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Simple Summary: Melanoma is the most dangerous type of skin cancer worldwide. Early detection of melanoma is crucial for better outcomes, but this often can be challenging. This research explores the use of artificial intelligence (AI) techniques combined with non-invasive imaging methods to improve melanoma detection. The authors aim to evaluate the current state of AI-based techniques using tools including dermoscopy, optical coherence tomography (OCT), and reflectance confocal microscopy (RCM). The findings demonstrate that several AI algorithms perform as well as or better than dermatologists in detecting melanoma, particularly in the analysis of dermoscopy images. This research highlights the potential of AI to enhance diagnostic accuracy, leading to improved patient outcomes. Further studies are needed to address limitations and ensure the reliability and effectiveness of AI-based techniques. Background: Melanoma, the deadliest form of skin cancer, poses a significant public health challenge worldwide. Early detection is crucial for improved patient outcomes. Non-invasive skin imaging techniques allow for improved diagnostic accuracy; however, their use is often limited due to the need for skilled practitioners trained to interpret images in a standardized fashion. Recent innovations in artificial intelligence (AI)-based techniques for skin lesion image interpretation show potential for the use of AI in the early detection of melanoma. Objective: The aim of this study was to evaluate the current state of AI-based techniques used in combination with non-invasive diagnostic imaging modalities including reflectance confocal microscopy (RCM), optical coherence tomography (OCT), and dermoscopy. We also aimed to determine whether the application of AI-based techniques can lead to improved diagnostic accuracy of melanoma. Methods: A systematic search was conducted via the Medline/PubMed, Cochrane, and Embase databases for eligible publications between 2018 and 2022. Screening methods adhered to the 2020 version of the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Included studies utilized AI-based algorithms for melanoma detection and directly addressed the review objectives. Results: We retrieved 40 papers amongst the three databases. All studies directly comparing the performance of AI-based techniques with dermatologists reported the superior or equivalent performance of AI-based techniques in improving the detection of melanoma. In studies directly comparing algorithm performance on dermoscopy images to dermatologists, AI-based algorithms achieved a higher ROC (>80%) in the detection of melanoma. In these comparative studies using dermoscopic images, the mean algorithm sensitivity was 83.01% and the mean algorithm specificity was 85.58%. Studies evaluating machine learning in conjunction with OCT boasted accuracy of 95%, while studies evaluating RCM reported a mean accuracy rate of 82.72%. Conclusions: Our results demonstrate the robust potential of AI-based techniques to improve diagnostic accuracy and patient outcomes through the early identification of melanoma. Further studies are needed to assess the generalizability of these AI-based techniques across different populations and skin types, improve standardization in image processing, and further compare the performance of AI-based techniques with board-certified dermatologists to evaluate clinical applicability. [ABSTRACT FROM AUTHOR]

This paper investigates the stochastic optimization problem focusing on developing scalable parallel algorithms for deep learning tasks. Our solution involves a reformation of the objective function for stochastic optimization in neural network models, along with a novel parallel computing strategy, coined the weighted aggregating stochastic gradient descent (WASGD). Following a theoretical analysis on the characteristics of the new objective function, WASGD introduces a decentralized weighted aggregating scheme based on the performance of local workers. Without any center variable, the new method automatically gauges the importance of local workers and accepts them by their contributions. Furthermore, we have developed an enhanced version of the method, WASGD+, by (1) implementing a designed sample order and (2) upgrading the weight evaluation function. To validate the new method, we benchmark our pipeline against several popular algorithms including the state-of-the-art deep neural network classifier training techniques (e.g., elastic averaging SGD). Comprehensive validation studies have been conducted on four classic datasets: CIFAR-100, CIFAR-10, Fashion-MNIST, and MNIST. Subsequent results have firmly validated the superiority of the WASGD scheme in accelerating the training of deep architecture. Better still, the enhanced version, WASGD+, is shown to be a significant improvement over its prototype. [ABSTRACT FROM AUTHOR]

In many machine learning applications and algorithms, the algorithm performance and accuracy are highly dependent on the metric used to measure the distance between different samples. Therefore, learning a distance metric specific to the data can improve these algorithms' performance. This paper proposes an unrestricted deep metric learning framework based on neural networks' interaction for learning metrics in latent space. The proposed method is inspired by generative neural nets (GANs), in which two neural nets are working together to learn true data distribution. In our method, one network plays the role of a supervisor for another network, a feature learning auto-encoder. Its task is to learn transformation to latent space in which data have more meaningful distance and separability. i.e., the supervisor gets the output of the auto-encoder and sends feedback to modify its weights. They interact with each other interleavingly. Several experiments were conducted on four datasets, such as MNIST, GISETTE, Winnipeg Cropland Classification (WCC), and swarm behavior, from different application domains, to evaluate the proposed method's performance. The results show that we can force auto-encoder to learn label information to project data into a latent space with better separability by using our approach. In addition to better class discrimination, the proposed method is far faster than normal auto-encoders during feature learning and has much less training time in the classification phase. [ABSTRACT FROM AUTHOR]