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Glaucoma is an eye disease where a loss of vision occurs as a result of progressive optic nerve damage usually associates with high intraocular pressure. A subtype of glaucoma called primary angle-closure glaucoma (PACG) has been observed to be the result of one or more mechanisms such as Pupil block, Plateau iris, Peripheral iris roll, and Lens in the anterior segment of the eye. Reliable features in anterior segment images are important for determining the specific mechanisms involved in PACG. In this paper, first the discriminant features are selected by several feature selection algorithms in the context of PACG detection based on anterior segment optical coherence tomography (AS-OCT) images, and then a novel criteria is proposed to further select more reliable features. Our approach is based on selecting the top-ranked features in each algorithm and its rank combination for selection of the best features. Compared with the features selected by the individual feature selection methods, the features selected by our method achieves the best performance in terms of the accuracy of classification of the four PACG mechanisms by using AdaBoost classifier. [ABSTRACT FROM AUTHOR]

In this paper, we develop a novel feature selection algorithm based on the genetic algorithm (GA) using a specifically devised trace-based separability criterion. According to the scores of class separability and variable separability, this criterion measures the significance of feature subset, independent of any specific classification. In addition, a mutual information matrix between variables is used as features for classification, and no prior knowledge about the cardinality of feature subset is required. Experiments are performed by using a standard lung cancer dataset. The obtained solutions are verified with three different classifiers, including the support vector machine (SVM), the back-propagation neural network (BPNN), and the K-nearest neighbor (KNN), and compared with those obtained by the whole feature set, the F-score and the correlation-based feature selection methods. The comparison results show that the proposed intelligent system has a good diagnosis performance and can be used as a promising tool for lung cancer diagnosis. [ABSTRACT FROM AUTHOR]

We propose an improved model based on LVW embedded model feature extractor and ensemble learning for improving prediction accuracy of hemodialysis timing in this paper. Due to this drawback caused by feature extraction models, we adopt an enhanced LVW embedded model to search the feature subset by stochastic strategy, which can find the best feature combination that are most beneficial to learner performance. In the model application, we present an improved integrated learners for model fusion to reduce errors caused by overfitting problem of the single classifier. We run several state-of-the-art Q&A methods as contrastive experiments. The experimental results show that the ensemble learning model based on LVW has better generalization ability (97.04%) and lower standard error (± 0.04). We adopt the model to make high-precision predictions of hemodialysis timing, and the experimental results have shown that our framework significantly outperforms several strong baselines. Our model provides strong clinical decision support for physician diagnosis and has important clinical implications. [ABSTRACT FROM AUTHOR]