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Diabetes is characterized by constant high level of blood glucose. The human body needs to maintain insulin at very constrict range. The patients who are all affected by diabetes for a long time affected by eye disease called Diabetic Retinopathy (DR). The retinal landmarks namely Optic disc is predicted and masked to decrease the false positive in the exudates detection. The abnormalities like Exudates, Microaneurysms and Hemorrhages are segmented to classify the various stages of DR. The proposed approach is employed to separate the landmarks of retina and lesions of retina for the classification of stages of DR. The segmentation algorithms like Gabor double-sided hysteresis thresholding, maximum intensity variation, inverse surface adaptive thresholding, multi-agent approach and toboggan segmentation are used to detect and segment BVs, ODs, EXs, MAs and HAs. The feature vector formation and machine learning algorithm used to classify the various stages of DR are evaluated using images available in various retinal databases, and their performance measures are presented in this paper. [ABSTRACT FROM AUTHOR]

Artificial intelligence algorithms have been used in a wide range of applications in clinical aided diagnosis, such as automatic MR image segmentation and seizure EEG signal analyses. In recent years, many machine learning-based automatic MR brain image segmentation methods have been proposed as auxiliary methods of medical image analysis in clinical treatment. Nevertheless, many problems regarding precise medical images, which cannot be effectively utilized to improve partition performance, remain to be solved. Due to the poor contrast in grayscale images, the ambiguity and complexity of MR images, and individual variability, the performance of classic algorithms in medical image segmentation still needs improvement. In this paper, we introduce a distributed multitask fuzzy c-means (MT-FCM) clustering algorithm for MR brain image segmentation that can extract knowledge common among different clustering tasks. The proposed distributed MT-FCM algorithm can effectively exploit information common among different but related MR brain image segmentation tasks and can avoid the negative effects caused by noisy data that exist in some MR images. Experimental results on clinical MR brain images demonstrate that the distributed MT-FCM method demonstrates more desirable performance than the classic signal task method. [ABSTRACT FROM AUTHOR]

Blood pressure (BP) is a bio-physiological signal that can provide very useful information regarding human's general health. High or low blood pressure or its rapid fluctuations can be associated to various diseases or conditions. Nowadays, high blood pressure is considered to be an important health risk factor and major cause of various health problems worldwide. High blood pressure may precede serious heart diseases, stroke and kidney failure. Accurate blood pressure measurement and monitoring plays fundamental role in diagnosis, prevention and treatment of these diseases. Blood pressure is usually measured in the hospitals, as a part of a standard medical routine. However, there is an increasing demand for methodologies, systems as well as accurate and unobtrusive devices that will permit continuous blood pressure measurement and monitoring for a wide variety of patients, allowing them to perform their daily activities without any disturbance. Technological advancements in the last decade have created opportunities for using various devices as a part of ambient assisted living for improving quality of life for people in their natural environment. The main goal of this paper is to provide a comprehensive review of various methodologies for continuous cuff-less blood pressure measurement, as well as to evidence recently developed devices and systems for continuous blood pressure measurement that can be used in ambient assisted living applications. [ABSTRACT FROM AUTHOR]

In this paper, we propose a new Internet of Things (IoT) based predictive modelling by using fuzzy cluster based augmentation and classification for predicting the lung cancer disease through continuous monitoring and also to improve the healthcare by providing medical instructions. Here, the fuzzy clustering method is used and which is based on transition region extraction for effective image segmentation. Moreover, Fuzzy C-Means Clustering algorithm is used to categorize the transitional region features from the feature of lung cancer image. In this work, Otsu thresholding method is used for extracting the transition region from lung cancer image. Moreover, the right edge image and the morphological thinning operation are used for enhancing the performance of segmentation. In addition, the morphological cleaning and the image region filling operations are performed over an edge lung cancer image for getting the object regions. In addition, we also propose a new incremental classification algorithm which combines the existing Association Rule Mining (ARM), the standard Decision Tree (DT) with temporal features and the CNN. The experiments have been conducted by using the standard images that are collected from database and the current health data which are collected from patient through IoT devices. The results proved that the performance of the proposed prediction model which is able to achieve the better accuracy when it is compared with other existing prediction model. [ABSTRACT FROM AUTHOR]

We propose an improved model based on LVW embedded model feature extractor and ensemble learning for improving prediction accuracy of hemodialysis timing in this paper. Due to this drawback caused by feature extraction models, we adopt an enhanced LVW embedded model to search the feature subset by stochastic strategy, which can find the best feature combination that are most beneficial to learner performance. In the model application, we present an improved integrated learners for model fusion to reduce errors caused by overfitting problem of the single classifier. We run several state-of-the-art Q&A methods as contrastive experiments. The experimental results show that the ensemble learning model based on LVW has better generalization ability (97.04%) and lower standard error (± 0.04). We adopt the model to make high-precision predictions of hemodialysis timing, and the experimental results have shown that our framework significantly outperforms several strong baselines. Our model provides strong clinical decision support for physician diagnosis and has important clinical implications. [ABSTRACT FROM AUTHOR]

Disease diagnosis from medical images has become increasingly important in medical science. Abnormality identification in retinal images has become a challenging task in medical science. Effective machine learning and soft computing methods should be used to facilitate Diabetic Retinopathy Diagnosis from Retinal Images. Artificial Neural Networks are widely preferred for Diabetic Retinopathy Diagnosis from Retinal Images. It was observed that the conventional neural networks especially the Hopfield Neural Network (HNN) may be inaccurate due to the weight values are not adjusted in the training process. This paper presents a new Modified Hopfield Neural Network (MHNN) for abnormality classification from human retinal images. It relies on the idea that both weight values and output values can be adjusted simultaneously. The novelty of the proposed method lies in the training algorithm. In conventional method, the weights remain fixed but the weights are changing in the proposed method. Experimental performed on the Lotus Eye Care Hospital containing 540 images collected showed that the proposed MHNN yields an average sensitivity and specificity of 0.99 and accuracy of 99.25%. The proposed MHNN is better than HNN and other neural network approaches for Diabetic Retinopathy Diagnosis from Retinal Images. [ABSTRACT FROM AUTHOR]

Meningioma is the one of the most common type of brain tumor, it as arises from the meninges and encloses the spine and the brain inside the skull. It accounts for 30% of all types of brain tumor. Meningioma's can occur in many parts of the brain and accordingly it is named. In this paper, a mixture model based classification of meningioma brain tumor using MRI image is developed. The proposed method consists of four stages. In the first stage, with respect to the cells' boundary, it is necessary to further processing, which ensures the boundary of some cells is a discrete region. Mathematical Morphology brings a fancy result during the discrete processing. Accurate cancer cell nucleus segmentation is necessary for automated cytological image analysis. Thresholding is a crucial step in segmentation..An adaptive binarization technique is an important step for medical image analysis.Finally, a novel hybrid Fuzzy SVM is designed in the classification stage meningioma brain tumor. The tumor classification results of proposed feature extraction with SVM is 74.24%, MM with FSVM is 82.67% and MM with RBF is 62.71% and our proposed method MM with Hybrid SVM is 91.64%. [ABSTRACT FROM AUTHOR]

Skeletal bone age assessment is a widely used standard procedure in both disease detection and growth prediction for children in endocrinology. Conventional manual assessment methods mainly rely on personal experience in observing X-ray images of left hand and wrist to calculate bone age, which show some intrinsic limitations from low efficiency to unstable accuracy. To address these problems, some automated methods based on image processing or machine learning have been proposed, while their performances are not satisfying enough yet in assessment accuracy. Motivated by the remarkable success of deep learning (DL) techniques in the fields of image classification and speech recognition, we develop a deep automated skeletal bone age assessment model based on convolutional neural networks (CNNs) and support vector regression (SVR) using multiple kernel learning (MKL) algorithm to process heterogeneous features in this paper. This deep framework has been constructed, not only exploring the X-ray images of hand and twist but also some other heterogeneous information like race and gender. The experiment results prove its better performance with higher bone age assessment accuracy on two different data sets compared with the state of the art, indicating that the fused heterogeneous features provide a better description of the degree of bones' maturation. [ABSTRACT FROM AUTHOR]

Electrocardiogram (ECG) signal is a process that records the heart rate by using electrodes and detects small electrical changes for each heat rate. It is used to investigate some types of abnormal heart function including arrhythmias and conduction disturbance. In this paper the proposed method is used to classify the ECG signal by using classification technique. First the Input signal is preprocessed by using filtering method such as low pass, high pass and butter worth filter to remove the high frequency noise. Butter worth filter is to remove the excess noise in the signal. After preprocessing peak points are detected by using peak detection algorithm and extract the features for the signal are extracted using statistical parameters. Finally, extracted features are classified by using SVM, Adaboost, ANN and Naïve Bayes classifier to classify the ECG signal database into normal or abnormal ECG signal. Experimental result shows that the accuracy of the SVM, Adaboost, ANN and Naïve Bayes classifier is 87.5%, 93%, 94 and 99.7%. Compared to other classifier naïve bayes classifier accuracy is high. [ABSTRACT FROM AUTHOR]

Multi-label sorting learning has been successful in many fields. It can not only express the complex semantic information of learning objects, but also present good generalization ability in dealing with complex things. This paper proposes age estimation algorithm of facial images based on multi-label sorting. This estimation algorithm is for the lack of facial age dataset, and it changes the traditional multi-valued classification method, simplified the problem of tedious steps to estimate age and shortened the time for model training. A series of experiments on two age datasets shows that the algorithm has achieved very good results in evaluating indicators, and these indicators include MAE (mean absolute error), CS (cumulative score), and convergence rate. When compared with some classic algorithms of age estimation, the efficiency and accuracy of the algorithm are verified. [ABSTRACT FROM AUTHOR]

Eye disease is a major health problem among the elderly people. Cataract and corneal arcus are the major abnormalities that exist in the anterior segment eye region of aged people. Hence, computer-aided diagnosis of anterior segment eye abnormalities will be helpful for mass screening and grading in ophthalmology. In this paper, we propose a multiclass computer-aided diagnosis (CAD) system using visible wavelength (VW) eye images to diagnose anterior segment eye abnormalities. In the proposed method, the input VW eye images are pre-processed for specular reflection removal and the iris circle region is segmented using a circular Hough Transform (CHT)-based approach. The first-order statistical features and wavelet-based features are extracted from the segmented iris circle and used for classification. The Support Vector Machine (SVM) by Sequential Minimal Optimization (SMO) algorithm was used for the classification. In experiments, we used 228 VW eye images that belong to three different classes of anterior segment eye abnormalities. The proposed method achieved a predictive accuracy of 96.96% with 97% sensitivity and 99% specificity. The experimental results show that the proposed method has significant potential for use in clinical applications. [ABSTRACT FROM AUTHOR]

Network virtualization is a vital technology that helps overcome shortcomings such as network ossification of the current Internet architecture. However, virtual network embedding (VNE) involving the allocation of resources for heterogeneous virtual network requests (VNRs) on the substrate network (SN) is considered as NP-hard problem. VNE process may involve conflicting objectives, including energy saving and VNR acceptance rate as the most critical.In this paper, we propose a virtual network multi-objective embedding algorithm based on Q-learning and curiosity-driven (Q-CD-VNE) for improving the performance of the system by optimizing conflicting objectives, namely energy saving and acceptance rate. The proposed algorithm employs Q-learning and curiosity-driven mechanism by considering other non-deterministic factors to avoid falling into a local optimum. The major contributions of this work involve (1) modeling of the multi-objective deterministic factors as binary (0, 1) integer programming problem, (2) formulating the virtual node mapping problem using the Markov decision process (MDP), (3) solving the VNE problem using Q-learning algorithm, (4) mining non-deterministic factors using curiosity-driven mechanism for avoiding prematurely falling into the Exploration-Exploitation dilemma and local optimal. Experimental results in comparison with representative researches in the field prove that the proposed algorithm can reduce energy consumption, improve the request acceptance rate, and improve the long-term average income. [ABSTRACT FROM AUTHOR]

Nature presents an infinite source of inspiration for computational models and paradigms, in particular for researchers associated with the area known as natural computing. The simultaneous optimization of the architectures and weights of artificial neural networks (ANNs) through biologically inspired algorithms is an interesting approach for obtaining efficient networks with relatively good generalization capabilities. This methodology constitutes a concordance between a low structural complexity model and low training error rates. Currently, complexity and high error rates are the leading issues faced in the development of clinical decision support systems (CDSSs) for pregnancy care. Hence, in this paper the use of a biologically inspired technique, known as particle swarm optimization (PSO), is proposed for reducing the computational cost of the ANN-based method referred to as the multilayer perceptron (MLP), without reducing its precision rate. The results show that the PSO algorithm is able to improve computational model performance, showing lower validation error rates than the conventional approach. This technique can select the best parameters and provide an efficient solution for training the MLP algorithm. The proposed nature-inspired algorithm and its parameter adjustment method improve the performance and precision of CDSSs. This technique can be applied in electronic health (e-health) systems as a useful tool for handling uncertainty in the decision-making process related to high-risk pregnancy. The proposed method outperformed, on average, other approaches by 26.4% in terms of precision and 14.9% in terms of the true positive ratio (TPR), and showed a reduction of 35.4% in the false positive ratio (FPR). Furthermore, this method was superior to the MLP algorithm in terms of precision and area under the receiver operating characteristic curve by 2.3 and 10.2%, respectively, when applied to the delivery outcome for pregnant women. [ABSTRACT FROM AUTHOR]

A conference paper about the use of machine learning techniques for rationalizing phenotypic readouts from a rat sleeping model is presented. It informs that the mode of action of small molecules is critical for drug research, both with respect to efficacy and anticipated side effects. It further informs that the machine learning algorithms to derive interpretable rule lists and classification trees for the observed phenotypes have been developed.