The production of new knowledge is configured as one of the main objectives of the implementation of Science, Technology and Innovation policies. At the level of Latin America and Caribbean, the policies that govern and administer science and technology are controlled by secretariats, councils or ministries, who through a budget allocation (investment in P&D) build an STI agenda that seeks, as said, enhance the production of new knowledge. However, there is an important absence in the purposes of implementation, while the conceptual elements of ownership are not considered. This paper analyzes the influence of STI policies on the production and appropriation of STI. The results show the evolution in these two areas in the last 5 years, indicating that, although the production of new knowledge has increased, its appropriation is reduced. [ABSTRACT FROM AUTHOR]