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In this paper, we establish the existence of standing wave solutions for a class of nonlinear fractional Schrödinger-Poisson system involving nonlinearity with subcritical and critical growth. We suppose that the potential V satisfies either Palais-Smale type condition or there exists a bounded domain Ω such that V has no critical point in ∂ Ω . To overcome the "lack of compactness" of the problem, we combine Del Pino-Felmer's penalization technique with Moser's iteration method and some ideas from Alves [1]. [ABSTRACT FROM AUTHOR]

This study aimed to investigate the probable existence of a causal relationship between sleep phenotypes and proliferative diabetic retinopathy (PDR). Single nucleotide polymorphisms associated with sleep phenotypes were selected as instrumental variables at the genome-wide significance threshold (P < 5 × 10−8). Inverse‐variance weighted was applied as the primary Mendelian randomization (MR) analysis method, and MR Egger regression, weighted median, simple mode, and weighted mode methods were used as complementary analysis methods to estimate the causal association between sleep phenotypes and PDR. Results indicated that genetically predicted sleep phenotypes had no causal effects on PDR risk after Bonferroni correction (P = 0.05/10) [Chronotype: P = 0.143; Daytime napping: P = 0.691; Daytime sleepiness: P = 0.473; Insomnia: P = 0.181; Long sleep duration: P = 0.671; Morning person:P = 0.113; Short sleep duration: P = 0.517; Obstructive sleep apnea: P = 0.091; Sleep duration: P = 0.216; and snoring: P = 0.014]. Meanwhile, there are no reverse causality for genetically predicted PDR on sleep phenotypes [Chronotype: P = 0.100; Daytime napping: P = 0.146; Daytime sleepiness: P = 0.469; Insomnia: P = 0.571; Long sleep duration: P = 0.779; Morning person: P = 0.040; Short sleep duration: P = 0.875; Obstructive sleep apnea: P = 0.628; Sleep duration: P = 0.896; and snoring: P = 0.047]. This study's findings did not support the causal effect of between sleep phenotypes and PDR. Whereas, longitudinal studies can further verify results validation. [ABSTRACT FROM AUTHOR]

In this work, in situ sol–gel strategy was used to introduce silica gel in polyacrylonitrile (PAN) membrane pores, by which the pore structure of organic solvent nanofiltration (OSN) membrane prepared with thermal crosslinking was maintained well. The chemical structure, microstructure and morphology changes of membrane during sol–gel and thermal crosslinking were systematically studied by FTIR, XPS, XRD and SEM. Benefitting from the introduction of silica gel, the fusion of membrane pore structure during thermal crosslinking was effectively inhibited by supporting the pore with silica gel. Therefore, the permeances of the thermally crosslinked membranes supported by in situ silica gel were greatly improved. Furthermore, the thermally crosslinked membrane showed excellent stability of OSN performance due to the generated ladder structure of membrane during thermal crosslinking. This work showed that in situ silica gel supporting is a promising strategy to stabilize the pore structure of PAN membrane during thermal crosslinking. [ABSTRACT FROM AUTHOR]

This paper investigates Mei symmetry and new adiabatic invariants of the disturbed non-material volumes. A infinitesimal transformation group and the infinitesimal transformations vectors of generators are proposed. The definition of Mei symmetry and the determining equation for the systems are presented. The perturbation to the Mei symmetry and new adiabatic invariants for non-material volumes is employed, two types of Mei adiabatic invariant induced by Mei symmetrical perturbation are obtained. Two theorems on new adiabatic invariants are given, and the corresponding deductions about new exact invariants are derived. An example is given to illustrate the application of the method, the corresponding adiabatic invariants are obtained. The example is verified numerically, and it proofs that the theoretical derivation is correct. [ABSTRACT FROM AUTHOR]

The m6A methylation of mRNA has been demonstrated to interact with the "Reader". YTH domain family is one of the readers containing five members involved in the progression of multiple tumors. The present study aimed to explore the YTH family's role in seventeen cancer types. Data were downloaded from The Cancer Genome Atlas (TCGA) dataset and analyzed by Software R 3.6.3. Using different bioinformatics methods, including analyses of the overall survival (OS) and disease-free survival (DFS), Gene Set Variation Analysis (GSVA) enrichment. Genomics of Drug Sensitivity in Cancer (GDSC), CIBERSORT algorithm, multivariate and lasso cox regression analysis our results reveal that, while the expression of the YTH domain family varies distinctively in different cancer types the expression of YTH family is upregulated in most cancer types, especially in liver cancer, and the liver cancer prediction model established herein includes YTHDF1 and YTHDF2. Therefore, the results of the present study have demonstrated that the YTH domain family has the potential to predict the prognosis of cancer and the sensitivity to immunotherapy. [ABSTRACT FROM AUTHOR]

The m6A methylation of mRNA has been demonstrated to interact with the "Reader". YTH domain family is one of the readers containing five members involved in the progression of multiple tumors. The present study aimed to explore the YTH family's role in seventeen cancer types. Data were downloaded from The Cancer Genome Atlas (TCGA) dataset and analyzed by Software R 3.6.3. Using different bioinformatics methods, including analyses of the overall survival (OS) and disease-free survival (DFS), Gene Set Variation Analysis (GSVA) enrichment. Genomics of Drug Sensitivity in Cancer (GDSC), CIBERSORT algorithm, multivariate and lasso cox regression analysis our results reveal that, while the expression of the YTH domain family varies distinctively in different cancer types the expression of YTH family is upregulated in most cancer types, especially in liver cancer, and the liver cancer prediction model established herein includes YTHDF1 and YTHDF2. Therefore, the results of the present study have demonstrated that the YTH domain family has the potential to predict the prognosis of cancer and the sensitivity to immunotherapy. [ABSTRACT FROM AUTHOR]

Graphene oxide (GO)—polyvinyl alcohol (PVA) mixed matrix membranes (MMMs) were prepared on the surface of polysulfone (PSF) ultrafiltration basement membrane by the spray coating method for the dehydration of ethanol and isopropanol via pervaporation (PV). PVA has an excellent membrane-forming property and is rich in hydroxyl groups. GO nanosheets can be cross-linked with PVA that enables GO nanosheets to be well dispersed in PVA without interfacial defects. The effects of GO concentration and the size of GO nanosheets on the separation performance of MMMs were investigated. A complete analysis of different mixtures (ethanol/water = 70:30, 80:20, 90:10 and 95:5 wt.%, isopropanol/water = 80:20 wt.%) and different temperatures of mixed solution for the PV performance of GO-PVA MMMs was studied. When the ratio of mGO/mPVA is 2.0%, the GO-PVA MMMs provided the best PV performance for 90 wt% ethanol–water solution at 50 °C. The permeation flux and separation factor of GO-PVA MMMs were 263.01 g/(m2 h) and 115.48, respectively. With the decrease of the size of GO nanosheets, more GO nanosheets enter the PVA matrix, and the PV performance of the GO-PVA MMMs is increased because the GO nanosheets have selective pores and form a cross-linking structure with PVA. For isopropanol–water mixed solution, the separation factor of GO-PVA MMMs was much higher than that for ethanol–water mixed solution at the same experimental condition. [ABSTRACT FROM AUTHOR]

The aim of this study was to identify the exact origin of force sense and identify whether it arises centrally or peripherally. The present study was designed to analyze the effects of short-term fatigue on pinch force sense and the duration of these effects. During the fatigue protocol, twenty (10 men and 10 women; Mage = 22.0 years old) young Chinese participants were asked to squeeze maximally until the pinch grip force decreased to 50% of its maximal due to fatigue. Participants were instructed to produce the target force (10% of maximal voluntary isometric contraction) using the same hand before and after fatigue (immediately, 10, 30, 60, 180, 300 s). The results showed significantly higher absolute error immediately after fatigue (1.22 ± 1.06 N) than before fatigue (0.68 ± 0.34 N), and 60 s (0.76 ± 0.69 N), 180 s (0.67 ± 0.42 N), and 300 s (0.75 ± 0.37 N) after fatigue (all P < 0.05) but with no effect on the variable error (P > 0.05). It was also revealed that there was a significant overestimate of the constant error values before (0.32 ± 0.61 N) and immediately after fatigue (0.80 ± 1.38 N, all P < 0.05), while no significant overestimation or underestimation exceeded 300 s after fatigue (P > 0.05). Our study results revealed that short-term fatigue resulted in a significant decrease in force sense accuracy, but it did not affect force sense consistently; however, force sense accuracy recovered to a certain extent within 10 s and 30 s, whereas it recovered fully within 60 s, and force sense directivity improvement exceeded 300 s after fatigue. The present study shows that the sense of tension (peripherally) is also an important factor affecting force sense. Our study supports the view that the periphery is part of the origin of force sense. [ABSTRACT FROM AUTHOR]

Objectives: Cancer stem cells (CSCs), a small subpopulation of cells with high tumorigenesis and strong intrinsic drug resistance, exhibit self-renewal and differentiation abilities. CSCs play a crucial role in tumor progression, drug resistance, recurrence and metastasis,and conventional therapy is not enough to eradicate them. Therefore, developing novel therapies targeting CSCs to increase drug sensitivity and preventing relapse is essential. The objective of this review is to present nanotherapies that target and eradicate the tumor "seeds". Evidence acquisition: Evidence was collected and sorted from the literature ranging from 2000 to 2022, using appropriate keywords and key phrases as search terms within scientific databases such as Web of Science, PubMed and Google Scholar. Results: Nanoparticle drug delivery systems have been successfully applied to gain longer circulation time, more precise targeting capability and better stability during cancer treatment. Nanotechnology-based strategies that have been used to target CSCs, include (1) encapsulating small molecular drugs and genes by nanotechnology, (2) targeting CSC signaling pathways, (3) utilizing nanocarriers targeting for specific markers of CSCs, (4) improving photothermal/ photodynamic therapy (PTT/PDT), 5)targeting the metabolism of CSCs and 6) enhancing nanomedicine-aided immunotherapy. Conclusion: This review summarizes the biological hallmarks and markers of CSCs, and the nanotechnology-based therapies to kill them. Nanoparticle drug delivery systems are appropriate means for delivering drugs to tumors through enhanced permeability and retention (EPR) effect. Furthermore, surface modification with special ligands or antibodies improves the recognition and uptake of tumor cells or CSCs. It is expected that this review can offer insights into features of CSCs and the exploration of targeting nanodrug delivery systems. [ABSTRACT FROM AUTHOR]

Dust pollution is one of the most severe environmental issues in open pit mines, hindering green mining development. Open pit mine dust has characteristics of multiple dust-generating points, is irregular, influenced by climatic conditions, and has a high degree of distribution with a wide dispersion range in three dimensions. Consequently, evaluating the quantity of dust dispersion and controlling environmental pollution are crucial for supporting green mining. In this paper, dust monitoring above the open pit mine was carried out with an unmanned aerial vehicle (UAV) on board. The dust distribution patterns above the open pit mine were studied in different vertical and horizontal directions at different heights. The results show that the temperature changes less in the morning and more at noon in winter. At the same time, the isothermal layer becomes thinner and thinner as the temperature rises, which makes it easy for dust to spread. The horizontal dust is mainly concentrated at 1300 and 1550 elevations. The dust concentration is polarized at 1350–1450 elevation. The most serious exceedance is at 1400 elevation, with TSP (the concentration of total suspended particulate), PM10 (particulates with aerodynamic diameter < 10 μm), and PM2.5 (particulates with aerodynamic diameter < 2.5 μm) accounting for 188.8%, 139.5%, and 113.8%, respectively. The height is 1350–1450 elevation. Dust monitoring technology carried out by UAV can be applied to the study of dust distribution in the mining field, and the research results can provide reference for other open pit mines. It can also provide a basis for law enforcement part to carry out law enforcement, which has expanded and wide practical application value. [ABSTRACT FROM AUTHOR]

As a UNESCO World Heritage Site, the Grand Canal of China has a rich intangible cultural heritage along its route. The intangible cultural heritage of folk songs is an important representative. The study of its distribution characteristics and influencing factors is of practical and social significance for promoting the protection and development of intangible cultural heritage in relevant areas and the construction of the Grand Canal Cultural Belt. This paper uses the theories of musicology, geography, sociology, data statistical analysis and spatial analysis to analyze the distribution pattern of intangible cultural heritage items in the Grand Canal basin from the dimensions of geographical space and folk song genre, and from the perspective of natural and social conditions. The results show that the spatial distribution of folk songs in the Grand Canal basin shows a trend of "distribution along the river, two cores and two belts". Water system, landform and regional culture are the main influencing factors for the formation and dissemination of intangible cultural heritage of folk songs. At the same time, compared with the mountainous areas in western China, the economic and social development and frequent population flow in the Grand Canal basin lead to the diversified and unified musical culture characteristics of folk songs. Finally, this paper proposes the suggestions that the folk songs should be integrated into the local social and economic activities. [ABSTRACT FROM AUTHOR]

Epidemiological studies have observed some relationship between psoriasis and celiac disease (CD), while the causal link between these 2 autoimmune diseases was unclear. In the current study, we aimed to explore the causal link between psoriasis and celiac disease with bidirectional 2-sample Mendelian Randomization (MR) study. Eligible instrument variables (IVs) with genome-wide significance (p < 5E−08) were extracted from the summary-level datasets from the published genome-wide association studies (GWAS), which were conducted in the European population. The inverse variance weighted (IVW) method was performed as the main analysis, sensitivity analyses and post-MR analyses were also performed. Our MR analyses found that genetically doubling the odds of CD would increase the risk for psoriasis (p = 1.58e−03, OR [95% CI] 1.232 [1.061–1.432]). And the results were supported by sensitivity analyses. While we found that genetically determined psoriasis was not associated with the risk for CD (IVW: p = 0.985, OR [95% CI] 1.000 [0.965–1.037]). Our study provided novel genetic evidence that patients with CD were at an increased risk of developing psoriasis, while psoriasis was not associated with the risk for CD. Clinicians should be aware of the associations and pay attention to skin manifestations in patients with CD. [ABSTRACT FROM AUTHOR]

Recently, compressed sensing algorithms, including convex optimization and greedy algorithm, are considered as a new development for direction of arrival (DOA) estimation. For the problem of two-dimensional (2-D) DOA estimation, the existing convex optimization-based methods are usually limited by their computational complexity, while the greedy algorithm-based estimation is subjected to its low estimation accuracy. In the current paper, we propose a new 2-D DOA estimation scheme with parallel coprime array. We proposed a modified orthogonal matching pursuit method for the parallel coprime array, which transforms the 2-D DOA estimation into one-dimensional (1-D) DOA estimation to reduce the computation complexity. In addition, the proposed estimation scheme makes full use of the cross-correlation information of the received signal and combines the advantages of the coprime array to achieve a much higher precision with fewer array elements. The simulation results demonstrate the superiority of the proposed algorithm. [ABSTRACT FROM AUTHOR]

The purpose of this study is to evaluate the relationship between preoperative physical performance (grip strength, gait speed, timed up and go) and postoperative pulmonary complications (PPCs) in patients who have undergone coronary artery bypass grafting (CABG). From September 2019 to August 2021, a total of 497 CABG patients who met the inclusion criteria of this study were examined for grip strength, 4-m gait speed, and timed up and go (TUG) before CABG surgery. Among them, 438 were included in the final analysis. PPCs were classified according to the operational definition of Kroenke et al. and patients with clinically significant PPCs were included in the data analysis. Logistic regression was utilised to analyse the relationship between physical performance and clinically significant PPCs. Besides, the receiver operating characteristic (ROC) curve was applied to analyse the predictive effect of grip strength, gait speed, and TUG on clinically significant PPCs after the CABG procedure. In total, 103 (23.5%) patients developed clinically significant PPCs after CABG. After making adjustments for the European System for Cardiac Operative Risk Evaluation (EuroSCORE) and confounding factors, we established that low grip/weight (OR 0.510; 95% CI 0.363–0.715), slow gait speed (OR 0.619; 95% CI 0.517–0.741), and prolonged TUG (OR 1.617; 95% CI 1.379–1.895) were all independently correlated with clinically significant PPCs after CABG. The ROC curve analysis indicated that the area under the ROC curve of the integrated model of the three indicators (AUC 0.792 vs. 0.682, 0.754, 0.765) was larger than that of the model with a single indicator. Besides the predictive effect of the integrated model was superior to the models using grip/weight, gait speed, or TUG alone. Physical performance, including grip/weight, gait speed, and TUG, is a predictive factor for PPCs in CABG patients, and can be used in preoperative evaluations to and help improve the management of high-risk patients. [ABSTRACT FROM AUTHOR]

This paper is devoted to the problem of H ∞ filtering for a class of discrete-time singular Markovian jump systems with generally uncertain transition rates. Each transition rate of the jumping process is completely unknown or only the estimated value is known. The objective is to design a H ∞ filter such that the resulting filtering error system is stochastically admissible (regular, causal and stochastically stable) while satisfying a prescribed H ∞ performance γ . Sufficient conditions are derived that can guarantee the filtering error system is H ∞ stochastically admissible. Moreover, explicit expression of the filter gains is obtained by solving a set of strict linear matrix inequalities. Finally, a numerical example is included to illustrate the effectiveness of the proposed method. [ABSTRACT FROM AUTHOR]

A receptor-mediated, active-targeting and glutathione (GSH) turn-on charge-reversal core/shell nanocomplex HA-MEA-s-s-TGA/PAMAM@DOX was constructed to achieve increased stability, improved cellular uptake, facilitated endo-lysosomal escape and enhanced antitumor efficacy. This nanocomplex was composed of anionic hyaluronic acid (HA)-graft GSH-sensitive HA-MEA-s-s-TGA as the outer shell and the cationic PAMAM@DOX core with encapsulated doxorubicin (DOX) into the hydrophobic cavities of polyamidoamine (PAMAM) dendrimers. We hypothesized that the anionic outer layer could promote cellular uptake of HA-MEA-s-s-TGA/PAMAM@DOX by HA receptor-mediated endocytosis. After internalization into tumor cells, the outer shell of the internalized nanocomplex was disassembled in endo-lysosomes via the destruction of disulfide linkages to re-expose PAMAM drug core. This action induced release of the encapsulated DOX and facilitated endo-lysosomal escape through the synergistic action of the proton sponge effect and cationic–anionic interaction between protonated PAMAM and endo-lysosome membranes. In vitro release profiles demonstrated the intracellular environment-responsive release behavior of DOX from this nanocomplex, with a cumulative release of 80% within 4 days in a simulated tumor intracellular microenvironment, whereas the surface charge changed from − 18.82 mV to + 10.95 mV. The MTT assay revealed the good biocompatibility of the negatively charged nanocomplex and efficient toxicity against HeLa cells. The designed pH/GSH dual-responsive nanocomplex could be an efficacious and safe delivery platform for cancer therapy. [ABSTRACT FROM AUTHOR]

This study aims to explore and compare a novel deep learning-based quantification with the conventional semi-quantitative computed tomography (CT) scoring for the serial chest CT scans of COVID-19. 95 patients with confirmed COVID-19 and a total of 465 serial chest CT scans were involved, including 61 moderate patients (moderate group, 319 chest CT scans) and 34 severe patients (severe group, 146 chest CT scans). Conventional CT scoring and deep learning-based quantification were performed for all chest CT scans for two study goals: (1) Correlation between these two estimations; (2) Exploring the dynamic patterns using these two estimations between moderate and severe groups. The Spearman's correlation coefficient between these two estimation methods was 0.920 (p < 0.001). predicted pulmonary involvement (CT score and percent of pulmonary lesions calculated using deep learning-based quantification) increased more rapidly and reached a higher peak on 23rd days from symptom onset in severe group, which reached a peak on 18th days in moderate group with faster absorption of the lesions. The deep learning-based quantification for COVID-19 showed a good correlation with the conventional CT scoring and demonstrated a potential benefit in the estimation of disease severities of COVID-19. [ABSTRACT FROM AUTHOR]

Furan, which has been identified as possibly carcinogenic for humans, can be induced to different food items by thermal treatment. In accordance with the previous studies and risks associated with prevalence of furan in food, it is necessary to be acknowledged of amounts of furan formed in different thermally processed foods for human awareness. In this study, Headspace Solid-Phase Microextraction Gas Chromatography–Mass Spectrometry (HS-SPME-GC/MS) was optimized for simultaneous determination of furan, furfural, 2-methylfuran and 2-pentylfuran for the first time from different dried fruits and roasted nuts. The method was proved to be valid for determination of all analytes at 50 °C for 25 min, stirring at 700 rpm and 20% NaCl (W/V) using 50/30 μm divinlybenzene/carboxen/polysimethylsiloxane (DVB/CAR/PDMS) fibre. All analytes were baseline-separated at HP 5-MS column in less than 13 min and obtained results have shown prevalence of furan, furfural and 2-pentylfuran in the studied matrices; however, 2-pentylfuran was more prevalent in the roasted nuts than dried fruits and 2-methylfuran has not shown considerable prevalence in both matrices. Moreover, this method was validated in terms of linearity, precision, recovery, specificity, limit of detection and limit of quantification depending on analytes and sample matrices. Hence, the present method was proved to be highly sensitive, specific and robust with good precision and accuracy and suitable for monitoring these furan derivatives in the studied matrices. [ABSTRACT FROM AUTHOR]

We investigate the impact of power structures on the production and pricing strategies in a decentralized subcontracting assembly system consisting of two suppliers (key supplier and subcontractor) and one manufacturer (assembler). The key supplier, who is also the general contractor, negotiates with the manufacturer and assigns partial component production to the subcontractor. We first identify a single power regime (SPR), in which either the key supplier or the manufacturer determines the wholesale price or the order/production quantity. Under SPR, we consider three power structures, namely, KSA, KAS, and SKA. We find that the assembly system will substantially benefit under KAS. Results show that the subcontracting mechanism between the two suppliers can increase each firm's profit and disperse the bargaining power. Such a decentralization of powers can weaken the horizontal decentralization between the suppliers and improve the system's performance, thereby achieving a win–win situation. Furthermore, we extend our analysis to a dual power regime (DPR), in which the key supplier or the manufacturer decides on price and quantity. We show that the proposed assembly system performs optimally under DPR. Moreover, the system will benefit if the firm that is substantially near the end market makes the centralization decision. Compared with the classical pull and push contract model, the proposed assembly system provides the best performance under DPR. [ABSTRACT FROM AUTHOR]

To reveal the self-coordination mechanism of the fragile ecosystem of alpine tundra, we explored the relationship between soil microorganisms and other elements. On the alpine tundra of the Changbai Mountain, different vegetation types, altitudes and soil properties were selected as driving factors of soil microbial community. Soil microbial community, C- and N-cycling functional microbial and fungal biomass were analyzed. Structural equation model was used to study the control of biotic and abiotic factors in rhizosphere soil microbial community. The results showed that the pH value of soil had the strongest direct impact on the diversity and community structure of soil microorganisms, and had significant correlation with most of the C- and N-cycling functional microbial; organic carbon and vegetation also have strongest direct effect on fungal biomass, but all of them were not main factors influence soil microbial community structure, the elevation was the main controlling factor. In addition, the elevation mainly through indirect action affects the soil microbial community by driving distribution of plant species, soil organic carbon and pH value. This finding highlighted that elevation was the main predictor to determine rhizosphere microbial community structure but not vegetation in alpine tundra of Changbai Mountain. [ABSTRACT FROM AUTHOR]

A question central to the Covid-19 pandemic is why the Covid-19 mortality rate varies so greatly across countries. This study aims to investigate factors associated with cross-country variation in Covid-19 mortality. Covid-19 mortality rate was calculated as number of deaths per 100 Covid-19 cases. To identify factors associated with Covid-19 mortality rate, linear regressions were applied to a cross-sectional dataset comprising 169 countries. We retrieved data from the Worldometer website, the Worldwide Governance Indicators, World Development Indicators, and Logistics Performance Indicators databases. Covid-19 mortality rate was negatively associated with Covid-19 test number per 100 people (RR = 0.92, P = 0.001), government effectiveness score (RR = 0.96, P = 0.017), and number of hospital beds (RR = 0.85, P < 0.001). Covid-19 mortality rate was positively associated with proportion of population aged 65 or older (RR = 1.12, P < 0.001) and transport infrastructure quality score (RR = 1.08, P = 0.002). Furthermore, the negative association between Covid-19 mortality and test number was stronger among low-income countries and countries with lower government effectiveness scores, younger populations and fewer hospital beds. Predicted mortality rates were highly associated with observed mortality rates (r = 0.77; P < 0.001). Increasing Covid-19 testing, improving government effectiveness and increasing hospital beds may have the potential to attenuate Covid-19 mortality. [ABSTRACT FROM AUTHOR]

Urban heat island (UHI) represents important human-induced alterations in local climate that has extensive impacts on urban environments and the well-being of urban residents. Under the background of global warming and rapid urbanization, UHI effects will be greatly enhanced, which will further aggravate urban heatwaves and increase health risks to people therein. Therefore, to take adaptive mitigation measures, it is essential to thoroughly understand the meteorological mechanism responsible for the formation of UHIs. Here, we elucidate the roles of the main meteorological parameters in Shanghai's nocturnal UHI intensity (UHII) using long-term meteorological data from 1979 to 2013. The strongest mean nocturnal UHII values were found in autumn and winter, whereas the weakest UHII was found in summer. This seasonal pattern was associated with dense cloudiness, high relative humidity and precipitation, strong winds, and low atmospheric pressure. Negative relationships between the nocturnal UHII and the cloudiness, wind speed, relative humidity, and precipitation and a positive correlation between the UHII and atmospheric pressure were observed for Shanghai. The interactive effects of the wind speed, cloudiness, and relative humidity on the UHII indicate that a calm, dry, and clear-sky environment was optimal for maximum UHI formation. This study provides insights into the mechanisms governing the formation of UHIs and clarifies the key meteorological factors. In addition, our results support the accurate assessment of future climate change impacts on human health and societies by including the UHII as an important assessment index. [ABSTRACT FROM AUTHOR]

In this paper, the existence of two nontrivial solutions for a fractional problem with critical exponent, depending on real parameters, is established. The variational approach is used based on a local minimum theorem due to G. Bonanno. In addition, a numerical estimate on the real parameters is provided, for which the two solutions are obtained. [ABSTRACT FROM AUTHOR]

Kinases are involved in numerous critical cell signaling processes, and dysregulation in kinase signaling is implicated in many types of human cancers. In this study, we applied a parallel-reaction monitoring (PRM)-based targeted proteomic method to assess kinome reprogramming during melanoma metastasis in three pairs of matched primary/metastatic human melanoma cell lines. Around 300 kinases were detected in each pair of cell lines, and the results showed that Janus kinase 3 (JAK3) was with reduced expression in the metastatic lines of all three pairs of melanoma cells. Interrogation of The Cancer Genome Atlas (TCGA) data showed that reduced expression of JAK3 is correlated with poorer prognosis in melanoma patients. Additionally, metastatic human melanoma cells/tissues exhibited diminished levels of JAK3 mRNA relative to primary melanoma cells/tissues. Moreover, JAK3 suppresses the migration and invasion of cultured melanoma cells by modulating the activities of matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9). In summary, our targeted kinome profiling method provided by far the most comprehensive dataset for kinome reprogramming associated with melanoma progression, which builds a solid foundation for examining the functions of other kinases in melanoma metastasis. Moreover, our results reveal a role of JAK3 as a potential suppressor for melanoma metastasis. [ABSTRACT FROM AUTHOR]

Quantitative inversion of fracture weakness plays an important role in fracture prediction. Considering reservoirs with a set of vertical fractures as horizontal transversely isotropic media, the logarithmic normalized azimuthal elastic impedance (EI) is rewritten in terms of Fourier coefficients (FCs), the 90° ambiguity in the azimuth estimation of the symmetry axis is resolved by judging the sign of the second FC, and we choose the FCs with the highest sensitivity to fracture weakness and present a feasible inversion workflow for fracture weakness, which involves: (1) the inversion for azimuthal EI datasets from observed azimuthal angle gathers; (2) the prediction for the second FCs and azimuth of the symmetry axis from the estimated azimuthal EI datasets; and (3) the estimation of fracture weakness combining the extracted second FCs and azimuth of the symmetry axis iteratively, which is constrained utilizing the Cauchy sparse regularization and the low-frequency regularization in a Bayesian framework. Tests on synthetic and field data demonstrate that the 90° ambiguity in the azimuth estimation of the symmetry axis has been removed, and reliable fracture weakness can be obtained when the estimated azimuth of the symmetry axis deviates less than 30°, which can guide the prediction of fractured reservoirs. [ABSTRACT FROM AUTHOR]

The grinding morphology of metal materials is mainly determined by the geometric interference of abrasive particles, which means the machining marks left by the manufacturing process are the key components of the surface structure. However, few researches have been focused on the spatial structure of the grinding morphology. A general form of areal autocorrelative function (AACF) was proposed to characterize the conventional and ultrasonic-assisted grinding surfaces. Firstly, the 3D surfaces under different machining conditions including the axial ultrasonic-assisted grinding, vertical ultrasonic-assisted grinding, and elliptical ultrasonic-assisted grinding were simulated based on the grinding kinematics analysis. Subsequently, the features of the corresponding autocorrelation functions were analyzed and the expression form was given. Finally, the conventional grinding and axial ultrasonic-assisted grinding tests were performed to validate the AACF form. The results showed that the expression form was generally consistent with both the AACFs of the simulated and measured surfaces. The AACF family proposed in this study may serve as an effective and novel way to describe the spatial characteristics of the grinding especially the ultrasonic-assisted grinding surfaces. [ABSTRACT FROM AUTHOR]

α-Tubulin acetyltransferase 1 (ATAT1) catalyzes acetylation of α-tubulin at lysine 40 in various organisms ranging from Tetrahymena to humans. Despite the importance in mammals suggested by studies of cultured cells, the mouse Atat1 gene is non-essential for survival, raising an intriguing question about its real functions in vivo. To address this question, we systematically analyzed a mouse strain lacking the gene. The analyses revealed that starting at postnatal day 5, the mutant mice display enlarged lateral ventricles in the forebrain, resembling ventricular dilation in human patients with ventriculomegaly. In the mice, ventricular dilation is due to hypoplasia in the septum and striatum. Behavioral tests of the mice uncovered deficits in motor coordination. Birth-dating experiments revealed that neuronal migration to the mutant septum and striatum is impaired during brain development. In the mutant embryonic fibroblasts, we found mild defects in cell proliferation and primary cilium formation. Notably, in these cells, ATAT1 is indispensable for tubulin hyperacetylation in response to high salt, high glucose, and hydrogen peroxide-induced oxidative stress. We investigated the role of ATAT1 in the hematopoietic system using multicolor flow cytometry and found that this system remains normal in the mutant mice. Although tubulin acetylation was undetectable in a majority of mutant tissues, residual levels were detected in the heart, skeletal muscle, trachea, oviduct, thymus and spleen. This study thus not only establishes the importance of ATAT1 in regulating mouse forebrain development and governing tubulin hyperacetylation during stress responses, but also suggests the existence of an additional α-tubulin acetyltransferase. [ABSTRACT FROM AUTHOR]

In this paper, the stability of an elastic column, one end of the column fixed and the other end supported by a spring, is studied under the Euler critical load with Koiter stability theory. The potential energy of the system is written as a functional of tangent angle, and the disturbance quantity is expanded into the Fourier series. The quadratic matrix of second-order variation of potential energy is obtained, and all order principal minor determinants are transformed into elementary expressions. The second-order variation is semi-positive definite. And the stability of the critical point depends on the higher-order variations of potential energy. The results show that the stability of the critical state of the flexible restrained column is related to the relative stiffness of the constraint. The post-buckling behavior is analyzed according to Koiter's initial post-buckling theory. The post-buckling path is upward or downward corresponding to stable or unstable equilibrium, respectively. The critical loads of stability and instability under different relative stiffness values are solved accurately. [ABSTRACT FROM AUTHOR]

1000, 1100 and 1150 °C isothermal sections of the Ti-Al-Nb system were studied using x-ray diffraction, scanning electron microscopy and electron probe microanalysis. A small island-like region of single β0 is present at 1000, but absent at 1100 and 1150 °C. γ1 is not a stable phase at 1000 and 1150 °C. Three three-phase fields (α2 + β0 + σ, β0 + σ + γ and α2 + β0 + γ) are identified in the 1000 °C isothermal section (30-60 at.% Ti content). The 1100 °C isothermal section is firstly studied completely. It includes six three-phase and thirteen two-phase fields. Two three-phase fields β + α2 + γ and β + σ + γ are identified in the isothermal section (30-60 at.% Ti content) at 1150 °C. These data are helpful to the fabrication of the TiAl and Ti2AlNb intermetallics. [ABSTRACT FROM AUTHOR]

Macromolecular binding is a complex process that involves sensing and approaching the binding partner, adopting the proper orientation, and performing the physical binding. We computationally investigated the role of E-hooks, which are intrinsically disordered regions (IDRs) at the C-terminus of tubulin, on dynein microtubule binding domain (MTBD) binding to the microtubule as a function of the distance between the MTBD and its binding site on the microtubule. Our results demonstrated that the contacts between E-hooks and the MTBD are dynamical; multiple negatively charted patches of amino acids on the E-hooks grab and release the same positively charged patches on the MTBD as it approaches the microtubule. Even when the distance between the MTBD and the microtubule was greater than the E-hook length, the E-hooks sensed and guided MTBD via long-range electrostatic interactions in our simulations. Moreover, we found that E-hooks exerted electrostatic forces on the MTBD that were distance dependent; the force pulls the MTBD toward the microtubule at long distances but opposes binding at short distances. This mechanism provides a "soft-landing" for the MTBD as it binds to the microtubule. Finally, our analysis of the conformational states of E-hooks in presence and absence of the MTBD indicates that the binding process is a mixture of the induced-fit and lock-and-key macromolecular binding hypotheses. Overall, this novel binding mechanism is termed "guided-soft-binding" and could have broad-reaching impacts on the understanding of how IDRs dock to structured proteins. [ABSTRACT FROM AUTHOR]

In this paper, we investigate two-loop non-planar triangle Feynman integrals involving elliptic curves. In contrast to the Sunrise and Banana integral families, the triangle families involve non-trivial sub-sectors. We show that the methodology developed in the context of Banana integrals can also be extended to these cases and obtain ε-factorized differential equations for all sectors. The letters are combinations of modular forms on the corresponding elliptic curves and algebraic functions arising from the sub-sectors. With uniform transcendental boundary conditions, we express our results in terms of iterated integrals order-by-order in the dimensional regulator, which can be evaluated efficiently. Our method can be straightforwardly generalized to other elliptic integral families and have important applications to precision physics at current and future high-energy colliders. [ABSTRACT FROM AUTHOR]

Introduction: The aim of this work is to evaluate the clinical efficacy and safety of sufentanil vs. remifentanil anesthesia in elderly patients undergoing curative resection for hepatocellular carcinoma (HCC). Methods: Medical records of elderly patients aged ≥ 65 years who received curative resection for HCC between January 2017 and December 2020 were retrospectively reviewed. The patients were divided into either the sufentanil group or the remifentanil group according to the method of analgesia used. Vital signs including mean arterial pressure (MAP), heart rate (HR), and arterial oxygen saturation (SpO2), distribution of T-cell subsets (CD3, CD4, and CD8 lymphocytes), distribution of the stress response index [cortisol (COR), interleukin (IL)-6, C-reactive protein (CRP), and glucose (GLU)] were recorded prior to anesthesia (T0), after induction of anesthesia (T1), at the end of surgery (T2), 24 h after surgery (T3), and 72 h after surgery (T4). Postoperative adverse events were collected. Results: Repeated measure analysis of variance (ANOVA) showed that after controlling for baseline patient demographic and treatment characteristics as covariates, both between- and within-group effects were significant (all P < 0.01), and the interaction between time and treatments was also significant (all P < 0.01) in the vital signs (MAP, HR, and SpO2), distribution of T-cell subsets (CD3, CD4, and CD8 lymphocytes), and distribution of the stress response index (COR, IL-6, CRP, and GLU), indicating that sufentanil led to stable hemodynamic and respiratory functions, lower reduction of T-lymphocyte subsets, and stable stress response indices compared to remifentanil. There is no significant difference in adverse reactions between the two groups (P = 0.72). Conclusions: Sufentanil was associated with improved hemodynamic and respiratory function, less stress response, less inhibition of cellular immunity, and similar adverse reactions compared with remifentanil. [ABSTRACT FROM AUTHOR]

A three-dimensional unified model is proposed to simulate the weld pool dynamic behavior in swing arc narrow gap vertical GMA welding with allowing for swing feature of arc heat source and joint configuration. Both the moving direction of arc and its inclination are considered by transformation of coordinate system. The model can simulate the weld pool sagging process reasonably. Based on the calculated and experimental results, the mechanism of weld formation in swing arc vertical-up welding is studied. The weld pool size and the peak temperature of liquid metal are reduced largely in the case of swing arc, which leads to the faster solidification of weld pool and is the major factor responsible for suppression of weld pool sagging. Meanwhile, upward component of arc force and the enhanced support force from solidified metal bulge benefits the weakness of downward flow of liquid metal. With increasing the swing frequency, weld cross section geometry tends to be symmetrical and weld bead surface becomes smoother. When the swing frequency is higher than 0.6 Hz, the satisfied weld formation can be obtained. [ABSTRACT FROM AUTHOR]

An emerging view regarding cancer-associated fibroblast (CAF) is that it plays a critical role in tumorigenesis and immunosuppression in the tumor microenvironment (TME), but the clinical significance and biological functions of CAFs in non-small cell lung cancer (NSCLC) are still poorly explored. Here, we aimed to identify the CAF-related signature for NSCLC through integrative analyses of bulk and single-cell genomics, transcriptomics, and proteomics profiling. Using CAF marker genes identified in weighted gene co-expression network analysis (WGCNA), we constructed and validated a CAF-based risk model that stratifies patients into two prognostic groups from four independent NSCLC cohorts. The high-score group exhibits a higher abundance of CAFs, decreased immune cell infiltration, increased epithelial–mesenchymal transition (EMT), activated transforming growth factor beta (TGFβ) signaling, and a limited survival rate compared with the low-score group. Considering the immunosuppressive feature in the high-score group, we speculated an inferior clinical response for immunotherapy in these patients, and this association was successfully verified in two NSCLC cohorts treated with immune checkpoint blockades (ICBs). Furthermore, single-cell RNA sequence datasets were used to clarify the molecular mechanisms underlying the aggressive and immunosuppressive phenotype in the high-score group. We found that one of the genes in the risk model, filamin binding LIM protein 1 (FBLIM1), is mainly expressed in fibroblasts and upregulated in CAFs compared to fibroblasts from normal tissue. FBLIM1-positive CAF subtype was correlated with increased TGFβ expression, higher mesenchymal marker level, and immunosuppressive tumor microenvironment. Finally, we demonstrated that FBLIM1 might serve as a poor prognostic marker for immunotherapy in clinical samples. In conclusion, we identified a novel CAF-based classifier with prognostic value in NSCLC patients and those treated with ICBs. Single-cell transcriptome profiling uncovered FBLIM1-positive CAFs as an aggressive subtype with a high abundance of TGFβ, EMT, and an immunosuppressive phenotype in NSCLC. [ABSTRACT FROM AUTHOR]

In this study, a sensitive and facile method with wide linear range and low detection limit for detecting hydrogen sulfide in rat brain microdialysate was developed. The design of the sensor is based on the competitive binding reaction principle, in which cysteine was self-assembly immobilized on the surface of gold electrode, and then the Cu as the electrochemical probe was anchored to the cysteine film through coordination bonding with carboxyl (−COOH) and amino group (−NH) to form the Cu/Cys/Au electrode. The Cu/Cys/Au electrode can serve as an electrochemical HS sensor through a ligand exchange reaction, which may come from the greater affinity of HS than cysteine to the gold surface due to a steric hindrance reason. The hydrogen sulfide cuts off the S-Au bonds between cysteine and Au electrode and leads to the Cu drop off from electrode, resulting in a decrease in the redox signal of Cu, thereby creating a current that is indirectly proportional to the logarithm of the concentration of HS dissolved at the sensor surface. The current response, i.e., signal output, is in wide linearity to logarithm of the concentration of HS in the range of 0.01-100.0 μM with ΔI/μA = 0.0857 lgCHS(nM) +0.124 and very low detection limit 5 nM (S/N = 3). The assay demonstrated here is highly selective with respect to alleviating the interference of other thiol-containing species such as glutathione (GSH), homocysteine (Hcy), and cysteine commonly existing in the brain. The basal level of HS in the microdialysate from the hippocampus of rats is determined to be around 8.6 ± 3.2 μM. The method demonstrated here is facile but reliable and durable and is envisaged to be applicable to understanding the chemical essence involved in physiological and pathological events associated with HS. [ABSTRACT FROM AUTHOR]

Instantaneous frequency (IF) is the most important parameter of a signal, which is an important representation of non-stationary signals, such as frequency-modulated signals. Usually, signals are received with noises. Under noise environment, the conventional IF estimation methods for nonlinear frequency-modulated (NLFM) signal cannot work. In this paper, we focus on how to extract IF of NLFM signal under strong noise environment. First, a modified S-method (SM) is proposed to represent the time-frequency (TF) characteristic. The modified SM uses an adaptive smooth window. The symmetric window is used for multi-component signals and asymmetric window for mono-component signals. The modified SM enhances the TF energy concentration and suppresses the cross-terms effectively. Then, the Viterbi algorithm is used to extract the IF from the TF plane. Viterbi algorithm is a hidden Markov chain approach, which is proposed here as the IF estimator. The proposed method is utilized for various types of NLFM signals. Simulation results demonstrate the efficiency and validity of the proposed method under strong noise environment. [ABSTRACT FROM AUTHOR]

The succession amongst different cyanobacteria genera remains understudied and poorly understood as much of the focus has been on mono-specific blooms. The spring-summer succession between Aphanizomenon flos- aquae and Microcystis and its underlying mechanism were investigated from 2009 to 2012 in hypereutrophic Dianchi Lake in China. Regularly, A. flos- aquae grows rapidly and forms bloom in March at water temperatures around 15°C, followed by Microcystis blooming around 18°C in April. Since 2010, the pattern of succession has changed, featuring an increase of Microcystis but decrease of A. flos- aquae biovolume, leading to near disappearance of A. flos- aquae in 2012. Coincidently, there was a sharp increase of nitrogen concentration in 2010, going up to 5.67 mg/l in 2011, and a big increase in the mass ratio of TN to TP from 13.6 in 2009 to 21.1 in 2011. We hypothesized that temperature is the most influential factor governing the initiation of rapid growth and succession between A. flos- aquae and Microcystis, while increase of TN and/or ratio of TN to TP may trigger the decline and disappearance of A. flos- aquae, time of recruitment, and the population dynamics of Microcystis. Our findings are not only meaningful to the understanding of the cyanobacterial bloom mechanism but also to the management of shallow eutrophic lakes. [ABSTRACT FROM AUTHOR]

Global $C^{0}$ and local $C^{1}$ stability of iterative roots for monotonic functions defined on a compact interval, as well as global $C^{1}$ instability under some assumptions, are well-known facts. In this paper, we investigate the stability of iterative roots for piecewise monotonic functions with nonmonotonicity height equal to 1. We prove the roots are $C^{1}$ locally stable and $C^{0}$ global stable with the same extension. [ABSTRACT FROM AUTHOR]

Microtubules have important functions ranging from maintenance of cell morphology to subcellular transport, cellular signaling, cell migration, and formation of cell polarity. At the organismal level, microtubules are crucial for various biological processes, such as viral entry, inflammation, immunity, learning and memory in mammals. Microtubules are subject to various covalent modifications. One such modification is tubulin acetylation, which is associated with stable microtubules and conserved from protists to humans. In the past three decades, this reversible modification has been studied extensively. In mammals, its level is mainly governed by opposing actions of α-tubulin acetyltransferase 1 (ATAT1) and histone deacetylase 6 (HDAC6). Knockout studies of the mouse enzymes have yielded new insights into biological functions of tubulin acetylation. Abnormal levels of this modification are linked to neurological disorders, cancer, heart diseases and other pathological conditions, thereby yielding important therapeutic implications. This review summarizes related studies and concludes that tubulin acetylation is important for regulating microtubule architecture and maintaining microtubule integrity. Together with detyrosination, glutamylation and other modifications, tubulin acetylation may form a unique 'language' to regulate microtubule structure and function. [ABSTRACT FROM AUTHOR]

Grain boundaries strongly affect many materials properties in polycrystalline materials. However, very few structure-property models exist for grain boundaries, due in large part to the complicated and poorly understood way in which the properties of grain boundaries vary with their crystallographic structure. In the present work, we infer grain boundary structure-property correlations from measurements of the effective properties of a polycrystal. We refer to this approach as grain boundary properties localization. We apply this technique to a simple model system of grain boundary diffusivity in a two-dimensional microstructure, and infer the properties of low- and high-angle grain boundaries from the effective diffusivity of the grain boundary network. The generalization and use of these methods could greatly reduce the computational and experimental effort required to establish structure-property correlations for grain boundaries. More broadly, the technique of properties localization could be used to infer the properties of many microstructural constituents in complex microstructures. [ABSTRACT FROM AUTHOR]

Natalisin (NTL) is a conserved neuropeptide, only present in insects, that has been reported to regulate their sexual activity. In this study, we investigated the involvement of NTL in the reproductive behaviors of a major invasive pest, Spodoptera frugiperda. We identified NTL precursor-encoded transcripts, and evaluated their transcript levels in different stages and tissues of S. frugiperda. The results showed that the NTL transcript level was expressed in both male and female pupae and both male and female adults in the later stage. It was highly expressed in male pupae, 3-day-old male and female adults, and 5-day-old male adults. In different tissues, the expression level is higher in the male and female adult brain and male testis. Immunohistochemical staining of the brain of S. frugiperda female and male adults revealed that three pairs of brain neurons of S. frugiperda adults of both sexes secreted and expressed NTL. To study the role of NTL in reproductive behaviors, NTL was silenced in S. frugiperda male and female adults by RNA interference (RNAi) technology, the results showed that silencing NTL could significantly affect the sexual activity behavior of the adults, reducing the calling rate of females, the courtship rate of males, and the mating rate. In summary, this study emphasizes the important role of NTL in regulating the mating behavior and sexual activity of S. frugiperda in both male and female adults, potentially laying a foundation to employ NTL as a new insect-specific target to control populations of pest insects. [ABSTRACT FROM AUTHOR]

To define the characteristics of fundus manifestations in patients after SARS-CoV-2 infection with multimodal imaging techniques. This is a retrospective multicenter and multimodal imaging study including 90 patients. All patients with a visual complaint occurring immediately after SARS-CoV-2 infection were referred to six clinics between December 2022 and February 2023. Demographic information and the temporal relationship between SARS-CoV-2 infection and visual symptoms were documented. The characteristics of the fundus lesions were evaluated using multimodal imaging. Ninety patients from six hospitals were included in this study, including 24 males (26.67%) and 66 (73.33%) females. Seventy-eight patients (86.66%) (146 eyes) were diagnosed with Acute Macular Neuroretinopathy (AMN). The AMN patients were primarily young women (67.95%). Sixty-eight patients (87.18%) had AMN in both eyes. Thirty-eight eyes (24.36%) included Purtscher or Purtscher-like lesions. optical coherence tomography and infrared retinal photographs can show AMN lesions well. Eleven cases were diagnosed with simple Purtscher or Purtscher-like retinopathy (2 cases, 2.22%), Vogt‒Koyanagi‒Harada (VKH) syndrome or VKH-like uveitis (3 cases, 3.33%), multiple evanescent white-dot syndrome (MEWDS) (2 cases, 2.22%), and rhino-orbital-cerebral mucormycosis (ROCM) (5 cases, 5.56%). After SARS-CoV-2 infection, diversified fundus lesions were evident in patients with visual complaints. In this report, AMN was the dominant manifestation, followed by Purtscher or Purtscher-like retinopathy, MEWDS, VKH-like uveitis, and ROCM. [ABSTRACT FROM AUTHOR]

The aim of this work was to investigate the impact of nanosecond pulse laser drilling on the quality of carbon fiber reinforced polymer (CFRP). The effects of laser parameters, including laser power, scan speed, pulse width and laser frequency on micro-hole quality and the thermal damage generated during the drilling process were analyzed. 0.4 mm diameter micro-holes were drilling using a 1064 nm fiber laser, using univariate and orthogonal experimental method. The results indicate that pumping at the entrance leads to a significant increase in hole diameter and heat-affected zone (HAZ) width at both the entrance and exit, as laser power, pulse width and frequency increase, and scanning speed decrease. The width of the HAZ at the exit is dependent on whether the energy reaches the carbon fiber ablation threshold. The holes were tapered and the hole taper was closely related to the change in laser parameters at the entrance and exit of the hole. A taper of approximately 0.3 was achieved with a combination of 99 W, 50 mm/s, 13 ns and 1500 kHz. The experiments indicate that laser power and pulse width are crucial factors that affect the quality of micro-hole processing. However, nanosecond laser drilling can result in thermal damage defects, including striations, micro-cracks, delamination, voids and surface fiber 'fish scale' peeling. [ABSTRACT FROM AUTHOR]

The sparse triangular solver (SpTRSV) is mostly used for scientific and engineering applications. The structured-grid triangular solver of regular dependencies (STRSV) is a special kind of SpTRSV. Some general SpTRSVs that disregards the regularity of the matrix are unsuitable for solving this problem. This paper proposes an efficient parallel algorithm for STRSV on the SW26010 (a kind of China independently designed many-core processors), namely swStructTRSV. The algorithm makes full use of the fine-grained and low latency communication characteristics of the SW26010 to reduce the waiting time for synchronization, maximizes the regularity of access to improve memory access bandwidth, and achieves overlap between memory access and computation simultaneously. Moreover, the idea of the algorithm can be extended to incomplete LU factorization (ILU factorization) because of consistent dependencies. The experimental results on a core group(8 * 8 network composed of 64 cores) of SW26010 show that swStructTRSV can achieve an average speedup of over 30 in the sequential version. swStructTRSV on SW26010 achieves solving speedups of 2.2 and 6.3 over the fast STRSV (fSpTRSV) previously implemented on SW26010 and MKL on Intel Xeon Gold 6132, respectively. swStructTRSV significantly outperforms cuSparse on NVIDIA TITAN RTX in terms of overall execution time. [ABSTRACT FROM AUTHOR]

It is a challenging and meaningful task to carry out UAV-based livestock monitoring in high-altitude (more than 4500 m on average) and cold regions (annual average – 4 °C) on the Qinghai Tibet Plateau. The purpose of artificial intelligence (AI) is to execute automated tasks and to solve practical problems in actual applications by combining the software technology with the hardware carrier to create integrated advanced devices. Only in this way, the maximum value of AI could be realized. In this paper, a real-time tracking system with dynamic target tracking ability is proposed. It is developed based on the tracking-by-detection architecture using YOLOv7 and Deep SORT algorithms for target detection and tracking, respectively. In response to the problems encountered in the tracking process of complex and dense scenes, our work (1) Uses optical flow to compensate the Kalman filter, to solve the problem of mismatch between the target bounding box predicted by the Kalman filter (KF) and the input when the target detection in the current frame is complex, thereby improving the prediction accuracy; (2) Using a low confidence trajectory filtering method to reduce false positive trajectories generated by Deep SORT, thereby mitigating the impact of unreliable detection on target tracking. (3) A visual servo controller has been designed for the Unmanned Aerial Vehicle (UAV) to reduce the impact of rapid movement on tracking and ensure that the target is always within the field of view of the UAV camera, thereby achieving automatic tracking tasks. Finally, the system was tested using Tibetan yaks on the Qinghai Tibet Plateau as tracking targets, and the results showed that the system has real-time multi tracking ability and ideal visual servo effect in complex and dense scenes. [ABSTRACT FROM AUTHOR]

An amendment to this paper has been published and can be accessed via a link at the top of the paper. [ABSTRACT FROM AUTHOR]

Zeolite/carbon hybrid membranes with enhanced gas permeability were prepared by the incorporation of zeolites Y, β, or ZSM-5 into the precursor of polyamic acid and carbonization at high temperature. The effects of physical and chemical properties of zeolites and the preparation parameters, involving the agglomeration size and crystal diameter of zeolites, content and carbonization temperature, on the related gas separation performances were investigated. Results indicate that embedding the zeolites into carbon membrane can greatly increase the gas permeability of carbon membranes without losing the selectivity obviously. The properties of embedded zeolites and the preparation parameters greatly affect the gas separation performances of derived zeolite/carbon hybrid membranes. The gas permeability and selectivity of derived hybrid carbon membranes can be tuned by optimizing the embedded zeolite properties such as the agglomeration size and crystal diameter, and the preparation parameters such as the zeolite content and carbonization temperature. The effects of incorporating the zeolite into carbon membrane on enhancing the gas permeability might be attributed to the intactly ordered inner pore channels of embedded zeolite, which provides rapid and continuous diffusive routes for gas molecules and interfaced pores formed between the embedded zeolite and carbon matrix, which create new channels for gas diffusion in carbon membranes. [ABSTRACT FROM AUTHOR]

Magnesium alloy shows good ductility and formability in a suitable temperature range, but the spinning of revolution surface workpiece with curved generatrix of magnesium alloy is a complicated problem; multi-pass spinning is low efficiency and needs multiple sets of die, and shear spinning is unsuitable for the formation of curved generatrix revolution surface since the strong thinning may lead to material damage. In this paper, one-pass hot spinning process for magnesium alloy AZ31 sheet is designed and investigated; the effect of the process parameters on the quality of the formed workpiece are analyzed; the minimal wall thickness and the maximal ovality of spun workpiece are taken as evaluating indexes; the process parameters are optimized by orthogonal experimental design based on the finite element simulation on the spinning process. The optimizing results of process parameters have been obtained: diameter-to-thickness ratio of sheet blank is 18, spinning temperature is 300 °C, feed rate is 1.0 mm/r, and swivel angle is 35°. Finally, the validity of the orthogonal experimental design results is demonstrated by one-pass hot spinning experiments. [ABSTRACT FROM AUTHOR]

Based on definition of Riemann-Liouville fractional derivatives, we find that the fractional generalized Hamiltonian system possesses consistent algebraic structure and Lie algebraic structure, and the generalized Poisson conservation law of the fractional generalized Hamiltonian system is investigated. As special cases of this paper, the conditions under which a fractional generalized Hamiltonian system can be reduced to a generalized Hamiltonian system and a classical Hamiltonian system are given, and the Lie algebraic structure and Poisson conservation law of these special dynamical systems are obtained, respectively. Then, by using the method and results of this paper, we construct three kinds of new fractional dynamical model, i.e. a fractional Henon-Heiles model, a fractional Euler-Poinsot model of a rigid body and a fractional Volterra model of the three species groups, and their Poisson conserved quantities are obtained. [ABSTRACT FROM AUTHOR]