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The SARS-CoV-2 virus has generated an unprecedented pandemic worldwide for the past 100 years. The healthcare systems have been profoundly challenged by the COVID-19 pandemic; also, tendencies of socio-economic and cultural changes have been observed during this period. One of the professions most affected by this pandemic is dentistry. For dental professionals, the explosion of information available online and through social networks sometimes generates uncertainty and identifying relevant scientific studies and guidelines, which allow the best decisions to be made in the professional activity, can be difficult. The moral obligation of all healthcare providers to care for their patients with the guiding principle of "primum non nocere" is very well known. In this context, national and international guidelines have been developed by accredited professional boards, to correctly inform dental professionals. The purpose of this paper is to identify and highlight the most relevant ethical and safety issues in Romania, which can be applied with confidence during the COVID-19 pandemic, but also in the future, to properly carry out our professional activity and show respect to our patients and to ourselves. [ABSTRACT FROM AUTHOR]

The off-label prescription means that medicines are administered by an unlicensed route, in an unlicensed formulation or dosage or to a child below the stated age range. The use of drugs in an off-label or unlicensed manner to treat children is widespread. Because many prescribed treatments for children have not been adequately tested in children, this population of patients remains a vulnerable one. On the one hand, prescribing off-label use drugs in children determines a lot of controversies but, one the other hand, without this possibility, could be deprived of a chance to be treated. The paper presents the widespread phenomenon of off-label us drugs in children, refl ecting in scientifi c studies in USA and Europe. An important focus is on Romanian statistic of Sildenafi l prescription and on dilemmatic use of it in pediatric cardiology unit. [ABSTRACT FROM AUTHOR]

The new infrastructure for communication has become more and more reliable and used in the past few years. Besides the social communication, science also benefits from the faster Internet services. One of the fields that benefits from the communication over the internet is also the medical field from the communications in research, health care but also in medical education. The authors review the short Internet history starting from 1969 covering over 30 years of continuous evolution. Meanwhile ethic problems emerged and were reported especially by the „Pontifical Council for Social Communications“ but also other organisations.In the second part of the paper the authors present the Internet in use for medical practices and ethical problems that this raises. One of the relations that presents ethical issues are the patient-doctor relation, patient confidentiality, the evolution of the social relation between doctorand his patient, medical commercials, invalidated treatments, plagiarism and others issues. [ABSTRACT FROM AUTHOR]

The paper presents the ethical and methodological issues of the scientific research in children. The ethic requirements for a scientific research are: its importance for health, scientific validity, subjects selection, favourable risk-benefit ratio, independent review, informed consent and respect for the enrolled subjects. Confidentiality is very important for subjects protection. The research Ethics Committees are the forum approveing the research. [ABSTRACT FROM AUTHOR]