1. Functional vision and cognition in infants with congenital disorders of the peripheral visual system.
- Author
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Dale, Naomi, Sakkalou, Elena, O'Reilly, Michelle, Springall, Clare, De Haan, Michelle, and Salt, Alison
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VISION , *COGNITION , *CONGENITAL disorders , *VISION disorders in children , *CHILD development , *COGNITION disorders , *LONGITUDINAL method , *PSYCHOLOGICAL tests , *RESEARCH funding , *VISION testing , *VISION disorders , *CROSS-sectional method , *SEVERITY of illness index , *DISEASE complications , *PSYCHOLOGY - Abstract
Aim: To investigate how vision relates to early development by studying vision and cognition in a national cohort of 1-year-old infants with congenital disorders of the peripheral visual system and visual impairment.Method: This was a cross-sectional observational investigation of a nationally recruited cohort of infants with 'simple' and 'complex' congenital disorders of the peripheral visual system. Entry age was 8 to 16 months. Vision level (Near Detection Scale) and non-verbal cognition (sensorimotor understanding, Reynell Zinkin Scales) were assessed. Parents completed demographic questionnaires.Results: Of 90 infants (49 males, 41 females; mean 13mo, standard deviation [SD] 2.5mo; range 7-17mo); 25 (28%) had profound visual impairment (light perception at best) and 65 (72%) had severe visual impairment (basic 'form' vision). The Near Detection Scale correlated significantly with sensorimotor understanding developmental quotients in the 'total', 'simple', and 'complex' groups (all p<0.001). Age and vision accounted for 48% of sensorimotor understanding variance. Infants with profound visual impairment, especially in the 'complex' group with congenital disorders of the peripheral visual system with known brain involvement, showed the greatest cognitive delay.Interpretation: Lack of vision is associated with delayed early-object manipulative abilities and concepts; 'form' vision appeared to support early developmental advance. This paper provides baseline characteristics for cross-sectional and longitudinal follow-up investigations in progress. A methodological strength of the study was the representativeness of the cohort according to national epidemiological and population census data. [ABSTRACT FROM AUTHOR]- Published
- 2017
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