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This book offers readers a comprehensive introduction to the techniques and application of 3D printing in cardiovascular medicine. To do so, it addresses the history, concepts, and methods of 3D printing, choice of printing materials for clinical purposes, personalized planning of cardiac surgery and transcatheter interventions with patient-specific models, enhancement of patient-physician communication, simulation of endovascular procedures, and advances in 3D bio-printing. The book particularly focuses on the application of 3D printing to improve the efficacy and safety of cardiac interventions, and to promote the realization of precision medical care. The book gathers contributions by an international team of experts in the field of cardiovascular medicine, who combine the latest findings with their own practical experience in using 3D printing to support the diagnosis and treatment of a wide range of cardiovascular diseases. They present in-depth discussions in the fields of congenital heart disease, valvular disease, coronary artery disease, cardiomyopathy, left atrial appendage occlusion, cardiac tumors and vascular diseases.

This book describes the different aspects of aortic valve including comprehensive discussion of the state-of-the-art diagnostic imaging options, disease risk stratification, selection of candidates for valve repair or percutaneous intervention, and most recent therapeutic options. The growing prevalence of valvular heart disease represents a major challenge in terms of short- and long-term management and surveillance. Aortic valve diseases, including aortic stenosis and regurgitation, are among the most frequent of these, while the number of cases of aortic root disease is also on the rise. Aortic valve disease treatment options include valve surgery, valve repair, minimally invasive valve surgery, and percutaneous approaches and all are covered in this volume. Perspective in Aortic Valve Disease is a highly illustrated, case oriented reference aimed at cardiology fellows in training, while also helpful to surgeons, cardiologists, imagers, interventionalists, as well as other clinicians and students involved in the diagnosis and treatment of aortic valve and root diseases.

This book addresses the most relevant imaging techniques in order to detect inflammation and infection in the most common cardiovascular diseases. The book presents data concerning molecular imaging (SPECT and PET) and cardiac magnetic resonance imaging (MRI) for each disease, with a special focus on the emerging role of hybrid PET/MR imaging. Different non-ischemic and ischemic diseases as well as cardiac infections are addressed in detail; these include: Cardiac sarcoidosis, Cardiac amyloidosis, the vulnerable plaque, Post-infarction inflammatory alterations, Pericarditis, Myocarditis, Cardiac devices infections, and Endocarditis. The book also provides a comprehensive discussion on new targets and new tracers, to date mostly investigated at a pre-clinical stage, thus constituting an excellent basis for translational imaging. Imaging of Inflammation and Infection in Cardiovascular Diseases will be of interest not only for experts in clinical imaging, but also pre-clinical scientists and will be invaluable for both nuclear medicine physicians and radiologists.

This book provides a comprehensive practical guide to the plethora of devices that have been developed to support the failing heart. It features easy to follow clinically relevant guidance on mechanical devices used for improving cardiac electrical conduction and cardiac output. Chapters cover indications and implant considerations for the implantable cardioverter defibrillator and cardiac resynchronization therapy devices and hemodynamic monitoring in the intensive care unit. Case-Based Device Therapy for Heart Failure describes how to properly use a range of available devices to treat heart failure. Thanks to its multidisciplinary authorship, it is a valuable resource for practising and trainee heart failure cardiologists, electrophysiologists and cardiac surgeons.

This book explores the history of the Mayo Clinic Cardiac Catheterization Laboratory from 1940 to present day. It examines the life and journey of the Cardiac Catheterization Lab and its ultimate success in implementing the vision of the Mayo philosophy of emphasizing collaboration between lab-based scientists and clinical health care professionals to bring innovation to the clinical practice and lead landmark changes in the practice of medicine profoundly enhancing what we can offer to patients and society alike. The book is divided into decades, with separate sections in each decade on key cardiology topics such as congenital heart disease, coronary heart disease, hemodynamics, pacing, and electrophysiology (EP). Chapters will highlight training, advances, new procedures, new technologies, and fundamental changes to the field throughout the decades, attributed to the work done by Cath lab personnel. Chapters also identify the problems faced, the unmetclinical needs of patients and society, problems solved, and things learned and transmitted into the clinical arena along the way. The Mayo Clinic Cardiac Catheterization Laboratory will be a valuable resource for health care professionals, clinicians, scientists, innovators, administrators, and small and large device manufacturing companies as well as historians and past and present patients.

This book is a treatise on cardiomyocytes, the most important cell for the contractile function of the heart. There has been significant progress in our understanding of the function-related structure, developmental processes and their determinants, mechanisms of cell cycle regulation, post-natal growth, energy metabolism, and reversible and irreversible response of cardiomyocytes to diverse forms of physiological stress and injury. There is also more clarity on the alterations in the biological mechanisms in cardiomyocytes that lead to pathological states and the changes in the cells that occur secondary to disease conditions. Thanks to these advances in knowledge, there have been great gains in attempts to identify disease biomarkers and therapeutic targets for better management of patients with heart diseases. Possibilities to induce regeneration or proliferation of cardiomyocytes and thus repair and or regenerate the damaged heart are also on the horizon.

Providing a critical update and review of salient topics needed for the proper cardiac evaluation and care of athletes, this text is designed to be the most up-to-date and practical manual for all health care providers who evaluate and treat athletes, including sports cardiologists, general cardiologists, sports medicine specialists, team doctors and athletic trainers. The book is divided into three key sections. The first section ​discusses essential topics pertaining to the pre-participation cardiac screening of athletes, providing a framework for how best to perform pre-participation cardiac evaluations and optimize the interpret​at​ion of cardiac screening test results, and ​a guide to ​assist the streamlining of appropriate downstream testing ​when required. The second section reviews the management and care of athletes with specific, existing cardiovascular disorders, providing the reader with fundamental principles to help recognize and advise levels of sport participation to athletes with these disorders. The final section deals with acute sideline management of the symptomatic athlete and will again provide practical algorithms for cardiologists and non-cardiologists alike who are responsible for athlete health and safety in the sports arenas and training facilities. Written and edited by highly regarded experts in the field of sports cardiology, including several cardiologists who are collegiate and professional team physicians and who work with professional sports organizations on developing policies for cardiac screening and monitoring, Sports Cardiology is an excellent practical resource for all clinicians working in the field.

This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with ​cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with ​cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.

This second edition provides an updated review on the current guidelines and practice standards for the clinical management of cardiovascular risk factors and prevention of cardiovascular diseases. Endorsed by the American Society for Preventive Cardiology, this practical textbook includes concise descriptions of major and newer risk factors, biomarkers, and best practices in the management and prevention of cardiovascular disease. The manual contains chapters on the epidemiology and risk factors for a variety of cardiovascular diseases including dyslipidemia, hypertension, diabetes, inflammation, and ischemic stroke. It examines behavioral factors, psychosocial stress, family history, nutrition, physical activity, smoking, alcohol use, and other sociocultural factors. In addition, the book discusses new imaging strategies in detection of cardiovascular disease, prevention of heart failure, atrial fibrillation, and peripheral arterial disease, and prevention for special populations. Throughout the manual, recommendations are based on guidelines endorsed by the American College of Cardiology, American Heart Association, and other major societies. The second edition of the ASPC Manual of Preventive Cardiology is an essential resource for physicians, medical students, residents, fellows, nurses, and other healthcare professionals and researchers in cardiology, primary care, health promotion and disease prevention, exercise physiology, and pharmacotherapy.

This book provides a comprehensive and practical guide to orthostatic hypotension (OH) for doctors and nurses involved in the care of older adults, together with a state-of-the-art update on OH, covering its epidemiology, pathophysiology, assessment, diagnosis, causes, prevention, management, and relevance for geriatric practice. In addition, it addresses mechanisms of orthostatic tolerance and other orthostasis related conditions, as well as drugs, comorbidities and geriatric syndromes related to OH. The homeostatic ability to maintain blood pressure while standing requires an adequate blood volume and the integrity of the nervous system, heart, blood vessels and muscle pump. However, in older adults, some age-related factors can contribute to the development of OH. For example, decreased baroreflex sensitivity, α-1-adrenergic vasoconstrictor response to sympathetic stimuli, parasympathetic activity, renal salt and water conservation, increased vascular stiffness and decreased ventricular diastolic filling, as well as concentrated capacities of the kidney may be associated with changes in postural blood pressure. It has also been shown that OH is associated with falls, cardiac events, heart failure, stroke, reduced quality of life, and increased risk of overall mortality in these patients. “Orthostatic Hypotension in Older Adults” will be of considerable interest to all professionals working in the fields of geriatrics, geriatric psychiatry, neurology, internal medicine, cardiology, and emergency medicine, or working with older people in hospitals or in their community.

This clinically oriented book provides an up-to-date review on the various hybrid imaging modalities that may be employed for the purpose of cardiac imaging. After discussion of generic aspects of hybrid imaging, SPECT/CT, PET/CT, and PET/MRI are each considered in depth. In addition, information is provided on upcoming technologies, such as dedicated so-called fast cardiac cameras (CZT detector technology) and novel probes and radiotracers. A wide variety of topics are addressed, including important technological aspects, possible applications, imaging protocols, peculiarities of the available modalities, radiation exposure, and dose reduction. Last but not least, an estimation of the cost efficiency of dedicated and hybrid imaging devices in cardiology is provided and possible scenarios with respect to health care economics are envisioned. Hybrid Cardiac Imaging will be of particular value for nuclear medicine specialists, cardiologists, and radiologists and will also be of interest to medical physicists, medical technicians, and cardiothoracic surgeons.

This atlas provides a practically applicable didatic case-based guide to the use of cardiac imaging in patient care during and after cancer therapy. It features detailed information on a variety of imaging modalities, including transesophageal echocardiography, magnetic resonance angiography and positron emission tomography. A range of actual patient presentations are included covering both diagnosis and management during curative and palliative surgery, as well as cancer pharmacotherapy with the use of drugs including Trastuzumab, Anthracycline, Cisplatin and Carboplatin. Topics relevant to survivorship are also described. Atlas of Imaging in Cardio-Oncology enables the reader to develop a deep understanding of how to utilise a variety of imaging modalities used in cardio-oncology in a range of scenarios. It provides a critical and timely resource for the trainee and experienced cardiologist, oncologist and radiologist.

This book covers relevant concepts in nuclear cardiology, combining imaging techniques and clinical data to do so. Today, nuclear cardiology is a worldwide discipline connected to the broader field of cardiovascular imaging. The combination of clinical aspects (symptoms, medications, previous cardiac procedures), ancillary exams and nuclear images is key to decision-making in clinical practice. Thus, a book on this topic is essential to provide better outcomes for cardiology patients. The chapters cover a comprehensive range of topics in current cardiology practice, such as ambulatory patients, patients in emergency settings, patients after complex cardiac procedures, and patients during and after the use of cancer therapies that are potentially toxic for the heart (cardio-oncology). As such, multiple clinical scenarios are also presented: patients with suspected coronary disease, patients with heart failure of unknown origin, patients with acute chest pain in the emergencydepartment, patients with suspected pulmonary embolism, patients with complications of the left ventricular assist device, etc. Furthermore, the book describes nuclear cardiology procedures and techniques, discusses the main clinical indications and scenarios for each procedure, presents new technological advances in the field (machine learning and artificial intelligence tools), and mentions the coronavirus disease 2019 (COVID-19) pandemic. Given its scope, the book offers a valuable guide and videos for various medical professionals, especially cardiologists and nuclear physicians.

This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment.Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa.Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

This extensively revised textbook reviews the use of transesophageal echocardiography (TEE) in pediatric and young adult patients with cardiac disease. It reviews how TEE has made a vital contribution to these patients'successful and continually improving clinical outcomes, enabling them to live well into adulthood. The book details the evolving technology and applications of TEE (including three-dimensional TEE), describing how this imaging approach remains at the forefront of clinical practice for pediatric patients and those with congenital heart disease (CHD). Transesophageal Echocardiography for Pediatric and Congenital Heart Disease represents a unique contribution as the only contemporary text to focus exclusively on the clinical application of TEE in children and all patients with CHD. Written by numerous prominent specialists in the field, it presents a comprehensive, modern and integrated review of the subject. Specific chapter topics include the physicsand instrumentation of TEE, structural and functional evaluation, and specialized aspects of the examination, with emphasis on the technical considerations pertinent to both pediatric and adult patients with a variety of congenital and acquired cardiovascular pathologies. Consequently, it serves as a comprehensive reference for the TEE evaluation of CHD, utilizing the segmental approach to diagnosis and discussing the TEE evaluation of the many anomalies encompassing the CHD spectrum. In addition, numerous other relevant topics are discussed, including application of TEE for perioperative and interventional settings. The book is richly illustrated, with many chapters supplemented by illustrative case studies and accompanying videos. A specific section with multiple-choice questions and answers is provided at the end of each chapter to reinforce key concepts. This textbook therefore provides an invaluable and indispensable resource for all trainees and practitioners using TEE in the management of CHD and pediatric patients.

Recent developments in diagnostic and therapeutic aspects of cardiac and neonatal issues have advanced the care of the newborn. In order to achieve excellence in cardiac care, however, close interaction and collaboration of the pediatric cardiologists with neonatologists, pediatricians, general/family practitioners (who care for children), anesthesiologists, cardiac surgeons, pediatric cardiac intensivists, and other subspecialty pediatricians is mandatory. This book provides the reader with up-to-date, evidence-based information in three major areas of neonatology and prenatal and neonatal cardiology. First, it offers an overview of advances in the disciplines of neonatology, prenatal and neonatal cardiology, and neonatal cardiac surgery in making early diagnosis and offering treatment options. Secondly, it presents a multidisciplinary approach to managing infants with congenital heart defects. Finally, it provides evidence-based therapeutic approaches to successfully treat the fetus and the newborn with important neonatal issues and congenital cardiac lesions.This second volume specifically explores issues related to individual cardiac defects, cardiomyopathies, and hypertension and presents a summary and conclusions of both volumes.

Recent developments in diagnostic and therapeutic aspects of cardiac and neonatal issues have advanced the care of the newborn. To achieve excellence in cardiac care, however, close interaction and collaboration of the pediatric cardiologists with neonatologists, pediatricians, general/family practitioners (who care for children), anesthesiologists, cardiac surgeons, pediatric cardiac intensivists, and other subspecialty pediatricians is mandatory. This book provides the reader with up-to-date evidence-based information in three major areas of neonatology and prenatal and neonatal cardiology. First, it provides an overview of advances in the disciplines of neonatology, prenatal and neonatal cardiology, and neonatal cardiac surgery in making early diagnosis and offering treatment options. Secondly, it presents a multidisciplinary approach to managing infants with congenital heart defects. Finally, it provides evidence-based therapeutic approaches to successfully treat the fetus and the newborn with important neonatal issues and congenital cardiac lesions. This first volume specifically explores issues related to perinatal circulation, the fetus, ethics, changes in oxygen saturations at birth, and pulse oximetry screening, diagnosis, and management.

This book provides an invaluable practically applicable and comprehensive manual to coronary artery bypass grafting (CABG) surgery. Critical concepts and techniques are discussed in an easy-to-follow and understand step-by-step guide, featuring a wealth of intraoperative photos and illustrations with concise and instructive descriptions. Topics covered include classical sternotomy, variants of arterial revascularization, off-pump and minimally invasive techniques (MICS-CABG). Operative Techniques in Coronary Artery Bypass Surgery provides invaluable assistance to residents, fellows and trainee surgeons by explaining theoretical and technical aspects of the latest advances in procedural techniques and therapy personalization to optimize CABG surgical outcome. Considering that any heart team depends entirely on the participants'knowledge and their willingness to cooperate, this work allows cardiologists and the other participants of a heartteam to better understand the strengths and limitations of state-of-the-art surgical coronary revascularization. The concepts synthesized within the checklists and decision algorithms provided also enable the reader to develop their knowledge of which technique is the most appropriate for a particular patient.

The second edition of this book provides an overview of electrocardiography from a pathophysiological basis. Refreshed with color illustrations, it incorporates new anatomic and electrophysiologic information as well as updated material on clinical applications of the electrocardiogram (ECG). Intended as a reference for students with a basic understanding of the ECG, the book's focus is to provide the fundamental anatomic and electrophysiologic processes that lead to ECG changes rather than simple pattern recognition. Each chapter has key points and questions with comprehensive explanations so that the reader can assess their understanding of the contents. It can be utilized as a guide – chapter by chapter – or read cover to cover for a complete overview. Case studies are included at the end of the book that integrate the multiple principles of electrocardiography. The Second Edition of ECG Interpretation: From Pathophysiology to Clinical Application is anessential text for medical students, residents, fellows, physicians, and nurses in cardiology and clinical cardiac electrophysiology.

This heavily revised second edition provides a comprehensive multi-disciplinary review of syncope and how to care for these patients successfully. It contains detailed descriptions of the scientific basis behind the pathophysiology of conditions that cause syncope and collapse. Pathways for optimal clinical management in line with the latest guidelines are reviewed and are accompanied by clearly defined recommendations on how to treat patients with syncope. Common procedures and tests are also discussed along with their indications, methodology, interpretation and limitations. Syncope: An Evidence-Based Approach systematically describes the pathophysiology and latest clinical management guidelines for treating patients with syncope. It is an essential resource for a variety of medical professionals including cardiologists, emergency physicians, internists, general practitioners, geriatricians, cardiac electrophysiologists, neurologists and psychiatrists.

Cardiac implantable device (CIED) infections are a key issue since they have serious consequences in terms of morbidity, mortality and associated costs for healthcare systems. Such infections are highly complex, which has implications for prevention (several factors underlie its development), diagnosis (requiring patient specific integration of several elements), acute treatment (choice of the antibiotic, lead extraction procedure), as well as long-term management (CIED re-implantation strategy and follow-up). Dealing with CIED infections requires appropriate organization of healthcare provision, with the creation of integrated hub-spoke referrals, and it has prompted many of the recent developments in CIED technologies: leadless pacemakers, subcutaneous defibrillators, antibacterial envelops and lead extraction devices. This book systematically examines all aspects of this multifaceted condition, discussing each clinical and organizational issue in a separate self-contained chapter. It starts by reviewing the epidemiology/pathophysiology of CIED infections, and then addresses acute and long-term management. Offering a comprehensive overview of the prevention of infections, considering both current and future perspectives, the book also provides practical suggestions along with recommendations from the literature in the field. This is the first book entirely focused on CIED infections. Written by an international team of leading experts it will appeal to broad audience, including cardiologists, electrophysiologists, infectious disease specialists, internists, healthcare professionals, health service managers and providers, researchers and those working in industries involved in the field.

Zur Überbrückung eines akuten Kreislaufversagens wurden in den letzten Jahren unterschiedliche Unterstützungssysteme mit spezifischen Vorzügen und Nachteilen entwickelt. Das Prinzip, die Indikationen zur Anwendung und mögliche Risiken und Komplikationen aller angewandten Systeme (IABP, Impella, TandemHeart, Zentrifugalpumpen, va-ECMO) sind anschaulich und mit zahlreichen Abbildungen von Experten beschrieben. Grundlagenthemen wie die Pathophysiologie des Schocks und das Gerinnungsmanagement werden ebenso berücksichtigt wie spezielle Anwendungen bei Kindern oder für den Patiententransport.

This atlas comprehensively covers surgical techniques for congenital heart surgery. As the population with congenital heart defects increases more and more operations will be required to treat the residual defects, new defects, and replacement strategies such as valve replacements. Chapters are devoted to specific conditions and feature detailed descriptions of how to perform a variety of appropriate reparative surgical techniques; involving complex anatomy, reoperative surgery, and unique techniques to this speciality, enabling the reader to develop a deep understanding of how to successfully resolve situations such as left ventricular outflow tract obstruction, anomalous pulmonary venous return, and anomalous origin of the coronary arteries. Atlas of Adult Congenital Heart Surgery provides a foundational resource for practising and trainee cardiac surgeons, nurses, and healthcare associates seeking specialist training and insight to the resolution of congenitalheart diseases in adults.

•This book presents a selection of over 14 Sections. Each section contains a clinical theme. •Under the umbrella of the theme, there are 78 Chapters, containing specific disease. •Each chapter describes how to interpret and formulate a bedside diagnosis, how to correlate the clinical formulation with imaging and hemodynamic, and how to outline the management. •A discussion on basic investigations such as ECG, chest X-ray, and echocardiography has been made precise. •Cardiac catheterization and hemodynamic data of each disease have been discussed in a very comprehensive and lucid approach. •More than 370 figures, flowcharts, and numerous tables let the reader refer to key facts quickly. •This book summarizes a wide breadth of material from basic to clinical science in one convenient volume.

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with suspected or confirmed pulmonary vascular disease. This book provides a deep dive into the diagnosis and therapeutics of pulmonary hypertension supported by the literature and balanced with personal clinical experience. Expert authors have chosen these specific topics to address issues where uncertainty and/or controversy exists as well as highlight areas that are just being incorporated into clinical practice. These topics include: exercise pulmonary hypertension, sickle cell disease and pulmonary hypertension, and sarcoid pulmonary hypertension, among many others. Chapters address the diagnostic and treatment dilemmas posed by these various clinical entities through literature review, sharing of expert opinion, and review of recent guidelines and their applicability to the multiple different nuanced presentations of pulmonary hypertension. This is an ideal guide for pulmonologists, cardiologists, and other specialty practitioners caring for patients with pulmonary hypertension.

This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.

This thoroughly updated new edition of the classic practical textbook provides a user-friendly, authoritative guide to evaluation of common cardiovascular symptoms and evaluation and management of common cardiovascular conditions. Coverage also includes clinical challenges such as management of chronic anticoagulation, assessing and minimizing cardiac risk in noncardiac surgery, and management of the cardiac surgery patient. Numerous tables and algorithms help readers find information quickly and aid in clinical decision-making.​Practical Cardiology, Evaluation and Treatment of Common Cardiovascular Disorders reflects the current American College of Cardiology/American Heart Association guidelines and provides a concise yet comprehensive handbook presents practical information on the common cardiovascular problems that clinicians encounter daily.

This work offers a comprehensive reference guide to help clinicians in the field of Internal Medicine addressing common aspects of endocrinological disorders in their daily practice. The exponential growth in our knowledge of biomedicine calls for continuous multidisciplinary approaches across specialists and disciplines. In this volume, recognized experts in each given area explore the complex mechanisms linking endocrinological disorders to abnormalities of the cardiovascular system, kidney, liver and gastrointestinal tract, autoimmune, neuro-psychiatric, rheumatic, and dermatologic diseases. Aspects connected to critically ill and elderly patients are examined as well, helping to enhance daily interactions with the most fragile populations observed in clinical medicine. The individual chapters are designed to deliver timely information while explaining pathophysiological mechanisms with the help of figures, flow-charts, and updated guidelines. The book offers a unique and valuable resource for all clinicians, residents, specialists, and physicians involved daily in the management of complex and multidisciplinary systemic diseases.

This book addresses placement and retrieval of inferior vena cava (IVC) filters. Until 2010, utilization of IVC filters had been increasing since their introduction in 1967. Studies in the early 2000's, however, identified that prolonged caval interruption with IVC filters were fraught with complications including filter fracture, migration, and caval thrombosis. This subsequently led the FDA to issue an advisory recommending judicious placement and timely retrieval of IVC filters by treating physicians. This safety advisory ultimately created a heightened awareness by medical professionals and the general public regarding the negative consequences surrounding long-term caval filtration. Subsequently, IVC filter placements decreased nationally while retrievals conversely increased in the post-FDA advisory era. During this same time period, interest in complex IVC filter retrieval also increased as a method to manage patients identified to have or be at risk for complications secondary to prolonged filter implantation.Given these established trends and interest surrounding advanced techniques in IVC filter retrieval, this book addresses these topics in a reader-friendly, case-based format. Chapters focus particularly around the recognition and management of filter-related complications. Additionally, advanced techniques employed by experienced operators for complex filter retrieval are also discussed. For completeness, the book also includes a review of indications and appropriate methods for IVC filter placement. This book is unique in that, at present, descriptions of complications and advanced techniques utilized for complicated IVC filter removal consist mainly of case reports and case series scattered throughout the literature. This publication serves to compile these sources into a single comprehensive entity for physicians treating patients with IVC filters. Chapters are organized to begin with a few introductory paragraphs highlighting the relevant literature (and providing references for in-depth reading) followed by several cases demonstrating tips, tricks, and procedural pitfalls. When possible, each case will include a step-by-step description of the technique being described.This is an ideal guide for interventional radiologists, interventional cardiologists, and vascular surgeons that perform or are interested in performing filter retrieval beyond standard techniques.

This comprehensively revised new edition prepares the reader for the cardiology board examination, as well as provide a concise review of the essentials of general cardiology and the less common but clinically relevant topics in a dynamic and time-efficient manner, augmenting existing learning. It uses board-style questions and answers at the end of each topic, enabling readers to test their learning and commit key concepts to long-term memory. Instructive figures and tables are used to consolidate teaching points. This book also contains practical tips from recent board exam takers and other resources in order to make best use of the reader's limited time. In the MGH Cardiology Board Review, the Editors have compiled the expertise of over 60 experienced authors in a succinct volume, applying methods thoroughly tested in Board Review. In addition, two very important sections on ECGs and images are included, contents of which are derived from the boardexamination answer keys, the very ones that readers are expected to know. Plans on how to best approach board examination preparation and what additional resources to go to are provided. In short, this book has all the strengths to ensure your success on the boards exam.

The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the latest scientific understanding of this multisystemic disease, involving the expertise of specialists including hepatologists, diabetologists, and cardiologists. The respective contributions address various aspects, including the newly released international guidelines, novel diagnostic modalities, and new experimental drugs. The work will appeal to a broad readership, from residents in internal medicine to specialists.​

The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes which directly affect clinical practice and new chapters have been added including Dialysis and Poisoning, Urinalysis/Microscopy and Renal Biopsy. Chapters now include information on key clinical trials for management strategiesAllowing for concise reading on specific topics this book acts as both a quick reference text and study guide. The layout has been designed in a question and answer format in order to promote self-directed learning. Images and diagrams have been further standardized and improved for the new edition and remain a key feature of the book.Clinical Companion in Nephrology, second edition, is an invaluable resource for junior doctors, medical students and renal nurses who encounter renal patients in their daily practice.

This textbook provides a comprehensive, yet practically orientated overview of classic and novel sports cardiology topics, based on current evidence, guidelines, recommendations and expert experience. Numerous publications have provided guidance to these issues, but it has become increasingly difficult for both students and doctors to obtain a thorough, but practicable overview for optimal clinical care of athletes and patients. This book is intended as an educational work, filling the large gaps that are still present in the current educational guidelines for medical students and cardiology trainees. Textbook of Sports and Exercise Cardiology differs from other sports cardiology books by focusing on clear, practical recommendations based on the latest evidence, primarily targeting those who seek professional background information and education that can easily be transferred into everyday care.

The significantly expanded second edition of this important textbook provides a comprehensive overview of the basics of electrocardiography. Each chapter is revised, and the book includes new chapters that focus on pacemakers, low voltage, pulmonary embolism, and hypothermia. The book is intended to help students in all health care delivery fields and at all levels of training to learn the basic concepts of interpreting electrocardiograms. It concisely covers the essential components of electrocardiography (ECG or EKG) and helps readers identify a number of conditions, including arrhythmias, bifascicular blocks, and heart attacks. Chapters are constructed to introduce basic themes, show examples from actual patient tracings, and provide practice through self-test electrocardiograms that reinforce the concepts taught in the chapter. Additionally, practice tracings build on the information provided in earlier chapters as well as on the features of the current one.Designed for the clerkship student, resident, or even the practicing professional who wants to brush up on EKG particulars, the second edition of Basic Electrocardiography is a user-friendly guide to one of medicine's most useful tools.

This thoroughly revised third edition provides a comprehensive grounding on hereditary heart diseases with special emphasis on the genetic aspects of these conditions. It continues to provide the expertise that all cardiologists, clinical and molecular geneticists, and related medical professionals require to provide optimal care for patients with cardiac disease of genetic origin and for their relatives. Topics covered include the different cardiomyopathies, the primary arrhythmia syndromes and the hereditary thoracic aortic disorders. In addition other topics such as cardiac involvement in hereditary neuromuscular diseases, the clinical policy for sudden cardiac death and the possibilities of pre-implantation genetic diagnosis are included to extend the discussion. Clinical Cardiogenetics compiles current knowledge on the topic in an easy to understand reference. It provides a practical clinical primer for cardiologists, clinical geneticists, trainees and other physicians involved in the management of these patients.

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the coretopic: from social and philosophical to gender-related aspects.It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Das Komplikationsmanagement im Herzkatheterlabor systematisch aufbereitet für den angehenden interventionellen Kardiologen und bereits bestehende „Heart-Teams“. Betreuung des Patienten Risikostratifizierung, PatientenvorbereitungRechtssichere Aufklärung und DokumentationNachbetreuung des Patienten Prozedurale Komplikationen PunktionsstellenbezogenBei Drahtplatzierung, KatheterplatzierungPTCA assoziiert, Stent assoziiertMedikamentöses und mechanisches Thrombusmanagement Periprozedurale Komplikationen Hämodynamisches Management, Kardiogener Schock und Verwendung von UnterstützungssystemenAtemwegsmanagementConscious sedation im KatheterlaborKontrastmittelallergie und Kontrastmittel induzierte NephropathieCPR im Katheterlabor Fehlermanagement TeamarbeitFehlerkultur. Was können wir aus der Luftfahrt lernenKonkrete Trainingsempfehlungen, Simulationstrainings Leitliniengerechte Therapie und Ausbildung entsprechend Europäische Gesellschaft für KardiologieDeutsche Gesellschaft für KardiologieEmpfehlungen des Arbeitskreis Simulation der DGK und der AGIK

While there are many outstanding resources providing in-depth review of electrophysiology topics, this extensively updated book is one of the few case-based books that comprehensively cover clinical electrophysiology, devices and ablation. Case review offers a simple, yet effective way in teaching important concepts, offering insight into both the basic pathophysiology of a problem as well as the clinical reasoning that leads to a solution. As the field of cardiac electrophysiology evolves, the challenge remains to educate new generations of cardiac electrophysiologists with the basics as well as the latest advances in the field. Cardiac Electrophysiology: Clinical Case Review collates the most comprehensive case-based reviews of electrophysiology designed to appeal to all students of the field whether they are fellows, allied professionals or practicing electrophysiologists. The Editors have recruited some of the true experts in the field to contribute cases that they have encountered and summarizing the important learning objectives in a succinct way. Covering clinical electrophysiology, device troubleshooting and analysis as well as intracardiac electrogram analysis and ablation, readers will find the cases useful as a review of electrophysiology or in their day to day interactions with patients.

Die Herzchirurgie nimmt einen festen Platz im Behandlungskonzept komplexer Herzerkrankungen ein. Zu den gegenwärtigen Herausforderungen des Fachgebietes gehören die Integration und Bewertung neuer chirurgischer und interventioneller Techniken, sowie der anhaltende Trend zu älteren und multimorbiden Patienten mit höherem Risikoprofil. Mehr denn je erfordern die hohe Patientensicherheit und guten Langzeitergebnisse eine enge interdisziplinäre Zusammenarbeit aller beteiligten Spezialisten.Dieses Kompendium bietet dem Leser eine schnell zugängliche Darstellung der wesentlichen Grundlagen, bewährten Standards und Entscheidungshilfen bei den häufigsten herzchirurgischen Eingriffen im Erwachsenenalter. Dafür wurden die entsprechenden Inhalte von erfahrenen Spezialisten in 20 Kapiteln bearbeitet. Sie umfassen neben allen wichtigen herzchirurgischen Operationen und Techniken auch Kenntnisse über radiologische Verfahren, Rhythmologie und Elektrophysiologie, Psychosomatik, New Technologies, Pulmonalembolie, Lebensqualität und Rehabilitation, Herzersatz und ventrikuläre Unterstützungssysteme sowie Hinweise zum besseren Verständnis von Fachliteratur. In überschaubarem Format und in prägnanter Darstellung lassen sich sämtliche Aspekte der Erwachsenenherzchirurgie auf dem gegenwärtigen Stand der Praxis rasch nachschlagen.Das Kompendium richtet sich an Herzchirurgen, sowie an Kardiologen, Anästhesisten, Radiologen, und an alle Fach- und Hausärzte, die Patienten mit Herzerkrankungen behandeln.

This book provides a guide to the anatomy and the surgical techniques required in thoracic and cardiothoracic surgery. It discusses the advantages and disadvantages of certain surgical procedures in relation to the lymphatic system, thyroid gland, chest wall and parathyroid glands, as well as pulmonary endarterectomy. Further, it addresses intraoperative and postoperative complications, and explores newer fields like microthymectomy, microlobectomy, and pain management for thoracic surgery patients. Providing an update on the latest advances in thoracic surgery, it appeals to general, thoracic, cardiothoracic, and cardiovascular surgeons. It also offers trainees insights into the foundation of the techniques and the relevant anatomy.

This engaging book covers a multitude of topics related to heart rhythm disorders (HRDs) and uniquely familiarizes readers with the development of treatment modalities over the past several decades, including the evolution of anti-arrhythmic drugs, pacemakers, defibrillators, and catheter ablation. Organized in ten sections, this title serves as both an archival and a contemporary resource for clinicians. The first section describes the discovery of the circulatory system by William Harvey in 1628 and outlines the development and understanding of HRD since the advent of intra-cardiac electrophysiology. Subsequent sections discuss the historical evolution of abnormal heart rhythms, such as supra and ventricular rhythms and sudden cardiac death, their treatment with drugs, surgery, pacemakers, implantable defibrillators and catheter ablation. Section nine offers a fascinating narration of the clinical evolution of overcoming heart attacks and its impact on HRDs. Thefinal section explores potential new frontiers in HRD and the factors that may contribute to the prospective rise of cardiovascular diseases. A ground-breaking and invaluable addition to the clinical literature, Heart Rhythm Disorders: History, Mechanisms and Management Perspectives details the pervasive nature of cardiovascular diseases in human history, their ramifications, and their projected effects on at-risk demographic populations and human health in general.

As a leading reference on pediatric cardiology and congenital heart disease, Anderson's Pediatric Cardiology provides exhaustive coverage of potential pediatric cardiovascular anomalies, potential sequelae related to these anomalies, comorbidities and neurodevelopmental problems, and current methods for management and treatment. The fully revised 4th Edition addresses significant and ongoing changes in practice, including recent developments in fetal, neonatal, and adult congenital heart conditions as well as expanded content on intensive care, nursing issues, and societal implications. The outstanding illustration program provides superb visual guidance, and is now supplemented with a remarkable collection of more than 200 professionally curated, author-narrated videos. - Offers authoritative, long-term coverage of a broad spectrum of cardiology conditions, including congenital heart disease, adult congenital heart disease (ACHD), acquired heart disease, cardiomyopathies, and rhythm disturbances. - Features exquisite specimen images by Dr. Robert Anderson and Diane Spicer dissected in easily recognizable analogous imaging planes. These are included in the over 850 anatomic, photographic, imaging, and algorithmic figures, and incorporate new images using virtual dissections of 3D datasets obtained in living patients. - An extensive new section describing the non-cardiac consequences of congenital cardiac disease and other related issues Outside the Heart, including new chapters on quality improvement in congenital cardiac disease, models of care delivery, neurocognitive assessment and outcomes, psychosocial issues for patients and families, ethics, nursing implications, acute and chronic renal complications, and telemedicine. - Three entirely new, expanded sections on the Functionally Univentricular Heart, Fetal Congenital Cardiac Disease, and Heart Failure and Transplantation. - Provides a new focus on patient and family-centered care with expert advice on how to communicate difficult diagnoses to patients and families. - Features new integration of nursing content into all disease-specific chapters, as well as updated content on genetics, congenital heart disease and follow-up, and new imaging modalities. - Contains chapters on new and emerging topics such as MRI and Quantifying the Fetal Circulation in Congenital Cardiac Disease; Congenital Anomalies of the Coronary Arteries; and The Global Burden of Pediatric Heart Disease and Pediatric Cardiac Care in Low- and Middle-Income Countries - Shares the experience and knowledge of an international team of multidisciplinary experts in medicine and advanced practice nursing. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, tables and figures from the book on a variety of devices.

This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.

This book highlights recent technological advances, reviews and applications in the field of cardiovascular engineering, including medical imaging, signal processing and informatics, biomechanics, as well as biomaterials. It discusses the use of biomaterials and 3D printing for tissue-engineered heart valves, and also presents a unique combination of engineering and clinical approaches to solve cardiovascular problems. This book is a valuable resource for students, lecturers and researchers in the field of biomedical engineering.

This book provides a comprehensive overview of exercise physiology in patients with congenital heart disease and other pediatric cardiopulmonary disorders. It begins with an in-depth but pragmatic discussion of exercise physiology and the cardiopulmonary adaptations to physical activity, followed by a review of the conduct and interpretation of cardiopulmonary exercise tests. Subsequent chapters discuss exercise physiology and testing in patients with a variety of congenital heart diseases, including tetralogy of Fallot, Fontan physiology, transposition of the great arteries, aortic valve disease, and coarctation of the aorta. Additional chapters analyze other conditions commonly encountered by pediatric and congenital cardiologists such as pulmonary vascular disease, cardiomyopathies, heart transplants, and metabolic disorders. The book also examines the role of exercise testing in patients with electrophysiologic issues such as Wolff-Parkinson-White Syndrome, long QT syndrome, atrioventricular node dysfunction, and pacemakers. The presentations are enhanced by data from Boston Children's Hospital's vast experience with clinical exercise testing. The textbook concludes with a series of interesting and illustrative cases that build on the earlier chapters, present some fascinating physiology, and provide real-world examples of how exercise testing can inform clinical decision making. Exercise Physiology for the Pediatric and Congenital Cardiologist is a detailed, practical reference for clinicians and other health care providers engaged in exercise testing for children and adults with congenital heart disease and other conditions that may be encountered by the pediatric and congenital cardiologist. It is an essential resource for physicians, medical students, and exercise physiologists as well as researchers in cardiology, pediatrics, and cardiopulmonary fitness..

This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease's pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up.Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice.Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.

This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned.Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.

This textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed. All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College's BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine.

Cardiology is becoming an increasingly complex field understood by only a select group of medical specialists. This publication demystifies many difficult topics in interventional cardiology and cardiac catheterisation, commencing with the basics of laboratory instrumentation and technology and progressing to a comprehensive review of both new and established cardiac interventions.Unlike other publications that are directed mainly towards clinicians, this text is specifically written to assist newcomers such as such as medical trainees, nurses, technicians, scientific staff and other allied health professionals understand the wonders of interventional cardiology, and includes extensive explanations of the techniques of angiography, and new percutaneous. The comprehensive information presented herein, written by recognised specialists in their respective fields, will no doubt prove of great benefit to clinician and non-medical specialist alike.

This book gathers multidisciplinary articles that present advances of our understanding of diseases and the effective treatment of patients. The authors share recent clinical and experimental research findings, highlighting poorly understood areas with uncertain treatment outcomes, such as giant-cell bone tumors and their propensity to metastasize to the lungs; subterranean rehabilitation in pulmonary disorders; male reproductive hormone regulation during physical exercise in hyperbaric, hyperoxic environments, like underwater diving; and amelioration of cognitive decline owing to increased cerebral blood transit time after internal carotid artery stenting. Other topics include new concepts and innovations in the treatment of diabetes in pregnancy, and leg ulcers in chronic venous insufficiency, as well as molecular research on the toxic effects of oxidative stress, impaired cell autophagy, and experimental conditions resembling air pollution. Featuring the latest interdisciplinary advances in biomedicine, this book is a valuable resource for medical professionals, both academics and practitioners, and all allied health-care workers.