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1. Regulating the diverse outcomes of interferon's interference.

Author

Marshall, Heather D. and Kaech, Susan M.

Subjects
*HEALTH outcome assessment, *INTERFERONS, *AUTOIMMUNE diseases, *T cells, *CELL culture, *EXPERIMENTAL medicine
Abstract

Regulatory T cells are crucial for preventing autoimmunity, but how their function is restrained to allow optimal effector T cells responses in appropriate contexts is unclear. In a recent paper in the Journal of Experimental Medicine, Campbell and colleagues demonstrate that virus-induced type I interferon acts directly on Treg cells to allow for functional antiviral T cell responses. [ABSTRACT FROM AUTHOR]

Published
2014
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