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Virus surveillance and discovery are crucial for virus prediction and outbreak preparedness. Virus samples are frequently bulky and complicated so that effective virus detection remain challenging. Herein, we develop an 3D electrostatic microfluidic platform to rapidly and label-free enrich viruses from bulky samples at low concentrations. The platform consists of double microchannels for streamlining large volume processing and electrodes for enriching viruses by electrostatic interaction. The trajectories of simulation show that particle is successfully enriched under different forces of electrostatic field and different sample flow rates. We demonstrate that the electrostatic microfluidic platform can increase the limit of detection in 100-fold higher based on real-time PCR quantified analysis. Our design thus provides a simple, rapid, label-free and high-throughput viruses concentration platform and would thus have significant utility for various viral detection. The virus samples were injected into the electrostatic microfluidics when the voltage was applied, negative charged viral particles were transferred and collected from the sample channel to the enriching channel under the electrostatic field. [Display omitted] • New electrostatic microfluidic platform to rapidly and label-free enrich viruses. • Simulation and experimental study of electrostatic microfluidic device for high-efficiency virus enrichment. • The 3D device increased the limit of detection in 100-fold higher. • Potential for overcoming the technical barrier in virus surveillance and discovery when samples are bulky and complicated. [ABSTRACT FROM AUTHOR]

Siloxene features abundant functional groups and oxygen vacancies, which facilitates the ultrafine platinum nanoparticles loading for catalyzing hydrogen evolution reaction (HER). Herein, a siloxene-p-Pt-2 h composite has been fabricated with an ultralow platinum loading on siloxene (0.56 wt%), which shows greatly enhanced HER activity featuring an ultralow overpotential (η 10 = 23 mV). Attractively, the siloxene-p-Pt-2 h has been applied as a HER catalyst in a Zn-H 2 O fuel cell, demonstrating a high power density of 157 mW cm−2 in coupling with the cathode hydrogen evolution. Moreover, a coupled configuration between two Zn-H 2 O fuel cells in series and the cell-powered hydroxide electrolyzer achieves the efficient hydrogen co-productions co-catalyzed by the HER catalysts. The excellent HER performance is attributed to the hydrophilic character and the optimal Gibbs free energy via the strong interaction between the siloxene and platinum nanoparticles. This work provides a novel design of self-powered co-productions of hydrogen. Two dimensional siloxene containing abundant functional groups was demonstrated as an effective support to load ultralow platinum nanoparticles (0.56 wt%), which shows superior HER performance in both Zn-H 2 O cells and water electrolysis attributing to the excellent hydrophilia of siloxene and the faster carrier mobility as well as the suitable value of hydrogen Gibbs free energy (ΔG H*). [Display omitted] • A novel strategy to facilely synthesize siloxene-p-Pt catalysts is developed. • Siloxene-p-Pt exhibits excellent HER activity in water splitting and Zn-H 2 O cells. • Hydrogen co-evolutions from Zn-H 2 O cells-powered water splitting is constructed. • The strong electronic interaction and hydrophilia of siloxene enhance HER activity. [ABSTRACT FROM AUTHOR]