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High Performance Scientific And Engineering Computing: Hardware/Software Support contains selected chapters on hardware/software support for high performance scientific and engineering computing from prestigious workshops in the fields such as PACT-SHPSEC, IPDPS-PDSECA and ICPP-HPSECA. This edited volume is basically divided into six main sections which include invited material from prominent researchers around the world. We believe all of these contributed chapters and topics not only provide novel ideas, new results and state-of-the-art techniques in this field, but also stimulate the future research activities in the area of high performance computing for science and engineering applications. High Performance Scientific And Engineering Computing: Hardware/Software Support is designed for a professional audience, composed of researchers and practitioners in industry. This book is also suitable as a secondary text for graduate-level students in computer science and engineering.

Parallel and distributed computing in the 1980s and 1990s had great in?uence onapplication developmentin science, engineering andbusiness computing. The improvements in computation and communication capabilities have enabled the creation of demanding applications in critical domains such as the environment, health, aerospace, and other areas of science and technology. Similarly, new classesofapplicationsareenabledbytheavailabilityofheterogeneouslarge-scale distributed systems which are becoming available nowadays (based on techno- giessuchasgridandpeer-to-peersystems).Parallelcomputingsystemsexploita large diversity of computer architectures, from supercomputers, shared-memory or distributed-memory multi processors, to local networks and clusters of p- sonal computers. With the recent emergence of multi core architectures, parallel computing is now set to achieve “mainstream” status. Approaches that have been advocated by parallelcomputing researchersin the past are now being utilized in a number of software libraries and hardware systems that are available for everyday use. Parallel computing ideas have also come to dominate areas such as multi user gaming (especially in the development of gaming engines based on “cell” arc- tectures) – often ignored by many “serious” researchers in the past, but which now are set to have a growing user base of tens of millions across the world. In recent years, focus has also shifted to support energy e?ciency in com- tation, with some researchers proposing a new metric of performance based on Flops/Watt.

The 5th Transactions on Computational Systems Biology collects carefully chosen and enhanced contributions initially presented at the 2005 IEEE International Conference on Granular Computing held in Beijing, China, in July 2005. The 9 papers in this special issue cover various aspects of computational methods, algorithms and techniques in bioinformatics such as gene expression analysis, biomedical literature mining and natural language processing, protein structure prediction, biological database management and biomedical information retrieval.

Welcome to the proceedings of GCC2004 and the city of Wuhan. Grid computing has become a mainstream research area in computer science and the GCC conference has become one of the premier forums for presentation of new and exciting research in all aspectsofgridandcooperativecomputing. Theprogramcommitteeispleasedtopresent the proceedings of the 3rd International Conference on Grid and Cooperative Comp- ing (GCC2004), which comprises a collection of excellent technical papers, posters, workshops, and keynote speeches. The papers accepted cover a wide range of exciting topics, including resource grid and service grid, information grid and knowledge grid, grid monitoring,managementand organizationtools, grid portal, grid service, Web s- vices and their QoS, service orchestration, grid middleware and toolkits, software glue technologies, grid security, innovative grid applications, advanced resource reservation andscheduling,performanceevaluationandmodeling,computer-supportedcooperative work, P2P computing, automatic computing, and meta-information management. The conference continues to grow and this year a record total of 581 manuscripts (including workshop submissions) were submitted for consideration. Expecting this growth, the size of the program committee was increased from 50 members for GCC 2003 for 70 in GCC 2004. Relevant differences from previous editions of the conf- ence: it is worth mentioning a signi?cant increase in the number of papers submitted by authors from outside China; and the acceptance rate was much lower than for p- vious GCC conferences. From the 427 papers submitted to the main conference, the program committee selected only 96 regular papers for oral presentation and 62 short papers for poster presentation in the program.

Welcome to the proceedings of GCC2004 and the city of Wuhan. Grid computing has become a mainstream research area in computer science and the GCC conference has become one of the premier forums for presentation of new and exciting research in all aspectsofgridandcooperativecomputing. Theprogramcommitteeispleasedtopresent the proceedings of the 3rd International Conference on Grid and Cooperative Comp- ing (GCC2004), which comprises a collection of excellent technical papers, posters, workshops, and keynote speeches. The papers accepted cover a wide range of exciting topics, including resource grid and service grid, information grid and knowledge grid, grid monitoring,managementand organizationtools, grid portal, grid service, Web s- vices and their QoS, service orchestration, grid middleware and toolkits, software glue technologies, grid security, innovative grid applications, advanced resource reservation andscheduling,performanceevaluationandmodeling,computer-supportedcooperative work, P2P computing, automatic computing, and meta-information management. The conference continues to grow and this year a record total of 581 manuscripts (including workshop submissions) were submitted for consideration. Expecting this growth, the size of the program committee was increased from 50 members for GCC 2003 for 70 in GCC 2004. Relevant differences from previous editions of the conf- ence: it is worth mentioning a signi?cant increase in the number of papers submitted by authors from outside China; and the acceptance rate was much lower than for p- vious GCC conferences. From the 427 papers submitted to the main conference, the program committee selected only 96 regular papers for oral presentation and 62 short papers for poster presentation in the program.