1. Extracellular Matrix and The Liver : Approach to Gene Therapy
- Author
-
Isao Okazaki, Yosifumi Ninomiya, Tanikawa Kyuichi, Scott I. Friedman, Isao Okazaki, Yosifumi Ninomiya, Tanikawa Kyuichi, and Scott I. Friedman
- Subjects
- Extracellular matrix, Liver--Cirrhosis--Gene therapy, Liver--Cirrhosis--Molecular aspects, Gene therapy
- Abstract
Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discussesnew strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapyapproaches. The chapters are divided into six sections as follows: - Basic Science of Extracellular Matrix - Cells Responsible for Extracellular Matrix Production - Activation Mechanism of Hepatic Cells and Signal Transduction - Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors - Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases - New Strategies for the treatment of Liver Cirrhosis - Discusses the possibility of gene therapy for liver cirrhosis - Includes information on new aspects of hepatic stellate cells - Written by top experts in basic science and clinical hepatology
- Published
- 2002