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Background. The deterministic fiber tracking method has the advantage of high computational efficiency and good repeatability, making it suitable for the noninvasive estimation of brain structural connectivity in clinical fields. To address the issue of the current classical deterministic method tending to deviate in the tracking direction in the region of crossing fiber region, in this paper, we propose an adaptive correction-based deterministic white matter fiber tracking method, named FTACTD. Methods. The proposed FTACTD method can accurately track white matter fibers by adaptively adjusting the deflection direction strategy based on the tensor matrix and the input fiber direction of adjacent voxels. The degree of correction direction changes adaptively according to the shape of the diffusion tensor, mimicking the actual tracking deflection angle and direction. Furthermore, both forward and reverse tracking techniques are employed to track the entire fiber. The effectiveness of the proposed method is validated and quantified using both simulated and real brain datasets. Various indicators such as invalid bundles (IB), valid bundles (VB), invalid connections (IC), no connections (NC), and valid connections (VC) are utilized to assess the performance of the proposed method on simulated data and real diffusion-weighted imaging (DWI) data. Results. The experimental results of the simulated data show that the FTACTD method tracks outperform existing methods, achieving the highest number of VB with a total of 13 bundles. Additionally, it identifies the least number of incorrect fiber bundles, with only 32 bundles identified as wrong. Compared to the FACT method, the FTACTD method reduces the number of NC by 36.38%. In terms of VC, the FTACTD method surpasses even the best performing SD_Stream method among deterministic methods by 1.64%. Extensive in vivo experiments demonstrate the superiority of the proposed method in terms of tracking more accurate and complete fiber paths, resulting in improved continuity. Conclusion. The FTACTD method proposed in this study indicates superior tracking results and provides a methodological basis for the investigating, diagnosis, and treatment of brain disorders associated with white matter fiber deficits and abnormalities. [ABSTRACT FROM AUTHOR]

This paper presents an automated and noninvasive technique to discriminate COVID-19 patients from pneumonia patients using chest X-ray images and artificial intelligence. The reverse transcription-polymerase chain reaction (RT-PCR) test is commonly administered to detect COVID-19. However, the RT-PCR test necessitates person-to-person contact to administer, requires variable time to produce results, and is expensive. Moreover, this test is still unreachable to the significant global population. The chest X-ray images can play an important role here as the X-ray machines are commonly available at any healthcare facility. However, the chest X-ray images of COVID-19 and viral pneumonia patients are very similar and often lead to misdiagnosis subjectively. This investigation has employed two algorithms to solve this problem objectively. One algorithm uses lower-dimension encoded features extracted from the X-ray images and applies them to the machine learning algorithms for final classification. The other algorithm relies on the inbuilt feature extractor network to extract features from the X-ray images and classifies them with a pretrained deep neural network VGG16. The simulation results show that the proposed two algorithms can extricate COVID-19 patients from pneumonia with the best accuracy of 100% and 98.1%, employing VGG16 and the machine learning algorithm, respectively. The performances of these two algorithms have also been collated with those of other existing state-of-the-art methods. [ABSTRACT FROM AUTHOR]

The novel coronavirus disease 2019 (COVID-19) is a contagious disease that has caused thousands of deaths and infected millions worldwide. Thus, various technologies that allow for the fast detection of COVID-19 infections with high accuracy can offer healthcare professionals much-needed help. This study is aimed at evaluating the effectiveness of the state-of-the-art pretrained Convolutional Neural Networks (CNNs) on the automatic diagnosis of COVID-19 from chest X-rays (CXRs). The dataset used in the experiments consists of 1200 CXR images from individuals with COVID-19, 1345 CXR images from individuals with viral pneumonia, and 1341 CXR images from healthy individuals. In this paper, the effectiveness of artificial intelligence (AI) in the rapid and precise identification of COVID-19 from CXR images has been explored based on different pretrained deep learning algorithms and fine-tuned to maximise detection accuracy to identify the best algorithms. The results showed that deep learning with X-ray imaging is useful in collecting critical biological markers associated with COVID-19 infections. VGG16 and MobileNet obtained the highest accuracy of 98.28%. However, VGG16 outperformed all other models in COVID-19 detection with an accuracy, F1 score, precision, specificity, and sensitivity of 98.72%, 97.59%, 96.43%, 98.70%, and 98.78%, respectively. The outstanding performance of these pretrained models can significantly improve the speed and accuracy of COVID-19 diagnosis. However, a larger dataset of COVID-19 X-ray images is required for a more accurate and reliable identification of COVID-19 infections when using deep transfer learning. This would be extremely beneficial in this pandemic when the disease burden and the need for preventive measures are in conflict with the currently available resources. [ABSTRACT FROM AUTHOR]

Automatic and accurate methods to estimate normalized regional brain volumes from MRI data are valuable tools which may help to obtain an objective diagnosis and followup of many neurological diseases. To estimate such regional brain volumes, the intracranial cavity volume (ICV) is often used for normalization. However, the high variability of brain shape and size due to normal intersubject variability, normal changes occurring over the lifespan, and abnormal changes due to disease makes the ICV estimation problem challenging. In this paper, we present a new approach to performICV extraction based on the use of a library of prelabeled brain images to capture the large variability of brain shapes. To this end, an improved nonlocal label fusion scheme based on BEaST technique is proposed to increase the accuracy of the ICV estimation. The proposed method is compared with recent state-of-the-art methods and the results demonstrate an improved performance both in terms of accuracy and reproducibility while maintaining a reduced computational burden. [ABSTRACT FROM AUTHOR]

Tongue image with coating is of important clinical diagnostic meaning, but traditional tongue image extraction method is not competent for extraction of tongue imagewith thick coating. In this paper, a novelmethod is suggested, which applies multi objective greedy rules and makes fusion of color and space information in order to extract tongue image accurately. A comparative study of several contemporary tongue image extraction methods is also made from the aspects of accuracy and efficiency. As the experimental results show, geodesic active contour is quite slow and not accurate, the other 3 methods achieve fairly good segmentation results except in the case of the tongue with thick coating, our method achieves ideal segmentation results whatever types of tongue images are, and efficiency of our method is acceptable for the application of quantitative check of tongue image. [ABSTRACT FROM AUTHOR]