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The thin needle is viewed as a revolutionary object since it has a thinner thickness than a boundary layer. As a consequence, scientific and engineering applications for instance electrical equipment, hot wire anemometers and geothermal power generation are significantly impacted by the flow deformed by a thin moving needle. MHD Eyring–Powell fluid flow over a thin needle perceiving heat source, chemical reaction and nonlinear thermal radiation is the subject of the current investigation. In addition, the present study utilizes the Buongiorno model to examine the special effects of the fluid's Brownian and thermophoretic forces. The solution of the dimensionless form of ODEs is produced by applying exact renovations to the given problem, which is determined by the structure of PDEs. The bvp4c algorithm, based on the finite difference approach is utilized to numerically solve such modified ODEs. For validation, the results obtained indicate good agreement when compared to the literature. Finally, a detailed graphical analysis of key parameters is shown and explained while keeping in mind the physical significance of flow parameters. The results show that as magnetic and fluid parameter values improve, the velocity gradient falls. Increasing heat source and radiation parameters optimises heat transfer rate. The augmentation of the Lewis number and chemical reaction accelerates the rate of mass transfer on the surface. Brownian motion and thermophoresis provide enhanced thermal performance for the fluid temperature. Growing the thermophoresis parameter from 0.1 to 0.3 upsurges the Nusselt number by 5.47% and the Sherwood number by 12.26%. [ABSTRACT FROM AUTHOR]