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The first edition of Parkinson's Disease and Nonmotor Dysfunction was published in 2005 to provide a source of detailed information that could be readily accessed by the practicing physician. The widely praised first edition described and explained these nonmotor features that had at that point received insufficient attention both in the medical and in the lay literature. Since the publication of the first edition, awareness and knowledge of the nonmotor features of PD has dramatically expanded, calling for a new edition of this important title. Timely, fully updated and expanded, Parkinson's Disease and Nonmotor Dysfunction, Second Edition, offers a state-of-the-art overview of the topic from the same talented group of experienced researchers and clinicians who were the driving force behind the first edition. Importantly, a range of additional aspects of nonmotor dysfunction in PD -- such as dermatological, vestibular, and dental dysfunction -- have been included in this second edition, which remains subdivided into five diverse domains: Behavioral abnormalities, autonomic dysfunction, sleep-related dysfunction, sensory dysfunction, and other aspects of PD such as oculomotor dysfunction, fatigue, and maxillofacial issues. An invaluable contribution to the literature in movement disorders, this revised and expanded collection of contributions by an even larger contingent of superbly knowledgeable authors will further increase awareness of the manifold contributions that nonmotor features may make to the collective clinical picture experienced by the patient with PD.

Jusqu'à il y a une dizaine d'années, la maladie de Parkinson, décrite pour la première fois en 1817, était essentiellement considérée par les médecins, les chercheurs, les personnes touchées par cette maladie et leurs proches sur le versant des troubles moteurs. Ces troubles s'expriment par une lenteur, une raideur et, dans un tiers des cas, par un tremblement de repos. Pourtant, d'autres symptômes peuvent aussi être présents et compliquer la vie au quotidien. C'est le cas des troubles cognitifs qui sont, dans la plupart des cas, subtils et qui se manifestent principalement sous la forme de ce qu'on appelle les troubles dysexécutifs, c'est le cas aussi des difficultés psychologiques comme l'anxiété, la dépression et les hallucinations qui peuvent se rencontrer sur le parcours de la maladie ou encore des troubles du comportement tels que les'addictions'qui peuvent avoir de graves conséquences. Après le succès de La maladie de Parkinson au jour le jour, consacré à la maladie dans sa globalité, les auteurs ont choisi de se focaliser sur ces troubles encore largement méconnus des médecins non spécialistes, souvent tardivement diagnostiqués et pouvant avoir de sérieuses répercussions sur la gestion de la maladie et la vie avec l'entourage. Dans l'esprit de la collection des'Guides pratiques de l'aidant', ce livre a pour objectif de donner des clés au malade mais aussi à ses proches pour : repérer, comprendre et faire face aux troubles cognitifs ; gérer les difficultés psychologiques et mieux vivre au jour le jour la maladie ; limiter les conséquences des troubles comportementaux ; encourager et faciliter la communication sur ces troubles à l'intérieur et à l'extérieur de la famille ; se préserver et trouver des aides pratiques pour assumer son rôle'd'aidant'. Existe en version papier et eBook (tous lecteurs).

Handbook of Non-Motor Symptoms in Parkinson's Disease is designed to provide practical tips and emphasize key priorities for treatment of non-motor aspects of the disorder. The quick-reference handbook format, with key points highlighted by the use of figures and tables, will provide the reader with high-value practical information.

Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder

Parkinson's Disease and Nonmotor Dysfunction fills a major gap in the current rapidly growing body of knowledge concerning Parkinson's disease. Drs. Pfeiffer and Bodis-Wollner have correctly perceived that many nonmotor features of Parkinson's disease are given insufficient attention in the medical literature. Unfortunately, they are often also given insufficient attention by the practicing neurologists who see these patients. As recently pointed out, there is clearly much more to Parkinson's disease than depletion of the nigrostriatal dopamine system (1). Parkinson's disease (not just m- tiple system atrophy) is a multisystem disorder, both pathologically and in its clinical manifestations. This is clearly true for the various motor system abnormalities, which are not fully corrected by dopamine replacement therapy strategies, but also for the nonmotor system abnormalities that are the subject of this volume. Although recently there has been increased awareness of the cognitive, psychiatric, and sleep disorders commonly associated with Parkinson's disease, many of their manifestations remain under-recognized and their importance in managing patients is underestimated. Even less attention is paid to the myriad of other nonmotor disturbances that plague these patients. For example, among the autonomic disorders, although orthostatic hypotension is well recognized, it is usually attributed to dopaminergic medications rather than to effects of the underlying disease. Urologic disorders are also very familiar in these patients, but may not be properly understood or well managed.

1h The 5 International Conference on the Progress in Alzheimer's Disease and Parkinson's 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a joint Congress with the 9 International Catecholamine Symposium. A total of 1258 clinicians and researchers participated in this joint congress 1h from 38 countries in the world. This book represents the proceedings of the 5 Conference on Alzheimer's and Parkinson's disease. The International Conference on the Progress in Alzheimer's and Parkinson's disease was first launched by Professor Abraham Fisher of Israel and Professor Israel Hanin of USA. The first conference was held in Eilat, Israel in 1985. The second conference was organized in Kyoto, Japan in 1989; the third one in Chicago, USA, in 1993, and the fourth one in Eilat, Israel in 1997. The International Catecholamine Symposium (ICS) is an international meeting devoted to the development of basic as well as clinical research on catecholamines. The first Catecholamine Symposium was held in Bethesda, USA in 1958. Since then this symposium has occurred every 5 years. Professor Toshiharu Nagatsu was appointed as 1h the president of the 9 International Catecholamine Symposium, which was to be held in 200 I also in Japan. Therefore, we decided to organize a joint congress of the two meetings, because there is much overlap in research between Alzheimer's disease, Parkinson's disease, and catecholamines. We thank Professor Nagatsu very much for agreeing to organizing this joint congress.

Parkinson's disease and parkinsonism are particular problems in the elderly, causing disability and impairing quality of life. This book covers the clinical features, diagnosis and management of Parkinson's disease in elderly people, dealing not only with the motor symptoms but also problems such as depression and autonomic nervous system dysfunction. It particularly stresses the importance of rehabilitation and total patient care. Topics covered include: • Differential diagnosis and epidemiology • Drug-induced parkinsonism and gait apraxia • The drug treatment of elderly patients • Cognitive impairment in elderly patients with Parkinson's disease • The multidisciplinary rehabilitation team Being a comprehensive, practical and enlightened account of Parkinson's disease in the elderly, and drawing on international experts, this book will appeal to clinicians in the various disciplines involved with neurological disease and rehabilitation in elderly people.