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Osteoporosis (OP) is a kind of bone disease related to aging. Its onset is obscure and development is gradual. Patients are without obvious clinical manifestations in the early stage. However, with the progress of the disease, bone loss and bone tissue microstructure destruction occur, and bone pain, spine deformation, and even osteoporotic fracture (OPF) and other serious complications may develop. Dual-energy X-ray absorption method is the current gold standard for clinical diagnosis of OP. Because its diagnostic accuracy is affected by the factors of body weight, lumbar degenerative changes, and aortic wall calcification, a false negative diagnosis is possible. In recent years, artificial intelligence (AI) has developed rapidly in the medical field. At present, AI has been widely used in the research of OP. Its research in the field of OP screening, diagnosis, and prediction has become a new hot spot. This paper expounds the application status and advantages of AI in OP diagnosis and treatment from four aspects, i.e., OP early screening, medical imaging performance, clinical diagnosis and treatment data, and OPF risk prediction, so as to provide a new direction for the accurate diagnosis and treatment of OP. [ABSTRACT FROM AUTHOR]