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Froth Flotation is one of the fundamental processes used in iron ore attainment. It involves various physical–chemical reactions, and its multivariate control is not trivial. Traditionally, plant operators get quality measurements from laboratory analysis of sampled material, which can take hours to be published. In this paper, we present alternatives that eliminate both the necessity to periodically sample material as well as the delay associated with laboratory analysis: a predictive machine learning model working as a soft sensor. Two different classes of models were developed, exploring both deep and shallow approaches of machine learning, with a deep neural network architecture constructed for the particular task at hand. All models yielded accurate predictions, with results favoring the deep neural network when a larger volume of data is available. [ABSTRACT FROM AUTHOR]