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Repetitive high pulsed electric field (PEF) is an effective method to kill microorganisms and bacteria in water treatment applications. The PEF can be generated by applying high-power electromagnetic pulse across the sample to be treated. There are two main types of high-voltage pulse generators, namely, unipolar and bipolar. In this paper, a full-bridge submodule-based modular high-voltage pulse generator, having the ability to generate unipolar and bipolar high-voltage pulses with different shapes from a relatively low-voltage input dc supply, is proposed. In the proposed configuration, relatively low-voltage insulated gate bipolar transistors (IGBTs) are required to generate the high-voltage bipolar pulses. A thyristor rated at the level of the pulsed output voltage is required in the proposed configuration to bypass the load during the charging process of capacitors. In the proposed approach, a thyristor is used instead of the self-commutated high-voltage switch (e.g., series-connected IGBTs), as thyristors are available with high-voltage ratings and possess inherent reverse voltage blocking capability. A detailed illustration of the proposed configuration and its operational concept are introduced in this paper. Simulation and experimental results are presented to validate the proposed approach. [ABSTRACT FROM AUTHOR]