20 results
Search Results
2. Mathematical modeling of tumor-immune competitive system, considering the role of time delay.
- Author
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Khajanchi, Subhas and Nieto, Juan J.
- Subjects
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MATHEMATICAL models of the immune system , *TUMORS , *TIME delay systems , *COMPUTER simulation , *MATHEMATICAL models - Abstract
Highlights • A time delay model of the complex interaction between Tumor, CD8+T cells and T - helper cells. • The model undergoes Hopf bifurcation in which time delay plays an important role to destabilize the system. • Extensive numerical simulations are performed to validate our analytical findings. Abstract In this paper, we consider a three-dimensional nonlinear delay differential system (tumor cells, cytotoxic-T lymphocytes, T-helper cells) with single interaction delay. We perform linear stability of the equilibria and the existence of Hopf bifurcation in which the discrete time delay is used as a bifurcation parameter. We estimate the length of delay to preserve the stability of period-1 limit cycle. We also investigate the direction, period, and the stability of bifurcated periodic solutions by applying normal form method and center manifold theory. We observe that the discrete time delay plays an important role in stability switching. Numerical simulations are presented to illustrate the rich dynamical behavior of the model with different values for the time delay τ including the existence of periodic oscillations, which demonstrate the phenomena of long-term tumor relapse. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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3. Spatiotemporal dynamics and spatial pattern in a diffusive intraguild predation model with delay effect.
- Author
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Han, Renji and Dai, Binxiang
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SPATIOTEMPORAL processes , *ANALYTICAL mechanics , *MATHEMATICAL models , *THRESHOLD voltage , *COMPUTER simulation - Abstract
Based on biological meaning, a kind of diffusive intraguild predation (IGP: resource, IG prey and IG predator) model with delay effect is investigated in this paper. The model has Holling-Type I functional response between resource-IG prey and resource-IG predator; Holling-Type II functional response between IG prey and IG predator. We first give sufficient conditions on the stability of possible nonnegative constant steady-state solutions for the proposed model, which give us a complete picture of the global dynamics. Then we investigate Hopf bifurcation near the unique positive constant steady-state solution by taking delay as bifurcation parameter and derive the Hopf bifurcation threshold. It is shown that the delay can induce three types of bistability (node-node bistability, node-cycle bistability and cycle-cycle bistability), periodic oscillations and irregular oscillations triggering spatiotemporal chaos in the diffusive IGP model. Numerical simulations are performed to illustrate our theoretical results and suggest that delay can even trigger the emergence of self-organised spatiotemporal patterns, which evolve from spiral patterns to irregular spatial patterns via spatiotemporal Hopf bifurcation. In addition, the impact of diffusion on the model’s dynamics under certain time delay are also explored. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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4. A Michaelis–Menten type food chain model with strong Allee effect on the prey.
- Author
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Manna, Debasis, Maiti, Alakes, and Samanta, G.P.
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MICHAELIS-Menten mechanism , *FOOD chains , *ALLEE effect , *LAGRANGIAN points , *COMPUTER simulation - Abstract
Dynamical behaviours of a tritrophic food chain model with strong Allee effect in the prey are studied in this paper. Positivity and boundedness of the system are discussed. Some global results on extinction of the species are derived. Stability analysis of the equilibrium points is presented. The effect of discrete time-delay is studied, where the delay may be regarded as the gestation period of the superpredator. Numerical simulations are carried out to validate our analytical findings. Implications of our analytical and numerical findings are discussed critically. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
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5. Stability and bifurcation analysis of a stage structured predator prey model with time delay
- Author
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Kar, T.K. and Jana, Soovoojeet
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STABILITY theory , *PREDATION , *MATHEMATICAL models , *TIME delay systems , *HOPF bifurcations , *COMPUTER simulation - Abstract
Abstract: In this paper we proposed and analyzed a prey predator system with stage-structured for the predator population. A time delay is incorporated due to the gestation for the matured predator. All the possible non-negative equilibria are obtained and their local as well as global behavior are studied. Choosing delay as a bifurcation parameter, the existence of the Hopf bifurcation of the system has been investigated. Moreover, we use the normal form method and the center manifold theorem to examine the direction of the Hopf bifurcation and the nature of the bifurcating periodic solution. Some numerical simulations are given to support the analytical results. Some interesting conclusions are obtained from our analysis and it is given at the end of the paper. [Copyright &y& Elsevier]
- Published
- 2012
- Full Text
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6. Global stability and Hopf bifurcations of an SEIR epidemiological model with logistic growth and time delay.
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Xu, Rui, Wang, Zhili, and Zhang, Fengqin
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STABILITY theory , *HOPF bifurcations , *COMPUTER simulation , *EPIDEMIOLOGICAL models , *LOGISTICS , *TIME delay systems - Abstract
In this paper, an SEIR epidemiological model with saturation incidence and a time delay describing the latent period of the disease is investigated, where it is assumed that the susceptible population is subject to logistic growth in the absence of the disease. By analyzing the corresponding characteristic equations, the local stability of a disease-free equilibrium and an endemic equilibrium is discussed. The existence of Hopf bifurcations at the endemic equilibrium is established. By means of Lyapunov functionals and LaSalle’s invariance principle, it is proved that if the basic reproduction number is less than unity, the disease-free equilibrium is globally asymptotically stable and the disease dies out; if the basic reproduction number is greater than unity, sufficient conditions are obtained for the global stability of the endemic equilibrium. Numerical simulations are carried out to illustrate some theoretical results. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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7. Stability and Hopf bifurcation analysis of a ratio-dependent predator–prey model with two time delays and Holling type III functional response.
- Author
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Wang, Xuedi, Peng, Miao, and Liu, Xiuyu
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STABILITY theory , *HOPF bifurcations , *PREDATION , *INTERNATIONAL relations , *COMPUTER simulation - Abstract
In this paper, a delayed ratio-dependent predator–prey model with Holling type III functional response and stage structure for the predator is considered. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the system is addressed and the existence of Hopf bifurcations at the coexistence equilibrium is established. By utilizing normal form method and center manifold theorem, the explicit formulas which determine the direction of Hopf bifurcation and the stability of bifurcating period solutions are derived. Finally, numerical simulations supporting the theoretical analysis are given. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
8. Effects of additional food on an ecoepidemic model with time delay on infection.
- Author
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Sahoo, Banshidhar and Poria, Swarup
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EPIDEMIOLOGICAL models , *TIME delay systems , *HOPF bifurcations , *STABILITY theory , *COMPUTER simulation - Abstract
We propose a predator–prey ecoepidemic model with parasitic infection in the prey. We assume infection time delay as the time of transmission of disease from susceptible to infectious prey. We examine the effects of supplying additional food to predator in the proposed model. The essential theoretical properties of the model such as local and global stability and in addition bifurcation analysis is done. The parameter thresholds at which the system admits a Hopf bifurcation are investigated in presence of additional food with non-zero time lag. The conditions for permanence of the system are also determined in this paper. Theoretical analysis results are verified through numerical simulations. By supplying additional food we can control predator population in the model. Most important observation is that we can control parasitic infection of prey species by supplying additional food to predator. Eliminating the most infectious individuals from the prey population, predator quarantine the infected prey and prevent the spreading of disease. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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9. Stability and Hopf bifurcation in a model of gene expression with distributed time delays.
- Author
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Yongli Song, Yanyan Han, and Tonghua Zhang
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STABILITY theory , *HOPF bifurcations , *GENE expression , *TIME delay systems , *KERNEL (Mathematics) , *COMPUTER simulation , *MATHEMATICAL models - Abstract
In this paper, we consider the effect of distributed time delays on dynamics of a mathematical model of gene expression. Both the weak and strong delay kernels are discussed. Sufficient conditions for the local stability of the unique equilibrium are obtained. Taking the average delay as a bifurcation parameter, we investigate the direction of the Hopf bifurcations and the stability of the bifurcating periodic solutions by using the method of multiple time scales. Finally, numerical simulation is carried out to illustrate our theoretical results. It shows both subcritical and supercritical Hopf bifurcations can happen. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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10. Dynamical behavior of a food chain model with prey toxicity.
- Author
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Li, Ya and Xue, Yumei
- Subjects
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EFFECT of poisons on plants , *HERBIVORES , *PLANT species , *FOOD chains , *HOPF bifurcations , *PREDATION , *COMPUTER simulation , *MATHEMATICAL models - Abstract
This paper deals with a three-dimensional plant-herbivore-predator model that incorporates explicitly the plant toxicity in plant-herbivore interactions. The existence and stability conditions of all the feasible equilibria are established. Our results indicate that plant toxicity may play a key role in the dynamical behavior of the system. By adding another plant species with a different toxicity level to this system, we derive threshold conditions on the invasion of the second plant species. The analysis indicates that several parameters may be critical to determine successful invasion. Numerical simulations are also provided to reinforce the theoretical conclusions. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
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11. Hopf bifurcation analysis for a ratio-dependent predator–prey system with two delays and stage structure for the predator.
- Author
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Deng, Lianwang, Wang, Xuedi, and Peng, Miao
- Subjects
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HOPF bifurcations , *PREDATION , *COMPUTER simulation , *MATHEMATICAL analysis , *NUMERICAL solutions to differential equations - Abstract
Abstract: The ratio-dependent theory is favored by researchers since it is more suitable for describing the relationship between predator and its prey. In this paper, a ratio-dependent predator–prey system with Holling type II functional response, two time delays and stage structure for the predator is investigated. Firstly, by choosing the two time delays as the bifurcation parameter, the sufficient conditions for the local stability and the existence of Hopf bifurcation with respect to both delays are established. Furthermore, based on the normal form method and center manifold theorem, explicit formulas are derived to determine the direction of Hopf bifurcation and stability of the bifurcating periodic solution. Finally, numerical simulations are given to verify the theoretical analysis. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
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12. Hopf bifurcation of an epidemic model with a nonlinear birth in population and vertical transmission.
- Author
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Yinying, Zhang and Jianwen, Jia
- Subjects
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MATHEMATICAL models of Hopf bifurcations , *VERTICAL transmission (Communicable diseases) , *INFECTIOUS disease transmission , *NONLINEAR theories , *EPIDEMICS , *EXISTENCE theorems , *COMPUTER simulation - Abstract
Abstract: In this paper, an epidemic model involving a nonlinear birth in population and vertical transmission was studied. When , the disease-free equilibrium was stable, while if , the disease-free equilibrium was unstable. We researched the existence of Hopf bifurcation and obtained the stability and direction of the Hopf bifurcation by using the normal theory and the center manifold theorem. Numerical simulations were carried out to illustrate the main theoretical results and a brief discussion was given to conclude this work. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
- View/download PDF
13. Bifurcation analysis of the generalized stretch-twist-fold flow.
- Author
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Bao, Jianghong and Yang, Qigui
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COMPUTER simulation , *BIFURCATION theory , *SYSTEMS theory , *PARAMETER estimation , *ORBIT method , *STABILITY theory - Abstract
Abstract: Based on the stretch-twist-fold flow, a generalized stretch-twist-fold flow is introduced. By choosing an appropriate bifurcation parameter, Hopf bifurcations occur in this system when the bifurcation parameter exceeds a critical value. The formulae for determining the direction of the Hopf bifurcations and the stability of bifurcating periodic solutions are presented. In addition, the paper also investigates the bifurcations of the heteroclinic orbits for this system. The existence and its associated existing regions are given for two heteroclinic orbits, respectively. Finally, some numerical simulations for justifying the theoretical analysis are presented. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
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14. Hopf bifurcation analysis and amplitude control of the modified Lorenz system.
- Author
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Wang, Xuedi, Deng, Lianwang, and Zhang, Wenli
- Subjects
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HOPF bifurcations , *CONTROL theory (Engineering) , *LORENZ equations , *CENTER manifolds (Mathematics) , *MATHEMATICS theorems , *COMPUTER simulation , *FEEDBACK control systems - Abstract
Abstract: This paper is concerned with the Hopf bifurcation analysis and amplitude control of the modified Lorenz system. The Hopf bifurcation of system is investigated by utilizing the Hopf bifurcation theory and the center manifold theorem firstly. Then the direction and stability of limit cycle emerging from Hopf bifurcation are determined by the designed controller. Moreover, the amplitude of limit cycle emerging from Hopf bifurcation is controlled by a nonlinear feedback controller. Finally, numerical simulations are given to verify theoretical analysis. [Copyright &y& Elsevier]
- Published
- 2013
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15. Hopf bifurcation analysis of a system of coupled delayed-differential equations
- Author
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Çelik, C. and Merdan, H.
- Subjects
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HOPF bifurcations , *COUPLED mode theory (Wave-motion) , *NUMERICAL solutions to delay differential equations , *CENTER manifolds (Mathematics) , *COMPUTER simulation , *PERIODIC functions - Abstract
Abstract: In this paper, we have considered a system of delay differential equations. The system without delayed arises in the Lengyel–Epstein model. Its dynamics are studied in terms of local analysis and Hopf bifurcation analysis. Linear stability is investigated and existence of Hopf bifurcation is demonstrated via analyzing the associated characteristic equation. For the Hopf bifurcation analysis, the delay parameter is chosen as a bifurcation parameter. The stability of the bifurcating periodic solutions is determined by using the center manifold theorem and the normal form theory introduced by Hassard et al. (1981) [7]. Furthermore, the direction of the bifurcation, the stability and the period of periodic solutions are given. Finally, the theoretical results are supported by some numerical simulations. [Copyright &y& Elsevier]
- Published
- 2013
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16. Hopf bifurcation and stability for a neural network model with mixed delays
- Author
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Bi, Ping and Hu, Zhixing
- Subjects
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BIFURCATION theory , *STABILITY (Mechanics) , *ARTIFICIAL neural networks , *NETWORK time delays , *HOPF algebras , *ESTIMATION theory , *COMPUTER simulation - Abstract
Abstract: A generalized model of the two-neuron network with mixed delays is studied. The main purpose of this paper is to explore the linear stability of the trivial solution and Hopf bifurcation of a two-neuron network with continuous and discrete delays. The general formula of the direction, the estimation formula of period and stability of bifurcated periodic solutions are also studied. Finally, the numerical simulations are given to illustrate the theoretical analysis. [Copyright &y& Elsevier]
- Published
- 2012
- Full Text
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17. Dynamics of a competitive Lotka–Volterra system with three delays
- Author
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Liao, Maoxin, Tang, Xianhua, and Xu, Changjin
- Subjects
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BIFURCATION theory , *MANIFOLDS (Mathematics) , *COMPUTER simulation , *EQUILIBRIUM , *MATHEMATICAL formulas , *MATHEMATICAL analysis , *NUMERICAL analysis - Abstract
Abstract: In this paper, a competitive Lotka–Volterra system with three delays is investigated. By choosing the sum of three delays as a bifurcation parameter, we show that in the above system, Hopf bifurcation at the positive equilibrium can occur as crosses some critical values. And we obtain the formulae determining direction of Hopf bifurcation and stability of the bifurcating periodic solutions by using the normal form theory and center manifold theorem. Finally, numerical simulations supporting our theoretical results are also included. [Copyright &y& Elsevier]
- Published
- 2011
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18. Hopf bifurcation and stability for a differential-algebraic biological economic system
- Author
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Zhang, Guodong, Zhu, Lulu, and Chen, Boshan
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BIFURCATION theory , *H-spaces , *DIFFERENTIAL-algebraic equations , *PREDATION , *ECONOMIC impact , *COMPUTER simulation , *STABILITY (Mechanics) - Abstract
Abstract: In this paper, we analyze the stability and Hopf bifurcation of the biological economic system based on the new normal form and the Hopf bifurcation theorem. The basic model we consider is owed to a ratio-dependent predator–prey system with harvesting, compared with other researches on dynamics of predator–prey population, this system is described by differential-algebraic equations due to economic factor. Here μ as bifurcation parameter, it is found that periodic solutions arise from stable stationary states when the parameter μ increases close to a certain limit. Finally, numerical simulations illustrate the effectiveness of our results. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
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19. Dynamical behavior of a virus dynamics model with CTL immune response
- Author
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Zhou, Xueyong, Shi, Xiangyun, Zhang, Zhonghua, and Song, Xinyu
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BIOLOGICAL mathematical modeling , *VIRUSES , *BIFURCATION theory , *HOPF algebras , *IMMUNE response , *ASYMPTOTIC expansions , *COMPUTER simulation - Abstract
Abstract: In this paper, the dynamical behavior of a virus dynamics model with CTL immune response is studied. Sufficient conditions for the asymptotical stability of a disease-free equilibrium, an immune-free equilibrium and an endemic equilibrium are obtained. We prove that there exists a threshold value of the infection rate b beyond which the endemic equilibrium bifurcates from the immune-free one. Still for increasing b values, the endemic equilibrium bifurcates towards a periodic solution. We further analyze the orbital stability of the periodic orbits arising from bifurcation by applying Poore’s condition. Numerical simulation with some hypothetical sets of data has been done to support the analytical findings. [Copyright &y& Elsevier]
- Published
- 2009
- Full Text
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20. Memory-based movement with spatiotemporal distributed delays in diffusion and reaction.
- Author
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Song, Yongli, Wu, Shuhao, and Wang, Hao
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HOPF bifurcations , *SPATIAL memory , *ANIMAL mechanics , *ANIMAL species , *COMPUTER simulation , *DIFFUSION coefficients - Abstract
• Propose a general single species animal movement model with distributed delays in diffusion and reaction. • Investigate the impact of spatiotemporal delays on stability of memory-based model. • Obtain conditions for the occurrence of Hopf and steady state bifurcations. • Explore dynamics due to the interaction of Hopf and steady state bifurcations. In this paper, we investigate the spatiotemporal dynamics of a single-species model with spatiotemporal delays characterizing spatial memory and maturation. Through stability and bifurcation analysis, we find that the spatial memory-based diffusion coefficient, the spatiotemporal diffusive delay and spatiotemporal reaction delay have important effects on the dynamics of the model and their combined impact can cause the destabilization of the positive constant steady state and give rise to steady state and Hopf bifurcations. Taking the coefficient of spatial memory diffusion as the bifurcation parameter, the critical values of steady state and Hopf bifurcations are rigorously determined. Furthermore, we apply the theoretical results to a modified diffusive logistic model with predation and obtain spatially inhomogeneous steady states and spatially homogeneous and inhomogeneous periodic solutions via numerical simulations. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
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