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Hydroxyapatite (HAP) is the main inorganic component of human skeletal tissue such as bone, teeth et al. Because of its excellent biocompatibility, biodegradability and mechanical properties, it is widely applied in the field of medicine, particularly in bone repairing and drug release. However, it is difficult to prepare HAP particles with good dispersity in aqueous solution and high surface area. To solve the issue, porous CaCO 3 were taken as a template to prepare hydroxyapatite with good dispersity and high surface area assisted by a dipeptide hydrogel system. Experimental data show that the sequence of dipeptide has a great effect on the dispersity of hydroxyapatite particles, and the obtained hydroxyapatite has a same particle size with the template of CaCO 3 , and can be dispersed in an aqueous solution very well. Meanwhile porous hydroxyapatite particles have a large surface area benefiting the loading of model drugs, and illustrate enhanced cell internalization efficiency and low cytotoxicity, which can be used as a sustained-release drug carrier. [ABSTRACT FROM AUTHOR]

Flexible transient electronic devices have great potential applications in medical care and wearable device field. Herein, silk fibroin, a natural protein, was applied as biocompatible and biodegradable building blocks to construct transparent film with extraordinary mechanical property. During the preparation of film, conductive Ag nanowires have been introduced into the film through a patterned "casting" strategy, endowing the film with good conductivity. The silk fibroin film with patterned Ag nanowires is certified to be an effective and stable interdigital capacitive sensor in normal environment, but can dissolve immediately within water in one minute. The method proposed here is simple, facile and low cost, and will promote the development and application of transient electronics in security of information and wearable device fields. [ABSTRACT FROM AUTHOR]