1. Selective determination of L-dopa in the presence of ascorbic acid and uric acid using a 3D graphene foam.
- Author
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Yue, Hong Yan, Zhang, Hong, Huang, Shuo, Gao, Xin, Chang, Jing, Lin, Xuan Yu, Yao, Long Hui, Wang, Li Ping, and Guo, Er Jun
- Subjects
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INDIUM tin oxide , *DIFFERENTIAL pulse code modulation , *ELECTROCHEMISTRY , *CHEMICAL vapor deposition , *ELECTRODE potential - Abstract
Three-dimensional interconnected network graphene foam (GF) was synthesized by chemical vapor deposition. The GF was transferred onto indium tin oxide glass, acting as an electrode for the selective determination of L-dopa in the presence of ascorbic and uric acid. Using differential pulse voltammetry (DPV) method, the oxidation peak current is well linear with L-dopa concentration in the range of 0.05-1 μM with a sensitivity of 2.64 μA μM−1 and in the range of 1-40 μM with a sensitivity of 1.82 μA μM−1. The detection limit of this electrode for L-dopa is about 20 nM. The proposed electrode can also effectively avoid the interference of ascorbic acid and uric acid, making the proposed sensor suitable for the accurate determination of L-dopa in human urine fluids. This electrode will have a wide range of potential application prospect in electrochemical detection. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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