1. Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction.
- Author
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Survase, Shrikant A., Zebroski, Ryan, Bayuadri, Cosmas, Wang, Ziyu, Adamos, Georgios, Nagy, Grigore, and Pylkkanen, Vesa
- Subjects
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BUTANOL , *LIQUID-liquid extraction , *SOLVENTS - Abstract
Highlights • Use of Southern Pine wood sugars is demonstrated for production of solvents. • Fermentation of C6 and C5-rich streams is shown with productivity above 10 g/L/h. • Membrane assisted continuous fermentation is demonstrated for solvent production. • Use of butyl butyrate as an extractant for solvent extraction demonstrated. • Raffinate after solvent extraction was recycled back without any toxicity issues. Abstract The aim of this work was to demonstrate an industrially relevant pilot scale integrated process to produce butanol and other solvents from lignocellulosic sugars produced with AVAP® biomass fractionation technology from southern pine wood. The concentrated sugars were concurrently fermented using genetically engineered Clostridium acetobutylicum to n-butanol, acetone, isopropanol and ethanol in continuous membrane assisted cell recycle fermentation with steady-state solvent productivity exceeding 10 g/L/h. The solvents from the cell free permeate were recovered with extractant of butyl butyrate in a continuous liquid-liquid extraction column and aqueous product (raffinate) along with unused sugars, nutrients, and metabolic intermediates were recycled back to the fermentors. The total solvent yield approached 0.30 g/g sugars. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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