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Start Over Author "Li, Liqiang" Journal journal of radioanalytical & nuclear chemistry Database Academic Search Index Publisher springer nature
1 results on '"Li, Liqiang"'

1. Production, quality control of next-generation PET radioisotope iodine-124 and its thyroid imaging.

Author

Wang, Feng, Liu, Teli, Li, Liqiang, Guo, Xiaoyi, Duan, Dongban, Liu, Zhibo, Zhu, Hua, and Yang, Zhi

Subjects
*QUALITY control, *POSITRON emission tomography, *THYROID gland radiography, *RADIOISOTOPES, *IODINE isotopes
Abstract

In this paper, 124Te(p,n)124I nuclear reaction was used for 124I production. The 124TeO2/Al2O3 target was irradiated by 12.5 MeV proton at 20 μA for 3-8 h in a medical cyclotron. After irradiation, 124I was purified by dry distillation and dissolved in 0.02 M NaOH, with radioactivity 370-1480 MBq. Micro-PET/CT imaging of 124I in healthy mice showed the thyroid and stomach accumulations and kidney metabolism, which may be useful for thyroid disease diagnosis. In summary, we have produced next-generation PET radioisotope 124I routinely in sufficient and high quality. [ABSTRACT FROM AUTHOR]

Published
2018
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