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Simple Summary: Breast cancer is a significant cause of female cancer-related deaths in the US. Checking how severe the cancer is helps in planning treatment. Modern AI methods are good at grading cancer, but they are not used much in hospitals yet. We developed and utilized ensemble deep learning algorithms for addressing the tasks of classifying (1) breast cancer subtype and (2) breast cancer invasiveness from whole slide image (WSI) histopathology slides. The ensemble models used were based on convolutional neural networks (CNNs) known for extracting distinctive features crucial for accurate classification. In this paper, we provide a comprehensive analysis of these models and the used methodology for breast cancer diagnosis tasks. Cancer diagnosis and classification are pivotal for effective patient management and treatment planning. In this study, a comprehensive approach is presented utilizing ensemble deep learning techniques to analyze breast cancer histopathology images. Our datasets were based on two widely employed datasets from different centers for two different tasks: BACH and BreakHis. Within the BACH dataset, a proposed ensemble strategy was employed, incorporating VGG16 and ResNet50 architectures to achieve precise classification of breast cancer histopathology images. Introducing a novel image patching technique to preprocess a high-resolution image facilitated a focused analysis of localized regions of interest. The annotated BACH dataset encompassed 400 WSIs across four distinct classes: Normal, Benign, In Situ Carcinoma, and Invasive Carcinoma. In addition, the proposed ensemble was used on the BreakHis dataset, utilizing VGG16, ResNet34, and ResNet50 models to classify microscopic images into eight distinct categories (four benign and four malignant). For both datasets, a five-fold cross-validation approach was employed for rigorous training and testing. Preliminary experimental results indicated a patch classification accuracy of 95.31% (for the BACH dataset) and WSI image classification accuracy of 98.43% (BreakHis). This research significantly contributes to ongoing endeavors in harnessing artificial intelligence to advance breast cancer diagnosis, potentially fostering improved patient outcomes and alleviating healthcare burdens. [ABSTRACT FROM AUTHOR]

Malignancy is the tendency of a medical condition to progressively become fatal and generally refers to the presence of cancerous cells that can spread, invade, and destroy tissues. In the United States, a new cancer diagnosis is given every 30 s, and the rates of diagnosis are not indicating any slowdown. The number of cancer cases is projected to increase by 35% over the next decade. Increasing cancer cases have attracted researchers to find new approaches for their identification and characterization. Skin diseases are a significant healthcare burden, affecting millions of people globally. The early detection and diagnosis of skin diseases are essential to prevent adverse health consequences, including the development of malignant skin tumors. Dermoscopy-based diagnosis of skin diseases is a time-consuming process, particularly in resource-limited healthcare settings. Recent advancements in computer vision algorithms have led to the development of several smartphone-based applications for early skin disease prognosis. In this paper, we have utilized a set of 16 distinctive convolutional neural network models, based on deep learning, to process over 45,000 high-quality images from the HAM10000 dataset, encompassing seven categories of skin diseases. Our models were able to effectively identify and classify skin diseases using lesion images as input. Dermoscopy-based diagnosis of skin diseases is a time-consuming process, particularly in resource-limited healthcare settings. Our proposed application for early skin disease detection aims to prevent unintended health consequences, which can result in wastage of operating hours, resources, and, in some cases, compromised patient health. We have benchmarked our models against one another to evaluate their effectiveness and efficiency, using performance measures such as accuracy, precision, sensitivity, specificity, F-score, and G-Mean. Our results demonstrate that most deployed models achieve an accuracy of up to 99%. [ABSTRACT FROM AUTHOR]

• More accurate and explanatory model is proposed for natural gas storage deliverability. • A hybrid Sparse Autoencoder and Random Forest model shows on average of 5.7% increase in prediction accuracy. • The first use of machine learning and explanatory methods (XAI) in deliverability prediction for natural gas storage. Numerous subsurface factors, including geology and fluid properties, can affect the connectivity of the storage spaces in depleted reservoirs; hence, fluid flow simulations become more complicated, and predicting their deliverability remains challenging. This paper applies Machine Learning (ML) techniques to predict the deliverability of underground natural gas storage (UNGS) in depleted reservoirs. First, three baseline models were developed based on Support Vector Regression (SVR), Artificial Neural Network (ANN), and Random Forest (RF) algorithms. To improve the accuracy of the RF model as the best-performing baseline model, a unified framework, referred to as SARF, was developed. SARF combines the capabilities of Sparse Autoencoder (SA) and that of Random Forest (RF). To achieve this, the internal representations of the SA, which constitute extracted features of the input variables, are used in RF to develop the proposed SARF framework. The predictive capabilities of the baseline models and the proposed SARF model were validated using 3744 real-world storage data samples of 52 active storage reservoirs in the United States. The experimental result of this study shows that the proposed SARF model achieved an average 5.7% increase in accuracy on four separate data partitions over the baseline RF model. Furthermore, a set of eXplainable Artificial Intelligence (XAI) methods were developed to provide an intuitive explanation of which factors influence the deliverability of reservoir storage. The visualizations developed using the XAI method provide an easy-to-understand interpretation of how the SARF model predicted the deliverability values for separate reservoirs. [ABSTRACT FROM AUTHOR]

Heavy-duty trucks contribute approximately 20% of fuel consumption in the United States of America (USA). The fuel economy of heavy-duty vehicles (HDV) is affected by several real-world parameters like road parameters, driver behavior, weather conditions, and vehicle parameters, etc. Although modern vehicles comply with emissions regulations, potential malfunction of the engine, regular wear and tear, or other factors could affect vehicle performance. Predicting fuel consumption per trip based on dynamic on-road data can help the automotive industry to reduce the cost and time for on-road testing. Data modeling can easily help to diagnose the reason behind fuel consumption with a knowledge of input parameters. In this paper, an artificial neural network (ANN) was implemented to model fuel consumption in modern heavy-duty trucks for predicting the total and instantaneous fuel consumption of a trip based on very few key parameters, such as engine load (%), engine speed (rpm), and vehicle speed (km/h). Instantaneous fuel consumption data can help to predict patterns in fuel consumption for optimized fleet operations. In this work, the data used for modeling was collected at a frequency of 1Hz during on-road testing of modern heavy-duty vehicles (HDV) at the West Virginia University Center for Alternative Fuels Engines and Emissions (WVU CAFEE) using the portable emissions monitoring system (PEMS). The performance of the artificial neural network was evaluated using mean absolute error (MAE) and root mean square error (RMSE). The model was further evaluated with data collected from a vehicle on-road trip. The study shows that artificial neural networks performed slightly better than other machine learning techniques such as linear regression (LR), and random forest (RF), with high R-squared (R2) and lower root mean square error. [ABSTRACT FROM AUTHOR]