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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become pandemic, reaching almost one million death worldwide. At present standard treatment for coronavirus disease 2019 (COVID-19) is not well defined because the evidence, either from randomized or observational studies, with conflicting results, has led to rapid changes in treatment guidelines. Our aim was to narratively summarize the available literature on the management of COVID-19 in order to combine current evidence and interpretation of the data by experts who are treating patients in the frontline setting. The panel conducted a detailed review of the literature and eventual press releases from randomized clinical trials for each possible available treatment. Inductive PubMed search waws performed for publications relevant to the topic, including all clinical trials conducted. The result was a flowchart with treatment indications for patients with COVID-19. After 6 months of a pandemic situation and before a possible second coronavirus wave descends on Europe, it is important to evaluate which drugs proved to be effective while also considering that results from many randomized clinical trials are still awaited. Indeed, among treatments for COVID-19, only glucocorticoids have resulted in an association with a significant decrease in mortality in published randomized controlled trials. New therapeutic strategies are urgently needed. [ABSTRACT FROM AUTHOR]

Paper-based materials, due to their availability, environmental benefits and high thermal properties, have already been implemented in several building envelope designs. However, most of them either did not optimise the use of the material or did not provide sufficient thermal insulation for use in permanent buildings. The presented research analyses six original paper-based building envelope core proposals, suitable for use in permanent buildings in temperate climate of Europe, in terms of thermal and environmental efficiency. Proposals include cores with embedded paper tubes structural elements, timber-cardboard studs and sandwich designs. The heat transfer coefficient of the envelopes was obtained for repeatable modules via 2D computer simulations (ThermCAD software), and the environmental impact was assessed for a representative square metre of the envelope via LCA analysis, based in ecoinvent 3.8 database. All analysed designs showed high thermal insulation properties and met the requirements for U max = 0.20 W/m2K, did not cause the risk of surface condensation, nor have excessive thermal bridges. The analysed building envelope designs based on embedded frame wall structure showed environmental superiority over conventional envelopes (timber frame and SIP panels). The research may serve as a proof of concept, for using paper-based building envelopes in sustainable architecture. [ABSTRACT FROM AUTHOR]

The number of cancer patients in Europe is rising and significant advances in basic and applied cancer research are making the provision of optimal care more challenging. The concept of cancer as a systemic, highly heterogeneous and complex disease has increased the awareness that quality cancer care should be provided by a multidisciplinary team (MDT) of highly qualified healthcare professionals. Cancer patients also have the right to benefit from medical progress by receiving optimal treatment from adequately trained and highly skilled medical professionals. Built on the highest standards of professional training and continuing medical education, medical oncology is recognised as an independent medical specialty in many European countries. Medical oncology is a core member of the MDT and offers cancer patients a comprehensive and systemic approach to treatment and care, while ensuring evidence-based, safe and cost-effective use of cancer drugs and preserving the quality of life of cancer patients through the entire ‘cancer journey’. Medical oncologists are also engaged in clinical and translational research to promote innovation and new therapies and they contribute to cancer diagnosis, prevention and research, making a difference for patients in a dynamic, stimulating professional environment. Medical oncologists play an important role in shaping the future of healthcare through innovation and are also actively involved at the political level to ensure a maximum contribution of the profession to Society and to tackle future challenges. This position paper summarises the multifarious and vital contributions of medical oncology and medical oncologists to today's and tomorrow's professional cancer care. [ABSTRACT FROM AUTHOR]

The forest sector is vital in Europe, providing economic and social benefits to communities. However, this sector is also responsible for some environmental impacts, and it is crucial to ensure that these impacts do not outweigh the benefits described. For this reason, this paper proposes an environmental and economic assessment of three forest wood products – uncoated woodfree paper, natural cork stoppers, and particle boards. The life cycles of these products were modeled using foreground data and a life cycle assessment was conducted to determine the environmental impacts associated with these three life cycles. For the economic assessment, the net present value method was adopted. From the results, it is possible to conclude that the utilization of 1 ha of forest land for 100 years to plant Eucalyptus globulus used in the production of uncoated woodfree paper generates the least environmental impact per euro. A sensitivity analysis was conducted to determine the reliability of the results achieved given the uncertainty associated with the data used to model the three life cycles. The same critical impact categories and the same critical life cycle stage (raw materials' extraction) were identified for the three systems under study. Given these similarities, an effort must be made by the forest sector to reduce the impacts of these categories and this life cycle stage. To assist on this task, a set of generic and industry-specific recommendations is provided for companies operating in the forest sector. • An environmental and economic assessment of three forest wood products is performed. • The life cycle assessment methodology and the net present value method are used. • The production of uncoated woodfree paper generates the least environmental impact per euro of NPV. • Using sensitivity analysis, the results were found to be reliable. • Recommendations for different stakeholders in the forest sector are provided. [ABSTRACT FROM AUTHOR]

The paper by ESMO “The current and future role of the medical oncologist in the professional care for cancer patients: a position paper by the European Society for Medical Oncology (ESMO)” conveys some important key messages for the whole oncology community. A working group (WG) involving 21 oncology and related societies would like to comment on the ESMO position paper from a multidisciplinary perspective. The letter focuses on the concept of multidisciplinarity and how collaboration is the ideal situation for the best care of patients: the guidance to the patient must be given in accordance with agreements based on the outcome of discussions within the multidisciplinary team. The commentary therefore wants to highlight those statements that the working group shares and supports, identifying the common ground from where to start a constructive dialogue. [ABSTRACT FROM AUTHOR]

This paper discloses an innovative methodology for the generation and update of technology roadmaps to support strategic decisions for future hypersonic transportation systems, specifically targeting non-profit oriented R&D. The methodology is fully integrated into up-to-date conceptual design activity flows. It consists of five main steps that through mathematical and logical models moves from stakeholders' analysis up to planning definition and results evaluation. Complementary to the traditional experts-based methodologies, the rational process here presented allows for a well-structured logical definition of activities and/or missions required to enhance the readiness level of technologies, including a more accurate and reliable budget and time resources estimation to support the technology development plan. This methodology is exploited in the framework of the H2020 STRATOFLY Project to assess the potential of hypersonic civil vehicles to reach Technology Readiness Level 6 by 2035 with respect to key technological, societal and economical aspects. The paper discloses a unique assessment of the readiness level of the European air-breathing propulsive technologies. The final results confirm the crucial role of air-breathing propulsive technologies in the development of future hypersonic transportation system and highlight the urgent need to invest in in-flight demonstration missions with increasing functionalities, to target 2050 as entry in to service of the first Mach 8 civil transport. • Innovative Technology Roadmap Methodology for Hypersonic Transportation Systems. • Accurate time and budget resources estimation for each TRL transit. • Guidelines for the definition of activities, demonstrative missions or in-flight missions. • Technology Assessment of air-breathing propulsive technologies in Europe. • High-speed air-breathing technologies: TRL6 by 2035 and TRL9 by 2050 are confirmed. [ABSTRACT FROM AUTHOR]

• A novel approach for regional ionosphere grid model with high spatial-temporal resolution is suggested. • The results of the new model is analyzed at different disturb geomagnetic and solar conditions. • A comparative analysis between the results of new model, GIM, NeQuick and GPS-TEC is made. In this paper, a novel approach based on C1 finite element (FE) interpolation is used to construct a regional ionospheric grid model (RIGM) with high spatio-temporal resolution over Europe. The spatial resolution of the new model is 0.50 for a longitude and latitude and a temporal resolution is 15 min. Observations of 38 GPS stations at different days and seasons with different geomagnetic and solar activity conditions are used to evaluate the new method. All stations are used to discretize the whole domain of the problem into separate triangular patches using a Delaunay triangulation algorithm. In this case, GPS stations would be the vertices of the triangular patches. Also, the position of stations in sun-fixed coordinate system with coordinates of latitude and longitude are chosen in order to consider the temporal variations of vertical total electron content (VTEC). To model the behavior of VTEC in each triangular patch, a particular shape function is defined which is fitted to VTEC values at three vertices of each triangle while it satisfies C1 continuity of VTEC at the common edges of the adjacent triangles. The results of the new model are compared with the VTEC of GPS at 4 control stations as well as global ionosphere map (GIM) and NeQuick models. Statistical parameters, including correlation coefficient, root mean square error (RMSE), standard deviation and dVTEC = |VTEC GPS - VTEC model | have been used to evaluate the error of the models. In low geomagnetic activity (KP < 4), the average RMSE at 4 control stations for FE, GIM and NeQuick models are 0.89, 1.05 and 6.42 TECU, respectively, while in the high geomagnetic activity (KP > 4), they are 1.24, 1.68 and 7.62 TECU, respectively. For further analysis, the accuracy of three models in precise point positioning (PPP) has been also evaluated. In PPP method, there is an improvement of about 1–16 mm compared to GIM and NeQuick models at coordinate components of control stations in high geomagnetic activity. The results of the analysis performed in this paper show that the FE model has a very high capability and accuracy in regional VTEC modeling in high and low geomagnetic conditions. The regional accuracy of this model is higher than GIM and NeQuick models and therefore can be considered as a new model for the ionosphere. [ABSTRACT FROM AUTHOR]

The Baltic Dry Index (BDI) is an essential index to measure international dry bulk shipping freight, which can reflect global economic changes to a certain extent. Accurate forecasting of BDI supports shipping market participants in grasping risks and making scientific decisions. Based on the Prophet model, this paper considers the impact of multi-dimensional significant events related to the shipping industry and conducts BDI forecasting research. Firstly, we simulate the most momentous events in the world in recent years, namely the 2008 Global Financial Crisis and the 2019 New Crown Epidemic, and utilize the Prophet model to decompose the BDI sequence into three parts: trend, seasonality, and momentous event shocks. Secondly, we extensively collect other multi-dimensional significant event uncertainty indexes to establish a "significant event database". The Maximal Information Coefficient and Boruta methods were employed to extract the uncertainty index particularly correlated with BDI as an exogenous variable for forecasting. Then, we employ the K-Shape method to cluster exogenous variables and explore the combined sense of clustering. Finally, we utilize the Prophet model to forecast BDI in stages. It discusses the influence of exogenous variables and their cluster combinations on the forecasting effect individually and sequentially. Empirical results show that considering the two momentous events of the Financial Crisis and COVID-19 can remarkably improve the accuracy of BDI forecasting. In addition, the study of exogenous variable significance found that during the Financial Crisis, economic policy uncertainty in Europe and the Americas greatly impacted BDI forecasting. During COVID-19, global and developed economic policy uncertainty was noteworthy in the BDI forecasting. The comparative experimental results show the Prophet model has an exemplary forecasting result and strong robustness. It also performs excellently in model generalization and interpretability. This paper proposes a reliable and advanced algorithm for shipping freight rate index forecasting, which has noteworthy reference value for shipping market participants to make investment decisions and risk avoidance. [ABSTRACT FROM AUTHOR]

Over the past few years, energy communities initiatives have gained traction in Europe as a means to achieve energy transition goals, allowing citizen involvement in energy production, consumption, and distribution. Following the 2018 European directive RED II, these projects have rapidly increased across the continent, showcasing their potential for creating sustainable local energy systems. While studies highlight economic, environmental, and social benefits, barriers such as regulatory challenges, finance access, and low public awareness remain. This paper presents the results of a systematic literature review that explores the state-of-the-art of the academic research on energy communities. The study adopts a systematic approach to examine the body of literature on the topic to provide a comprehensive analysis of the phenomenon on the basis of rigorous and replicable research criteria. The reviewed material consists of 140 articles collected through the Scopus database, evaluated using specific structural dimensions to group the literature into analytical categories. The analysis of scientific papers published between 2018 and 2022 shows a growing attention towards Renewable Energy Communities, particularly those based on solar energy for electricity production, often combined with storage systems and heat pumps, whereas attention towards energy communities based on thermal energy production is still limited. Furthermore, most scholars focused on analysing specific territorial contexts; comparisons between different regions allows to highlight common features and elements characterizing each model. It emerged that the development of energy communities depends mainly on regulatory, financial, and managerial barriers that require an adequate institutional and legal framework capable of promoting their diffusion. Most studies address the topic from an economic perspective, often in association with incentivizing community models. However, a social perspective should be included by introducing the concept of energy sharing and methodologies for its distribution among all members of the community. The scientific community is called upon to continue investigating and supporting the development of community energy initiatives by providing evidence-based recommendations to policymakers, industry stakeholders, and local communities. This can help to overcome existing barriers and facilitate the diffusion of energy communities models, contributing to the achievement of sustainable and inclusive energy transition goals. • Systematic literature review exploring academic research on energy communities in Europe. • Structural dimensions and related analytical categories as framework to review 140 journal articles. • Most studies concern ECs based on renewable energy sources, with solar power being the predominant source. • Most employed technologies are related to the production of electricity from photovoltaic with batteries and heat pumps. • Most studied focus on Renewable Energy Community, while Citizens Energy Community are less considered in academic studies. [ABSTRACT FROM AUTHOR]

The ionospheric error affects the accuracy of the Global Navigation Satellite Systems observation and precise orbit determination. Usually, only the first order ionospheric error is considered, which can be eliminated by the ionospheric-free linear combination observation. But the remaining higher order ionospheric error will affect the accuracy of observations and their applications. In this paper, the influence of the higher order ionospheric error have been studied by using the International Geomagnetic Reference Field 13 and the Global Ionosphere Maps model produced by the Center for Orbit Determination in Europe. Focus on ionospheric error, the experiment of paper at doy 302 in 2019, which show that the second order ionospheric error impacting BeiDou Navigation Satellite System (BDS) B1I and B3I observation is 6.3569 mm and 11.8484 mm, respectively. Whereas, the third order ionospheric error impacting BDS B1I and B3I observation is 0.1734 mm and 0.3977 mm, respectively. Due to the current measurement accuracy of BDS carrier-phase observation can reach 2 mm, the influence of high order ionospheric error on observation should be considered. For BDS precise orbit determination, the orbit overlapping results are indicated that its orbit accuracy can be improved approximately 5 mm with the higher order ionospheric error correction, which is also in agreement with the results of Satellite Laser Ranging in this work. [ABSTRACT FROM AUTHOR]

• Investigation focuses on coupling link inspection, integral safety components to train screw coupling systems. • Plastic deformation increase, during operational use, did not affect yield stress or ultimate tensile strength. • Fractured links showed ductile fractures with distinctive surface structures. • 83 % of links, tested after 30 years in operation, exceeded the minimum breaking force. • Train brake analysis suggests a decrease in link failures due to other component issues. This paper presents an analysis of train screw coupling used mainly in Europe as mechanical connection of wagons in train. An analysis of train breaks apart incidents revealed that less than 30 % of the cases were caused by elements of the screw coupling, with coupling links accounting for only 5 % of the failures. Therefore, the investigation focused on testing the coupling links, which are safety elements of the screw coupling. The coupling links underwent various inspections, including visual inspection, dimensional control, non-destructive testing, examination of chemical composition, and mechanical tests. Dimensional control found longitudinal plastic deformations of the links. Chemical examination revealed that the links were made of different material than recommended, but their mechanical properties generally met the recommended values. However, variations were observed among different links, likely due to different rates of deformation during testing and operational conditions. Overall, the analysis and inspections provided insights into the condition and performance of coupling links in the screw coupling system, highlighting the importance of monitoring and maintaining these elements to ensure safe and efficient railway operations. [ABSTRACT FROM AUTHOR]

Policies aim to increase the penetration of renewable energy resources (RERs) to minimize the dependence on fossil fuels, have compelled different countries to devise their diverse blueprints by transforming smart grids infrastructure into futuristic grids or super smart grids (SSGs). Europe is taking the lead by developing SSGs by 2050, based on two exclusive alternatives, i.e., totally based on RERs and dispersed large decentralized networks. Critically assessing tensions in balancing load flow associated with RERs is a complicated task in SSGs. To solve this concern, the advanced probabilistic model is adopted in this research to observe the variations in demand and response profiles and mitigate it through transmission network planning using a super smart node transmission network topology (SSN). The proposed SSN transmission network topology outperforms the power synergy hub (PSHub) topology used in the existing literature through achieving an optimal load flow balancing in SSGs power infrastructure. This is also verified through simulation results, which provides an effective utilization of continuous spinning reserves (CSRs) and vehicle to grid (V2G) topologies integrated in an SSN transmission network topology for managing an optimized load flow balancing in SSGs. Additionally, this research work also provides a comprehensive overview of technical challenges in SSGs in terms of power flow control, their possible solutions, and future prospects. Finally, this paper concluded with the 2050 framework of futuristic SSGs, which provides a road map path for a sustainable and green energy environment for European infrastructure. [ABSTRACT FROM AUTHOR]

This paper delves into an econometric analysis to uncover the differences between Nordic European Countries - NEC (Norway, Denmark, Finland, Sweden) and South-East European Countries - SEEC (Greece, Bulgaria, Romania, Hungary). The focus is on exploring the interplay among electricity generation from Renewable Energy Sources (RES), CO 2 emissions, urban population and GDP per capita in these two European regions. The study employs cross-sectional dependence, first and second-generation panel unit root tests, Pedroni panel and Westerlund panel cointegration tests, ARDL, Dumitrescu-Hurlin causality test to establish the relation among variables. The findings reveal that in both regions, CO 2 emissions are significantly influenced by GDP per capita, urbanization and RES generation. Furthermore, urbanization plays an important role. When examining causality in SEEC, three bidirectional relationships are observed: urbanization and CO 2 , urbanization and GDP, urbanization and generation from RES, and two unidirectional causalities: CO 2 and GDP, generation from RES and CO 2. In contrast, for the NEC, there are two bidirectional causalities: urbanization and CO 2 , urbanization and generation from RES, and two unidirectional causalities: GDP and CO 2 , generation from RES and CO 2. These results highlight the nuanced and varied nature of environmental and economic dynamics across various European regions. • Relationship between CO 2 emissions, GDP per capita and electricity production from RES. • Investigating two groups of EU countries located in the North and SE Europe. • Estimations with Fully Modified and Dynamic Ordinary Least Squares. • Causality and cointegration between variables. [ABSTRACT FROM AUTHOR]

Shear reinforcement design has changed over time, along with the knowledge about the shear behaviour of reinforced concrete structures. Until the 1970s, the shear design in Europe was based on empirical limits for shear stress. The rules stipulated by the design standards often resulted in designs of concrete slabs with shear reinforcement consisting only of bent-up bars without any additional stirrups. Today, truss models are widely used to design shear reinforcement. However, in the structural assessment of bridges with bent-up bars, it is difficult to apply such models due to their specific detailing requirements. In order to evaluate the applicability of current design standards and to span the knowledge gap between the load-bearing behaviour of small-size specimens and actual structures, four shear tests on two full-scale replica bridge slabs containing bent-up bars are presented in this paper. The applied load configuration represents two-axle and four-wheel loads of the current load models for railway bridges stipulated by Eurocode 1–2 and train load model UIC 71. The load distribution due to a track superstructure consisting of a track, sleepers and ballast was investigated. A comparison of the obtained results with those of preliminary tests on narrow slab strips shows differences in the load-bearing behaviour of small-format laboratory tests. The results of the analysis of the bridge slabs according to various design standards show the potential of the newly developed potential shear crack model for the assessment of slab bridges with bent-up reinforcing bars. • Four shear tests on two full-scale replica bridge slabs containing bent-up bars. • Experimental investigation of the load distribution effect due to a complete track superstructure on the shear strength. • Comparison of the load-bearing behaviour of full-size slabs with small-format laboratory tests with a tenth of the width. • Analytical verification of the test results and discussion of shear models of various standards. [ABSTRACT FROM AUTHOR]

The capability to predict tritium retention and permeation by accurate and reliable tritium transport models for the breeding blanket design development is one of the most relevant objectives of the European Test Blanket Module (TBM) Programme. This also represents a key aspect for the development and licensing of next-future fusion systems and power plants, including the European DEMO. Tritium analyses can be performed using either system-level models to calculate global blanket and the related ancillary system performances or detailed 3D models for spatially limited areas and critical regions: the choice between these two modelling approaches depend on the objective of each analyse. When looking at the accuracy of tritium transport simulations, two main aspects have to be considered: the first one is the completeness of the description of the physical phenomena participating to the tritium transport dynamics; the second one is the reliability of the tritium transport material property values used in the simulation activities. In this context, this paper has the objective to carry out a critical analysis on the status of the integration of the most relevant multi-physics elements, providing recommendations on the approach to follow, with a particular focus on the system-level codes. Moreover, a set of data and correlations on tritium transport materials properties is proposed as a first step towards a material property database to be shared within the breeding blanket community. [ABSTRACT FROM AUTHOR]

The EU has committed to make Europe the first climate-neutral continent by 2050. Reaching this objective requires massive changes in the region. The biggest challenge is that the green transition happens without sacrificing economic progress and guaranteeing justice and inclusiveness. This pledge implies that every country be capable of addressing the trade-offs between targets while remaining committed towards the common decarbonisation goal. Our paper analyses the success with which countries are carrying out the energy transition. We propose an enhanced hyperbolic distance function and a stochastic frontier analysis approach to model the joint attainment of economic development, environmental sustainability, and energy equity. We apply our model to an unbalanced panel dataset of 29 European countries for the period 2005–2018. Our estimates show that the average performance of the economies has improved over time. The results also highlight the pivotal role of a sustainable economic development with clean energies for both slashing CO 2 emissions and fostering energy equity. Moreover, we find convergence in countries' performance, being this convergence slightly higher for the EU-15 countries compared to the rest. Finally, we show that a higher share of renewable energy sources helps countries that are lagging behind to reach their optimal performance level. [ABSTRACT FROM AUTHOR]

[Display omitted] Applications emitting radiofrequency electromagnetic fields (RF-EMF; 100 kHz to 300 GHz) are widely used for communication (e.g. mobile phones), in medicine (diathermy) and in industry (RF heaters). The objective is to systematically review the effects of longer-term or repeated local and whole human body radiofrequency electromagnetic field (RF-EMF) exposure on the occurrence of symptoms. Primary hypotheses were tinnitus, migraine and headaches in relation to RF-EMF exposure of the brain, sleep disturbances and composite symptom scores in relation to whole-body RF-EMF exposure. Eligibility criteria: We included case-control and prospective cohort studies in the general population or workers estimating local or whole-body RF-EMF exposure for at least one week. Information sources: We conducted a systematic literature search in various databases including Web of Science and Medline. Risk of bias: We used the Risk of Bias (RoB) tool developed by OHAT adapted to the topic of this review. Synthesis of results: We synthesized studies using random effects meta -analysis. Included studies: We included 13 papers from eight distinct cohort and one case-control studies with a total of 486,558 participants conducted exclusively in Europe. Tinnitus is addressed in three papers, migraine in one, headaches in six, sleep disturbances in five, and composite symptom scores in five papers. Only one study addressed occupational exposure. Synthesis of results: For all five priority hypotheses, available research suggests that RF-EMF exposure below guideline values does not cause symptoms, but the evidence is very uncertain. The very low certainty evidence is due the low number of studies, possible risk of bias in some studies, inconsistencies, indirectness, and imprecision. In terms of non-priority hypotheses numerous exposure-outcome combinations were addressed in the 13 eligible papers without indication for an association related to a specific symptom or exposure source. Limitations of evidence: This review topic includes various challenges related to confounding control and exposure assessment. Many of these aspects are inherently present and not easy to be solved in future research. Since near-field exposure from wireless communication devices is related to lifestyle, a particular challenge is to differentiate between potential biophysical effects and other potential effects from extensive use of wireless communication devices that may compete with healthy behaviour such as sleeping or physical activity. Future research needs novel and innovative methods to differentiate between these two hypothetical mechanisms. Interpretation: This is currently the best available evidence to underpin safety of RF-EMF. There is no indication that RF-EMF below guideline values causes symptoms. However, inherent limitations of the research results in substantial uncertainty. Funding: This review was partially funded by the WHO radioprotection programme. Registration: The protocol for this review has been registered in Prospero (reg no CRD42021239432) and published in Environment International (Röösli et al., 2021) [ABSTRACT FROM AUTHOR]

Inclusion of package leaflets in paper format is a legal requirement in European Union (EU), therefore the electronic package leaflet (ePL) is a relatively unknown phenomenon in medicinal products in Europe. Introduction of ePL only would be a more sustainable format of providing the product information than paper package leaflet. Furthermore, ePL would support health care professionals' comprehension of product use through electronic searchability and facilitate access to up-to-date product information in respective language used. It could also help us to tackle the availability issues and be a further step towards common packages. With this commentary, our aim is to review the ongoing ePL pilots in hospital settings in Europe and identify the benefits and challenges of ePL. Based on our review, there is a broad general support for the removal of paper package leaflets from hospital products. Packages without paper package leaflets are considered more sustainable due to savings in production and materials. Furthermore, ePL could be a facilitator for common packages in EU-countries with the benefit of reducing pharmaceutical waste and drug shortages. The most important benefit from both pharmaceutical industry and healthcare professionals' interest is that current and on-line updated product information is always electronically available, especially from drug safety perspective. [ABSTRACT FROM AUTHOR]

When we talk about Space, our interlocutors think about planets, stars, asteroids, astronauts and, sometimes satellites. But, only a small percentage is aware of what satellite technology can do and the relevance of satellite applications in our everyday life. From satellite communication, to navigation and to earth imagery, satellites data and technology are contributing in improving our daily life, or businesses or helping the management of our cities. Often, the end users come across an obstacle in communicating their needs to the service providers. On the other side, the service providers themselves are not fully aware how to communicate with the end-users. In some cases, this lack of communication makes difficult to meet the demand of space applications from the user side with the supply from the service providers. Eurisy, an association of space agencies established thirty years ago, works to put the end users at the core of the space value chain. In this last decades, Eurisy has been attentive and responsive to the changes of the space sector trying to picture how end users are becoming familiar with space technology. In particular, how the democratisation of space is turning space, especially satellite technology, into an enabler to guarantee the development of a sustainable living, accessible to everyone. Eurisy recently started a review of the case studies collected over the last ten years thanks to direct testimonials, event and conferences, publications and surveys. The user-centred approach adopted is innovative in the space sector and over the years proved to be effective in connecting users and service providers in different contexts. The paper aims at: 1- Identifying challenges and barriers that characterise the relations between service and/or information providers and end users. 2- Analysing the changes occurred in the relations between end users and service providers from 2007 to date in Europe. 3- Presenting the reasons that motivates the use of satellite data and technologies and which of these is the most used. 4- Presenting Eurisy's approach as an applicable model outside the European borders and the benefits deriving from connecting space and society. Furthermore, the paper will briefly present the ongoing activities as examples of the work put in place by the organisation and how the user-centred approach is applied. • The so-called democratisation of space has consequences on the downstream sector. • End users are mostly local and regional public authorities. • Central Europe seems to be the most fertile area where to find use cases. • The main technology adopted is Satellite Navigation. SatComs are not common. • Eurisy works putting the end-users central in the space value chain. [ABSTRACT FROM AUTHOR]

Bovine viral diarrhea virus (BVDV) is endemic in many parts of the world, and multiple countries have implemented surveillance activities for disease control or eradication. In such control programs, the disease-free status can be compromised by factors that pose risks for introduction or persistence of the virus. The aim of the present study was to gain a comprehensive overview of possible risk factors for BVDV infection in cattle herds in Europe and to assess their importance. Papers that considered risk factors for BVDV infection in cattle were identified through a systematic search. Further selection of papers eligible for quantitative analysis was performed using a predefined checklist, including (1) appropriate region (i.e., studies performed in Europe), (2) representativeness of the study population, (3) quality of statistical analysis, and (4) availability of sufficient quantitative data. In total, 18 observational studies were selected. Data were analyzed by a random-effects meta-analysis to obtain pooled estimates of the odds of BVDV infection. Meta-analyses were performed on 6 risk factors: herd type, herd size, participation in shows or markets, introduction of cattle, grazing, and contact with other cattle herds on pasture. Significant higher odds were found for dairy herds (odds ratio, OR = 1.63, 95% confidence interval, CI: 1.06–2.50) compared with beef herds, for larger herds (OR = 1.04 for every 10 extra animals in the herd, 95% CI: 1.02–1.06), for herds that participate in shows or markets (OR = 1.45, 95% CI: 1.10–1.91), for herds that introduced cattle into the herd (OR = 1.41, 95% CI: 1.18–1.69), and for herds that share pasture or have direct contact with cattle of other herds at pasture (OR = 1.32, 95% CI: 1.07–1.63). These pooled values must be interpreted with care, as there was a high level of heterogeneity between studies. However, they do give an indication of the importance of the most frequently studied risk factors and can therefore assist in the development, evaluation, and optimization of BVDV control programs. [ABSTRACT FROM AUTHOR]

As short-term variations existing in differential code bias of receivers (RDCB) will decrease the accuracies of extracting ionospheric observables by carrier-to-code leveling (CCL) method, a modified carrier-to code leveling (MCCL) method had been proposed to estimate RDCB offsets epoch by epoch in retrieval of ionospheric information. However, MCCL method is hampered by efficiency and precision at higher sampling intervals. To address RDCB offsets in higher sampling rate domain, a kernel model in the form of radial basis function (RBF) was chosen to model RDCB offsets produced by MCCL using lower sampling rate data in this paper. Owing to ill-posed problem induced by setting to many kernels, L1 norm regulation was employed to promote the sparsity of the problem and Fast iterative shrinkage thresholding algorithm (FISTA) was adopted to find the sparse solution. Data sets of 350 IGS stations evenly distributed in high-solar and low-solar activity years were chosen to illustrate the general existences of RDCB offsets and their dependence on solar activity. To validate the reliability and efficiency of the proposed method, two stations of them were selected out to construct the spares kernel model. As shown in experimental results, kernel model is of good performance in training data with over 90% sparsity rate and all standard deviations of the errors between original and fitting data are around 0.4 ns. It is a striking finding in terms of efficiency that the proposed method and CCL are much more efficient than MCCL in extracting ionospheric observables by means of fixed equipment. For further validations, generalized triangular series function (GTSF) was constructed using ionospheric observables derived from precise point positioning (PPP), CCL, MCCL and the proposed method. With Center for Orbit Determination in Europe (CODE) Global Ionospheric Map (GIM) regarded as reference, compared with VTEC estimates derived from CCL, those derived from MCCL and the proposed method have improved accuracies ranging from 10% to 20%. Overall, these results indicate that the proposed method has a promising application in retrieval of ionospheric observables in terms of accuracy and efficiency. [ABSTRACT FROM AUTHOR]

Frescoes were developed as religious paintings in medieval Europe before the rise of oil paintings. When coloring with natural pigments on a slaked lime plaster, calcium carbonate gradually forms a coating on the pigments at the surface of the plaster over a period of decades to a hundred years. Many frescoes have been maintained for hundreds of years and have become part of historic heritage. However, the making of frescoes is rarely selected as a general art painting method because it takes a lot of time for complete carbonation to occur. This study demonstrated that a geomimetic ceramic hardening technique using calcium hydroxide and calcium carbonate, followed by subsequent acceleration of carbonation at the surface of the calcium hydroxide with supercritical carbon dioxide, could assist in forming frescoes in a short time. The immobilization of the pigment used on the base calcium hydroxide body was evaluated by a scratch test with emery paper, and pigment color differences were measured by a colorimeter. Furthermore, the micromorphology of the resultant frescoes fabricated by the geomimetic technique in a short time was investigated to evaluate the progress of carbonation. As a result, frescoes could be fabricated in a short time by combining a geomimetic technique and carbonation with supercritical carbon dioxide using a novel pigment that is a mixture of pigment and calcium hydroxide. The pigment in the final sample was completely fixed to the base calcium hydroxide body, and the pigment color was brighter than the original pigment color due to the densification of calcium carbonate after supercritical carbon dioxide treatment. [ABSTRACT FROM AUTHOR]

Recent technological developments make perovskite solar cells (PSCs) particularly suitable for building integrated photovoltaic (BIPV) applications on vertical building envelopes, but the relatively short lifespan of PSCs requires frequent replacement, thereby generating substantial waste. Careful consideration of circularity credentials of this novel technology is therefore essential prior to the extensive implementation of vertical PSCs in building envelopes. This paper provides a circular economy approach for the implementation of PSCs in vertical envelopes and assesses its economic feasibility by life cycle cost analysis in Europe. The process of recycling PSC is developed. The economic performance of PSC envelopes is provided and compared to that of the conventional rigid BIPV system. Uncertainty analysis and sensitivity analysis of economic indicators are then performed to identify the influential parameters. The findings indicate that the PSC envelope has a significant potential for circular BIPV components and that PSCs applied on vertical envelope are economically viable. • LCCA of vertical PSC envelopes with recycling strategy is analyzed in Europe. • Recycling strategy of PSC is explored before diffusion to overcome PSC's short lifespan. • PSC price is the most influential factor for the deviation of LCOE. • PSC envelope has potential to achieve profitability in most regions of Europe. [ABSTRACT FROM AUTHOR]

Of the 4.4 million people diagnosed with cancer in Europe each year, around 36 % are of working age. Return-to-work rates vary across Europe. Work is important for the individual, as well as for society, and this review aims to provide an overview of the predictors for the return to work (RTW) process in European cancer survivors of working age. A systematic literature search was conducted. The present review included quantitative and qualitative study designs published since 2013. In total, the review included 85 papers examining cancer survivors with various cancer diagnoses in 18 European countries. Identified predictive factors for RTW related to the social system, treatment, disease, health behavior, the individuals' psychosocial, work, and sociodemographic situations. There is a need for a standardized definition and operationalization of RTW. Providers can use these results to identify survivors at risk and support cancer survivors in their RTW process. [Display omitted] • Cancer survivors' RTW is associated with various predictors. • The predictors vary over time and differ between cancer entities and countries. • Predictors can be used to identify survivors at risk and to extent support programs. [ABSTRACT FROM AUTHOR]

This paper proposes a set of digitalisation indicators focused on measuring the different digital capabilities and infrastructure of electricity distribution systems, as opposed to previous indicators which have mainly focused on performance and quality of service aspects. The indicators are classified according to the pillars of digitalisation: sensor and actuator, connectivity, data processing, and digital culture. They are use-case-agnostic and do not require a huge amount of information. In addition to this, three possible new applications of these indicators for distribution system operators and regulatory authorities are identified and discussed. The extensive use of these indicators in Europe could allow the development of fruitful collaborations between distribution system operators, allow the identification of cause–effect relations between grid performance and digital infrastructure, and improve the replicability of innovative smart grid solutions. However, this will only be possible if regulators promote the adoption of the proposed indicators and the dissemination of their results. • Smart grid indicators are required by European Directive 2019/944. • Indicators on sensors/actuators, connectivity, data processing, and digital culture. • Indicators to provide an overview of the distribution grid. • Indicators to study relation between performance and digital infrastructure. • Indicators to generate information for the replicability of solutions. [ABSTRACT FROM AUTHOR]

Fusion for Energy (F4E), the European Domestic Agency for ITER, is responsible for the procurement of the divertor inner vertical target (IVT) and the cassette body (CB). Both IVT and CB have been supported by extensive Research and Development (R&D) work programmes, implemented over more than 15 years in Europe, to validate design, develop various fabrication technologies, assess thermo-mechanical and thermohydraulics performances and RH installation and maintainability. This paper presents the work performed and the technical challenges associated to the fabrication of the CB prototypes, the results of the prototype qualification as well as the lessons learned. [ABSTRACT FROM AUTHOR]

• Primary care plays a major role in the diagnosis of cancer and care of patients • Primary and community care are often not well integrated into cancer care • There are many opportunities for extending care at the primary level • Healthcare systems must consider new roles for primary and community professionals ECCO Essential Requirements for Quality Cancer Care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to cancer patients. They are written by European experts representing all disciplines involved in cancer care. This paper concerns the integration of primary care into care for all cancers in Europe. Primary care integration: • Primary care professionals play major roles in the diagnosis of cancer and care of cancer patients • There are many opportunities for extending care at the primary level to cope with the increasing cancer burden and its nature as a chronic disease, but there are also significant barriers to progress towards high-quality patient-centred care • To meet European aspirations for comprehensive cancer control, healthcare organisations must consider the requirements in this paper to include primary and community care in patient-centred pathways from diagnosis to treatment and survivorship. [ABSTRACT FROM AUTHOR]

• Spatial and temporal variability of Es layer top frequency was analyzed. • Statistic Es layer top frequency at different seasons and phase of solar activity was performed. • The maps of the distribution of Es layer top frequency were produced. • The "cloud" model of Es layer was implemented in NIM-RT propagation model for ionogram simulations. This paper describes a study of the daily and yearly variability of one of the main characteristics of sporadic E layers (Es), the critical frequency (foEs). Our analysis is based on ionograms recorded by GIRO network ionosondes. The study estimates the spatial and temporal variability of the Es layer parameters and generates their statistics at different seasons and phases of the solar cycle. In turn, the statistics of the Es layer parameters can provide an assessment of the capability of the HF propagation forecasting. Further, maps of the distribution of Es layer critical frequency are produced. This paper implements the "cloud" model of Es layer in HF propagation model (Northern Ionosphere Model & Ray Tracing, NIM-RT) that can accurately reproduce many features observed in experimental measurements. Within this framework, a number of vertical sounding ionograms with the presence of Es layer are simulated based on the NIM-RT software. [ABSTRACT FROM AUTHOR]

The objective of this paper is to examine and provide a holistic assessment of the "Space and Security" Policy in Europe, taking into consideration the European and national Space Strategies, Programmes and Governance. The importance of security in European Union (EU) activities is increasing after a decade of unprecedented crises and challenges of multidimensional nature. Space, as an enabling tool in support of multiple policy areas, can contribute to national and supranational security objectives. Space can contribute to and ultimately reinforce the European integration process. The first part of this paper focuses on the description of the security aspects of the space activities in Europe. The analysis includes the two main extents of space security – security from space and security in space. The second part focuses on the security aspects of the European Union (EU), European Space Agency (ESA) and National Space strategies, policies and programmes. The importance of coordination and cooperation between the stakeholders is emphasised. The final part considers how the European "Space and Security" strategies and policies contribute to European Space Integration. • Overview of Space and Security in Europe. • Understanding of the Space Strategies, Programmes and Governance of ESA, EU and selected Member States. • Identification of security dimension of space activities from a space policy perspective. • Analysis of Space and Security Policy in the Frame of European Space Integration. [ABSTRACT FROM AUTHOR]

Reduced water availability poses risks for many economic activities. This paper studies how water risks affect hydroelectricity generation in Europe and the US and whether these risks are priced in by financial markets. To this end, we build a novel dataset for the period 2015–2022, which combines plant-specific hydroelectricity generation with geo-specific water physical risks and equity returns. We find that water risks, measured using model-based aggregate water risk metrics as well as precipitation anomalies, are significantly associated with reduced electricity generation, although the effect disap- pears after two months. We then link the power plants in our sample to the equity returns of their owners to investigate whether financial markets adequately price water risks. Using a portfolio sorts approach, we find weak evidence of a negative risk pre- mium. Given the real negative effect of water risks on generation, we conclude that the lack of a positive risk premium amounts to mispricing of water risks by financial markets. [Display omitted] • Hydroelectricity is key for the energy transition but faces challenges from fluctuations in water availability. • Higher water risk is associated with a 9% reduction in hydroelectricity generation in the driest year of our sample, 2022. • The occurrence of a precipitation anomaly leads to an 18% drop in hydroelectricity generation. • Despite the real negative effect of water risks, these risks are not priced in by financial markets. • The mispricing of water risks by financial markets calls for closer scrutiny by financial supervisors. [ABSTRACT FROM AUTHOR]

Hydrogen is among the energy carriers, which are most often considered for bringing about a sustainable energy system. Yet, so far, hydrogen has not delivered as an energy carrier. The core objective of this paper is to provide a comprehensive analysis of the state-of-the-art and the future prospects of green hydrogen in the European energy system from economic, energetic and CO 2 emissions point-of-view. The analysis shows that there are some increasing opportunities for hydrogen use in industry and in the transport sector, when electrification is not possible or is too expensive, as well as a storage in the European electricity system. However, a hydrogen-based energy system will remain a vision at least over the next decades. The major reason for this is the unfavorable economics mostly due to high investment costs in the whole supply chain. In addition, the overall efficiencies in the hydrogen chains are moderate in general. The full environmental benignity of hydrogen as an energy carrier is only provided when renewable energy sources are used for hydrogen production. However, in Europe, the potentials for green hydrogen are very limited due to the insufficient expansion of renewable electricity generation. For this reason, many European countries are considering options for green hydrogen import. The future of hydrogen is highly dependent on the supporting policy framework. To reduce the risk in the investment in hydrogen infrastructure, as well as to justify the promotion of green hydrogen, it is very important that Europe works out a very clear and realistic long-term implementation strategy. • Hydrogen might have potential in the European energy system, yet a hydrogen-based energy system stays visionary. • Green hydrogen from renewable electricity via electrolyzers is key for environmental benefits and decarbonization. • Hydrogen should be prioritized for uses where electrification is not feasible. [ABSTRACT FROM AUTHOR]

While concentrations of most air pollutants have been decreasing in Europe over the last 20 years, O 3 is showing variable trends, with increasing average and decreasing peak concentrations. The complexity of O 3 chemistry adds to the difficulty of understanding both the trends observed and how concentrations can be mitigated. This paper tries to answer the following questions: which emission sectors should be targeted and what levels of reduction could be achieved? To address these reflections, an Atlas of O 3 chemical regimes has been constructed. For this Atlas, 22 European cities were selected and the surrogate model Air Control Toolbox (ACT) was used to evaluate the simulated changes in several ozone metrics as a result of reductions in road transport and industrial emissions. O 3 chemical regimes have been classified and put in perspective with meteorological and emission data at each city location and around. The O 3 sensitivity to road transport and industrial emissions differ from one city to another, but also for the same city when considering different ozone metrics and seasons (e.g., annual means versus SOMO35 or summer peaks). Counterproductive impacts yielding O 3 increase when emissions are reduced are mainly encountered in regions or periods where O 3 concentration are relatively low. In terms of meteorological factors, O 3 chemical regimes are mostly impacted by the amount of solar radiation received but wind speed also has a considerable impact. Most cases show a higher sensitivity to emission reductions from road transport or equal sensitivity to emission reductions from road transport and industry. Very few cases are more sensitive to emissions from the industrial sector. However, the response of annual or seasonal average O 3 metrics to industrial and road transport emissions can be considered relatively low with a maximum reduction of 33% for a 100% reduction of both industrial and road transport emissions. This is because anthropogenic emission can only mitigate ozone above a substantial natural tropospheric background. It is precisely this incremental anthropogenic ozone, which should be targeted by efficient policies as we also demonstrate that none of the cities studied would exceed the European target value with a 100% reduction in emissions. • An atlas of ozone chemical regimes has been constructed for 22 European cities. • O 3 sensitivity to road transport and industrial emissions differ when considering different ozone metrics and different periods of the year. • Counterproductive effects of precursors emission reductions on ozone are a concern where and when ozone concentrations are low. • On the contrary, significant reductions of precursor emissions are found to reduce the number of exceedances of the EU target limit value. • In most cities, mitigation of road transport yields larger benefit to ozone air pollution than mitigation of the industrial sector. [ABSTRACT FROM AUTHOR]

• Investigation of GHG pollutants persistence in Europe and major economic areas. • Mean reversion properties and the integration factor is examined for CO2, CH4, and NO2 (2000-2021) • Empirical evidence of mean reversion in CO2 emissions across all countries. • CH4 and NO2 show reduced persistence and not all countries exhibit mean reversion properties. • These empirical findings highlight policy progress, but underscore the need for further efforts. This paper investigates the persistence of GHG in Europe, evaluating the effectiveness of government policies, including the Kyoto Protocol and the EU Council commitment. Mean reversion properties, and the structure of the integration factor were examined to determine the degree of persistence across markets and assess policy effectiveness. The analysis focuses on CO 2 , CH 4 , and NO 2 pollutants, with monthly data starting in January 2000 and ending in December 2021 from major European countries, and the US, Japan, Brazil, China, and India for comparison purposes. Empirical results show clear evidence of mean reversion in CO 2 emissions observed across all countries, indicating certain degrees of stabilization. Similar patterns are seen for CH 4 , and NO 2 , observing reduced persistence of these pollutants; however not all countries exhibit mean reversion properties. Thus, these findings highlight policy progress in stabilizing GHG emissions, particularly for CO 2 , but underscore the need for further efforts to achieve a substantial emissions reduction. [ABSTRACT FROM AUTHOR]

Due to the immense pressure of environmental pollution, economic growth and energy usage, green growth is recognized as the fundamental development strategy in Europe. This paper assesses environmental efficiency (ENE) of 54 industries from 28 European countries across the three sectors of an economy over the 2000–2014 period using a non-radial directional distance function (DDF). The aim of this study is to shed light and provide a deeper understanding of the different levels of technological heterogeneity that exist among industries by incorporating the metafrontier approach under distinct sector and country-specific production frontiers. The results reveal that industries present higher levels of environmental efficiency within their sectors while manufacturing industries achieve the lowest progress in environmental efficiency. Thus, it is critical to introduce and implement sector-oriented policies rather than common guidelines for all European countries. [ABSTRACT FROM AUTHOR]

• Paper describes a methodology that was successfully applied for the development of a temporary road traffic steel barrier in compliance with T1/W1 level according to EN 1317; • A simplified theoretical analysis of 178 barrier, laboratory test of three types of barrier connectors (for two types of barrier), explicit FEM modeling of four chosen barrier, and a full-scale crash test for final barrier are presented; • The stiffness of barrier connector was established based by laboratory barrier test (the FEM model was validated based on laboratory tests); • The chosen final barrier alternative passed the crash test for T1/W1 (TB21) containment level, performed by certified laboratory [35] , which proves that the presented procedure could be used successfully for traffic barrier development. Over a million people die in road crashes and tens of millions result injured or disabled each year, globally. Hence, there is a constant concern for improving the safety of the roads to protect road users, and those at the most risk, the road workers. Construction, maintenance, and utility work are constantly needed to ensure safety and functionality of roads and highways. Temporary road traffic barriers are used to separate passing traffic from the workspace and protect the workspace from an errant vehicle intrusion. Steel barriers are light, and their major advantage is rapid installation. These barriers are not anchored to the ground, and their behavior relies on the base-pavement friction, mass inertia, and stiffness of the system. The paper describes a methodology that was successfully applied for the development of a temporary road traffic steel barrier in compliance with the European specification EN 1317. The study included a simplified theoretical analysis of 178 barriers, static laboratory tests of three types of barrier connectors, development of explicit finite element models (EFEMs) of four selected barrier designs, and a full-scale crash test of the final barrier design. It is shown that static laboratory tests of complex connector systems can help to improve the design process and reduce the cost. The analysis and use of EFEMs was enough so that just a single full-scale crash test was sufficient for certification of the barrier design for use in Europe. The final barrier is compliant with the EN 1317–2 requirements for T1/W1 (TB21) containment level, which was confirmed by a full-scale crash test. [ABSTRACT FROM AUTHOR]

The importance of defining and establishing professional standards for Clinical Microbiology (CM) in Europe has long been highlighted, starting with the development of a European curriculum. The first European Curriculum in Medical Microbiology (MM) was adopted by the European Union of Medical Specialists (UEMS) council in 2017. This paper assesses how training programmes in CM in Europe align with the European curriculum, just under 5 years after its introduction, and reviews what methods of assessment are in use to assess the CM trainees' progress during training programmes. Using an internet-based platform, a questionnaire was circulated to the full, associate and observer members of the UEMS MM section. Information collected related to the structure, content and delivery of CM training in the participating countries, as well as methods of assessment used to evaluate training progress. Twenty-one countries responded, from a total of 30 countries invited to participate. All had a structured CM training programme, with a curriculum, dedicated trainers and a record of training activities. Fifteen countries require trainees to pass an exit examination, and over 60% of countries participate in continuous workplace-based assessment. Of the participating countries, 57% meet the European Training Requirements recommendation that duration of specialist training is 60 months. Regarding core competencies, all trainees gain experience in laboratory skills and infection prevention and control, but the emphasis on clinical management and antimicrobial stewardship is more varied across countries. The UEMS MM curriculum has been largely adopted by 21 countries within less than 5 years of ratification, which speaks optimistically to a future of standardized quality training across Europe. The introduction of a pilot European Examination in Clinical Microbiology in 2021 is the start of a pan-European assessment of the success of the implementation of this curriculum and the first step in quality assurance for CM training in Europe. [ABSTRACT FROM AUTHOR]

Abstract The increasing global demand for food and the environmental effects of reactive nitrogen losses in the food production chain, increase the need for efficient use of nitrogen (N). Of N harvested in agricultural plant products, 80% is used to feed livestock. Because the largest atmospheric loss of reactive nitrogen from livestock production systems is ammonia (NH 3), the focus of this paper is on N lost as NH 3 during the production of animal protein. The focus of this paper is to understand the key factors explaining differences in Nitrogen Use Efficiency (NUE) of animal production among various European countries. Therefore we developed a conceptual framework to describe the NUE defined as the amount of animal-protein N per N in feed and NH 3 N losses in the production of milk, beef, pork, chicken meat and eggs in The Netherlands, Switzerland, United Kingdom, Germany, Austria and Denmark. The framework describes how manure management and animal-related parameters (feed, metabolism) relate to NH 3 emissions and NUE. The results showed that the animal product with the lowest NUE had the largest NH 3 emissions and vice versa, which agrees with the reciprocal relationship between NUE and NH 3 within the conceptual framework. Across animal products for the countries considered, about 20% of the N in feed is lost as NH 3. The significant smallest proportion (12%) of NH 3 N per unit of N feed is from chicken production. The proportions for other products are 17%, 19%, 20% and 22% for milk, pork, eggs and beef respectively. These differences were not significantly different due to the differences among countries. For all countries, NUE was lowest for beef and highest for chicken. The production of 1 kg N in beef required about 5 kg N in feed, of which 1 kg N was lost as NH 3 N. For the production of 1 kg N in chicken meat, 2 kg N in feed was required and 0.2 kg was lost as NH 3. The production of 1 kg N in milk required 4 kg N in feed with 0.6 kg NH 3 N loss, the same as pork and eggs, but those needed 3 and 3.5 kg N in feed per kg N in product respectively. Except for beef, the differences among these European countries were mainly caused by differences in manure management practices and their emission factors, rather than by animal-related factors including feed and digestibility influencing the excreted amount of ammoniacal N (TAN). For beef, both aspects caused important differences. Based on the results, we encourage the expression of N losses as per N in feed or per N in product, in addition to per animal place, when comparing production efficiency and NUE. We consider that disaggregating emission factors into a diet/animal effect and a manure management effect would improve the basis for comparing national NH 3 emission inventories. Graphical abstract Image 1 Highlights • A theoretical framework describes NH 3 N loss and NUE related to animal protein production instead of to raw product. • Animal protein in chicken meat had the highest NUE and the lowest NH3 N losses; the reverse was true for beef. • Differences in NUE and NH3 N losses between countries are mainly explained by manure management. • For beef production differences in manure management and TAN production are both relevant. • Presenting additional metrics than N-lost per animal place would enable a more informed comparison of production systems. [ABSTRACT FROM AUTHOR]

• Iron-based Shape Memory Alloy rebars are available in the construction sector. • They can generate recovery stresses easily due to the shape memory effect. • Hollow Core Slabs structural floors improve their behaviour with continuity. • An active continuity of these structural floors can be achieved with Fe-SMA. • The experimental results ensure an improvement in Service Limit State. Despite the relatively recent introduction of Iron-based Shape-Memory Alloys (Fe-SMA) into structural engineering, more than 150 real applications have been performed to date in Central Europe, especially in retrofitting projects. Thanks to the Shape-Memory Effect, a prestrained and correctly anchored Fe-SMA bar can generate recovery stresses when heated up to 160 °C (activation) or more, and then cooled down. This paper presents research results about using Fe-SMA reinforcing bars as active (prestressed) continuity reinforcement in the hogging bending moment region of Hollow Core Slabs structural floors (HCS-sf). An experimental campaign was designed and carried out on eight HCS-sf specimens, four with concrete topping and four without, and two different slab heights. Using the HCS-sf specimens with the activated Fe-SMA bars resulted in better behaviour in the Service Limit State, which preliminarily proved the effectiveness of the proposed methodology for the specimens with concrete topping, although construction problems arose with the specimens without concrete topping. [ABSTRACT FROM AUTHOR]

With increased digitalization and e-government services, Artificial Intelligence (AI) gained momentum. This paper focuses on AI-governance in Child Social Care field, exploring how aspects of individual, family/community factors are embedded in organizational level, especially when dealing with children resilience and wellbeing. A three-level based review has been conducted. In the first part we explored the interlink between individual factors associated to either resilience or wellbeing are connected to community and governance level where a new conceptual model is provided. In the second phase, we conducted an in-depth systematic literature review using PRISMA review protocol where new categorizations of identified literature with respect to individual, family and community levels in child social care field were suggested, while in the third phase, a review of relevant AI-initiatives in Europe and USA was performed. Finally, a comprehensive discussion of the literature review outcomes was carried out and a new updated conceptual model was provided. • Systematic literature using PRISMA protocol has been carried out. • Athree level literature steps is performed: Management, overall and EU case study reports. • There is a clear distinction between individual and family/community factors in governance. • The sparsity of applications of Artificial Intelligence to child social care is emphasized. • New conceptual models have been put forward. [ABSTRACT FROM AUTHOR]

This study examines the predictive impact of weather conditions and electricity demand on hourly spot prices of emissions allowances during the first three phases of the European Union Emissions Trading System (EU ETS) (2005–2019). We propose an original methodology for constructing European-scale electricity demand and weather indices and characterize the relationship between those indices and emissions allowances prices by means of an advanced predictive modeling technique (Extreme Gradient Boosting). Empirical findings assert that electricity demand and the weather variables under study were of importance for estimating EUA prices during the first three phases of the EU ETS, with air temperature and electricity demand being most relevant to emissions allowances prices. Conversely, total precipitation and relative humidity proved to be the least relevant variables to the outcome. The results also indicate that the relationship between emissions allowances prices and their weather-related predictors was not linear in the studied period. The paper contributes to the growing body of literature on the structural determinants of carbon prices in the EU ETS and enhances our understanding of the impact of climate and weather variability – in the provision of renewable energy production – on the most prominent market-based measure to reduce CO 2 emissions in Europe. [ABSTRACT FROM AUTHOR]

Climate change impacts in one country can lead to impacts in distant locations, for example, via internationally traded crops. Previous work has highlighted a need to include cross-border climate change impacts in climate risk assessments, to describe the exposure and transmission of cross-border climate risk across actors, and understand options for managing this risk. In a case study of the Brazil-Europe soy supply chain, this paper aims to explore how stakeholders perceive past and future shocks, how climate change impacts affect stakeholders differently, and how they might respond. Soy is a key internationally traded commodity and Europe relies on imports for the majority of its soy consumption, used widely in livestock feed. Via 96 semi-structured expert interviews, we found different stakeholder groups are vulnerable to different types of weather shocks, experience different price and supply consequences, and have different capacities to respond. While some responses can reduce risk of impacts across the supply chain (e.g. new soy cultivars, improving transport infrastructure), we also identified examples where responses exacerbate risk for other stakeholders (e.g. export bans, changing demand). A holistic cross-border approach to analysing risk in the soy supply chain can help avoid maladaptation and offer opportunities for more collaborative adaptation. [ABSTRACT FROM AUTHOR]

This paper presents a systematic literature review on both the risks affecting wood supply security and risk mitigation strategies by quantitative and qualitative data analysis. It describes wood-specific supply chain risks, thereupon resulting impacts and counteracting strategies to ensure supply. Risks, impacts, and strategies are documented as basis for a comparative analysis, discussion of results, challenges and research gaps. Finally, the suitability and the limitations of the chosen methodology and the achieved results are discussed. Scanning wood supply chain risks and supply strategies, most of the reviewed papers focus on wood supply for bioenergy generation and only a few studies investigate wood supply chain risk issues for the sawing, wood panel, pulp and paper industries, or biorefineries. This review differs significantly from other reviews in this field as it considers the entire wood value chain including recent studies on new chemical wood-based products and thus provides a more complete picture of the wood-based bioeconomy. Consequently, it contributes to the literature by providing an overarching investigation of the risks affecting wood supply security and possible side effects of a growing wood-based bioeconomy. It was found that comprehensive value chain analyses considering established wood products, large-volume bioenergy products, as well as established and new chemical wood-based products in the context of wood supply security are missing. Studies that map the entire wood value chain with its multilevel interdependences and integrating cascading use of wood are lacking. • Most studies focus on fuelwood supply chain risks affecting bioenergy generation. • Regulations stimulated studies on bioenergy feedstock supply strategies. • Europe especially shows a research topic in securing bioenergy production. • Supply security analyses in the context of the wood supply chain are rare. • Comprehensive analyses of the entire wood value chain are missing. [ABSTRACT FROM AUTHOR]

• A new adjacent accumulation non-homogeneous discrete grey model is proposed. • The proposed model was superior to the other four comparative models. • The consumption of renewable energy throughout Europe and the world was predicted. In this paper, a new adjacent non-homogeneous grey model was proposed to predict renewable energy consumption in Europe. Based on the principle of adjacent accumulation, the proposed model emphasizes the weight relationship between the latest value and the historical data. Meanwhile, the heuristic algorithm is used to optimize the parameters of the proposed model. The model's performance was tested by the examples from four central European countries, including Austria, the Czech Republic, Hungary and Poland. In addition, the consumption of renewable energy in Europe and the world was predicted respectively, which showed that Europe's proportion of the world's renewable energy consumption will gradually decline. [ABSTRACT FROM AUTHOR]

Ionospheric estimation is becoming more and more important for the new multifrequency positioning algorithms, since they can help to improve greatly the convergence time for acquiring a good positioning error. In this paper, an open source tool to estimate precise ionospheric estimates is presented, namely ESA UGI (Unified-GNSS-Ionosphere). The presentation is done jointly with a methodology to test ionospheric model using a modified NeQuick to generate synthetic data. The results with different option of the ESA UGI shows that it has a good performance below 1 TECU (Total Electron Content Units) in vTEC (vertical Total Electron Content) RMS (Root Mean Squared) for European networks, around 2 TECU in a well-covered African region and between 1 and 6 TECU globally with this synthetic data. It shows as well the capability of changing between different ionosphere models (voxel, multilayer and spherical harmonics) and configuration options. Finally, a test with uncombined PPP actual data is presented showing that instantaneous convergence below 30 cm in 3D RMS position error are achievable in a well sounded area in Europe. [ABSTRACT FROM AUTHOR]

The Eco-Management and Audit Scheme (EMAS) is a voluntary Regulation that defines the European Environmental Management System (EMS). Today the EMAS is undergoing a revision process, in order to fit the scheme to organizations and stakeholders’ requirements and increase its diffusion. Italy accounts for roughly 1,000 of the 4,000 certified European organizations and, especially during the last five years, a growing number of organizations have not renewed the certification. Thus, the aim of the survey is to investigate why many Italian organizations have dropped out of EMAS, and to identify which enabling measures would be more effective in order to encourage organizations to move back to the certification. The target of the questionnaire were the 339 Italian organizations that did not renew their EMAS registration between 2010 and 2015, and respondents were 99. In the first part of the paper, we present the general findings, while in the second one, certified Public Administrations and private-owned organizations are compared in order to delineate significant differences between the two groups. Concerning motivations for not renewing EMAS, implementation costs were the key reasons for both groups. Conversely, considering the possible enabling measures, while private-owned organizations demand long term tax benefits, Public Administrations prefer a greater consideration of EMAS in public funding. This paper systematically addresses this phenomenon through a survey, contributing to reduce the existing gap in literature and providing a useful input to decision-makers who are overseeing the EMAS revision process. [ABSTRACT FROM AUTHOR]

Behaviour, practices and culture constitute a powerful human factor in the energy system; in particular the interactions between technologies, practices and norms lock individuals in to certain patterns of (often inefficient) energy use. Consequently, behaviour change has gained traction amongst policymakers as a key area of intervention given the impact energy-related behaviours have on climate change. Given the increasing emphasis within policy perspectives in the European Union, it is surprising that a gap in understanding of the success factors of behaviour change initiatives remains. This paper addresses this gap by identifying and characterising behaviour change initiatives across five European countries (the UK, Ireland, France, Italy, and Spain). The paper provides insights into the success factors and commonly encountered barriers to behaviour change initiatives. Initiatives are classified into 6 broad categories (community-based interventions; information and awareness based interventions; eco-districts; show-case events; energy switching; and smart-technology focused interventions). The results suggest that there are significant knowledge gaps between what is known to work to engage individuals in behavioural change and what is currently being applied in practice. An over-reliance on education and awareness-raising projects is evident, illustrating that such projects do not sufficiently aim for sustained behavioural changes. A dearth of projects incorporating fiscal measures, regulations or legislation to drive behaviour change reflects reluctance on behalf of decision-makers to engage widely with diverse approaches to foster lifestyle change. This paper contributes understandings of the different models and delivery tools employed to change energy-related behaviours; insights into the critical success factors that underpin best practice and the barriers to action; and a ‘what works in practice’ overview of the meaningful approaches to change behaviour. [ABSTRACT FROM AUTHOR]

This paper introduces a participatory Multi-Criteria Assessment (MCA) methodology developed through the Resilience Increasing Strategies for Coasts – Toolkit (RISC-KIT) project and implemented in nine case studies in Europe. The purpose of the MCA was to bridge the disciplinary divide between engineering sciences and social sciences, facilitate the communication and dissemination of local coastal risk assessments and Disaster Risk Reduction (DRR) measures' evaluation to a broad range of actors. The process addressed the importance of integrating scientific knowledge with stakeholders’ knowledge to understand and assess the possible social, political and economic implications of different DRR measures, which could foster or hinder successful implementation. The paper discusses the methodological aspects and implementation of the approach which included visualizing risk reduction of DRR measures using paper-based cards to support interaction and negotiation among participants to select preferred strategic alternatives (SA), and a participatory MCA where stakeholders evaluated the SA against three (self-weighted) criteria: feasibility, acceptability and sustainability. [ABSTRACT FROM AUTHOR]

Recent and historic low-frequency, high-impact events have demonstrated the flood risks faced by exposed coastal areas in Europe and beyond. These coastal zone risks are likely to increase in the future which requires a re-evaluation of coastal disaster risk reduction (DRR) strategies and a new mix of PMP (prevention, e.g., dike protection; mitigation, e.g., limiting construction in flood-prone areas and eco-system based solutions; and preparedness, e.g., Early Warning Systems, EWS) measures. In response to these challenges, the RISC-KIT project has delivered a set of open-source and open-access methods, tools and management approaches to reduce risk and increase resilience to low-frequency, high-impact hydro-meteorological events in the coastal zone (the “RISC-toolKIT”). These products enhance forecasting, prediction and early warning capabilities, improve the assessment of long-term coastal risk and optimise the mix of PMP-measures. In this paper an introduction is provided to the objectives, products, applications and lessons-learned of the RISC-KIT project, which are the subjects of this Special Issue. Subsequent papers provide details on the tools and their application on 10 case study sites in Europe. [ABSTRACT FROM AUTHOR]

The European Space Agency (ESA) has twenty-two Member States with a variety of governance structures and strategic priorities regarding their space activities. The objective of this paper is to provide an up-to date overview and a holistic assessment of the national space governance structures and strategic priorities of the eleven smaller Member States (based on annual ESA contributions). A link is made between the governance structure and the main strategic objectives. The specific needs and interests of small and new Member States in the frame of European Space Integration are addressed. The first part of the paper focuses on the national space governance structures in the eleven smaller ESA Member States. The governance models of these Member States are identified including the responsible ministries and the entities entrusted with the implementation of space strategy/policy and programmes of the country. The second part of this paper focuses on the content and analysis of the national space strategies and indicates the main priorities and trends in the eleven smaller ESA Member States. The priorities are categorised with regards to technology domains, the role of space in the areas of sustainability and the motivators for space investments. In a third and final part, attention is given to the specific needs and interests of the smaller Member States in the frame of European space integration. ESA instruments are tailored to facilitate the needs and interests of the eleven smaller and/or new Member States. [ABSTRACT FROM AUTHOR]