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This text has been written as a practical guide, based on the author's experience over the last 40 years of daily clinical practice and aiming to place the modern approach to the management of infertility in the context of sound theory and evidence-based therapy. It provides the reader with a comprehensive classification of the causes of infertility, their investigation, and their management. This new edition covers many advances in the understanding and management of infertility and other updates to practice--for example, a greater understanding of the pathophysiology of ovarian aging and ovarian reserve testing; the classification of disorders of ovulation and management of polycystic ovary syndrome; the refinement of regimens for superovulation, improved embryo culture systems, and the use of artificial intelligence for the selection of embryos; assessments for endometrial receptivity and management of recurrent implantation failure; pre-implantation genetic testing (PGT) as a therapeutic tool opening up the possibility for aneuploidy screening; as well as the latest thoughts on nutritional health, periconception care, and the exciting new world of the microbiome.

Infertility is a common problem, and it can happen even if you've been pregnant before. In the United States, as many as 15 in 100 couples have trouble getting pregnant. If you are trying to have a baby and have not gotten pregnant, you and your partner may need an infertility evaluation. Exams and tests can be done to try to find the reason why you and your partner have not gotten pregnant. In this booklet, you'll learn how pregnancy works, some possible causes of infertility and multiple miscarriages, what tests you might need, and what treatments are available.

This text offers a succinct overview of the essential clinical applications of ultrasound in infertility management. It will be of benefit to established practitioners in reproductive medicine, as it details the aspects of quality, safety, training, and certification that help improve standards of practice. Those in training or with a special interest in fertility issues will also find it essential reading. Print versions of this book also include access to the eBook version with links to procedural videos.

• A concise and updated text. • All chapters have been revised and new chapters added. • Includes latest evidences, studies and techniques. • Presents clinically relevant and latest information on the subject. • Explores all possible causes of infertility and their management. • Helpful for IVF experts, clinicians, gynaecologists, and postgraduate students of obstetrics and gynecology.

The aim of this book is to focus on the decision making in infertility. Learning is a never-ending endeavor and even more so for a fertility specialist. The field of infertility is ever changing and the percentage of couples approaching us for fertility management is only increasing with time. This book comprised of 20 sections, which include epidemiology of infertility, amenorrhea, ovarian factors, USG in fertility, endoscopy in reproductive surgery, uterine factors, tubal factors, endocrine factors, controlled ovarian stimulation, endometriosis and fibroids, infection in infertility, poor ovarian response, andrology, intrauterine insemination, in vitro fertilization, sperm preparation techniques, advances in ART, difficult scenarios, pregnancy in ART, and other factors in ART, which are further divided into 100 chapters. All the chapters are written in a format of one page algorithm that catalogs the line of action and one page text, elaborating the algorithm. This simple format makes this book as an excellent choice as a ready reckoner for practicing fertility specialists of all spectrums. The beauty of the book also lies in its crisp, clear cut, and extremely practical approach.

Now in an updated edition, this is the most comprehensive book on modern ultrasound imaging in assisted reproductive technology (ART) and reproductive medicine. Fully revised and expanded, it covers emerging technologies possible with the improvement in ultrasound equipment. 3-D monitoring of ovarian follicles, bidirectional vibrant color and Doppler, and improved 3-D and 4-D imaging of reproductive structures are discussed. MRI-guided ultrasound procedures are covered, and comparisons of 3-D imaging with MRI imaging for uterine anomalies is reviewed with an emphasis on the advantages of 3-D performed in the gynecologist's office, and as a less expensive modality.The overall approach of the original edition is maintained, starting with ultrasound safety and technique and diagnosis of the ovary, uterus and fallopian tubes (both normal and pathologic), followed by both male and female infertility and ART treatments and procedures. Ultrasound monitoring of follicular development, the endometrium, and as an aid in embryo transfer to maximize IVF success rates are reviewed. Topics new to this edition include updated information on the diagnosis of benign and malignant adnexal masses, 3-D follicle monitoring, and the diagnosis of adenomyosis and endometriosis, including deep inseminated endometriosis. Additionally, the evaluation of endometrial receptivity, the use of contrasts for fallopian tube patency, controversies regarding septate uterus versus arcurate uterus with the use of 3-D ultrasound, and 3-D ultrasound with saline infusion sonogram and early pregnancy ultrasound are all discussed.An excellent resource for reproductive medicine and ART specialists, gynecologists and ultrasonographers alike, Ultrasound Imaging in Reproductive Medicine, Second Edition covers all that clinicians need to know about the role of ultrasound, from the first time a woman comes into the clinic for treatment, including ART, to early pregnancy monitoring. See better, do ART better.

Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of sperm RNA, the management of subclinical hypothyroidism, and the effects of endocrine-disrupting chemicals. Part three covers the latest in ART, such as evidence-based morphological approaches for embryo selection and culturing human embryos. The final section highlights controversies in reproductive medicine, including the use of preimplantation genetic screening (PGS) and blastocyst transfer, as well as the ethics surrounding a maximum BMI for IVF. Providing an ongoing appraisal of current knowledge, and featuring contributions from leading experts in the field, Emerging Topics in Reproduction, Volume 5 is a worthy addition to the series and an ideal resource on the latest topics for reproductive medicine and REI specialists, OB-GYNS, andrologists, and any clinician working with infertility.

This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition – about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologists and urologists, a useful guide to the diagnostic imaging tests that are essential in treating these patients. The Atlas of Imaging in Infertility is a valuable resource for physicians from different specialties managing cases of infertility.

This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

No Manual da Infertilidade, a paciente com suspeita de infertilidade ou aborto de repetição recebe uma orientação completa desta situação, pela referência em reprodução humana assistida, Professora Dra. Adriana de Góes. O livro detalha a infertilidade tanto feminina quanto masculina, além de doenças que podem oferecer riscos a fertilidade, como a trombofilia e a endometriose. Saiba tudo sobre os principais tratamentos, com a participação de uma renomada psicóloga.

Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology of sport and exercise, which is further elaborated in subsequent chapters on the impact of physical activity, hormonal changes, pathologies, and consequences of drug use for active men and women. Additional chapters address related topics, such as the impact of sport on young athletes and developing reproductive potential, physical activity and pregnancy, the use of oral contraceptives in athletes, oxidative stress, and the impact of nutritional deficiencies on athletes'fertility, with a final chapter providing recommendations and therapeutic guidelines for exercise-related reproductive disorders. Covering everything from the fundamental principles of sports physiology and human reproductive potential to the interaction between physical exercise and the endocrinology of the reproductive system, Exercise and Human Reproduction is an authoritative resource for helping clinicians understand how the reproductive system adapts to activity and exercise and offers strategies to avoidpotential harm to human reproduction.

This unique textbook is designed to provide a summary of state of the art developments in both male and female fertility and its association with cancer for both new and experienced practitioners. Clear, concise and readable, the text allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include demographics of cancer in the reproductive age male, fertility conditions which predispose to cancer development, the role of assisted reproduction for fertility management, as well as fertility preservation strategies for the male and female cancer patients. Cancer and Fertility will be of great value to general urologists, uro-oncologists, gynecologists, medical oncologists, obstetricians, primary care providers, allied health providers.

Now in its fourth volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques and evolving controversies in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. Volume 4 discusses hot topics in contemporary reproductive medicine, including stem cell technologies for male infertility, the current state of ovarian tissue cryopreservation and time-lapse video microscopy of embryos. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like eSET and the use and role of dietary supplements in IVF cycles. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all clinicians and researchers working to help couples resolve their infertility.

Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO's cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

W serii Ginekologia w Praktyce klinicznej ukazują się przewodniki kliniczne, które mają na celu pomóc ginekologom w zapewnianiu skutecznej opieki medycznej wszystkim pacjentkom. W każdym z tomów serii zostało szczegółowo omówione oparte na faktach postepowanie w określonych problemach z dziedziny ginekologii. Zawarte w tekście podsumowania danych naukowych są źródłem wiedzy na temat prowadzonych badań i najistotniejszych publikacji. Dzięki zamieszczonemu na końcu każdego rozdziału obszernemu Piśmiennictwu możliwe jest również pogłębianie wiedzy dotyczącej określonego zagadnienia klinicznego.

In this third volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. This volume includes hot topics in reproductive medicine including age and its impact on fertility, lifestyle factors and reproductive health, fertility preservation for cancer patients, reproductive tourism and a discussion of clinical research design. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like safety of the ICSI procedure and the role of IUI in modern reproductive medicine. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.

Wedding up-to-date scientific information to an understanding of the emotional burdens and ethical dilemmas that inhere in reproductive medicine, Frozen Dreams: Psychodynamic Dimensions of Infertility and Assisted Reproduction provides an overview of the psychology of infertility patients and of the evaluative, administrative, and especially psychotherapeutic issues involved in helping them. The contributors to this volume, who include professionals from nationally prestigious reproductive programs as well as psychotherapists who evaluate and work clinically with infertility patients, explore the complex choices about life and death that are the daily experience of infertility specialists. In voices equally authoritative and intimate, psychotherapists and other health professionals explore the therapeutic process with patients and couples struggling with miscarriage, infertility, childlessness, the possibility of adoption, and the promise of assisted pregnancy. And the contributors are equally attentive to the range of issues that challenge physicians and nurses active in reproductive medicine, intent on providing practical information that will aid decision-making in this demanding area of practice.Written for a large audience of psychiatrists, psychologists, social workers, researchers, nurses, physicians, and general readers, Frozen Dreams is a fascinating introduction to the human face of reproductive medicine. Filled with intriguing and edifying case histories, it will appeal to all mental health professionals who work with adult patients through their childbearing years. For professionals who work inside the complex world of infertility treatment, Frozen Dreams will quickly become an essential text that is turned to repeatedly for information, guidance, reassurance, and revitalization.

Clinical Reproductive Medicine and Surgery offers a succinct overview of both the medical and surgical management of reproductive disorders, as well as coverage of associated imaging modalities. The book includes chapters on major reproductive endocrinology and infertility issues such as polycystic ovary syndrome and amenorrhea, management of endometriosis and fibroids (including interventional radiology), imaging modalities such as ultrasonography and sonohysterography, preservation of fertility, and recurrent pregnancy loss. Residents, fellows, and practitioners interested in reproductive endocrinology and infertility will find this focused and practical text invaluable.

It is estimated that more than 4.5 million couples experience infertility each year, and more than 4 million babies have been born using IVF since 1978. However, assisted reproductive technologies continue to raise many medical, social, ethical, political and religious questions, often leading to controversial and sometimes inaccurate opinions about the outcomes of pregnancies resulting from these techniques. This is the first book dedicated to pregnancies arising from assisted reproductive technologies (ART). Chapters cover the most important management issues, from early pregnancy to outcome of children resulting from ART, including gynaecological, genetic and obstetric complications. Each chapter is written and edited by leading experts in the field of human reproduction. A timely, practical and evidence-based guide to the management of ART pregnancies, based on 30 years of clinical experience, this is essential reading for reproductive and maternal-fetal specialists as well as general obstetricians and gynaecologists.

The book Clinical Infertility and In Vitro Fertilization provides a complete guide for the causes and treatment of infertility. This book is divided into three main sections namely physiology, infertility and assisted reproductive technology. Each section is divided into several chapters and each chapter elaborates the topics that deal with. Nearly 500 clinical and scientific images are illustrated to describe several conditions and surgical techniques. First section starts with male and female physiology and then discusses about various causes of infertility, such as hypothalamic pituitary dysfunction, endometriosis, male factors, the cervical factor, the tubal factor and unexplained infertility. In physiology sections, the basic concept of neuroendocrinology, folliculogenesis, spermatogenesis, fertilization and implantation are explained. The final section discusses about assisted reproductive technology, including In Vitro Fertilization (IVF), cryopreservation of embryos, intracytoplasmic sperm injection (ICSI) and fertility preservation in female cancer patients. The chapter on In Vitro fertilization and related techniques gives the information regarding ovarian stimulation, timing of oocyte retrieval and techniques of oocyte retrieval. The final chapter deals with ethical, moral, religious and controversial issues such as donor gametes.

A little over 12 years ago I wrote a small volume entitled Infertility. It seemed to me at that time that significant advances in the field called for the publication of such a volume. The following is from the preface to that volume: During the past 15 years considerable progress has been made in the field of infertility diagnosis and management. It is perhaps a paradox that much of this increased knowledge has come about because of Western medicine's preoccupation with the search for a means to control reproduction. As a result, we have achieved new insights into the physiologic mechanisms involved in reproduction, and we have found better methods for measuring physiologic changes in reproductive health and disease. To these advances can be added improvements in the utilization of endoscopic and surgical techniques, in the diagnosis and treatment of infections and endometriosis, and in the treatment of hormonal disorders. During this period, too, through workshops and conferences and in journals and texts, these latest advances have been made available to physi­ cians, an outstanding example being the two volumes of Progress in Infer­ tility, edited by Drs. Jan Behrman and Robert Kistner. As necessary as these publications are, they do not offer an overall view of infertility diag­ nosis and management.

There is no clearer testament to the importance and efficacy of in vitro fertilization in the treatmentof the infertilepatient than the fact that over one million babies have been born since its clinical introduction in 1978. The successof this worldwideendeavorhas evolvedto treat some of the formerly most intractable forms of infertility and requires individuals with different skills and insights whose activities are often compartmentalized into clinical, laboratory and research functions. The intent of Essential lVF is to present current issues in clinical IVF that encompass the varied activities of those engaged in this enterprise. By integrating clinical, basic research and laboratory-related aspects of human reproduction, readers with diverse interests should obtain a more complete understanding of the impact, importance and inter-relatedness of each in the progress of infertility treatment, and an appreciation of whether emerging technologies will or should contribute to this progress in the near future. The topics selected for this volume include research that has begun to explain the origins of differential follicular, gamete, embryo and uterine competence, and specific laboratory procedures and protocols that may have important clinical implications forthe generation ofdevelopmentally viable embryos. Human embryoresearchoverthe past 25 years has notonly confirmed that the developmental potential of each embryo is unique, but more importantly, demonstrated how genetic and nongenetic factors for sperm and oocyte determineembryo competencewell before fertilization. Several chapters deal with the origins of normal and compromised gametes and how those with high competence can be identified and isolated for fertilization.

Marc Sedaka stood by while he and his wife endured endless rounds of drug therapies, sixteen artificial inseminations, ten in-vitro fertilizations, three miscarriages, and, finally, a gestational surrogate (“womb for rent”) who carried their twin girls to term. He was as supportive and loving as he could be, but he really wished he'd had a book like What He Can Expect When She's Not Expecting during the process. Most books about dealing with infertility are geared toward women, leaving the man to his own devices when it comes to comfort and encouragement (never a good idea). With the help of his own infertility doctor, Sedaka provides straightforward guy-friendly advice on situations such as: What questions you should ask at the consultations. How to help rather than annoy. What kinds of tests you and your wife should expect. How to console a wife who appears inconsolable. How to enjoy procreation sex. Sedaka's accessible, empathetic voice, combined with the fact that he experienced everything he writes about, makes this a must-have book for any infertile couple.

Help your patients through the maze of infertility treatments Infertility is suffered by around 1 in 7 couples and can be a source of confusion for both partners, providing high stress on relationships. 25% of cases are explained through male infertility, 50% through female infertility, whilst 25% are generally unexplained. The possible causes and solutions are many and complex. Infertility, one of the first in the new Gynecology in Practice series, assists gynecologists and family practitioners to better care for their patients who have trouble conceiving. The authors provide a strong focus on effective diagnosis and management. Following a review of the factors that affect fertility, Infertility takes a practical approach to: Evaluation of fertility Management and treatment Complications Pre-implantation screening Fertility preservation Gynecology in Practice The Gynecology in Practice series provides clinical'in the office'or'at the bedside'guides to effective patient care for gynecologists. The tone is practical, not academic, with authors offering guidance on what might be done and what should be avoided. The books are informed by evidence-based practice and feature: Algorithms and guidelines where they are appropriate''Tips and Tricks'boxes – hints on improving outcomes'Caution'warning boxes – hints on avoiding complications'Science Revisited'– quick reminder of the basic science principles Summaries of key evidence and suggestions for further reading

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2–30% of infertility. The sperm has both autoantigenic as well as isoantigenic potential, and is thus capable of p- ducing antisperm antibodies (ASAs) and sperm-reactive T cells in both infertile men and women. Also, over 75% vasectomized men produce autoantibodies to sperm that can cause a problem in regaining fertility even after successful re-anastomosis in vasovasostomy. Early claims regarding the incidence and involvement of ASAs in involuntary human infertility were probably overemphasized because of unreliable techniques and naivety concerning the complexity of the immune response and antigenic nature of the sperm cell. These factors, the lack of well-designed and controlled experimental studies, and the dearth of effective therapeutic modalities resulted in the confusion of the occurrence and importance of ASAs in human infertility. Consequently, evaluation of infertile couples for ASAs and their possible role in infertility was not considered a signifcant proposition. The development of more accurate assays and the discovery of mucosal immunity capable of responses independent of systemic immunity have caused inclusion of sperm cells and genital tract secretions in the analysis of ASAs.

Infertility is a widespread medical condition. As new technologies emerge, the rate at which our understanding of reproductive medicine grows can be overwhelming. The Biennial Review of Infertility provides the most up to date advances, ideas, and controversies together in one volume. Due to the distinctive nature of infertility, a panel of well-respected experts strives to present each chapter in a clear manner, specifically focused on evidence-based medicine. The Biennial Review of Infertility presents a balanced view of clinically relevant existing information for the evolving areas. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility motivates communication amongst all those working to help couples resolve their infertility.

Das erfolgreiche Buch vom Experten auf dem Gebiet der Kinderwunschbehandlung. Auch in dieser 2. Auflage gibt er seinen Erfahrungsschatz und sein Wissen weiter. Die 2. Auflage ist hinsichtlich der aktuellen Datenlage sorgfältig aktualisiert. Fachlich kompetent, wissenschaftlich fundiert und einprägsam führt der Autor Schritt für Schritt hin zu einer optimalen Beratung für Paare mit Kinderwunsch. Plus: viele Fallbeispiele, konkrete Anleitungen.

Prominent scientists from perinatal medicine, paediatrics, psychology and sociology will meet in Modena, Italy to explore birth as a complex psychological experience for mother, father and child. The proceedings of this interdisciplinary congress are here published in English to reach the broadest possible scientific audience. The goal is to create a dialogue between humanistic and medical perspectives with regard to conception, pregnancy and birth in an era of rapid biotechnological progress, taking different social and cultural contexts into account.

Beratung bei Kinderwunschpaaren? Rationale Diagnostik zur Abklärung bei unerfülltem Kinderwunsch? Therapieoptionen und ihre Chancen und Risiken? Priv. Doz. Dr. M. Ludwig, tätig in einer der größten Kinderwunschzentren, zeigt anschaulich, wie Sie Kinderwunschpaare in Ihrer Praxis betreuen können. Zahlreiche Fallbeispiele demonstrieren, worauf Sie Ihr Augenmerk richten sollten. Schritt für Schritt werden Sie durch die endokrinologische Grundlagen und aktuellen Studien der Reproduktionsmedizin geführt, so dass Sie konkretes Handeln daraus ableiten können. Profitieren Sie für Ihre Praxis vom Erfahrungsschatz eines Experten auf dem Gebiet der Kinderwunschbehandlung!

With the advent of Assisted Reproductive Technologies, our understanding of the reproductive system in both men and women has progressed in an exponential manner.Along with this increase in knowledge has emerged new and advanced laboratories performing unique techniques aimed at diagnosing and treating infertility problems. And as these lab