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Simple Summary: Breast cancer is a significant cause of female cancer-related deaths in the US. Checking how severe the cancer is helps in planning treatment. Modern AI methods are good at grading cancer, but they are not used much in hospitals yet. We developed and utilized ensemble deep learning algorithms for addressing the tasks of classifying (1) breast cancer subtype and (2) breast cancer invasiveness from whole slide image (WSI) histopathology slides. The ensemble models used were based on convolutional neural networks (CNNs) known for extracting distinctive features crucial for accurate classification. In this paper, we provide a comprehensive analysis of these models and the used methodology for breast cancer diagnosis tasks. Cancer diagnosis and classification are pivotal for effective patient management and treatment planning. In this study, a comprehensive approach is presented utilizing ensemble deep learning techniques to analyze breast cancer histopathology images. Our datasets were based on two widely employed datasets from different centers for two different tasks: BACH and BreakHis. Within the BACH dataset, a proposed ensemble strategy was employed, incorporating VGG16 and ResNet50 architectures to achieve precise classification of breast cancer histopathology images. Introducing a novel image patching technique to preprocess a high-resolution image facilitated a focused analysis of localized regions of interest. The annotated BACH dataset encompassed 400 WSIs across four distinct classes: Normal, Benign, In Situ Carcinoma, and Invasive Carcinoma. In addition, the proposed ensemble was used on the BreakHis dataset, utilizing VGG16, ResNet34, and ResNet50 models to classify microscopic images into eight distinct categories (four benign and four malignant). For both datasets, a five-fold cross-validation approach was employed for rigorous training and testing. Preliminary experimental results indicated a patch classification accuracy of 95.31% (for the BACH dataset) and WSI image classification accuracy of 98.43% (BreakHis). This research significantly contributes to ongoing endeavors in harnessing artificial intelligence to advance breast cancer diagnosis, potentially fostering improved patient outcomes and alleviating healthcare burdens. [ABSTRACT FROM AUTHOR]

Malignancy is the tendency of a medical condition to progressively become fatal and generally refers to the presence of cancerous cells that can spread, invade, and destroy tissues. In the United States, a new cancer diagnosis is given every 30 s, and the rates of diagnosis are not indicating any slowdown. The number of cancer cases is projected to increase by 35% over the next decade. Increasing cancer cases have attracted researchers to find new approaches for their identification and characterization. Skin diseases are a significant healthcare burden, affecting millions of people globally. The early detection and diagnosis of skin diseases are essential to prevent adverse health consequences, including the development of malignant skin tumors. Dermoscopy-based diagnosis of skin diseases is a time-consuming process, particularly in resource-limited healthcare settings. Recent advancements in computer vision algorithms have led to the development of several smartphone-based applications for early skin disease prognosis. In this paper, we have utilized a set of 16 distinctive convolutional neural network models, based on deep learning, to process over 45,000 high-quality images from the HAM10000 dataset, encompassing seven categories of skin diseases. Our models were able to effectively identify and classify skin diseases using lesion images as input. Dermoscopy-based diagnosis of skin diseases is a time-consuming process, particularly in resource-limited healthcare settings. Our proposed application for early skin disease detection aims to prevent unintended health consequences, which can result in wastage of operating hours, resources, and, in some cases, compromised patient health. We have benchmarked our models against one another to evaluate their effectiveness and efficiency, using performance measures such as accuracy, precision, sensitivity, specificity, F-score, and G-Mean. Our results demonstrate that most deployed models achieve an accuracy of up to 99%. [ABSTRACT FROM AUTHOR]