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This book pushes the limits of conventional MRI visualization methods by completely changing the medical imaging landscape and leads to innovations that will help patients and healthcare providers alike. It enhances the capabilities of MRI anatomical visualization to a level that has never before been possible for researchers and clinicians. The computational and digital algorithms developed can enable a more thorough understanding of the intricate structures found within the human body, surpassing the constraints of traditional 2D methods. The Physics-informed Neural Networks as presented can enhance three-dimensional rendering for deeper understanding of the spatial relationships and subtle abnormalities of anatomical features and sets the stage for upcoming advancements that could impact a wider range of digital heath modalities. This book opens the door to ultra-powerful digital molecular MRI powered by quantum computing that can perform calculations that would take supercomputers millions of years.

This book offers a comprehensive overview of the use of breast MRI for screening high-risk women, including those with familial-genetic hereditary predisposition and previous chest radiation therapy, typically lymphoma survivors. It discusses the historical background of studies and research that provided the body of evidence in favor of MRI screening of these women. Technical and clinical topics are treated in dedicated chapters, including models for individualized risk estimation, radiogenomics of breast cancer in high-risk women, computer-aided detection/diagnosis and machine learning systems applied to breast MRI, and psycho-oncology issues. Alternatives to breast MRI screening such as pharmaco-prevention and prophylactic mastectomy are also discussed, taking into account the public debate on the “Angelina Jolie” effect. The high breast cancer risk model is proposed as a paradigm for personalized medicine. This book will be of interest to radiologists, surgeons, oncologists and to all professionals devoted to female healthcare.

This book provides, for the first time, a unified approach to the application of MRI in radiotherapy that incorporates both a physics and a clinical perspective. Readers will find detailed information and guidance on the role of MRI in all aspects of treatment, from dose planning, with or without CT, through to response assessment. Extensive coverage is devoted to the latest technological developments and emerging options. These include hybrid MRI treatment systems, such as MRI-Linac and proton-guided systems, which are ushering in an era of real-time MRI guidance. The past decade has witnessed an unprecedented rise in the use of MRI in the radiation treatment of cancer. The development of highly conformal dose delivery techniques has led to a growing need to harness advanced imaging for patient treatment. With its flexible soft tissue contrast and ability to acquire functional information, MRI offers advantages at all stages of treatment. In documenting the state of the art in thefield, this book will be of value to a wide range of professionals. The authors are international experts drawn from the scientific committee of the 2017 MR in RT symposium and the faculty of the ESTRO teaching course on imaging for physicists.

This atlas provides a comprehensive, state of the art review of the use of multiparametric MRI (mpMRI) for the imaging of prostate cancer, covering aspects from diagnosis and loco-regional staging through to the role of the technique after treatment and follow-up. The book contains a wealth of high-resolution images, many of them in color, and displays the anatomical-MRI–pathological correlation whenever appropriate. Readers will find a helpful overview on the current standardized method for reading and reporting on mpMRI, the Prostate Imaging Reporting and Data System (PI-RADS), version 2. Dedicated chapters focus on differential diagnosis and imaging pitfalls, and the inclusion of helpful diagrams and algorithms will further assist in image interpretation, enabling readers to ease and improve their use of mpMRI. Edited and written by very experienced radiologists, pathologists, and urologists; the Atlas of Multiparametric Prostate MRI will serve as a unique source of clinically relevant information and an aid to disease management for radiologists, urologists, pathologists, radiotherapists, and oncologists.

In this book, experts from premier institutions across the world with extensive experience in the field clearly and succinctly describe the current and anticipated uses of PET/MRI in oncology. The book also includes detailed presentations of the MRI and PET technologies as they apply to the combined PET/MRI scanners. The applications of PET/MRI in a wide range of oncological settings are well documented, highlighting characteristic findings, advantages of this dual-modality technique, and pitfalls. Whole-body PET/MRI applications and pediatric oncology are discussed separately. In addition, information is provided on PET technology designs and MR hardware for PET/MRI, MR pulse sequences and contrast agents, attenuation and motion correction, the reliability of standardized uptake value measurements, and safety considerations. The balanced presentation of clinical topics and technical aspects will ensure that the book is of wide appeal. It will serve as a reference for specialists innuclear medicine and radiology and oncologists and will also be of interest for residents in these fields and technologists.

This book presents up to date debates and issues in the world of breast MRI with a very practical focus on how to incorporate current understanding of breast MRI into clinical practice. The book is divided into three key sections, all of which have critical impact for the breast imager: Techniques introduces the reader to the parameters of breast MRI from standard sequences to up-to-date cutting edge techniques. Indications provides a careful review of the accepted indications for breast MRI from High Risk Screening to use of breast MRI, in the context of neoadjuvant chemotherapy with a detailed analysis of the evidence-based support for these indications and a careful look at controversies and debates within the field. MRI Findings, Interpretation, and Management takes on the topics of how to interpret and manage specific MRI findings from benign to malignant disease with a focus on radiologic-pathologic correlation. The section also incorporates a focus on key management dilemmas, including appropriate follow-up intervals for benign findings on MRI and management of probably benign lesions assessed as a Breast Imaging Reporting and Dictating System (BI-RADS)-3 category on MRI.

This atlas serves as a basic introduction to breast MRI. Organized by case, it emphasizes pertinent breast MRI findings and common indications for breast MRI. Topics include breast MRI basics, benign findings, breast malignancy, high-risk conditions, interesting cases, and breast implants. Brief teaching points accompany each case and highlight the importance of the findings. Breast MRI Teaching Atlas is an ideal resource for diagnostic radiologists, residents, fellows, and clinicians involved in the care of breast cancer patients, including surgeons, oncologists, and obstetricians/gynecologists.

This book helps readers to overcome the challenges encountered during the imaging diagnosis of soft tissue tumors due to their diversity and the significant overlap in imaging features between different tumors. It does so by fostering familiarization with typical findings and clearly explaining the pattern analysis of soft tissue tumors. The book opens with an overview of diagnostic considerations and discussion of the basic concepts of diagnostic imaging studies and histopathologic examinations. Grading and staging of soft tissue sarcomasare then described.In the second part of the book, radiologic features of soft tissue tumors are reviewed in detail, based on the 2013 WHO classification system.The third part summarizes diagnostic imaging clues, including characteristic imaging findings and radiologic signs that aid in specific diagnosis and differential diagnosis. The book closes by presenting 30 typical cases of soft tissue tumors, with questions, answers, and commentary, in orderto help readers to consolidate what they have learned and to hone their diagnostic reasoning skills.

Effectively perform and interpret MR body imaging with this concise, highly illustrated resource! Fundamentals of Body MRI, 2nd Edition, by Drs. Christopher Roth and Sandeep Deshmukh, covers the essential concepts residents, fellows, and practitioners need to know, laying a solid foundation for understanding the basics and making accurate diagnoses. This easy-to-use title in the Fundamentals of Radiology series covers all common body MR imaging indications and conditions, while providing new content on physics and noninterpretive skills with an emphasis on quality and safety. - More than 1,400 detailed MRI images and 100 algorithms and diagrams highlight key findings and help you grasp visual nuances of images you're likely to encounter. - All common body MR imaging content is covered, along with discussion of how physics, techniques, hardware, and artifacts affect results. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Newly streamlined format helps you retrieve important information more quickly. - Extensively revised content on the liver, including new MRI contrast agents; new coverage of the spleen; and new safety tips and guidelines keep you up to date. - New chapters on GI imaging, the prostate, and the male genitourinary system make this a one-stop reference to address the full range of body MRI.

Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990's, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer's disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource. - Presents the most comprehensive, relevant, and accurate information on HP gas MRI - Co-edited by the co-inventor of HP gas MRI, Dr. Albert, with chapter authors who are the leading experts in their respective sub-disciplines - Serves as a foundation of understanding of HP gas MRI for researchers and clinicians involved in research, technology development, and clinical use with HP gas MRI - Covers all hyperpolarized gases, including helium, the gas with which the majority of HP gas MRI has been conducted

This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the purposes of diagnosis and treatment. Simultaneous evaluation of anatomic and metabolic information about normal and abnormal processes addresses complex clinical questions and raises the level of confidence of the scan interpretation. Extensively illustrated with high-resolution PET/MRI, PET/CT and SPECT/CT images, this atlas provides precise morphologic information for the whole body as well as for specific regions such as the head and neck, abdomen, and musculoskeletal system. Atlas and Anatomy of PET/MRI, PET/CT, AND SPECT/CT is a unique resource for physicians and residents in nuclear medicine, radiology, oncology, neurology, and cardiology.

This practically oriented book opens by describing the basic Cardiac MR (CMR) sequences and Cardiac CT (CCT) acquisition techniques, offering step-by-step guidelines on acquiring CMR and CCT studies and analyzing images. The main body of the book provides a comprehensive description of the study protocols most suitable for particular diseases and discusses their respective rationales. In addition, it highlights key findings for every pathological condition, complemented by extensive illustrations. The book especially addresses the needs of junior cardiologists and radiologists embarking on the regular use of MR-based and CT-based cardiac imaging, though it also offers a valuable reference manual for senior specialists. Of particular benefit is the inclusion of both CMR and CCT, techniques which are usually treated separately, despite the regular use of both at advanced Cardiac Imaging Units.

MRI provides the best means of imaging the bone marrow directly and of non-invasively assessing its composition. Normal age-related bone marrow changes, alterations related to red marrow reconversion, and pathological bone marrow processes generally conform to certain patterns that reflect the underlying marrow changes and can be clearly recognized on MR images. In addition to conventional pulse sequences, advanced MRI techniques such as Dynamic Contrast-Enhanced MRI and Diffusion-Weighted Imaging depict marrow changes at the microvascular and cellular level respectively. This book provides radiologists with in-depth information on the MRI appearances of normal, abnormal and treated marrow following a structured, pattern-based approach. MRI findings for various diseases that affect the bone marrow, particularly those of a malignant nature, are presented in detail. MRI pattern recognition not only offers a systematic approach to image interpretation and diagnosis but also has prognostic implications with regard to some disease entities. Each chapter includes a wealth of high-quality images, together with Key Points summarizing the most important information. In addition to radiologists, practitioners with an interest in hematology and oncology will find this textbook-atlas to be a valuable resource for the latest, clinically relevant advances in bone marrow imaging.

This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Imaging of Brain Tumors is a unique resource that serves to advance patient care and research in this rapidly developing field.

This new project on PET-MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad.The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments.The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images.The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.

This atlas is a detailed guide to the imaging appearances of gliomas following treatment with neurosurgery, radiation therapy, and chemotherapy. Normal and pathological findings are displayed in detailed MR images that illustrate the potential modifications due to treatment. Particular emphasis is placed on characteristic appearances on the newer functional MR imaging techniques, including MR spectroscopy, diffusion-weighted imaging, and perfusion imaging. These techniques are revolutionizing neuroradiology by going beyond the demonstration of macroscopic alterations to the depiction of preceding metabolic changes at the cellular and subcellular level, thereby allowing earlier and more specific diagnosis. A key section comprising some 40 clinical cases and more than 500 illustrations offers an invaluable clinical and research tool not only for neuroradiologists but also for neurosurgeons, radiotherapists, and medical oncologists.

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.The introductory part of the book c

Carcinoma of the urinary bladder is a common (in the USA it is the fifth most common form of cancer in males and tenth most common form of cancer in females) malignan­ cy and one in which noninvasive staging by imaging plays such an important role. This book presents a complete approach to MR imaging of carcinoma of the urinary bladder from a detailed discussion of the value of MRI in the diagnosis of the urinary bladder to the history of the procedure. The technical discussion of the general principles of MRI including the optimal pulse sequences to be used and factors that influence the quality of images are included in this book. The safety factors are also presented along with contraindications. The application of a double surface coil with the field strength of O.5T provides the fine quality of the illustrations. The atlas of comparative anatomy by MRI on normal volunteers and post-mo'rtem specimens as well as MR images on patients with bladder tumors and post-surgery specimens is unique. The results of the clinical imaging stu­ dies in patients with carcinoma of the bladder, comparing the relative value of clinical staging, MR, CT and lymphography, are helpful in showing the advantages of MRI.

This book describes the current status of the very rapidly developing field of high-field MR and examines the possibilities, challenges, and limitations of this fascinating technology. In the initial chapters, the basic technological background is explained in a non-technical way so as to promote understanding of the issues and concepts and avoid overwhelming the reader with excessive detail. Safety issues, methods, and contrast are then carefully considered. The final part of the book examines the diverse applications of high-field MR imaging in radiology, neuroscience, oncology, and other fields, with the aid of numerous high-quality illustrations. All chapters are written by leading experts who have taken great care to illustrate the potential and progress of the field in an informative and accessible manner. The book will appeal to all with a potential interest in the application of high-field MR imaging, including radiologists, neuroscientists, and oncologists.

This volume provides a deeper understanding of the diagnosis of brain tumors by correlating radiographic imaging features with the underlying pathological abnormalities. All modern imaging modalities are used to complete a diagnostic overview of brain tumors with emphasis on recent advances in diagnostic neuroradiology. High-quality illustrations depicting common and uncommon imaging characteristics of a wide range of brain tumors are presented and analysed, drawing attention to the ways in which these characteristics reflect different aspects of pathology. Important theoretical considerations are also discussed. Since the first edition, chapters have been revised and updated and new material has been added, including detailed information on the clinical application of functional MRI and diffusion tensor imaging. Radiologists and other clinicians interested in the current diagnostic approach to brain tumors will find this book to be an invaluable and enlightening clinical tool.

It is a great privilege to introduce this book devoted to the current and future roles in research and clinical practice of another exciting new development in MRI: Diffusi- weighted MR imaging. This new, quick and non-invasive technique, which requires no contrast media or i- izing radiation, offers great potential for the detection and characterization of disease in the body as well as for the assessment of tumour response to therapy. Indeed, whereas DW-MRI is already? rmly established for the study of the brain, progress in MR techn- ogy has only recently enabled its successful application in the body. Although the main focus of this book is on the role of DW-MRI in patients with malignant tumours, n- oncological emerging applications in other conditions are also discussed. The editors of this volume, Dr. D. M. Koh and Prof. H. Thoeny, are internationally well known for their pioneering work in the? eld and their original contributions to the l- erature on DW-MRI of the body. I am very much indebted to them for the enthusiasm and engagement with which they prepared and edited this splendid volume in a record short time for our series Medical Radiology – Diagnostic section.

MRI Atlas of Prostate Cancer analyses high-resolution MRI scanning and dynamic contrast-enhanced (DCE) MRI. This combination improves the diagnosis and staging of prostate cancer and may soon replace PSA testing and digital rectal examination. The first two chapters focus on normal anatomy, anatomic variations, benign disease and intraprostatic tumors. The subsequent chapters on MRI of extracapsular disease create a useful atlas of pathologic anatomy. This is the first text of its kind to show color-coded DCE-MRI scans of prostate cancer and to correlate these imaging findings with tumor grading. The chapters on the post-treatment prostate clearly display the increasing incidence of post-therapy recurrences. This book is intended for internists, radiologists, radiotherapists, oncologists, urologists, family practitioners, and general surgeons. Ultrasound, MRI, and radiotherapy technicians will find it extremely useful as a reference guide.

MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical tr

Imaging in Oncology will serve as an up-to-date, attractive book of oncologic imaging for radiologists, oncologists, radiation therapists and others involved in oncologic care. This volume provides pertinent clinical and research information that underpins accurate interpretation and sensible use of cancer imaging. It reviews the role of established and upcoming techniques in plain radiography, ultrasound, CT, MR nuclear medicine, PET and PET/CT for oncologic imaging as well as image-guided intervention. The book also highlights new developments and advances in oncologic imaging. Imaging in Oncology will appeal to physicians in practice and in training and to all interested in oncologic imaging.

Breast cancer is the leading cause of cancer-related deaths in women, and its incidence and prevalence have been steadily rising in recent decades. This book describes morphologic and kinetic signs that are important in the analysis of breast MR images before and after contrast administration and in various pulse sequences. Earlier this method was regarded as high sensitive but low specific. Today, by utilizing all the information contained in MR data sets, we can greatly increase the specificity of MRM. This gives MRM a very high overall accuracy in the diagnosis and differential diagnosis of breast lesions, making it possible to detect cancers as small as 3 mm with a high degree of confidence. This book is intended to help broaden and expedite the clinical application of MRM so that as many physicians as possible can make more accurate and confident diagnoses.

This highly illustrated book provides practical and pragmatic guidance in breast MRI for all professionals involved in breast imaging or the care of patients with breast diseases.

Title from ebook title screen (viewed on Mar. 23, 2005.)

In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on'Developing Technologies for Early Breast Cancer Detection'was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.