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This book constitutes the proceedings of the 7th International Conference on Future Data and Security Engineering, FDSE 2020, held in Quy Nhon, Vietnam, in November 2020.•The 29 full papers and 8 short were carefully reviewed and selected from 161 submissions. The selected papers are organized into the following topical headings: big data analytics and distributed systems; security and privacy engineering; industry 4.0 and smart city: data analytics and security; data analytics and healthcare systems; machine learning-based big data processing; emerging data management systems and applications; and short papers: security and data engineering. • The conference was held virtually due to the COVID-19 pandemic.