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1. Isolation and complete genome sequencing of the virulent phage vB_EcoS_XY3 infecting multidrug-resistant Escherichia coli.

Author

Fu, Pan, Zhao, Qiang, Shi, Li, Xiong, Qin, Xu, Hongxia, Cai, Senmao, Xu, Qianqian, Sun, Xiaodong, and Sang, Ming

Subjects
*ESCHERICHIA coli, *NUCLEOTIDE sequencing, *BACTERIOPHAGES, *BASE pairs, *BIOLOGICAL pest control agents
Abstract

A virulent phage, named vB_EcoS_XY3, was isolated from hospital wastewater in Xiangyang, China. Its morphological characteristics, growth parameters, adsorption rate, and pH and temperature stability were determined. Phage vB_EcoS_XY3 was found to be able to infect Escherichia coli laboratory strains and also some multidrug-resistant E. coli strains. Its complete genome consists of 51,345 base pairs of double-stranded DNA with an average GC content of 55.24% and 85 putative protein-coding genes. Forty-four genes were annotated with known functions. These results will not only provide further insights into E. coli phages but also have implications for the development of potential biocontrol agents. [ABSTRACT FROM AUTHOR]

Published
2021
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