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Perfect for introductory level students, Hole's Human Anatomy and Physiology is crafted to be easily understood, even for those without a science background. The book prioritizes building a solid foundation by exploring essential themes distilled into fundamental concepts and highlighting underlying mechanisms. The content is presented in an easy to digest writing style, complemented by striking artwork and illustrations. Throughout the text, the Learn, Practice, Assess method is consistently applied, seamlessly integrating assessment and practice opportunities. This approach assists students in honing their understanding and concentrating their study efforts. The author team, actively engaged in the classroom, brings a blend of career relevance, an emphasis on clinical applications, concise language, and a contemporary perspective to this esteemed anatomy and physiology classic.

This is a fully revised Second Edition of a well-structured textbook that offers essential knowledge on the vascular system. The reader will learn the properties, basic cellular mechanisms, and development of the different parts of the vascular system (including the heart and lung), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, animal models, and ex vivo. This book is based on a Ph.D. Course for students from various scientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master´s Students in vascular biology and biomedicine in general and a helpful tool for young researchers worldwide wishing to gain or refresh their knowledge in this field.

This edited volumeaims to describe physiological and pathophysiological mechanisms that underlie human maternal-fetal interactions. The book emphasizes the structure and development of the fetoplacental unit, the endocrine and nutritional regulation of fetal development, nitric oxide signalling, solute carriers function and ion channels regulation in healthy pregnancies and diseases, like preeclampsia, gestational diabetes, and maternal obesity, among others. Also, we highlight novel mechanisms associated with language impairment in children, the use of serotonin inhibitors or cannabis during pregnancy, and maternal conditions'potential impact on cerebrovascular development in newborns and infants. The cellular and molecular understanding of maternal-fetal physiology and pathophysiology will allow the readers to understand the impact of diseases or conditions that are highly prevalent in pregnant women.

The book will contain reviews and brief research articles from the participants attending the International Society for Arterial Chemoreception (ISAC) meeting, to be held in Lisbon in Portugal in June/July 2020. Since ISAC was first established, almost 70 years ago, many advances in the classical field of arterial O2, CO2 and pH sensing have been achieved but the most impressive ones are probably related to the non-canonical roles of the carotid body, as its involvement in sympatho-mediated diseases. Over the recent years, the carotid body field has gained attention with the findings that carotid body dysfunction is associated with the development/maintenance of highly prevalent diseases from cardio-metabolic diseases to asthma. Knowing that most of the patients with these pathologies lack long-term disease control, it is imperative to define new pathophysiological mechanisms aiming to find new therapeutic targets for treatment and prevention. This book will cover a broad range of topics related, not only with the fundamental knowledge of the mechanisms related with the chemical sensing in the carotid body, but also with the adaptive and mal-adaptive responses of arterial chemoreceptors to O2-dependent and O2-independent mechanisms, namely with their impact on respiratory, cardiovascular, and metabolic homeostasis in healthy and disease conditions. This volume will be required text for all the researchers in the field of arterial chemoreceptors and will provide a valuable reference source for years to come.

This book entitled'Nitric Oxide: From Research to Therapeutics'includes the most recent information about the role of Nitric Oxide (NO) in physiology, pathophysiology and its translation to therapeutics. The Editors are vastly experienced in the field of NO research. The international panels of contributors to the various chapters of the book are all well-established researchers and health professionals who have worked in different areas of NO physiology and pathophysiology, and have made a considerable impact in the field. The book is a comprehensive collection of the most recent information on NO as a physiological regulator and its diverse potential as a therapeutic target for the treatment for a variety of disease states. This compilation is aimed at professionals and students from both academia and the industry in the areas of basic biomedical and clinical sciences.

The fascinating area of molecular medicine provides a molecular and cellular description of health and disease. Starting with the understanding of gene regulation and epigenetics, i.e., the interplay of transcription factors and chromatin, this book will provide an fundamental basis of nearly all processes in physiology, both in health as well as in most common disorders, such as cancer, diabetes as well as in autoimmune diseases. Most non-communicable human diseases have a genetic (= inherited) as well as an epigenetic component. The later one is based on our lifestyle choices and environmental exposures. Many common diseases, such as type 2 diabetes, can be explained only to some 20% via a genetic predisposition. We cannot change the genes that we are born with but we can take care of the remaining 80% being primarily based on our epigenome. Therefore, there is a high level of individual responsibility for staying healthy. Thus, not only biologists and biochemists should be aware of this topic, but all students of biomedical disciplines will benefit from being introduced into the concepts of molecular medicine. This will provide them with a good basis for their specialized disciplines of modern life science research. The book is subdivided into 42 chapters that are linked to a series of lecture courses in “Molecular Medicine and Genetics”, “Molecular Immunology”, “Cancer Biology” and “Nutrigenomics” that is given by one of us (C. Carlberg) in different forms since 2002 at the University of Eastern Finland in Kuopio. This book represents an updated version and fusion of the books textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8). “Molecular Immunology: How Science Works” (ISBN 978-3-031-04024-5), “Cancer Biology: How Science Works” (ISBN 978-3-030-75699-4) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4). By combining basic understanding of cellular mechanism with clinical examples, the authors hope to make this textbook a personal experience. A glossary in the appendix will explain the major specialist's terms.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.​

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.​

This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importancefor maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.

Designed for the one-semester A&P course, Seeley's Essentials of Anatomy & Physiology is designed to help students develop a solid, basic understanding of essential concepts in anatomy and physiology. Critically important information is presented in a way that maximizes understanding. With an emphasis on critical thinking, students build a knowledge base for solving problems. Clinical Impact features throughout the text bring relevance to the reader, while instructive artwork promotes interest and clarifies ideas.

Dieses Buch bietet einen Überblick über die Kryobiologie, einen Teilbereich der biomedizinischen Forschung, der sich seit vielen Jahren mit der Lebenserhaltung durch Kälte beschäftigt. Zum Beispiel werden Zellkulturen und winzige Gewebeproben bei kryogenen Temperaturen (unter etwa -90°C) aufbewahrt. Eine Wiederbelebung von Organen ist bisher fast ausschließlich nach einer Kühlung auf Temperaturen von 0 bis -80°C gelungen und heute noch Gegenstand der Forschung. Der aktuelle Forschungsstand wird hier zusammengefasst und für verschiedene Tierarten und konkrete Anwendungsbereiche dargelegt. Vor allem wird auf große biologische Einheiten, wie z. B. menschliche Organe und, als Fernziel, den ganzen menschlichen Organismus, eingegangen. Es werden die Notwendigkeit sowie die Möglichkeiten für die Vermeidung von Eiskristallen und Stressfrakturen während der Kühlung auf kryogene Temperaturen erklärt, um eine sichere Lagerung zu ermöglichen.Neuere Methoden werden vorgestellt,die versuchen mit geringstmöglichen Konzentrationen von Frostschutzmitteln auszukommen, da diese Nebenwirkungen verursachen aber benötigt werden, um die Kristallisierung, wie auch die Stressfrakturen geringzuhalten.Dieses Buch richtet sich an Personen, die sich über das Feld der Kryobiologie informieren möchten und dessen Fortschritte, Einsatzmöglichkeiten, aber auch die momentanen Limitierungen kennen lernen möchten.

This is the first textbook solely dedicated to the study of exocrine glands and cells throughout the human body. Students will gain a broad overview of the whole exocrine system, it's structural features and learn to understand it's integral parts in almost all bodily functions. Taking a systemic approach, the author guides readers through the different organ sites, shapes, methods of secretion and their secretory products. Starting with the glands of the integument, which is covering the outside of the body, the chapters proceed to also discuss the urinary tract, respiratory, digestive and reproductive systems. Various levels of complexity, from single goblet cells to the major organs, are thoroughly explained. A basic knowledge in histology is advantageous, for the numerous and rich illustrations. With its inviting writing style, this textbook is a perfect learning tool for students in Physiology and Medicine – particularly considering Dentistry, Dermatology, Gastroenterology and Pulmonology.

This third and final volume in the'Ion Transport in Tumor Biology'collection presents novel diagnostic and therapeutic approaches in cancer based on the exploitation of ion transport proteins. The authors critically examine several transportome members, particularly Na+, K+, Ca2+, and Cl- channels, as well as organic solute carriers regarding their suitability as therapeutic targets. Synergistic effects resulting from the combined use of classical cytostatics with ion transport-inhibiting drugs are pointed out, and the capability of bispecific antibodies to function as anticancer drugs is discussed. As readers will also learn, the use of ion channel inhibitors could improve the outcome of radiotherapy because the development of radio-resistance during radiotherapeutic treatment often correlates with increases in the expression levels and conductance of ion channels. The translational topics of this volume form a bridge between biochemical research and therapeutic application. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians in the cancer field.

This is the first of three volumes in the'Ion Channels & Transporters in Tumor Biology'collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis. The authors highlight the role of the so-called transportome, which is defined by the entirety of ion transporters and ion channels. Thereby, readers will get a better understanding of the impact dysregulated ion transport has on the whole spectrum of cancer types. Cancers display deficiencies in several, sometimes interdependent members of the transportome.Clinicians will be interested in the fact that controlled expression of ion transport proteins dramatically impacts the life span of cancer patients, as shown in recent studies. These observations offer a promising outlook for biomedical scientists, as members of the transportome could be the tumor markers of tomorrow - both for diagnostic and therapeutic purposes.As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians from the cancer field.

This comprehensive Monograph examines all peripheral and central mechanisms of regulating the secretion of milk from the lactating breast. The author reviews the complete female breast development, starting with the early childhood, up to pregnancy and lactation. Structural and ultrastructural data on the alveolar-ductal system, together with details of breast innervation, are used to investigate the physiological process of lactation. Readers will appreciate the special focus on reflexes, both in the child and the mother, that help to regulate maternal milk production and secretion. Following this, the author sheds a light on the composition and dynamics of milk components during the different periods of lactation. The final section of this volume focusses on practical aspects of modern breastfeeding, like the use of breast pumps or galactogogues, to influence the productivity of milk production. These fundamental principles and structural details will be particularly useful for physiologists and clinicians working in gynecology and pediatrics.

This book integrates topics in basic research and clinical medicine as well as molecular and cell biology.It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric oxygen treatment for COVID-19. A comprehensive insight is offered into the unresolved molecular pathways in chemosensing that plays a vital role in detecting insufficient tissue oxygenation, as well as in sporting accomplishments. Other articles address cardiorespiratory and humoral responses to hypoxia, the function of cementum in the repair and regeneration of teeth, and periprosthetic fractures following hip arthroplasty in the elderly. The issue of the overwhelming burdens on caregivers to spinal injury patients, damaging both health and psychosocial status, is addressed.The book promotes translation of scientific advances to the general medical practice. It will be a valuable reference for clinical healthcare professionals and researchers interested in innovative practices to improve the prevention, diagnosis, and management of diseases.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.​

This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.

Essentials of Human Anatomy & Physiology helps learners focus on the essentials of A&P, without getting sidetracked in unnecessary details. The brief and accessible text combines short, easy-to-read chapters with easy-to-follow figures to provide a near-perfect level and depth of content needed for success in the one-semester A&P course.

So wie die Feuerwehr nicht schuld ist am verheerenden Großbrand, so ist unser Fettgewebe nicht schuld an Diabetes und Herzinfarkt. Nur wenn wir unser Fettgewebe verstehen, können wir sein Potenzial erhalten und nutzen. Petra Schling gibt in diesem essential einen Überblick über Aufbau und Funktionen unseres Fettgewebes und stellt die wichtigsten Botenstoffe von Fettzellen und ihren Vorläufen vor. Darüber hinaus klärt die Autorin Irrtümer und Missverständnisse auf, die sich um das Fettgewebe ranken. Sie erläutert eine mögliche Kausalkette vom Überfluss zum Diabetes und warum das Fettgewebe zu Unrecht zum Sündenbock gemacht wird.

This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.

This second volume of Defining Physiology: Principles, Themes, Concepts. continues on the same format as the first.In this new release, a selection of 44 essential topics in each major organ system is defined, then major themes, concept and principles surrounding these words in their physiologic scenarios are elaborated. For each keyword, a question is posed at the end of the text to test for a better understanding of the associated physiology of nervous and gastrointestinal systems.This book presents an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.

This contributed volume emphasizes the potential of stem cells to be pertained in the urology field and attempts to disclose the history of the field up to the latest advances to date. It gathers the majority of papers that advocate utilizing stem cells as the best option for treating, diagnosing, and managing diseases related to urological system. This book covers a broad spectrum of issues, including mesenchymal stem cells, cancer stem cells, organoids, regenerative medicine, erectile dysfunction, bladder dysfunction, and kidney transplant. From several decades ago, as characteristic features of stem cells have been explored, it has attracted a great amount of interests. In view of their multiple capacity of differentiating into various lineages, many studies were conducted to assess their beneficial potential. Despite considerable progress into applying stem cells in animal models, for translating into clinical practices there are several obstacles to be resolved. However, few clinical studies have been performed in each field and outcomes were delightful. There is an ongoing hope for stem cells to someday, be the mainstream treatments of urological diseases, although stem cells treatments already exist they are not well-known. Indeed, this book is essential for anyone who is working with the purpose of employing stem cells to treat the urological diseases and discusses at length the latest advances as well as their limitations.

Anatomy, Physiology, and Disease ISE

For two-semester courses in anatomy & physiology. A streamlined option to equip students for success in A&P and beyond Anatomy & Physiology, 7th Edition answers the demand for a leaner version of Elaine Marieb and Katja Hoehn's best-selling Human Anatomy & Physiology while maintaining the trusted, accurate, and carefully-paced approach of the more comprehensive 11th Edition. A total of 26 abridged chapters focus on core concepts and allow instructors to expand on broader topics such as pregnancy, development, and genetics outside of reading assignments from the text. The 7th Edition motivates and supports learners at every level, from novice to expert, equipping them with 21st century skills to succeed in A&P and beyond. Hallmark Focus Figures and an expanded number of summary tables and in-line figures help learners practice and develop visual literacy skills. A greater variety and range of self-assessment questions guide students in advancing from mastering A&P terminology to applying knowledge in clinical scenarios and performing the critical thinking and problem-solving skills required for entry to nursing, allied health, and exercise science programs. Also available with Mastering A&P By combining trusted author content with digital tools and a flexible platform, Mastering personalizes the learning experience and improves results for each student.Mastering personalizes learning and improves results for each student. Built for, and directly tied to the text, Mastering A&P enables an extension of learning, allowing students a platform to practice, learn, and apply outside of the classroom. Note: You are purchasing a standalone product; Mastering A&P does not come packaged with this content. Students, if interested in purchasing this title with Mastering A&P, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering A&P search for: 0135205050 / 9780135205051 Anatomy & Physiology Plus Mastering A&P with Pearson eText -- Access Card Package Package consists of: 013516804X / 9780135168042 Anatomy & Physiology 0135202094 / 9780135202098 Mastering A&P with Pearson eText -- ValuePack Access Card -- for Anatomy & Physiology

The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology

Unsere Sinne - Sehen, Hören, Riechen, Schmecken und Tasten - bestimmen wesentlich unser Leben. Alles was wir wissen, wurde uns von unseren Sinnen vermittelt. Aber wie funktionieren unsere Sinne und wie kommt das Wissen über die Welt in unseren Kopf? Nach welchen Kriterien entscheidet unser Gehirn, was zu tun ist?In diesem Sachbuch wird allgemeinverständlich dargelegt, wie hoch entwickelt die Sinnesorgane bei Tieren und Menschen sind. Oft erreichen Sinnesleistungen die Grenze des physikalisch Möglichen. Das Buch erklärt, wie Sinnesreize erfasst werden, wie sie in die Sprache des Nervensystems übersetzt werden und wie unser Gehirn Sinnesinformation verarbeitet. Das Gehirn setzt dabei auf wohl bewährte Strategien, die ein Ziel verfolgen: die Überlebenschance des Organismus zu erhöhen. Deshalb wird in diesem Buch gezeigt, wie sehr die Sinnesleistungen durch die Evolution geformt und bestimmt wurden. Das Buch zeigt auch, dass viele Tiere ihre Umwelt vollkommen anders wahrnehmen als wir.Für die Neuauflage haben die Autoren den Text durchgesehen und auf den aktuellen Stand gebracht.

This book takes readers on a journey around the world and through time, accompanied by a modern neurosurgeon who reviews historical techniques and instruments used for cranial opening. The author draws on original medical and surgical books to provide a comprehensive history of these techniques and tools. To complement the general overview and offer readers a more ‘hands-on'sense of context and atmosphere, extensive historical references, stories, media news and illustrative cases have been included for each historical and geographical scenario. In addition, original illustrations and plates of these archaic instruments and techniques are supplied. Neurosurgical surgeons, nurses, technicians, medical historiographers, paleo-pathologists and researchers interested in surgical techniques for cranial opening will find the volume a valuable guide, intended to increase the historical and cultural awareness of this core topic in neurological surgery.

Ein Lehrbuch für Ärzte in Weiterbildung für das Fach Neurologie, das die pathophysiologischen und die biochemischen Ursachen und Komplikationen neurologischer Erkrankungen verständlich darstellt und sinnvoll in den klinischen Gesamtzusammenhang einordnet. Im Medizinstudium wird die genaue Kenntnis der Neuroanatomie als Grundlage für klinisch-neurologische Diagnostik und Therapie gelehrt. In der klinischen Praxis ist es jedoch relevant, neben dem neurologisch-topischen Wissen auch die pathophysiologischen Grundlagen zu begreifen, um daraus adäquate therapeutische Schritte ableiten zu können. Die Fülle theoretischer Grundlagen erschwert es sowohl Berufsanfängern als auch Studierenden, den Überblick zu behalten. Genau diese Lücke füllt das vorliegende Buch.

This textbook helps you to prepare for both your next exams and practical courses by combining theory with virtual lab simulations. With the “Labster Virtual Lab Experiments” book series you have the unique opportunity to apply your newly acquired knowledge in an interactive learning game that simulates common laboratory experiments. Try out different techniques and work with machines that you otherwise wouldn't have access to.In this volume on “Basic Biology” you will learn how to work in a biological laboratory and the fundamental theoretical concepts of the following topics:Lab SafetyMitosisMeiosisCellular RespirationProtein SynthesisIn each chapter, you will be introduced to the basic knowledge as well as one virtual lab simulation with a true-to-life challenge. Following a theory section, you will be able to play the corresponding simulation. Each simulation includes quiz questions to reinforce your understanding of the covered topics. 3D animations will show you molecular processes not otherwise visible to the human eye.If you have purchased a printed copy of this book, you get free access to five simulations for the duration of six months. If you're using the e-book version, you can sign up and buy access to the simulations at www.labster.com/springer.If you like this book, try out other topics in this series, including “Basic Genetcis”, “Basic Biochemistry”, and “Genetics of Human Diseases”.Please note that the simulations included in the book are not virtual reality (VR) but 2D virtual experiments.

Human Anatomy & Physiology helps you develop critical thinking and problem-solving skills required for entry to nursing, allied health and exercise science programs. Best-selling authors Elaine Marieb and Katja Hoehn help to provide support and motivation for all levels, from beginner to expert, equipping you with 21st-Century skills to succeed in A&P and beyond. Each chapter guides you from A&P terminology to applying knowledge in clinical scenarios, to practicing the critical thinking and problem-solving skills. Recognized for its engaging, conversational writing style, easy-to-follow figures, and its unique clinical insights, Human Anatomy & Physiology, continues the tradition of innovation and addressing the most effective ways to learn.

This book provides accurate, comprehensive, and convenient reference for usages of the “freely rotatable three dimensional combined Nissl-stained and MRI digital data of the marmoset brain”. The key features of the original 3D digital data and of this atlas are: 1. The original digital datasets are freely rotatable in three dimensions, thus expected to be useful for any disciplines and anatomical interest, using any coordinate system, 2. Combined Nissl stained and MRI images are obtained from the same marmoset, to allow cross-modality matched references for multiple usages, 3. 86 Horizontal Series of Images with Neurosurgical Plane (based on the actual data), with more accuracy and resolution (Chapter 2) than the web-based digital images, 4. 32 Coronal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 3), 5. 10 Parasagittal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 4), 6. 3 Omnidirectionally Sliceable Planes (reproduced from the brain model) (Chapter 5), 7. In order to provide higher resolution structures to match systematic accuracy for supplementation of the digital data on the website, additional information are included. They are: 1) Nomenclature, 2) List of Brain Structures in Hierarchical Order, 3) Index of Abbreviations, together with 143 useful Bibliographic References list as of 2016, 8. Horsley-Clarke's stereotaxic coordinates were adopted in the present atlas.

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

For courses in Two-Semester A&P. Using Art Effectively with the Most Visual Approach to A&P Visual Anatomy & Physiology combines a one-of-a-kind visual approach with a modular organization that uniquely meets the needs of today's students—without sacrificing the comprehensive coverage of A&P topics required for careers in nursing and other allied health professions. The 3rd Edition presents key new features based on recent research about how information is used and digested. New modules in the first chapter emphasize how to use art effectively when studying; new Integrated Figure Questions increases the likelihood you will spend time viewing the art and prompts you to consider what you have just learned; and new SmartArt Videos, accessible via QR code in the book,help in navigating key, complex pieces of art on some of the toughest topics. New Interactive Physiology 2.0 tutorials, SmartArt Video Activities, and a mobile-friendly eText expand the options for students to use Mastering ™ A&P as an effective practice and learning tool. Also available with Mastering A&P Mastering™ A&P is an online homework, tutorial, and assessment program designed to engage students and improve results. Instructors ensure that students arrive ready to learn by assigning educationally effective content before class, and encourage critical thinking and retention with in-class resources such as Learning Catalytics™. Students can further master concepts after class through assignments that provide hints and answer-specific feedback. With a wide range of activities available, students can actively learn, understand, and retain even the most difficult concepts. Note: You are purchasing a standalone product; Mastering™ A&P does not come packaged with this content. Students, if interested in purchasing this title with Mastering A&P, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering A&P, search for: 0134396405 / 9780134396408 Visual Anatomy & Physiology Plus Mastering A&P with eText -- Access Card Package Package consists of: 0134394690 / 9780134394695 Visual Anatomy & Physiology 0134469550 / 9780134469553 Mastering A&P with Pearson eText -- ValuePack Access Card -- for Visual Anatomy & Physiology Mastering A&P should only be purchased when required by an instructor.

Learn about the human body from the inside out Some people think that knowing about what goes on inside the human body can sap life of its mystery—which is too bad for them. Anybody who's ever taken a peak under the hood knows that the human body, and all its various structures and functions, is a realm of awe-inspiring complexity and countless wonders. The dizzying dance of molecule, cell, tissue, organ, muscle, sinew, and bone that we call life can be a thing of breathtaking beauty and humbling perfection. Anatomy & Physiology For Dummies combines anatomical terminology and function so you'll learn not only names and terms but also gain an understanding of how the human body works. Whether you're a student, an aspiring medical, healthcare or fitness professional, or just someone who's curious about the human body and how it works, this book offers you a fun, easy way to get a handle on the basics of anatomy and physiology. Understand the meaning of terms in anatomy and physiology Get to know the body's anatomical structures—from head to toe Explore the body's systems and how they interact to keep us alive Gain insight into how the structures and systems function in sickness and health Written in plain English and packed with beautiful illustrations, Anatomy & Physiology For Dummies is your guide to a fantastic voyage of the human body.

A gleefully gruesome look at the actual science behind the most outlandish, cartoonish, and impossible deaths you can imagine What would happen if you took a swim outside a deep-sea submarine wearing only a swimsuit? How long could you last if you stood on the surface of the sun? How far could you actually get in digging a hole to China? Paul Doherty, senior staff scientist at San Francisco's famed Exploratorium Museum, and writer Cody Cassidy explore the real science behind these and other fantastical scenarios, offering insights into physics, astronomy, anatomy, and more along the way.Is slipping on a banana peel as hazardous to your health as the cartoons imply? Answer: Yes. Banana peels ooze a gel that turns out to be extremely slippery. Your foot and body weight provide the pressure. The gel provides the humor (and resulting head trauma). Can you die by shaking someone's hand? Answer: Yes. That's because, due to atomic repulsion, you've never actually touched another person's hand. If you could, the results would be as disastrous as a medium-sized hydrogen bomb. If you were Cookie Monster, just how many cookies could you actually eat in one sitting? Answer: Most stomachs can hold up to sixty cookies, or around four liters. If you eat or drink more than that, you're approaching the point at which the cookies would break through the lesser curvature of your stomach, and then you'd better call an ambulance to Sesame Street.

This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain.Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.

This textbook describes the biomechanics of bone, cartilage, tendons and ligaments. It is rigorous in its approach to the mechanical properties of the skeleton yet it does not neglect the biological properties of skeletal tissue or require mathematics beyond calculus. Time is taken to introduce basic mechanical and biological concepts, and the approaches used for some of the engineering analyses are purposefully limited. The book is an effective bridge between engineering, veterinary, biological and medical disciplines and will be welcomed by students and researchers in biomechanics, orthopedics, physical anthropology, zoology and veterinary science.This book also:Maximizes reader insights into the mechanical properties of bone, fatigue and fracture resistance of bone and mechanical adaptability of the skeletonIllustrates synovial joint mechanics and mechanical properties of ligaments and tendons in an easy-to-understand wayProvides exercises at the end of each chapter

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. - The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. - Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. - Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.

This volume offers a comprehensive history of the Mount Desert Island Biological Laboratory (MDIBL), one of the major marine laboratories in the United States and a leader in using marine organisms to study fundamental physiological concepts. Beginning with its founding as the Harpswell Laboratory of Tufts University in 1898, David H. Evans follows its evolution from a teaching facility to a research center for distinguished renal and epithelial physiologists. He also describes how it became the site of major advances in cytokinesis, regeneration, cardiac and vascular physiology, hepatic physiology, endocrinology and toxicology, as well as studies of the comparative physiology of marine organisms. Fundamental physiological concepts in the context of the discoveries made at the MDIBL are explained and the social and administrative history of this renowned facility is described.

An all-in-one guide to the human body!Anatomy 101 offers an exciting look into the inner workings of the human body. Too often, textbooks turn the fascinating systems, processes, and figures of anatomy into tedious discourse that even Leonardo Da Vinci would reject. This easy-to-read guide cuts out the boring details, and instead, provides you with a compelling lesson in anatomy. Covering every aspect of anatomical development and physiology, each chapter details the different parts of the human body, how systems are formed, and disorders that could disrupt bodily functions. You'll unravel the mysteries of anatomy with unique, accessible elements like:Detailed charts of each system in the bodyIllustrations of cross sectionsUnique profiles of the most influential figures in medical history From cell chemistry to the respiratory system, Anatomy 101 is packed with hundreds of entertaining facts that you can't get anywhere else!

Unsere Sinne - Sehen, Hören, Riechen, Schmecken und Tasten - bestimmen wesentlich unser Leben. Alles was wir wissen, wurde uns von unseren Sinnen vermittelt. Aber wie funktionieren unsere Sinne und wie kommt das Wissen über die Welt in unseren Kopf? Nach welchen Kriterien entscheidet unser Gehirn, was zu tun ist?In diesem Sachbuch wird allgemeinverständlich dargelegt, wie hoch entwickelt die Sinnesorgane bei Tieren und Menschen sind. Oft erreichen Sinnesleistungen die Grenze des physikalisch Möglichen. Das Buch erklärt, wie Sinnesreize erfasst werden, wie sie in die Sprache des Nervensystems übersetzt werden und wie unser Gehirn Sinnesinformation verarbeitet. Das Gehirn setzt dabei auf wohl bewährte Strategien, die ein Ziel verfolgen: die Überlebenschance des Organismus zu erhöhen. Deshalb wird in diesem Buch gezeigt, wie sehr die Sinnesleistungen durch die Evolution geformt und bestimmt wurden. Das Buch zeigt auch, dass viele Tiere ihre Umwelt vollkommen anders wahrnehmen als wir.

This new volume provides a concise overview of the most basic and exciting chapters of comparative medicine with regards to physiology and function in healthy individuals. The book includes core concepts in anatomy and physiology in human and animal models, which are key to understanding comparative medicine and to making contributions to research in this area. While writing this book, the authors were in constant interdisciplinary dialogue. They aim to contribute to improvements in quality of life for human and animal patients.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix'neuro'. Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a familiy of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as'reverse physiology'to uncover new peptides and orphan receptors.

In dieser interdisziplinären Arbeit auf dem Gebiet der Hirnforschung wird der Beziehung von EEG und Begabung bzw. Ausbildung im Bereich der Bildenden Kunst zum ersten Mal nachgegangen: Wie wird das Betrachten eines Bildes im Gehirn analysiert? Hängen Sehen und Verstehen zusammen? Wie kommt es zur Bildung einer inneren Gestalt in den entsprechenden Regionen des Gehirns? Die Untersuchungen der cerebralen Verarbeitung bei visuellen Vorgängen (Wahrnehmen, Vorstellen, Bild-Entwerfen) an insgesamt 38 Malerinnen und Nicht-Malerinnen stellen einen wesentlichen Beitrag zur Klärung der in der Literatur kontroversiell diskutierten Hemisphären-Spezialisierung dar. Während eine wesentliche Region für die Gestalt-Findung bei Nicht-Künstlerinnen linkshemisphärisch repräsentiert ist, ist ein Indikator der Begabung bei Malerinnen rechtshemisphärisch zu finden. Die Ergebnisse lassen darauf schließen, daß die Integration visueller Items Malerinnen wesentlich besser gelingt als Nicht-Malerinnen.

Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most widely studied disorder of the central nervous system. In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the vitally important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and also reviews microglial cell function and physiology. Cellular neurobiologists will find that this is a valuable guide to the importance and role of microglia in the CNS.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.