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A collection of 50 of Dr. Mark E. Josephson's groundbreaking journal articles that demonstrate his important contributions as a pioneer and teacher of modern cardiac arrhythmology over the course of 42 years. Each article not only includes a discussion by a peer of the significance of the defining paper, but also includes personal impressions of Dr. Josephson as a clinical scientist, doctor, teacher, role model, and friend.

​This is the first of a three-volume project aimed at providing unique case reports (20 cases per volume) of a large number of supraventricular and ventricular arrhythmias encountered in clinical practice. The book is focused on the treatment of supraventricular arrhythmias, namely focal atrial tachycardias, typical and atypical AVNRT and accessory pathways (both manifest and concealed). All presented-cases were performed using the CARTO electro-anatomical mapping system, which allows the reader to better understand the arrhythmia features due to the high number of images provided. A large number of high-quality figures, which represent the core of the authors'work, enrich the contents: all cases are built around suggestive figures acquired during the patients'hospitalization, which clearly illustrate important concepts used in catheter ablation of cardiac arrhythmias. The figures are not only related to the catheter ablation procedure, but also to the patient history, thus helping the reader to place the invasive treatment of the arrhythmias into clinical context: electrocardiograms, Holter ECGs, signal-averaged ECGs, chest X-Rays, transthoracic and transesophageal echocardiography images, MRI, CT scans, coronary angiography images are provided when considered relevant, in order to better present the patient's condition. Short videoclips with activation maps of the atria or the ventricles during the studied arrhythmia complete the information provided. Teaching-oriented, all chapters include questions and answers and key messages at the end of each case. For this reason, it will be an invaluable tool for cardiologists, clinical cardiac electrophysiologists, and interventional cardiac electrophysiologists in training, but also for all those interested in learning more about the subject.

Part of the renowned Braunwald family of references, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald's Heart Disease provides today's clinicians with clear, authoritative guidance on every aspect of the latest diagnosis and management options for patients with arrhythmias. This comprehensive reference on cardiac arrhythmias lays a solid foundation of the underlying mechanisms of cardiac electrophysiology with an emphasis on identifying, understanding, and treating individual arrhythmias. Now fully updated from cover to cover, and carefully written to provide continuity and a consistent message throughout, the 4th Edition offers unparalleled coverage of cardiac arrhythmias in an accessible and user-friendly manner. - Grounds clinical techniques in basic science for managing patients with complex arrythmia disorders. - Offers increased clinical content with complete diagnostic and management options, including the latest drug-based, device-based, and device-drug therapies. - Covers new tools and techniques for atrial transseptal and percutaneous pericardial access, new ablation energies and tools, and new ACC/HRS guidelines for bradyarrhythmias. - Contains a new chapter on stroke prevention in atrial arrhythmias. - Includes significant content updates on macro-reentrant atrial tachycardias in an era of ultra-high-resolution mapping, new mapping and ablation technologies for ventricular tachycardia, new genetic mechanisms underlying arrhythmia syndromes, and much more. - Provides access to dozens of videos depicting key mapping techniques, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, and atrial septal puncture, as well as pericardial access, cryoablation, and left atrial appendage exclusion procedures. - Uses a consistent format throughout, showing every arrhythmia in a similar manner for quick reference. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This book provides an overview of the history, manifestations, and treatment of heart disease and heart rhythm disorders. In addition, it covers the effects on the lives of patients, coping mechanisms, and relationships with doctors, family, religion, and death. The book uniquely intersects the fields of medicine, literature, science, and art. Chapters begin by familiarizing the reader with the historical aspects of manifestations and treatment – discussing both scientific and psychological aspects of the disease. Chapters also discuss the evolution of several treatment modalities. Every chapter of the book contains interesting and evocative patient stories and their treatment.Rhythms of Broken Hearts will be of interest to a wide spectrum of health care practitioners as well as to patients and related family members with interest in understanding their symptoms and disease entity. _____________________________________________________________________In Rhythm of Broken Hearts, Dr. Gomes distills a multifaceted perspective with a unique story that knits history, physiology, emotion, and wisdom.Jonathan L. Halperin, M.D.If you ever have a broken heart -- romantic or medical -- you will be totally absorbed in this dazzling multicultural read. Grace SchulmanDr. Gomes's affinity and empathy for his patients and their stories narrated in this book, make universal the experiences of illness that we all must navigate at some point in our lives.Jeremy N. Ruskin, MD

This book provides a comprehensive, up-to-date overview of clinical and research aspects of cardiac repolarization geared toward practicing cardiologists and physicians. It analyzes elements of pathophysiology and molecular biology as they relate to the clinical aspects of cardiac repolarization, long QT syndromes, early repolarization syndromes, and special cardiac repolarization syndromes. Each chapter examines different aspects of the field with basic and clinical overviews and highlights the impact on medical management. The book covers a variety of repolarization topics including the influence of the autonomic system, racial and gender differences in patients, the future role of stem cells, inflammation and autoimmunity, and cardiovascular risk. Cardiac Repolarization: Basic Science and Clinical Management is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, clinical cardiac electrophysiology, internal medicine, and cardiovascular biology.

Part of the highly regarded Braunwald's family of cardiology references, Clinical Arrhythmology and Electrophysiology, 3rd Edition, offers complete coverage of the latest diagnosis and management options for patients with arrhythmias. Expanded clinical content and clear illustrations keep you fully abreast of current technologies, new syndromes and diagnostic procedures, new information on molecular genetics, advances in ablation, and much more. Key topics such as inherited channelopathies; atrial fibrillation; ventricular tachycardia; hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, and congenital heart disease. Dozens of videos depicting key mapping techniques, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, atrial septal puncture, and pericardial access, cryoablation, and left atrial appendage exclusion procedures. Grounds clinical techniques in basic science for managing complex patients. Consistent organization, showing every arrhythmia in a similar manner for quick reference. New management options with increased clinical content. Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Dieses praktische Manual beruht auf dem Curriculum des von der Deutschen Gesellschaft für Thorax-, Herz- und Gefäßchirurgie zertifizierten Kurses „Herzschrittmacher-, ICD- und CRT-Therapie'. Prägnant und ausführlich bebildert werden alle Schritte der gefäßschonenden Implantation der Rhythmusgeräte sowie Techniken des Aggregatwechsels vorgestellt. Ein besonderer Fokus des Buchs liegt auf dem Management von Komplikationen, die aufgrund von technischen Defekten an Aggregat oder Sonden, Infektionen oder Perforationen der Aggregattasche auftreten können. Weitere Schwerpunkte bilden Revisions- und Explantationsverfahren sowie kosmetische und funktionelle Aspekte der Geräteimplantation. Ein handlungsorientierter Leitfaden für Herzchirurgen und Kardiologen.

The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions'comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.

Get a quick, expert overview of the many key facets of adult congenital heart disease (ACHD) with this concise, practical resource by Drs. Seshadri Balaji, Ravi Mandapati, and Gary Webb. This easy-to-read reference presents a case-based approach to this fascinating and complex field. - Presents cases provided by ACHD specialists of patients with arrhythmia issues, which are evaluated by an international panel of arrhythmia experts. - Provides commentary and practical guidance on management of complex cases by today's leaders in the field. - Consolidates today's available information and experience in this emerging area into one convenient resource.

Our understanding of the mechanisms and management of cardiac arrhythmias has improved dramatically in recent years thanks to continuing basic research coupled with technological advances.'Fast Facts: Cardiac Arrhythmias'translates this improved understanding into straightforward guidance for managing patients presenting with signs of cardiac arrhythmia. The third edition of this highly readable handbook has been thoroughly updated to include recent pharmacological advances, such as the gradual replacement of warfarin anticoagulation with the novel direct oral anticoagulants. Also discussed are technological advances, including the use of smartphone and smartwatch systems to record heart rhythms, and the latest thinking on catheter and surgical ablation. New chapters have been added on the management of syncope and sudden cardiac death. These complement well-illustrated chapters describing normal conduction within the heart, the underlying mechanisms of arrhythmias and general investigation and management principles, as well as chapters discussing the definition, causes, diagnosis and management of specific arrhythmias. Other highlights include chapters on the rare, but increasingly recognized, inherited arrhythmias, as well as on the use of pacemakers and implantable cardioverter defibrillators. Of interest to primary care practitioners, nurses, medical students, technicians and cardiologists in training, this practical review of the mechanisms of heart rhythm abnormality and the contemporary therapies available provides a useful resource for improving patient care. Contents: • Normal conduction and mechanisms of arrhythmias • Presentation • Syncope • Sudden cardiac death • Investigation • Management principles • Supraventricular arrhythmias • Atrial flutter and atypical atrial flutter • Atrial fibrillation • Ventricular arrhythmias • Rare and inherited arrhythmias • Cardiac devices: pacemakers and defibrillators

This book provides cutting-edge theories and techniques for catheter ablation of all kinds of tachyarrhythmias. Catheter ablation has been a main therapeutic method for tachyarrhythmias for more than thirty years now, and countless operations have been successfully performed. It is crucial for electrophysiologists to diagnose arrhythmia mechanisms correctly and to optimize ablation methods, especially in Japan, one of the world's fastest-aging countries and where many of this book's authors are based.The volume is divided into eight parts. The first three parts present the basic theories and novel insights essential to diagnosing and performing catheter ablations. In turn, the latter five parts highlight practical ablation methods in the context of frequently encountered arrhythmias cases, as well as rare ones such as chanellopathies. Written for electrophysiologists who treat patients with cardiac arrhythmias, the book offers readers essential tips and tricks for the optimal treatment of arrhythmias.

This book provides up-to-date, user-friendly and comprehensive guidance on the evaluation, diagnosis, and medical and surgical treatment of cardiac arrhythmias. This ensures that that this title aids every trainee and practicising cardiologist, cardiac electrophysiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. Cardiovascular Medicine: Cardiac Arrhythmias, Pacing and Sudden Death covers every aspect of cardiac arrhythmias, from cardiac signs and symptoms through imaging and the genetic basis for disease to surgery, interventions, treatment and preventive cardiology. This coverage is presented with consistent chapter organization, clear design, and engaging text that includes user-friendly features such as tables, lists and treatment boxes.

The second edition of Clinical Arrhythmology provides a fresh, clear, and authoritative overview that will guide readers from a solid understanding of the mechanisms behind cardiac arrhythmias -- which is fundamental to their identification -- to diagnosis via electrocardiograms and other tools, to specific management options for each of the arrhythmias that cardiologists and other clinicians will encounter in clinical practice. Organized in a clear, intuitive manner; introducing the reader to an understanding of the anatomical and electrophysiological bases of arrhythmias, then to a comprehensive review of how to diagnose the full range of rhythmic abnormalities, and then to a discussion of specific clinical syndromes in which arrhythmias play a part Highly illustrated chapters ensure key concepts are simpler to understand Detailed appendices provide quick reference values for diagnostic and therapeutic techniques, and pharmacotherapeutic agents, and Recommendations

Concise, compact, fully-illustrated and easy to read, Arrhythmia Essentials, 2nd Edition provides detailed, practical information on recognizing and treating heart rhythm disturbances for clinicians with any level of expertise. The author team, led by renowned authority in cardiac electrophysiology, Dr. Brian Olshansky, guides you skillfully through the different types of arrhythmias and how they present on ECGs. You'll find specific examples of each arrhythmia, numerous algorithms to facilitate an approach to arrhythmia diagnosis and management, updates on medical therapy, and indications for implantable rhythm management devices and ablation – all in a convenient, softcover volume that's perfect for on-the-go reference. - Features a clear, consistent organization that helps you find information quickly: description, associated conditions, clinical symptoms/presentations, and management. - Includes numerous therapy/guideline tables and treatment algorithms. - Offers new coverage of managing arrhythmias during pregnancy and expanded information on athletes and arrhythmias. - Incorporates recommendations based on recent published guidelines. - New! Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Now completely revised and in brilliant full color, Practical Clinical Electrophysiology, 2nd Edition, provides a clinically focused, highly readable approach to the diagnosis and management of arrhythmias. Co-authored by Dr. Peter Zimetbaum, Dr. Alfred Buxton and Dr. Mark Josephson, all affiliated with Harvard University, this practical reference offers concise coverage of the major arrhythmia disorders encountered in the clinic as well as the electrophysiology lab, including pharmacologic treatments. It's an ideal resource for internists, cardiologists, cardiology fellows, and physician extenders who need a complete understanding of electrophysiology but who do not specialize in this area.

A cardiac dysrhythmia is a disturbance in the cardiac rhythm which can be normal (e.g., sinus arrhythmia) or instantly lethal (e.g., sustained ventricular tachycardia). This issue of Critical Care Nursing Clinics of North America will provide state of the art diagnostic and treatment information for cardiac dysrhythmias as well as addressing how to achieve the most accurate diagnostic approach to interpreting an electrocardiogram, which is omnipresent in critical care and of critical importance in diagnosing arrhythmias. Articles in this issue are devoted to: The Normal Cardiac Conduction System; The Normal Electrocardiogram: Resting 12-lead and Continuous Cardiac Rhythm Strips; Premature Beats; Paroxysmal Supraventricular Tachycardia, Including the Special Type Called Wolff-Parkinson-White; Atrial Fibrillation, The Most Common Type of Supraventricular Arrhythmia; Ventricular Tachycardia and Its Disorganized Counterpart, Ventricular Fibrillation; Brady-Dysrhythmias, When Heart Rate Slows Myocardial Ischemia & Infarction and their Relationship to Dysrhythmias; Pharmacologically Induced Dysrhythmias; and Implantable Cardiac Devices and their Role in Dysrhythmias Management.

This issue of Cardiac Electrophysiology Clinics examines Arrhythmias in Cardiomyopathies. Articles include Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy and Its Variants; Role of Cardiac MRI in Risk Stratification of Hypertrophic Cardiomyopathy; Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy; Exercise-Induced Right Ventricular Cardiomyopathy; Dilated Cardiomyopathy; Sarcoidosis; Amyloidosis; Chagas Disease; Fabry Disease; Left Ventricular Hypertrophy: Ventricular Arrhythmias and SCD; Left Ventricular Non-compaction; Mitochondrial Cardiomyopathy and Related Arrhythmias; Arrhythmias in Viral Myocarditis and Pericarditis Cardiomyopathy; Takotsubo Cardiomyopathy; Post-partum Cardiomyopathy; Arrhythmias in Alcohol- and Drug-Associated Cardiomyopathies; Arrhythmias in Neuromuscular Dystrophies; Cardiomyopathies Related to Anti-cancer Therapy– and Radiation- Induced Heart Disease; Arrhythmias After Myocardial Stem Cell Therapy; and more.

This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia development and termination from an entirely new perspective. By viewing the heart as a complex system, the author uses theoretical tools from nonlinear dynamics combined with numerical simulations and experiments to achieve insights into the relationship between its structure and dynamics, thereby paving the way towards innovative low-energy defibrillation strategies. The work tackles, among other things: the effect of substrate heterogeneity on the spatial-temporal dynamics of cardiac arrhythmias and ways in which weak pulsed electric fields can be used to control these dynamics in heterogeneous cardiac tissue. The long-term vision of this research is to replace the current strategy of applying painful and sometimes tissue damaging electric shock – currently the only reliable way to terminate life-threatening fibrillation – by a more subtle but equally effective intervention. The book maps out a number of promising research directions for biophysicists and medical researchers working on the origins and treatment of cardiac arrhythmias.

This issue of Cardiac Electrophysiology Clinics examines Frontiers in Non-invasive Cardiac Mapping. Topics include imaging of heart rhythm disorders, experimental validation and modeling of validation, challenges and future directions of inverse problems, phase mapping of cardiac fibrillation, frequency domain analysis, analysis of diagnostic 12-lead electrocardiography and 3D non-invasive mapping, and many more.

Arrhythmias in Women: Diagnosis and Treatment draws upon the experience of national leaders in the field of women's heart disease to address the unique aspects involved in the diagnosis and treatment of women with arrhythmias and implantable device therapy. Written by distinguished consultants in the Division of Cardiovascular Diseases of Mayo Clinic, this book provides a concise and up-to-date review of the diagnosis and treatment of atrial and ventricular arrhythmias in women. Additionally, this critical book reviews indications for device therapy and management of device complications in women. It is an essential book for health care providers such as internists, cardiologists, and electrophysiologists.

This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.​

​Cardiac Electrophysiology (EP) is a highly specialized, complex and growing field of cardiology. As understanding of the evaluation of treatment of arrhythmias continues to advance, learning and understanding the principles of EP in order to provide the best possible treatments for patients can be a daunting task. The Manual of Clinical Cardiac Electrophysiology is a guide to the clinical diagnosis and treatment of cardiac arrhythmias that meets this need. With a scientific, practical, and multi-disciplinary approach, the book establishes the foundation of the cardiac electrophysiology and provides multimedia illustrations to facilitate and enhance understanding. These illustrations will come directly from real case studies, to provide an authentic look at each principle of EP. Since the world of EP moves so fast, and arrhythmias are diagnosed and treated in real time, it is often difficult to learn EP from static texts, images and diagrams. This book is designed to be accessible enough to serve as an introduction to EP, but advanced enough to serve as a guide for experienced practitioners. EP students of all levels, including medical students, residents, fellows, mid-level providers, nurses, technologist, primary care providers, cardiologists and electrophysiologists will find value in the Manual of Clinical Cardiac Electrophysiology.​

The Cardiac Catheter Book: Diagnostic and Interventional TechniquesLoaded with tips, tricks, and expert solutions to everyday clinical problems, this book is a must for all specialists and trainees performing cardiac catheterizations. It covers basic principles, diagnostic strategies for specific diseases, and the newest interventional techniques, giving readers the tools to successfully manage all types of valvular and structural heart disease.Special Features:Concisely reviews the basics of cardiac catheterization, with sections on indications, risks and complications, patient preparation, equipment and laboratory setup, contrast media, and interpretation of findings Covers the full range of interventional catheter techniques, including percutaneous coronary intervention (PCI), coronary stent implantation, rotational athetectomy, cutting balloon angioplasty, shunt closure, and much more Examines current, evidence-based diagnostic approaches to such commonly seen conditions as valvular disease, cardiomyopathies, coronary artery disease, congenital heart disorders, pericardial disease, aortic dissection, and more Describes key new interventions for structural heart disease, including transcatheter aortic valve implantation (TAVI), interventions for mitral regurgitation (Mitraclip), occlusion of the left atrial appendage (LAA-Occlusion), and renal nerve ablation for resistant arterial hypertension Provides hundreds of illustrations, coronary angiograms, and radiographic images that clarify every concept Demonstrates step-by-step approaches, case studies, and detailed angiographic sequences in nearly 400 helpful videosFrom the fundamentals to the newest therapeutic advances, this book provides the core information needed by every practice performing diagnostic and interventional cardiac catheterizations. It is essential for interventional cardiologists, cardiology fellows, and interventional radiologists who want to quickly increase their knowledge and skills and offer optimal care to their patients.

Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world.Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more!Integrate the latest scientific understanding of arrhythmias with the newest clinical applications, to select the right treatment and management options for each patient.Stay current on the latest advancements and developments with sweeping updates and 52 NEW chapters - written by many new authors - on some of the hottest cardiology topics, such as new technologies for the study of the molecular structure of ion channels, molecular genetics, and the development of new imaging, mapping and ablation techniques.Get expert advice from Dr. Douglas P. Zipes - a leading authority in electrophysiology and editor of Braunwald's Heart Disease and the Heart Rhythm Journal - and Dr. Jose Jalife - a world-renowned leader and researcher in basic and translational cardiac electrophysiology.Access the full text online at Expert Consult, including supplemental text, figures, tables, and video clips.

Whether you are in the lab or the office, stay current in the ever-evolving field of electrophysiology with Catheter Ablation of Cardiac Arrhythmias. Organized by type of arrhythmia, this simple yet comprehensive medical reference book provides detailed information on anatomy, diagnoses, mapping/ablation, and troubleshooting. The book also extensively covers the updated, basic concepts of transcatheter energy applications and currently available mapping/imaging tools for ablation.Improve accuracy with assistance from advanced catheter mapping and navigation systems, and the use of intracardiac echocardiography to assist accurate diagnosis and ablation. Stay current on timely topics like contemporary cardiac mapping and imaging techniques, atrial tachycardia and flutter, atrial fibrillation, atrioventricular nodal reentrant tachycardia, tachycardias related to accessory atrioventricular connections, and ventricular tachycardia, transseptal catheterization, ablation for pediatric patients, and patient safety and complications.Get the most comprehensive and detailed coverage of arrhythmias and ablation technologies, highlighted by a systematic approach to troubleshooting specific problems encountered in the laboratory - complete with solutions. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly chapter format. Master each approach with exceptional visual guidance from tables, illustrations, and high-quality figures.Stay up to date with enhanced and expanded chapters, as well as several hundred new figures, web-based videos, and updated references. Explore recent developments in the areas of atrial fibrillation and ventricular tachycardias. Learn from experts in the field with nearly half of the chapters composed by new authors.Improve content knowledge in relation to anatomy with new chapters focusing on hemodynamic support during VT ablation, rotor mapping in atrial fibrillation, and hybrid procedures.Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.

Recent progress in interventional therapies has revolutionized the management of cardiac arrhythmias, resulting in a remarkable improvement in outcomes for patients. Yet the diagnosis and management of arrhythmias are still viewed as a complex and inaccessible area of modern cardiology.'Fast Facts: Cardiac Arrhythmias'cuts through the technical detail to provide a better understanding of how the patient with arrhythmia presents, and how the problem should be best investigated and managed. Highlights include: • Succinct descriptions with clear well-annotated illustrations of normal conduction and the mechanisms of arrhythmias • A simple classification of arrhythmias based on 12-lead ECG patterns • A comprehensive review of presenting signs and symptoms, with key questions to ask the patient • A logical approach to investigation: predict it (history and examination), wait for it (monitoring) or provoke it (electrophysiological testing) • Practical information on management options: pharmacological therapy, direct cardioversion, catheter ablation and cardiac devices • The latest international guidelines on atrial fibrillation and catheter and surgical ablation • Important pharmacological updates, including the latest thinking on anticoagulation. This highly readable handbook is a practical resource for all primary care physicians, cardiologists in training, cardiac nurses, technicians and medical students seeking a better understanding of the mechanisms of arrhythmias and the contemporary therapies available, with a view to improving patient care. Contents: • Conduction within the heart • Classification and mechanisms of arrhythmias • Presenting signs and symptoms • Investigation • Management principles • Supraventricular arrhythmias • Atrial flutter • Atrial fibrillation • Ventricular arrhythmias • Rare and unusual arrhythmias • Cardiac devices: Pacemakers and defibrillators • Useful resources

Reviews of previous editions:'...a well conceived practical guide to the interpretation and treatment of the main cardiac rhythm disturbances.'—Lancet'This book presents a concise and simplified approach to the diagnosis and management of abnormalities in cardiac rhythm.... One of the book's strengths is the number and quality of electrocardiographic tracings'—New England Journal of Medicine'...this book provides an excellent foundation for all those involved in the care of arrhythmia patients'—British Journal of Hospital Medicine'…would recommend it unreservedly to anaesthetists who wish to improve their knowledge of cardiac arrhythmias'—British Journal of Anaesthesia'This book about cardiac arrhythmias is of much educational value'—European Heart Journal A trusted source for junior doctors, students, nurses and cardiac technicians for over 30 years, the new edition of this classic reference continues the winning formula of previous editions while at the same time incorporating essential new content on today's most important clinical topics, including: Atrial fibrillation: ablation, drugs, rate control versus rhythm control, risk of systemic embolism, prognosis Indications for and management of implantable defibrillators including complications such as arrhythmia storms Indications for pacemaker implantation Anticoagulant therapy (for atrial fibrillation) Long QT syndromes and other channelopathies Recently-approved anti-arrhythmia drugs The 8th edition also features the latest guidelines on ECG screening of athletes and clear guidance for anaesthetists and surgeons dealing with patients with arrhythmias an/or implantable devices. Rich with example ECGs and designed for ease of access to information, Bennett's Cardiac Arrhythmias is the reference you can trust to help you master arrhythmia diagnosis and provide optimal treatment of any patient under your care.

This issue of Cardiac Electrophysiology Clinics covers arrhythmias in athletes, which can be a cause of morbidity and mortality. Expert authors review the most current information available about management of ventricular arrhythmias, atrial fibrillation, bradyarrhythmias, syncope and other conditions. Preparticipation screening, defibrillator use, and prevention are also discussed. Keep up-to-the-minute with the latest developments in this important aspect of cardiac electrophysiology practice.

Cardiovascular diseases are the most important causes of death in the world today. In adults, the most frequent heart disease is acute myocardial infarction, which can lead to sudden death. To prevent these diseases we need to fight against their main risk factors, which include smoking, lipid disorders, hypertension, diabetes and a sedentary life-style, among others. It has been demonstrated that physical exercise or sports at any age provide notable benefits and can help to decrease other risk factors and reduce the incidence of cardio­ vascular diseases. Exercise can be simply walking or cycling. Aerobic exercise con­ tributes to weight loss and also helps to control blood pressure, cholesterol and diabetes. It therefore plays an important role in prevention of heart diseases. Sports for young people are of great value and advisable not only because they con­ tribute to physical fitness but also because they help in psychological well-being. Young people should be encouraged to include general exercise, and particularly sports, into their daily activities. The following points however, should be kept in mind: I. Although winning at a sport is important, this is only so if it is achieved in natural physical conditions and with the correct training. Therefore, it is advisable to keep well away from any type of activity which artificially increases physical performance, that is, drug taking.

This book not only discusses clinical applications, but also links HRV to systems biology and theories of complexity. This publication should be interesting for several groups of clinicians and scientists, including cardiologists, anesthesiologists, intensivists and physiologists. Heart Rate Variability is in principle easy and cheap, making it interesting for all kind of hospitals and private practice. The book will be an example of using translational medicine (bench to bedside) where newest theoretical results are linked to newest clinical research.

…The cardiac unit is a jungle, inhabited by fierce nurses, killer intensivists, marauding attendings, various flesh-eating specialists, sick patients, and lots of arrhythmias. –from the Preface Can you recognize the call of the normal sinus rhythm? Name the natural habitat of Multifocal Atrial Tachycardia or Ventricular Fibrillation? Are you well-versed in the proper care and feeding of Asystole and Atrial Flutter? If you answered “no” to any of these questions, then you need this trusty guide to help you identify and respond to arrhythmias in the veritable wilderness of the busy hospital ward. Created by a seasoned physician educator at a major urban medical center and inspired by the “field guides” used by birders, botanists and the like to identify flora or fauna in the wild, this new book offers a unique – and uniquely humorous -- approach to mastering the ever-vexing challenge of arrhythmia identification. Each arrhythmia is covered beginning with a sample ECG strip, followed by brief text describing its significant characteristics; where and when it is likely to be encountered (its “Habitat”); comments, questions and queries likely to be heard from physicians and other colleagues on the ward (the “Call”); and finally what steps the reader needs to take upon identifying the arrhythmia in a patient (“Care and Feeding”). Dr. Lader's approach brings the sights and sounds of a modern hospital to life, enabling you to understand arrhythmia diagnosis and clinical response in context, and his offbeat, sometimes irreverent humor makes each detail memorable. Fifty self-assessment questions are included to help you master arrhythmia essentials and test your knowledge.

Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

Since Paul Cranefield published his monograph, The Conduction of the Cardiac Impulse, in 1975, much has been learned about the role of the slow inward current in cardiac electrophysiology. Because of this expanse in know­ ledge, both basic and clinical, it appeared reasonable to review in a mono­ graph once again what was known. When Martinus Nijhoff first approached us to undertake the task of updating this information, we were initially reluctant for several reasons. First, we did not feel that the subject could be adequately and thoroughly reviewed, from the cell to the bedside, by a single person. Second, time constraints on all of us precluded even attempting such a task. However, we were encouraged by several of our friends ('egged on'one might even say, since they wished the job done but did not want to do it themselves!) who promised faithfully to contribute chapters on time if we accepted the task. So we did, and most of them did also.

Europace'97 was held in Athens, Greece, on 8-11 June Leads were, as usual, an important topic, with the earl­ 1997 in the city of classical civilisation and learning. iest mention of the then-new polyurethane leads. Future Though now held in modem surroundings and meeting conferences elaborated on these basic topics while pro­ facilities, the influence of the ancient city-state was un­ gressively adding sensors and sensor function, dual­ mistakable, with the architecture and learning of antiquity chamber pacing, and recognising the development of looming over the city, by its influence over the intellectual clinical cardiac electrophysiology. activities of the symposium. The ancient magnificence of Clinical cardiac electrophysiology and compre­ the site was matched by the novelty of modem art and hension of arrhythmias has been largely a development science, Europace is a European symposium, begun in of the twentieth century. With the description and 1979, and has occurred every second year since. Con­ recording of the bundle of His depolarisation, by direct sistent with its importance and continental reach the actual access and by catheter, modem clinical investigation of symposium has moved to different cities throughout arrhythmias and cardiac electrophysiology began. The Western Europe. The first symposium was held in London disciplines of cardiac stimulation and of investigation of and subsequent symposia have been held in Torremolinos, arrhythmias, impulse formation and A V conduction Ostend, Florence, Istanbul and other cities. Because of the were essentially separate for many years.

We were particularly pleased to compile this volume entitled'Clinical Aspects of Cardiac Arrhythmias'. Recent years have seen the publication of many textbooks on cardiac arrhythmias, some of which concentrate on one particular aspect such as drug management, electrocardiographic appearances, electrophysiological evaluation etc; and others of which are the collated reports of symposia, often dealing with detailed con­ siderations of highly specialised problems. Most of the larger more comprehensive texts have devoted a substantial proportion to basic considerations and experimental observations, far removed from the clinical arena. When asked to contribute to the series'Current Status of Clinical Cardiology'we felt that the clinical aspects of cardiac arrhyth­ mias should be emphasized, and that the text should be as comprehensive as possible within the limitations of a single volume in this series. This comprehensive but clinical approach has necessitated the inclusion of certain subjects such as the mechanisms of tachycardia, metabolic aspects of cardiac arrhythmias and reperfusion arrhythmias, which are not directly or exclusively clinical. However, the rapid advances in these areas in recent years are likely to have increasingly important clinical con seq uences. Although the epidemiology of clinical arrhythmias is difficult to dis­ cover, it is widely appreciated that arrhythmias are commonplace.

correction of such a reentry when he observed The W olff-Parkinson-White (WPW) syndrome,... in a favourable experiment, the vigorous the most common variety of preexcitation, has for some time held a fascination for those circulating wave and its instantaneous arrest by interested in clinical electrophysiology because section of the ring is a sight not easily forgotten. it seems to represent a naturally occurring event which, if adequately understood, would un­ Courageous is the only way to describe the mask answers to many fundamental questions first attempt to surgically interrupt an accessory concerning mechanisms and treatment of car­ pathway. The immensity of the feat speaks for diac arrhythmias. Thus, it has been described by itself: Open heart surgery was performed to Scherf and Neufeld [1] as the'Rosetta Stone'divide an invisible stream of electrons! This of electrocardiography. historic event was not anticipated. A fisherman The historic overview of the pre excitation from the coast of North Carolina presented to syndromes will be deferred to Dr. Burchell's Duke University Medical Center in 1968 with authoritative chapter, but a few highlights de­ refractory supraventricular tachycardia related serve emphasis here because they graphically to the WPW syndrome [2]. Attempts to control portray how elements of serendipity, courage, the tachycardia medically failed. Dr. Andrew and luck played important roles in the unfold­ Wallace (then Director of the Coronary Care Unit) had recently returned from the NIH ing of the mysteries of preexcitation.

The new edition of Electrophysiological Disorders of the Heart helps you diagnose and treat a full range of heart rhythm disorders using today's latest technologies and therapies. It provides practical, hands-on coverage of hot topics such as pediatric EP, imaging, echocardiography-guided EP procedures, regenerative therapies, cardiac pacing, and more. Now available in a new full-color format, the title also includes easy online access at www.expertconsult.com.Discover new ways to treat and manage the full range of heart rhythm disorders with content focused on common clinical features, diagnosis, and management. Review expert management strategies to help you handle complex patient problems. Stay current with the latest molecular and technical advances as well as new treatment options implemented over the last few years. Use the latest technologies and devices to accurately diagnose and manage heart rhythm disorders. Consult new and expanded coverage of regenerative therapies, echo-guided procedures, cardiac pacing, and CRT, as well as a new section on pediatric electrophysiology and imaging. Enjoy improved visual guidance with many new full-color images. Log on to www.expertconsult.com to easily search the complete contents online and access a downloadable image library.

Electrocardiography of Arrhythmias: A Comprehensive Review equips you with the core knowledge and clinical competencies you need to accurately interpret electrocardiograms (ECG) and ace the ECG part of cardiology boards or the ABIM ICE ECG certifying exam. Co-written by world-renowned cardiologists Mithilesh K. Das and Douglas P. Zipes, this companion study guide to Cardiac Electrophysiology: From Cell to Bedside offers a concise yet definitive review of electrocardiography, making this is the perfect review and exam prep tool. Obtain a realistic simulation of the actual exam experience. Each ECG is accompanied by a brief clinical history in board format. Review a full range of ECG images - from simple to complex - reflecting both common and rare conditions. Get the most from your board or certification prep by pairing this review with its parent text, Cardiac Electrophysiology: From Cell to Bedside, for detailed explanations and an enhanced learning experience.

Sudden death is probably the greatest challenge facing modem cardiology today. This is mainly due to the impact of its brusque appearance and the socioeconomic implications. The incidende is presently decreasing somewhat, mainly due to the decline in new cases of ischemic heart disease on one hand, and to better preven­ tion in risk patients on the other. Nevertheless, the figures are still high and represent over 300.000 patients per year in the United States alone. This book is an updating of the problem of sudden death from a multifactorial standpoint. It includes not only electrophysiologic data but also covers aspects ranging from epidemiology to prevention. Risk markers and triggering mechanicsms of sudden death are reviewed, with special emphasis on the role of electrical instability, ischemia and depressed ventricular function. The book includes the contributions from many experts, often pioneers in their respective fields. It is our hope that the book serves as an Updating for those cardiologist who are not specialized in these subjects, but may also be of interest to the expert. We wish to express our sincerest gratitude to the authors for sending in their work so promptly, and also Kluwer Academic Publishers for their exactitude and perfection in this edition.

Debates and controversies about how to treat difficult problems or conditions abound in cardiac electrophysiology. This issue attempts to bring together a variety of controversial subjects and to present differing views on how to resolve these questions so clinicians will have a handy guide to the most current thinking about these difficult subjects.

Cardiac Mapping is the cardiac electrophysiologist's GPS. It will guide you to new places in the heart and help you find the old places more easily…a valuable addition to your bookshelf Douglas P. Zipes, from the Foreword. Over the course of three previous editions, this book has become the acknowledged gold standard reference on the electro-anatomical mapping of the heart. This new edition features greatly expanded coverage—the number of chapters have doubled to 80 with 40 new chapters—on leading edge science, new clinical applications and future frontiers, authored by a who's-who of global electrophysiology. This unique text offers truly comprehensive coverage of all areas of cardiac mapping, from core scientific principals to methodological and technical considerations to the latest data that you can put to work caring for patients. In addition, the all new 4th edition adds essential content on: Mapping in experimental models of arrhythmias Mapping supraventricular and ventricular tachyarrhythmias New catheter-based techniques Also featuring a companion website with video clips illustrating essential techniques described in the text The only state-of-the-art, stand-alone text on this dynamic subject, Cardiac Mapping is an essential resource for basic scientists, clinical electrophysiologists, cardiologists and all physicians who care for patients with cardiac arrhythmias.

This issue consists of approximately 50 case studies that touch on different aspects of complex arrhythmias, including atrial fibrillation, ventricular and supraventricular tachycardia, acute MI, and troubles with cardiac devices.

With its unique, singular focus on the clinical aspect of cardiac arrhythmias, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald's Heart Disease makes it easy to apply today's most up-to-date guidelines for diagnosis and treatment. An expert author team provides clear, clinically focused guidance on all types of cardiac arrhythmias, including practical techniques for managing complex patients. Find the information you need quickly with a consistent organization in all chapters, written to a template that shows every arrhythmia type in a similar manner. Access the fully searchable contents online at www.expertconsult.com, in addition to downloadable images and dynamic video clips. Fully understand the rationale for treatment of specific arrhythmias with practical techniques that are grounded in the most recent basic science. Stay up to date with new chapters on molecular mechanisms of cardiac electrical activity, cardiac ion channels, ventricular tachycardia in nonischemic dilated cardiomyopathy, epicardial ventricular tachycardia, ventricular arrhythmias in hypertrophic cardiomyopathy, ventricular arrhythmias in inherited channelopathies, ventricular arrhythmias in congenital heart disease, atrial arrhythmias in congenital heart disease, and complications of catheter ablation of cardiac arrhythmias. View videos of 27 key techniques online, including optical mapping of reentrant ventricular arrhythmias, 3-dimensional mapping of arrhythmias using different mapping and navigation modalities, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, atrial septal puncture, and pericardial access. Gain a new understanding of hot topics such as mechanisms of arrhythmias, electrophysiologic testing, mapping and navigation modalities, ablation energy sources, sinus node dysfunction, conduction disturbances, atrial tachyarrhythmias, preexcitation syndromes and all types of ventricular and supraventricular tachycardias.

Cardiac Mechano-Electric Coupling and Arrhythmias offers a thoroughly reviewed compendium written by leading experts in the field on the mechanism and consequences of cardiac mechano-electrical coupling. Its coverage ranges from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction. Information is grouped into logical sections, from molecular mechanisms, to cell, tissue and whole organ responses, right through to patient-based observations and insight emerging from clinical trials. The information provided carefully highlights both consensus insight and current shortcomings in our understanding of cardiac mechano-electric coupling. The book has been thoroughly revised and expanded since publication of the first edition in 2005, extensively updated to reflect recent developments in the field, and now offers a more balanced view of mechano-electrical interactions in the heart and develops a more clinical focus. Written with the practising cardiologist and junior doctor in mind, it offers interesting new insight for the established physician with an interest in cardiac arrhythmogenesis and heart rhythm management.

Updated to reflect the 2010 ECC guidelines, Pocket Guide for Huszar's Basic Dysrhythmias and Acute Coronary Syndromes, 4th Edition includes ECG components followed by information on how to interpret ECGs to arrive at a diagnosis.

This compendium gives a comprehensive overview of the advances in fibrillation-defibrillation knowledge — recognition of fibrillation as a unique life threatening cardiac arrhythmia; discovery of the electric discharge in its double role of culprit and savior; and technological improved contributions.The book stands on the well-known philosophy of Education-Based on Problems (or EBP), that is, take fibrillation as a medical daily problem and search for that knowledge, technique or principle trying to solve it.The book is interdisciplinary, multidisciplinary and transdisciplinary. It addresses undergraduate and graduate biomedical engineering students, physicians going into cardiology, clinical engineers and clinical engineering technicians, nurses, paramedics and emergency medical personnel.

The study and management of abnormal heart rhythms is the core of Electrophysiology, but the successful identification and management of arrhythmias is important to a much wider range of physicians, from trainees in cardiology to general clinical cardiologists to practitioners in other areas of specialization, for example internists. This book is a thorough overview of clinical arrhythmology designed to help general clinical cardiologists and trainees in the fields of clinical cardiology and electrophysiology achieve the competency they need for clinical practice or for further specialization in the topics covered within the book.

Cryoablation of Cardiac Arrhythmias, by Audrius Bredikis, MD and David Wilber, MD, is the first comprehensive text devoted solely to the effective and appropriate use of cryoablation in the management of cardiac arrhythmias. This user-friendly, all-in-one reference provides clear explanations complemented by abundant, high-quality, full-color clinical photos, and at-a-glance tables making it easy to access the information you need to master even the most challenging cryoablation procedures for adult patients, pediatric/adolescent patients, and cardiac surgery patients.Deepen your understanding of all aspects of cryoablation in cardiac arrhythmias while building your clinical knowledge of the latest technologies and procedures. Master the latest cryoablation procedures for adult patients (AVNRT cryoablation, WPW and septal pathways, atrial flutter, atrial fibrillation, balloon-based cryoablation, RVOT cryoablation); pediatric and adolescent patients (AVNRT cryoablation, WPW cryoablation, cryoablation for pediatric coronary sinus); and cardiac surgery patients (left atrial cryoablation procedure for AF; epicardial cryoablation of AF in patients undergoing mitral valve surgery; epicardial ablation with argon-based cryo-clamp; cryoablation of ventricular tachycardias). Implement truly diverse perspectives and worldwide best practices from a team of contributors and editors comprised of the world's leading experts. Find information quickly and easily thanks to consistent and tightly focused chapters and a full-color design with tables, illustrations, and high-quality images.

The diagnosis and management of heart rhythm abnormalities is often viewed as a complex and inaccessible area of modern cardiology shrouded in technical detail. Fast Facts: Cardiac Arrhythmias demystifies the subject with a straightforward approach to rhythm abnormality, asking how the patient with arrhythmia presents, how the problem should be investigated and how the arrhythmia can be managed. Highlights include: - A succinct description of normal conduction - A simple classification of arrhythmias based on 12-lead ECG patterns - A concise explanation of the mechanisms of arrhythmias with clear well-annotated illustrations - A comprehensive review of presenting signs and symptoms, with key questions to ask the patient - A logical approach to investigation: predict it (history and examination), wait for it (monitoring) or provoke it (electrophysiological testing) - Practical information on management options: pharmacological therapy, direct cardioversion, catheter ablation and cardiac devices - Specific chapters on the different types of arrhythmia

Clinical cardiologists are encountering an important challenge in the caring of families with inherited cardiac diseases. The majority of the inherited cardiac diseases causing sudden death express themselves at variable ages in the form of altered muscle function (i.e hypertrophic or dilated cardiomyopathy) or in the form of arrhythmias (i.e. Brugada syndrome, long QT syndrome). However, it is not uncommon that the first sign of the disease may actually be sudden cardiac death, even before the identification of clear clinical abnormalities. In this last decade, with more than 50 new disease-associated genes identified, the possibility of genetic testing has opened a new opportunity to disease diagnosis and prevention. Clinical and genetic research is continuously on-going not only to identify those at risk, but to better define their level or risk still with limited success.