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From the latest vaccination evidence, recommendations, and protocols... to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as'an indispensable guide to the enhancement of the well-being of our world,'Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. Analyzes the cost-benefit and cost-effectiveness of different vaccine options. Helps you clearly visualize concepts and objective data through an abundance of tables and figures. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Everyone has opinions about vaccines, but what are the facts? This resource provides clear, unbiased, and up-to-date information on vaccination, which protects the world's populations not only from pandemics like COVID-19 but other dangerous diseases as well.Each title in the Contemporary Debates series examines the veracity of controversial claims or beliefs surrounding a major political/cultural issue in the United States. They do so to give readers a clear and unbiased understanding of current issues by informing them about falsehoods, half-truths, and misconceptions—and confirming the factual validity of other assertions—that have gained traction in America's political and cultural discourse.This latest addition to the series is the first reference work on vaccines written through the lens of the COVID-19 pandemic. It asks—and answers—questions raised by the pandemic, such as how vaccines work, what causes side effects, and how COVID-19 vaccines were developed so quickly. It also addresses broader questions, such as how to protect vaccine supply chains and how to prevent public health issues from being politicized. In addition to correcting or clarifying well-known misinformation and misunderstandings about vaccines (such as false claims that they have been linked to autism), this book also provides up-to-date research on ways to counter disinformation and decrease vaccine hesitancy.

A new coronavirus, most likely spilled over from an animal species, has plunged us into the third epidemic of this kind in the last twenty years, against which there were neither vaccines nor therapies.While we argue over the future of humanity, vulnerable to the ecological and environmental degradation that has enabled the pandemic, extraordinary technologies have been developed to combat infectious diseases. In just eleven months it was possible to develop, test and produce the vaccines that are gradually enabling us to escape the SARS-CoV-2 nightmare. In addition, with the legacy of the technologies developed against COVID-19, we will be able to overcome antimicrobial resistance—a slow but inexorable pandemic.As vaccinologists are churning out increasingly precise and effective solutions, vaccine acceptance seems to be receding. Outbreaks of preventable diseases have prompted the health authorities of several countries to make childhood vaccinations mandatory again. Much remains to be done, but a public capable of distinguishing authoritative voices from misleading ones will be able to enjoy the vaccines of tomorrow more widely. Vaccines in the Global Era is an easy-to-read book that can be read by virtually anyone who wants to learn about the importance, effectiveness and safety of vaccines in preventing infectious diseases.Vaccines are cheap, save countless lives, and are more effective than the best medicines. Let's try to make the best use of them for the health of the people and animals living together on this beautiful planet.

Vaccination programmes are of vital importance to public health and are present in virtually every country in the world. By promoting an understanding of the diverse effects of vaccination programmes, this textbook discusses how epidemiologic methods can be used to study, in real life, their impacts, benefits and risks. Written by expert practitioners in an accessible and concise style, this book is interspersed with practical examples which allow readers to acquire understanding through real-life data and problems. Part I provides an overview of basic concepts in vaccinology, immunology, vaccination programmes, infectious disease transmission dynamics, the various impacts of vaccination programmes and their societal context. Part II covers the main field tools used for the epidemiological evaluation of vaccination programmes: monitoring coverage and attitudes towards vaccination, surveillance of vaccine-preventable diseases and pathogens, seroepidemiological studies, methods to assess impact and outbreak investigation. Part III is dedicated to vaccine effectiveness and its assessment. Part IV includes an overview of the potential risks of vaccination and how to study these. Lastly, Part V deals with methods for an integrated assessment of benefits and risks of vaccination programmes. Suitable for professionals working in public health, epidemiology, biology and those working in health economics and vaccine development, Vaccination Programmes also serves as a textbook for postgraduate students in public health, epidemiology and infectious diseases. The book is aimed at all those involved in the many aspects of vaccination programmes, including public health professionals and epidemiologists. Its primary target audiences are master and doctoral students in infectious disease epidemiology and public health, post-doctoral participants of field epidemiology training programmes and public health professionals working in the post-implementation epidemiological evaluation of vaccines and vaccination programmes. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license

Multiple federal agencies, through Operation Warp Speed, continue to support the development and manufacturing of vaccines and therapeutics to prevent and treat COVID-19. As of January 2021, two of the six vaccines supported by Operation Warp Speed have been authorized for emergency use, and vaccine distribution and administration have begun. Effective coordination and communication among federal agencies, commercial partners, jurisdictions, and providers is critical to successfully deploying COVID-19 vaccines and managing public expectations, especially because the initial supply of vaccine has been limited.

This handy visual aid guides clinicians in discussions with patients and parents about the importance of vaccines, the diseases they help prevent and the various vaccines recommended. The chart includes infographics and clinical images to help illustrate why vaccines remain important in preventing diseases. Vaccines covered include influenza, varicella (chickenpox), human papillomavirus infection, polio, meningitis, and much more. The chart also includes information for health care professionals about the origin and nature of the diseases and current recommendations for vaccine schedules.Topics IncludeConsider Simultaneous Administration of Multiple Vaccines for a Happier VisitDiphtheria, Tetanus, and Acellular Pertussis (DTap, Tdap, Td)Haemophilus influenzae Type B (Hib)Hepatitis A and Hepatitis BHuman Papillomavirus InfectionInfluenza (Flu)Measles, Mumps, and Rubella (MMR)MeningitisCommunity-acquired PneumoniaPolioRotavirusVaricella (Chickenpox)

Many infectious diseases are more frequent and are associated with high morbidity and mortality in older adults. Vaccination is the most efficient strategy to prevent infections, and older adults are an important target population for vaccination in order to promote health in this age group. Age-related changes in the immune system as well as other factors, such as comorbidities, obesity or frailty, influence vaccine-induced immune responses in old age. Awareness that vaccines developed for children might not be optimal for adults, and particularly for the older population, has only arisen in the recent past. Vaccination against influenza, pneumococcal disease, and herpes zoster is specifically recommended for older adults in many countries, and various strategies have been pursued in order to optimize these vaccines. However, there are still many pathogens, which severely affect the older population, but for which no vaccines are currently available. Extensive research and development are ongoing to further improve existing vaccines and to design novel vaccines in order to provide protection for this vulnerable age group. In order to exploit the full protective potential of vaccines it is essential to improve vaccine uptake and overcome vaccine hesitancy by providing information and education to stakeholders, health care professionals, and the general public. This book is relevant for researchers working on age-related changes in the immune system or on vaccine development, for health care professionals treating older patients, and for the stakeholders and decision makers involved in vaccination recommendations and implementation.

Vaccines are among modern medicine's greatest triumphs, but popular misunderstandings about vaccines and the communicable diseases they prevent threaten to undo more than a century's worth of progress in public health. Pediatricians, infectious disease specialists, OB/GYN physicians, internists, and family practitioners thus must make patient education about vaccines a routine part of preventative care. THE VACCINE HANDBOOK is a one-stop resource for clinicians whose practices involve administering vaccines. At-a-glance immunization schedules, scripts for addressing patient concerns, and frequently asked questions at the end of each section prepare practitioners to meet challenges such as vaccine hesitancy, correct dosing, and the timing of'catch-up'immunizations with confidence. Covering every clinical scenario from routine childhood immunizations to specialty vaccines for international travel, THE VACCINE HANDBOOK is an essential reference for any preventive care provider. FEATURES · Charts and tables summarizing immunization schedules, proper dosing and storage, and contraindications for commonly used vaccines for quick and easy reference · Vaccination guidelines tailored to special circumstances such as pregnancy, international travel, patients'immunization history, and workplace hazards · Patient education tools including links to reliable online resources and strategies for framing discussions about the benefit of vaccination

Vaccinations provide an effective way to prevent fatal diseases or reduce their symptoms. This book highlights four infectious diseases: polio, tetanus, measles, and mumps. These four diseases are very harmful to human health and are difficult to treat after the infection because they are caused by a toxin or pathogenic virus. In all four cases, the disease exhibits different modes of transmission and progression of symptoms, which require unique treatment regimens. However, all cases can be prevented by vaccinations administered prior to infection.This book summarizes the symptoms and disease progression of all the four diseases and provides information about the toxin or virus that causes each disease. The ability to harness our immune system through vaccination is discussed in the context of disease prevention. Minor and infrequent risks associated with vaccination are also described, but the very dangerous misconception that vaccines cause autism or other major illnesses is strongly refuted.

As the world pins its hope for the end of the coronavirus pandemic to the successful rollout of vaccines, this book offers a vital long view of such efforts—and our resistance to them. At a time when vaccines are a vital tool in the fight against COVID-19 in all its various mutations, this hard-hitting book takes a longer historical perspective. It argues that globalization and cuts to healthcare have been eroding faith in the institutions producing and providing vaccines for more than thirty years. It tells the history of immunization from the work of early pioneers such as Louis Pasteur and Robert Koch through the eradication of smallpox in 1980, to the recent introduction of new kinds of genetically engineered vaccines. Immunization exposes the limits of public health authorities while suggesting how they can restore our confidence. Public health experts and all those considering vaccinations should read this timely history.

Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

The 2009 H1N1 vaccination campaign was one of the largest public health campaigns in U.S. history, vaccinating one-quarter of the population in the first three months. The Institute of Medicine held three workshops in Raleigh, NC; Austin, TX; and Seattle, WA to learn from participants'experiences during the campaign and improve future emergency vaccination programs.

'Provides basic consumer health information about the transmission and treatment of diseases spread from person to person, along with facts about prevention, self-care, and drug resistance. Includes index, glossary of related terms, and other resources'--Provided by publisher.

L'ouvrage aborde le thème des maladies infectieuses (lèpre paludisme choléra etc.) en utilisant une perspective à la fois historique et contemporaine visant à mettre en lumière les nouveaux défis qui y sont liés (SRAS grippe aviaire et porcine etc.). Il regroupe des contributions abordant des approches médicales et sociales sur un même thème : les relations entre les sociétés et les maladies infectieuses. À la fois complémentaires et diversifiés les textes ont été divisés en quatre sections. La première section dresse un portrait des grandes épidémies à travers l'histoire ainsi que des défis actuels qui y sont associés. Une seconde fait le point sur une pathologie infectieuse spécifique c'est-à-dire la tuberculose. Une autre section traite des infections transmissibles sexuellement et une dernière aborde un thème incontournable dans un ouvrage portant sur le risque infectieux : la vaccination. Encore une fois sciences médicales et sociales coexistent ici permettant ainsi de présenter une variété de points de vue et d'expériences sur ce sujet.