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Gallbladder Cancer: A Comprehensive Guide to Management was planned as a thorough, yet objective text about gallbladder cancer, encompassing from epidemiology and pathogenesis to the present cutting edge technology and ongoing research. This work provides a comprehensive review of a worldwide scope disease as a collaboration of renowned researchers from different continents, including the latest discussions of crucial topics on gallbladder cancer management. The epidemiology content covers epidemiologic data, trends over time, risk factors, incidence and cancer specific mortality rates. Chapters describe the intrinsic molecular mechanisms of oncogenesis associated with the pathogenetic mechanisms, genomics, proteomics and transcriptomics. Regarding prevention, prophylactic measures and preventive use of drugs is presented. Chapters also describe the clinical, radiological, laboratorial aspects of the different forms of gallbladder cancer. In addition, the role of biomarkers for diagnosis, prognosis and follow up is explored. Readers will also find topics such as management through multidisciplinary treatment, surgical controversies, systemic therapy and radiation therapy. The book is a valuable resource to general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents.

This book is designed to present a practical and evidence-based approach to liver and pancreas surgery that will provide both experienced and novice surgeons as well as surgical trainees a resource for optimizing their outcomes. The entire perioperative spectrum of care is addressed in chapters written by an international panel of experts in the field. Initial sections discuss preoperative assessment and intervention, fluid management, and perioperative pain control. Subsequent chapters focus on the specific aspects of operative approach and technique, including minimally invasive surgery, fluid management, parenchymal transection, and use of drains, tubes and stents. The text concludes with chapters on perioperative pain control, management of complications as well as the role of enhanced recovery pathways. A brief review of the existing literature addressing the particular topic follows in each section. Extensive illustrations, figures, and tables provide reinforcement to the educational content. Optimizing Outcomes for Liver and Pancreas Surgery will provide readers an easy to reference guide with easily accessible text and visual aids.