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The only reference to focus on the must-know aspects of neurology for psychiatrists, Kaufman's Clinical Neurology for Psychiatrists, 9th Edition, brings you up to date with the knowledge you need to excel on the American Board of Psychiatry and Neurology and other examinations. It fully covers the exam topics you'll encounter, along with new content, high-quality illustrations, and multiple-choice questions. In addition, this book prepares you for clinical work in the 21st century. Discusses timely, clinically-relevant topics such as chronic and acute traumatic brain injury, Alzheimer's disease, correctible causes of dementia, violence, neurologic illnesses that present with symptoms of autism, illicit drug use, stroke, migraine, Parkinson's disease, tardive dyskinesia current treatments, and more. Includes nearly 2,000 multiple-choice questions both in print and online—all written to help you succeed on the ABPN certifying exam. Features new content, new and improved clinical illustrations: life-like patient sketches, anatomy line drawings, CTs, MRIs, and EEGs. Explains each condition's neurologic and psychiatric features, easily performed office and bedside examinations, appropriate tests, differential diagnosis, and management options. Correlates neurologic illnesses with the DSM-5.

Cauda Equina Syndrome is the authoritative text on this most vital aspect of musculoskeletal medicine. Both practical and readable, it is an essential read for doctors, physical therapists and chiropractors.

Neuroscience for Clinicians is a comprehensive and clinically relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms. By emphasizing how genetic, molecular, and cellular processes and their interactions control the function of the nervous system, the work will help clinicians understand emerging concepts about the mechanisms of neurologic disorders including neurodegeneration, channelopathies, and synaptic dysfunction that provide potential therapeutic targets. This single-authored textbook utilizes ample figures and tables throughout in order to facilitate retention of the core concepts presented. Divided into 5 sections, the first section includes chapters focused on basic cellular processes. Section 2 includes chapters focused on cell communication while Section 3 focuses on the neuronal microenvironment. The fourth section focuses on the organization and interactions of circuits in the cortex, thalamus, and brainstem, underlying behavioral states such as sleep, sensory processing, and motor control. The fifth section addresses mechanisms of pain and neural control of survival. And the final section covers concepts on mechanisms of emotion, social behavior, memory, language, and executive functions with emphasis on dementia and behavioral disorders.

This book provides a comprehensive review of recent developments in the field of motor neuroprosthetics and brain-machine interfaces. Chapters in this book are provided by leading experts in the field and include topics such as the design and control of multidimensional prosthetics and exoskeletons, deep brain stimulation, functional electrical stimulation, deep learning for brain machine interfaces, biofeedback, and cognitive intent for adaptation of motor prostheses. This book is a great resource for undergraduate and graduate students, researchers, engineers from related disciplines, entrepreneurs, and anyone interested in the latest progress in the field of motor neuroprostheses.

The main purpose of this book is to provide the reader with a better understanding of spinal nerve root injuries caused by various pathologies (e.g. disc herniation, space-occupying lesions, trauma etc.).The standard anatomical description of spinal nerve roots origin, course and arrangement (described in the first chapters of the book) is now strongly influenced by the frequent findings of their intraspinal extradural and intradural connecting branches and by other variations, which are considered to be the major cause of the surgical therapy failures. Intraspinal extradural and intradural neuroanatomical roots variations may affect in fact the clinical picture, diagnosis, and surgical treatment; their recognition can minimize the damage to neural structures in the spinal anaesthesia, in spinal operations, in spondylosurgery, in endoscopic surgery, laser discectomy, etc. Their aetiology is unknown and it has to be elucidated, and they arerarely found during the usual preoperational examinations, a reason that encouraged various anatomical dissection studies finalized to their description. The data shown in this book will be surely helpful for traumatologists, orthopaedists, spinal surgeons, neurosurgeons, plastic surgeons and for all those dealing with intraspinal variations of nerve roots.

In 35 chapters written by the editors and a team of internationally renowned contributors, the book covers the underlying principles of osteopathic palpation from a biodynamic and'morphodynamic'perspective, and their application in the cranial field and the spinal cord.It emphasises the importance of considering not just the patient's physical self, but also the inner consciousness. It teaches how to assess tissue-energy characteristics, and to use this understanding in managing the whole patient.The work discusses biophysical, neurobiological and psychological interactions as well as the interplay of developmental dynamics and further epigenetic influences on the organism.As well as the primary respiratory mechanism, various biological rhythms play an important role within osteopathic treatment; the book explores new insights that flow from chronobiology and rhythm research.All osteopathic practice develops on conceptual foundations. Acknowledging the importance in the practice of osteopathy of such theoretical underpinning, the book discusses osteopathy with regard to the development of paradigms within the healing arts as well as from various philosophical viewpoints - such as postmodern, system-theoretical, Goethian and phenomenological. It examines thoroughly the multi-layered dynamics of development of human beings interacting with their environment.The resulting implications for therapeutic interaction as well as principles of diagnosis and treatment form the core of the book. These fundamental principles are then specifically applied to the cranial sphere. This section focuses primarily on the treatment of the brain, as well as the developmental dynamics of the relations of the midline, cranial bones, dural structures, vessels and cranial nerves.

This invaluable resource explores the regenerative potential of stem cells in the nervous system, with a focus on clinical applications. The expertly authored chapters discuss cell-based therapies for spinal cord injury and regeneration, traumatic brain injury, glioblastoma, Parkinson's Disease, ischemic stroke, cell banking, human embryonic stem cells and related concerns, harvesting of adipose tissue, and more. These topics are contextualized within a discussion of future directions of these therapies. Neurological Regeneration, part of Springer's Stem Cells in Clinical Applications series, is essential reading for scientists, researchers, advanced students and clinicians working in stem cells, neurology, regenerative medicine or tissue engineering.

For more than 35 years, Kaufman's Clinical Neurology for Psychiatrists has been the only reference to focus on the must-know aspects of neurology for psychiatrists. Now in a revised 8th Edition, this classic text brings you up to date with essential knowledge in clinical neurology with new topics, new illustrations, and new questions to help you excel on the American Board of Psychiatry and Neurology examination. Explains each condition's neurologic and psychiatric features, easily performed office and bedside examinations, appropriate tests, differential diagnosis, and management options. Discusses timely, clinically-relevant topics such as traumatic brain injury, Alzheimer and non-Alzheimer dementias, other age-related neurologic conditions, neurologic illnesses that present with symptoms of autism, neurologic effects of illicit drug use, and current treatments. Correlates neurologic illnesses with the DSM-5. Includes nearly 2,000 multiple-choice questions both in print and online, – all written to help you succeed on the ABPN certifying exam. Features new and improved clinical illustrations throughout: life-like patient sketches, anatomy line drawings, CTs, MRIs, and EEGs that demonstrate clinical features.

An Atlas for the 21st Century The most precise, cutting-edge images of normal spinal anatomy available today are the centerpiece of this spectacular atlas for clinicians, trainees, and students in the neurologically-based medical specialties. Truly an ìatlas for the 21st century,î this comprehensive visual reference presents a detailed overview of spinal anatomy acquired through the use of multiple imaging modalities and advanced techniques that allow visualization of structures not possible with conventional MRI or CT. A series of unique full-color structural images derived from 3D models based on actual images in the book further enhances understanding of spinal anatomy and spatial relationships. Written by two neuroradiologists who are also prominent educators, the atlas begins with a brief introduction to the development, organization, and function of the human spine. What follows is more than 650 meticulously presented and labelled images acquired with the full complement of standard and advanced modalities currently used to visualize the human spine and adjacent structuresóincluding x-ray, fluoroscopy, MRI, CT, CTA, MRA, digital subtraction angiography, and ultrasound of the neonatal spine. The vast array of data that these modes of imaging provide offer a wider window into the spine and allow the reader an unobstructed view of the anatomy presented to inform clinical decisions or enhance understanding of this complex region. Additionally, various anatomic structures can be viewed from modality to modality and from multiple planes. This state-of-the-art atlas elevates conventional anatomic spine topography to the cutting edge of technology. It will serve as an authoritative learning tool in the classroom, and as a crucial practical resource at the workstation or in the office or clinic. Key Features: Provides detailed views of anatomic structures within and around the human spine utilizing over 650 high quality images across a broad range of imaging modalities Contains several examples of the use of imaging anatomic landmarks in the performance of interventional spine procedures Contains extensively labeled images of all regions of the spine and adjacent areas that can be compared and contrasted across modalities Serves as an authoritative learning tool for students and trainees and practical reference for clinicians in multiple specialties

Entré dans la langue française aux environs de 1690 sous la forme, aujourd'hui caduque, de « névrologie », le terme de neurologie, utilisé à partir de 1732 pour désigner la branche de la médecine qui étudie l'anatomie, la physiologie et la pathologie du système nerveux – et principalement du cerveau –, reçut sa consécration officielle de...

Stemming from a 2012 conference entitled Brain Degenerations and Emerging Mental Health Challenges in Sub-Saharan Africa, this book is aimed at both the general practitioner interested in CNS disorders, and the specialist who would like to know more about CNS pathology in Africa. By employing a broad defi nition of what brain degeneration means, the authors are able to touch upon everything from dementias and CNS malignancy to traumatic brain injury and CNS infective processes.This book draws from and builds upon the original conference presentations, and incorporates the most up-to-date science behind brain degeneration as well as actual case reports. Each of the book's six sections off er the reader a deeper understanding of brain degeneration as it exists in Sub-Saharan Africa.

Crash Course – your effective every day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have all the core information you need in one place to excel on your course and achieve exam success. A winning formula now for over 15 years, each series volume has been fine tuned and fully updated, with an improved layout tailored to make your life easier. Especially written by senior medical students or recent graduates – those who have just been in the exam situation – with all information thoroughly checked and quality assured by expert faculty advisers, the result are books which exactly meet your needs and you know you can trust. This highly accessible volume provides a strong foundation in understanding the essential basic neurosciences and the clinical investigation of the nervous system. Commencing with'Learning Objectives', every chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. More than 160 illustrations present clinical, diagnostic and practical information in an easy-to-follow manner Friendly and accessible approach to the subject makes learning especially easy Written by students for students - authors who understand exam pressures Contains ‘Hints and Tips'boxes, and other useful aide-mémoires Succinct coverage of the subject enables ‘sharp focus'and efficient use of time during exam preparation Contains a fully updated self-assessment section - ideal for honing exam skills and self-testing Self-assessment section fully updated to reflect current exam requirements Contains ‘common exam pitfalls'as advised by faculty Crash Courses also available electronically! Online self-assessment bank also available - content edited by Dan Horton-Szar!

This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system. Offers a unique emphasis on the neurological manifestations of diabetes Provides thorough coverage of the clinical, experimental, mechanistic, therapeutic, peripheral, and central aspects of diabetic neuropathy Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Until recently, it was thought that the adult brain is modifiable only during early stages of ontogenesis. However, neurophysiological and neuroimaging studies now indicate that the mature human brain is, under certain conditions, capable of substantial neuroplastic changes. Neuroplasticity reflects the ability of the human brain to alter the pattern of neural activation in response to previous experience, and recent findings indicate that the effects of experience can lead to both structural as well as functional reorganization. It has been shown that pathological neuroplastic changes can be reverted/normalized and that the modulation of the neuroplastic changes can be paralleled by improvement of the patient's status. However, there is a gap between the potential of neuromodulation, technical progress and actual preparedness of medical personnel to provide this type of treatment. A prevalent opinion among medical professionals indicates that training programs and educational materials in neuromodulatory techniques are well needed and appreciated. Neuromodulation will focus on the description and discussion of methods currently available for invasive and non-invasive neuromodulation, their clinical potential, significance and practical applications. In order to facilitate understanding of the topic, the initial part of the textbook will review neurophysiological systems involved in neuromodulation and will provide readers with basic principles of neuroplasticity that constitutes the rationale for neuromodulation in human medicine. Additionally, the clinical use of these techniques will be described with special regard to safety and avoidance of complications.

Scientists have speculated as to the nature of cerebrospinal fluid (CSF) -'the third circulation'or'vital spirit'for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an'animal spirit'directing all our activities, as thought by Galen (Singer, 1956) or but a'modified tap water'(Halliburton, 1917)? With the advent of lumbar puncture, cerebrospinal fluid has become a readily available and important means of studying disease affecting the nervous system. In recent years, many sophisticated tools including com­ puter guided gas chromatography/mass spectrometry and high performance liquid chromatography have made it possible to identify and quantify many constituents of this fluid. The CSF has an enormous, though largely'untapped', potential in aiding diagnosis and evaluating treatment of many neurological, psychiatric and systemic disorders. As the ependyma is only a diffusional barrier between the CSF and extracellular fluid of the brain for many compounds, changes in the concentration of these compounds in the CSF may reflect disease processes in the brain.

MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

Pío del Rio-Hortega, one of the pioneering neuroscientists and discoverer of microglia, has been recognized as one of the most important Spanish neurohistogists of the past century. His landmark research on oligodendroglia, originally published in Spanish in 1928, has been translated into English for the first time by Dr. José R. Iglesias-Rozas and Prof. Manuel Garrosa. The book establishes definitively the concept of oligodendroglia and describes in great detail its structure, varieties, function, origin and pathology, providing a thorough review. The entire 1928 writing is presented, including the 79 excellent drawings and photographs from the original publication. To complement the original book and provide historical context, the translators have also included an introduction to the research and a biography of Pío del Rio-Hortega. This book constitutes a milestone in the history of neuroscience, biology and medicine, and it will be valuable reading for researchers and practitioners in these fields. First English translation of seminal 1928 research Contains the broad descriptions and interpretations of the normal and pathological oligodendroglia Full original text and new introductory sections

Stroke Rehabilitation: Insights from Neuroscience and Imaging informs and challenges neurologists, rehabilitation therapists, imagers, and stroke specialists to adopt more restorative and scientific approaches to stroke rehabilitation based on new evidence from neuroscience and neuroimaging literatures. The fields of cognitive neuroscience and neuroimaging are advancing rapidly and providing new insights into human behavior and learning. Similarly, improved knowledge of how the brain processes information after injury and recovers over time is providing new perspectives on what can be achieved through rehabilitation. Stroke Rehabilitation explores the potential to shape and maximize neural plastic changes in the brain after stroke from a multimodal perspective. Active skill based learning is identified as a central element of a restorative approach to rehabilitation. The evidence behind core learning principles as well as specific learning strategies that have been applied to retrain lost functions of movement, sensation, cognition and language are also discussed. Current interventions are evaluated relative to this knowledge base and examples are given of how active learning principles have been successfully applied in specific interventions. The benefits and evidence behind enriched environments is reviewed with examples of potential application in stroke rehabilitation. The capacity of adjunctive therapies, such as transcranial magnetic stimulation, to modulate receptivity of the damaged brain to benefit from behavioral interventions is also discussed in the context of this multimodal approach. Focusing on new insights from neuroscience and imaging, the book explores the potential to tailor interventions to the individual based on viable brain networks. This book is intended for clinicians, rehabilitation specialists and neurologists who are interested in using these new discoveries to achieve more optimal outcomes. Equally as important, it is intended for neuroscientists, clinical researchers, and imaging specialists to help frame important clinical questions and to better understand the context in which their discoveries may be used.

Behavioral neurology is founded on lesions of cortical gray matter, but recently the contributions of cerebral white matter to cognitive and emotional dysfunction have also attracted attention. The Behavioral Neurology of White Matter surveys this broad and fascinating field from a clinical perspective. Stimulated by recent improvements in neuroimaging, white matter has been carefully studied, and its role in the operations of cognition and emotion clarified by correlations with clinical observations. The relevance of normal and abnormal white matter to behavioral neurology is apparent in every context where this question has been examined: in development, aging, and in a host of diseases, intoxications, and injuries. Since the first edition of this book in 2001, steady advances have been made in understanding the neurobiology of white matter and its clinical significance; this edition provides a comprehensive update on this rapidly expanding field. Every chapter has been extensively rewritten, including a comprehensive revision of the account of the neuropsychiatry of white matter, a particularly challenging area. The syndrome of white matter dementia is discussed in detail, and its refinement with new information is considered along with the proposal of mild cognitive dysfunction as a precursor syndrome in many clinical settings. In addition, two new chapters have been added, one on the emerging area of white matter changes associated with neurodegenerative disorders such Alzheimer's Disease, and another on neurologic aspects of white matter including intriguing new information on white matter plasticity. A unifying theme is the concept of connectivity, as it is clear the white matter forms an essential component of the widespread distributed neural networks by which cognition and emotion are organized. In addition to the microconnectivity within gray matter that subserves information processing, the macroconnectivity of white matter enables information transfer - both are critical for the functions of the human mind.

This volume focuses on the interplay of mind and motion-the bidirectional link between thought and action. In particular, it investigates the implications that this coupling has for decision making. How do we anticipate the consequences of choices and how is the brain able to represent these choice options and their potential consequences? How are different options evaluated and how is a preferred option selected and implemented? This volume addresses these questions not only through an extensive body of knowledge consisting of individual chapters by international experts, but also through integrative group reports that pave a runway into the future. The understanding of how people make decisions is of common interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. So far, however, it has mainly been advanced in isolation within distinct research disciplines; in contrast, this book results from a deliberate assembly of multidisciplinary teams. It offers intense, focused, and genuine interdisciplinary perspective. It conveys state-of-the-art and outlines future research directions on the hot topic of Mind and Motion (or embodied cognition). It includes contributions from psychologists, neuroscientists, movement scientists, economists, and others.

Every chapter has been updated to reflect current thought and research in the field. Chapters devoted to specialized tests in neuropsychology have been updated to reflect new editions of these popular instruments. Special topic chapters have been added such as working in pediatric coma rehabilitation, using the planning, attention, sequential, simultaneous theory of neuropsychological processes, additions on ADHD, and more appear written by the leading experts and practitioners in these fields to reflect the demands of current practice in clinical child neuropsychology.

This book presents the latest findings in mechanosensitivity of the nervous system. The nervous system stands out from a number of tissues because besides reacting to the mechanical stress it is transmitting its own response to other organs and tissues, which are located downstream of its signaling pathway. For this reason any type of mechanical stimulation of the nervous system, which is capable of triggering a physiological response, has high scientific and practical significance, since it allows its use beyond a particular experimental model anywhere where it is contributing to a particular pathological condition. This book is a unique collection of reviews outlining the current knowledge and the future developments in this rapidly growing field. Currently, investigations of the effects of mechanical stress on the nervous system are focused on several issues. The majority of studies investigate the effects of mechanical stimulation on mechanosensitive channels, as its primary target and interactive agent, and aim on description of downstream intracellular signaling pathways together with addressing general issues of biomechanics of the nervous system. Knowledge of biomechanics, and mechanisms, which underlie it on organism, organ, tissue and cellular level, is necessary for understanding of the normal functioning of living organisms and allows to predict changes which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. The book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

An enormous number of neurons in the brain form neural circuits by creating s- aptic bonds with other neurons. Many of those circuits come together and function as a system. To clarify the function of the human brain, a study needs to be dev- oped as a whole, not merely at the molecular, cellular, or systemic level. With the development of neural science, knowledge of the molecules and neurons that comprise the brain has increased exponentially in the last two decades. The mysteries of human brain function are being solved in sequence with the use of the latest medical technologies such as PET, fMRI, MEG, and TEM, and in this way, research in neural science is making rapid progress. Springer Japan has given me the opportunity to publish this book, Novel Trends in Brain Science, which introduces the most important and latest knowledge in neural science on brain function imaging, learning, memory, emotions, and pain. In particular, the relationship between well-developed oral cavities and highly advanced brain function is an extremely new and unique area of study and is expected to become an entirely new? eld. As of 2006, two Japanese–Taiwanese joint conferences on neural science have been held, in Gifu Prefecture (Japan) last year and in Taipei this year. In this book I have collected original research introduced by neuroscientists representing both countries at those conferences, and I am con? dent that the work brought together here will promote further research on the human brain.

Incorporating a strong application to real clinical problems, this fifth edition of Mayo Clinic Medical Neurosciences provides one of the most contemporary and succinct teaching approaches to the current status of basic neuroscience knowledge. Highlights of the Fifth Edition: A succinct format provides readers a quicker way of learning the most important elements of medical neuroscience A focused application to clinical medicine reinforces neuroscience concepts and improves retention A strong emphasis on critical developments in neuroscience, including neurochemistry and genetics, ensures readers are up to date on essential advances Skillfully rendered full-color illustrations detail the core focus of anatomy and systems throughout the text Setting a standard for excellence in introductory medical neuroscience education, the book presents use unique skillbuilding methods that facilitate learning through problem solving, while keeping readers engaged and focused.

Human Neuroanatomy provides a thorough and comprehensive overview of the human brain and spinal cord for medical and graduate students as well as residents in the clinical neurosciences. Standing on the shoulders of training from outstanding scientist-teacher mentors and based on more than 30 years of experience teaching about the brain and spinal cord to medical and graduate students, this single authored text presents everything the reader would need as they begin their study of the nervous system. At the same time the experienced neuroscientist will find much useful and valuable information in these pages that is based almost exclusively on studies in experimental primates and observations in humans. Every effort has been made to present the complexities of the nervous system as simply and clearly as possible. The careful reader will discover a clarity and depth of coverage that makes the reading both instructional and enjoyable. Topics are presented logically and the text in an easy-to-read style. The accompanying line drawings emphasize important concepts in a clear and uncluttered manner. Topics presented: Neurons, glial cells, degeneration, regeneration, axonal transport Review of the development of the human nervous system Overview of the anatomy of the spinal cord, brain stem and forebrain General sensory paths (pain, temperature, touch, pressure, proprioception) Special sensory systems (auditory, vestibular, visual, olfactory and gustatory) Eye movements and visual reflexes Comprehensive presentation of the regions involved in motor activity including the clinical manifestation of injuries to these motor areas Limbic system, hypothalamus and the autonomic nervous system Lobes of the brain, clinically important cortical areas and the results of lesions in these areas Blood supply to the spinal cord, brain stem, and brain including classical brain stem syndromes The meninges and the ventricular system Numerous helpful clinical correlations that emphasize the practical application of basic anatomical information Presents the complexities of the nervous system as simply and clearly as possible Written with a clarity and depth of coverage that makes the reading both instructional and enjoyable Includes numerous illustrations emphasizing important concepts

Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behavior and aging. This book based on contributions of pioneer investigators in the field, outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Degeneration of sensory receptors or of the nerves innervating them leads to a sensory deficit. Various strategies have been tried for promoting regrowth of sensory receptors, particularly in the eye and ear. The latest data from experimental studies in animals are presented in the book including applications of BDNF and CNTF in the eye and epidermal growth factor in the ear.

'As in his earlier books, Professor Siegel documents his textual material thoroughly, and includes plentiful translated passages, many appearing here for the first time in English... The book is full of most interesting and useful data.'Medical History