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This textbook provides a concise introduction to optimal experimental design and efficiently prepares the reader for research in the area. It presents the common concepts and techniques for linear and nonlinear models as well as Bayesian optimal designs. The last two chapters are devoted to particular themes of interest, including recent developments and hot topics in optimal experimental design, and real-world applications. Numerous examples and exercises are included, some of them with solutions or hints, as well as references to the existing software for computing designs. The book is primarily intended for graduate students and young researchers in statistics and applied mathematics who are new to the field of optimal experimental design. Given the applications and the way concepts and results are introduced, parts of the text will also appeal to engineers and other applied researchers.

The volume contains the proceedings of the 8th Workshop on Model-Oriented Design and Analysis. This book offers leading and pioneering work on optimal experimental designs, both from a mathematical/statistical point of view and with regard to real applications. Scientists from all over the world, from Eastern and Western Europe, the USA, Latin-America, Asia and Africa, have contributed to this volume. Primary topics are designs for nonlinear models and applications to experimental medicine.