SARS-CoV-2 Covid-19, Advanced Topics in Computational Intelligence, Biosignals Processing, Neuro-Engineering and much more.

This volume constitutes the proceedings of the 8th International Work-Conference on IWBBIO 2020, held in Granada, Spain, in May 2020. The total of 73papers presented in the proceedings, was carefully reviewed and selected from 241 submissions. The papers are organized in topical sections as follows: Biomarker Identification; Biomedical Engineering; Biomedical Signal Analysis; Bio-Nanotechnology; Computational Approaches for Drug Design and Personalized Medicine; Computational Proteomics and Protein-Protein Interactions; Data Mining from UV/VIS/NIR Imaging and Spectrophotometry; E-Health Technology, Services and Applications; Evolving Towards Digital Twins in Healthcare (EDITH); High Performance in Bioinformatics; High-Throughput Genomics: Bioinformatic Tools and Medical Applications; Machine Learning in Bioinformatics; Medical Image Processing; Simulation and Visualization of Biological Systems.

This two-volume set LNCS 10305 and LNCS 10306 constitutes the refereed proceedings of the 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, held at Gran Canaria, Spain, in June 2019.The 150 revised full papers presented in this two-volume set were carefully reviewed and selected from 210 submissions. The papers are organized in topical sections on machine learning in weather observation and forecasting; computational intelligence methods for time series; human activity recognition; new and future tendencies in brain-computer interface systems; random-weights neural networks; pattern recognition; deep learning and natural language processing; software testing and intelligent systems; data-driven intelligent transportation systems; deep learning models in healthcare and biomedicine; deep learning beyond convolution; artificial neural network for biomedical image processing; machine learning in vision and robotics; system identification, process control,and manufacturing; image and signal processing; soft computing; mathematics for neural networks; internet modeling, communication and networking; expert systems; evolutionary and genetic algorithms; advances in computational intelligence; computational biology and bioinformatics.

This two-volume set LNCS 10305 and LNCS 10306 constitutes the refereed proceedings of the 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, held at Gran Canaria, Spain, in June 2019.The 150 revised full papers presented in this two-volume set were carefully reviewed and selected from 210 submissions. The papers are organized in topical sections on machine learning in weather observation and forecasting; computational intelligence methods for time series; human activity recognition; new and future tendencies in brain-computer interface systems; random-weights neural networks; pattern recognition; deep learning and natural language processing; software testing and intelligent systems; data-driven intelligent transportation systems; deep learning models in healthcare and biomedicine; deep learning beyond convolution; artificial neural network for biomedical image processing; machine learning in vision and robotics; system identification, process control,and manufacturing; image and signal processing; soft computing; mathematics for neural networks; internet modeling, communication and networking; expert systems; evolutionary and genetic algorithms; advances in computational intelligence; computational biology and bioinformatics.

The two-volume set LNBI 11465 and LNBI 11466 constitutes the proceedings of the 7th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2019, held in Granada, Spain, in May 2019. The total of 97 papers presented in the proceedings, was carefully reviewed and selected from 301 submissions. The papers are organized in topical sections as follows: Part I: High-throughput genomics: bioinformatics tools and medical applications; omics data acquisition, processing, and analysis; bioinformatics approaches for analyzing cancer sequencing data; next generation sequencing and sequence analysis; structural bioinformatics and function; telemedicine for smart homes and remote monitoring; clustering and analysis of biological sequences with optimization algorithms; and computational approaches for drug repurposing and personalized medicine. Part II: Bioinformatics for healthcare and diseases; computational genomics/proteomics; computationalsystems for modelling biological processes; biomedical engineering; biomedical image analysis; and biomedicine and e-health.

The two-volume set LNBI 11465 and LNBI 11466 constitutes the proceedings of the 7th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2019, held in Granada, Spain, in May 2019. The total of 97 papers presented in the proceedings, was carefully reviewed and selected from 301 submissions. The papers are organized in topical sections as follows: Part I: High-throughput genomics: bioinformatics tools and medical applications; omics data acquisition, processing, and analysis; bioinformatics approaches for analyzing cancer sequencing data; next generation sequencing and sequence analysis; structural bioinformatics and function; telemedicine for smart homes and remote monitoring; clustering and analysis of biological sequences with optimization algorithms; and computational approaches for drug repurposing and personalized medicine. Part II: Bioinformatics for healthcare and diseases; computational genomics/proteomics; computationalsystems for modelling biological processes; biomedical engineering; biomedical image analysis; and biomedicine and e-health.

This two volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

This two-volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This book constitutes the refereed proceedings of the 4th International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2016, held in Granada, Spain, in April 2016. The 69 papers presented were carefully reviewed and selected from 286 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; biomedical image analysis; biomedical signal analysis; computational systems for modeling biological processes; eHealth; tools for next generation sequencing data analysis; assistive technology for people with neuromotor disorders; fundamentals of biological dynamics and maximization of the information extraction from the experiments in the biological systems; high performance computing in bioinformatics, computational biology and computational chemistry; human behavior monitoring, analysis and understanding; pattern recognition and machine learning in the -omics sciences; and resources for bioinformatics.

This two-volume set LNCS 9094 and LNCS 9095 constitutes the thoroughly refereed proceedings of the 13th International Work-Conference on Artificial Neural Networks, IWANN 2015, held in Palma de Mallorca, Spain, in June 2013. The 99 revised full papers presented together with 1 invited talk were carefully reviewed and selected from 195 submissions. The papers are organized in topical sections on brain-computer interfaces: applications and tele-services; multi-robot systems: applications and theory (MRSAT); video and image processing; transfer learning; structures, algorithms and methods in artificial intelligence; interactive and cognitive environments; mathematical and theoretical methods in fuzzy systems; pattern recognition; embedded intelligent systems; expert systems; advances in computational intelligence; and applications of computational intelligence.

This two-volume set LNCS 9094 and LNCS 9095 constitutes the thoroughly refereed proceedings of the 13th International Work-Conference on Artificial Neural Networks, IWANN 2015, held in Palma de Mallorca, Spain, in June 2013. The 99 revised full papers presented together with 1 invited talk were carefully reviewed and selected from 195 submissions. The papers are organized in topical sections on brain-computer interfaces: applications and tele-services; multi-robot systems: applications and theory (MRSAT); video and image processing; transfer learning; structures, algorithms and methods in artificial intelligence; interactive and cognitive environments; mathematical and theoretical methods in fuzzy systems; pattern recognition; embedded intelligent systems; expert systems; advances in computational intelligence; and applications of computational intelligence.

The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain in April 2015. The 134 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, eHealth, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.

The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain, in April 2015.The 135 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, e Health, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.

This two-volume set LNCS 7902 and 7903 constitutes the refereed proceedings of the 12th International Work-Conference on Artificial Neural Networks, IWANN 2013, held in Puerto de la Cruz, Tenerife, Spain, in June 2013. The 116 revised papers were carefully reviewed and selected from numerous submissions for presentation in two volumes. The papers explore sections on mathematical and theoretical methods in computational intelligence, neurocomputational formulations, learning and adaptation emulation of cognitive functions, bio-inspired systems and neuro-engineering, advanced topics in computational intelligence and applications

This two-volume set LNCS 7902 and 7903 constitutes the refereed proceedings of the 12th International Work-Conference on Artificial Neural Networks, IWANN 2013, held in Puerto de la Cruz, Tenerife, Spain, in June 2013. The 116 revised papers were carefully reviewed and selected from numerous submissions for presentation in two volumes. The papers explore sections on mathematical and theoretical methods in computational intelligence, neurocomputational formulations, learning and adaptation emulation of cognitive functions, bio-inspired systems and neuro-engineering, advanced topics in computational intelligence and applications.

This two-volume set LNCS 6691 and 6692 constitutes the refereed proceedings of the 11th International Work-Conference on Artificial Neural Networks, IWANN 2011, held in Torremolinos-Málaga, Spain, in June 2011. The 154 revised papers were carefully reviewed and selected from 202 submissions for presentation in two volumes. The second volume includes 76 papers organized in topical sections on video and image processing; hybrid artificial neural networks: models, algorithms and data; advances in machine learning for bioinformatics and computational biomedicine; biometric systems for human-machine interaction; data mining in biomedicine; bio-inspired combinatorial optimization; applying evolutionary computation and nature-inspired algorithms to formal methods; recent advances on fuzzy logic and soft computing applications; new advances in theory and applications of ICA-based algorithms; biological and bio-inspired dynamical systems; and interactive and cognitive environments. The last section contains 9 papers from the International Workshop on Intelligent Systems for Context-Based Information Fusion, ISCIF 2011, held at IWANN 2011.

This two-volume set LNCS 6691 and 6692 constitutes the refereed proceedings of the 11th International Work-Conference on Artificial Neural Networks, IWANN 2011, held in Torremolinos-Málaga, Spain, in June 2011. The 154 revised papers were carefully reviewed and selected from 202 submissions for presentation in two volumes. The first volume includes 69 papers organized in topical sections on mathematical and theoretical methods in computational intelligence; learning and adaptation; bio-inspired systems and neuro-engineering; hybrid intelligent systems; applications of computational intelligence; new applications of brain-computer interfaces; optimization algorithms in graphic processing units; computing languages with bio-inspired devices and multi-agent systems; computational intelligence in multimedia processing; and biologically plausible spiking neural processing.