650 results
Search Results
2. Treatment of mantle cell lymphoma in Asia: a consensus paper from the Asian Lymphoma Study Group.
- Author
-
Yoon, Dok Hyun, Cao, Junning, Chen, Tsai-Yun, Izutsu, Koji, Kim, Seok Jin, Kwong, Yok Lam, Lin, Tong Yu, Thye, Lim Soon, Xu, Bing, Yang, Deok Hwan, and Kim, Won Seog
- Subjects
- *
MANTLE cell lymphoma , *HEMATOPOIETIC stem cell transplantation , *ASIAN studies - Abstract
Background: Mantle cell lymphoma (MCL) is a B cell malignancy that can be aggressive and with a poor prognosis; the clinical course is heterogeneous. The epidemiology of MCL in Asia is not well documented but appears to comprise 2–6% of all lymphoma cases based on available data, with variation observed between countries. Although international guidelines are available for the treatment of MCL, there is a lack of published data or guidance on the clinical characteristics and management of MCL in patient populations from Asia. This paper aims to review the available treatment and, where clinical gaps exist, provide expert consensus from the Asian Lymphoma Study Group (ALSG) on appropriate MCL management in Asia. Body: Management strategies for MCL are patient- and disease stage-specific and aim to achieve balance between efficacy outcomes and toxicity. For asymptomatic patients with clearly indolent disease, observation may be an appropriate strategy. For stage I/II disease, following international guidelines is appropriate, which include either a short course of conventional chemotherapy followed by consolidated radiotherapy, less aggressive chemotherapy regimens, or a combination of these approaches. For advanced disease, the approach is based on the age and fitness of the patient. For young, fit patients, the current practice for induction therapy differs across Asia, with cytarabine having an important role in this setting. Hematopoietic stem cell transplantation (HSCT) may be justified in selected patients because of the high relapse risk. In elderly patients, specific chemoimmunotherapy regimens available in each country/region are a treatment option. For maintenance therapy after first-line treatment, the choice of approach should be individualized, with cost being an important consideration within Asia. For relapsed/refractory disease, ibrutinib should be considered as well as other follow-on compounds, if available. Conclusion: Asian patient-specific data for the treatment of MCL are lacking, and the availability of treatment options differs between country/region within Asia. Therefore, there is no clear one-size-fits-all approach and further investigation on the most appropriate sequence of treatment that should be considered for this heterogeneous disease. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
3. Qualitative assessment of evidence-informed adolescent mental health policymaking in India: insights from project SAMA.
- Author
-
Ivory, Alice, Arelingaiah, Mutharaju, Janardhana, Navaneetham, Bhola, Poornima, Hugh-Jones, Siobhan, and Mirzoev, Tolib
- Subjects
- *
MENTAL health policy , *MIDDLE-income countries , *PUBLIC officers , *ADOLESCENT health , *RESEARCH personnel - Abstract
Background: The importance of evidence-informed health policymaking is widely recognized. However, many low- and middle-income countries lack evidence-informed mental health policies due to insufficient data, stigma or lack of resources. Various policies address adolescent mental health in India, but published knowledge on their evidence-informed nature is limited. In this paper, we report results of our analysis of the role of evidence in adolescent mental health policymaking in India. Methods: This paper reports findings from the document analysis of key policy documentation (n = 10) and in-depth interviews with policy actors including policymakers, researchers, practitioners and intermediaries (n = 13). Framework analysis was used, informed by the components of a conceptual framework adapted from the literature: actors, policy and evidence processes, nature of evidence itself and contextual influences. Results: Results show that adolescent mental health policies in India were generally evidence-informed, with more key evidence becoming generally available from 2010 onwards. Both formal and informal evidence informed mental health policies, particularly agenda-setting and policy development. Mental health policymaking in India is deemed important yet relatively neglected due to competing policy priorities and structural barriers such as stigma. Use of evidence in mental health policymaking reflected differing values, interests, relative powers and ideologies of policy actors. Involvement of government officials in evidence generation often resulted in successful evidence uptake in policy decisions. Policy actors often favoured formal and quantitative evidence, with a tendency to accept global evidence that aligns with personal values. Conclusions: There is a need to ensure a balanced and complementary combination of formal and informal evidence for policy decisions. Evidence generation, dissemination and use for policy processes should recognize evidence preferences by key stakeholders, while prioritizing locally available evidence where possible. To help this, a balanced involvement of policy actors can ensure complementary perspectives in evidence production and policy agendas. This continued generation and promotion of evidence can also help reduce societal stigma around mental health and promote mental health as a key policy priority. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
4. Moving beyond commitments: creating durable change through the implementation of Asia Pulp and Paper's forest conservation policy.
- Author
-
Dieterich, Urs and Auld, Graeme
- Subjects
- *
NONGOVERNMENTAL organizations , *SUSTAINABLE development , *PAPER industry , *FOREST policy , *FOREST conservation , *SOCIAL responsibility of business - Abstract
Campaigns by non-governmental organizations (NGOs) pressuring companies to adopt sustainability standards have caught academic interest in recent years. Critics of this approach toward increasing biodiversity protection and social justice argue that campaign successes are often short-lived while proponents emphasize the potential of NGO campaigns to achieve positive environmental and social change in the absence of governmental legislation. Focusing on the recent forest conservation policy of Asia Pulp and Paper (APP), a leading pulp and paper company operating in Southeast Asia, we analyze the challenges companies face in implementing sustainability commitments made as a result of NGO and market pressure. Drawing from research on policy implementation and corporate greening we identify key activities to help entrench APP's commitments in the company's operations. Furthermore, we suggest that a range of actions by different stakeholder groups can achieve broader effects of APP's commitments toward better environmental and social stewardship in the region's pulp and paper sector. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
5. Pulp and Paper Market to Grow at USD370.12 Billion by 2028.
- Subjects
- *
PAPER industry forecasting , *BUSINESS forecasting , *PAPER industry & the environment , *PACKAGING materials , *RECYCLABLE material , *CORONAVIRUS diseases - Published
- 2021
6. Pulping Facilities Positioned to be a Key Player to Help Close the Gap in Asia's Reliance on "Smart Fertilizer" Imports.
- Author
-
Begley, Michael and Zabaleta, Carlos M.
- Subjects
- *
FERTILIZER supply & demand , *PULPING , *PAPER mills , *POTASSIUM fertilizers , *MANUFACTURING processes , *SUSTAINABILITY - Published
- 2022
7. PAPER'S CLOSING CHAPTER.
- Author
-
PACHNER, JOANNA
- Subjects
- *
INDUSTRYWIDE conditions , *PAPER industry , *CONSUMPTION (Economics) , *PRINTING paper - Abstract
The article focuses on the decline of the paper industry in the 21st century. There was a significant decrease in printing-paper consumption since the peak in paper demand in North America in 2000. The key challenges facing the sector are boosting the environmental and usability credentials of paper and finding new applications for the pulp. But the consumption decline in the west is not reflected in Asia and South America.
- Published
- 2011
8. State Papers Online Colonial: Asia, Part I: Far East, Hong Kong, and Wei-Hai-Wei.
- Author
-
Hashimoto, Sarah
- Subjects
- *
COLONIES - Abstract
The article reviews the web site State Papers Online Colonial: Asia, Part I: Far East, Hong Kong, and Wei-Hai-Wei at gale.com/c/state-papers-online-colonial-asia-part-i from Gale.
- Published
- 2023
9. MFPANet: Multi-Scale Feature Perception and Aggregation Network for High-Resolution Snow Depth Estimation.
- Author
-
Zhao, Liling, Chen, Junyu, Shahzad, Muhammad, Xia, Min, and Lin, Haifeng
- Subjects
- *
SNOW accumulation , *MICROWAVE remote sensing , *SYNTHETIC aperture radar , *REMOTE-sensing images , *DEPTH perception , *REMOTE sensing , *AVALANCHES - Abstract
Accurate snow depth estimation is of significant importance, particularly for preventing avalanche disasters and predicting flood seasons. The predominant approaches for such snow depth estimation, based on deep learning methods, typically rely on passive microwave remote sensing data. However, due to the low resolution of passive microwave remote sensing data, it often results in low-accuracy outcomes, posing considerable limitations in application. To further improve the accuracy of snow depth estimation, in this paper, we used active microwave remote sensing data. We fused multi-spectral optical satellite images, synthetic aperture radar (SAR) images and land cover distribution images to generate a snow remote sensing dataset (SRSD). It is a first-of-its-kind dataset that includes active microwave remote sensing images in high-latitude regions of Asia. Using these novel data, we proposed a multi-scale feature perception and aggregation neural network (MFPANet) that focuses on improving feature extraction from multi-source images. Our systematic analysis reveals that the proposed approach is not only robust but also achieves high accuracy in snow depth estimation compared to existing state-of-the-art methods, with RMSE of 0.360 and with MAE of 0.128. Finally, we selected several representative areas in our study region and applied our method to map snow depth distribution, demonstrating its broad application prospects. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
10. EMBRACING THE PARADIGM SHIFT OF SUSTAINABLE CONSUMPTION AND PRODUCTION PRACTICES: AN ASIAN PERSPECTIVE FOR A RESILIENT FUTURE.
- Author
-
NAYAK, Smitha, MENDON, Suhan, BIRAU, Ramona, NINULESCU, Petre Valeriu, and CIRJAN, Nadia Tudora
- Subjects
- *
SUSTAINABILITY , *SUSTAINABLE consumption , *PLANNED behavior theory , *ECOLOGICAL modernization ,ECONOMIC conditions in Asia - Abstract
XPLORED, THROUGH A THOROUGH SEARCH STRATEGY IN SCOPUS AND WEB OF SCIENCE WITH KEYWORDS LIKE "SUSTAINABLE CONSUMPTION," "RESPONSIBLE PRODUCTION," AND "SDG 12." AFTER DATA SCREENING, IT WILL SYNTHESIZED AND PRESENTED IN THIS RESEARCH PAPER. TO LAY THE GROUNDWORK FOR WISE POLICY CHOICES AND SUSTAINABLE DEVELOPMENT PROJECTS, THIS RESEARCH PAPER SEEKS TO PROVIDE IMPORTANT INSIGHTS ON THE CONDITION OF RESPONSIBLE CONSUMPTION AND PRODUCTION PRACTICES IN THE POWERFUL ASIAN ECONOMIES OF TODAY. [ABSTRACT FROM AUTHOR]
- Published
- 2024
11. Pandemic potential of henipaviruses.
- Author
-
Wojtkiewicz, Aleksandra, Szota, Maciej, and Kędziora–Kornatowska, Kornelia
- Subjects
- *
HENIPAVIRUSES , *HENDRA virus , *NIPAH virus , *PANDEMICS , *PARAMYXOVIRUSES - Abstract
Introduction and purpose. Hendra and Nipah are two highly dangerous zoonotic viruses belonging to the group of henipaviruses. Although they have been known for over 20 years, no human drug or vaccine has been invented. This paper aims to to describe the epidemiology of the reported paramyxoviruses, the pandemic potential of henipaviruses, and a standardised action plan to counter their spread. This paper reviews scientific articles from 2012-2023 published in scientific databases such as Pubmed, Researchgate, and Google Scholar. The keywords used were pandemic potential of henipaviruses, Hendra virus, Nipah virus, and henipavirus epidemics. State of knowledge description. The mortality rate of henipaviruses varies between 50 and 100%. The Nipah virus is particularly dangerous, with epidemics recurring virtually every year in Asia since 1998. The Hendra virus situation may be manageable because there is an effective vaccine for horses most vulnerable to infection. Due to human activity, the habitats and climate of the animals serving as virus reservoirs are changing. Because of frequent henipavirus outbreaks in Asia and Australia, extensive efforts are being made to contain and neutralise them rapidly. Conclusions. As henipaviruses pose a high pandemic threat, more research into drugs and vaccines is required. It is also essential to develop effective bio-assurance plans, introduce controls on their operation and educate the population on the issue. Reservoir animals, through anthropogenic environmental changes, are changing habitats and feeding sites, making more and more territories vulnerable to the disease. New species of henipaviruses constantly emerge and pose an epizootic challenge to public health. Hence, an essential action is to increase the amount of research into the virus's epidemic development and conduct it as widely as possible. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
12. SBAS-InSAR Based Deformation Monitoring of Tailings Dam: The Case Study of the Dexing Copper Mine No.4 Tailings Dam.
- Author
-
Xie, Weiguo, Wu, Jianhua, Gao, Hua, Chen, Jiehong, and He, Yufeng
- Subjects
- *
TAILINGS dams , *COPPER mining , *DAMS , *DEFORMATIONS (Mechanics) , *DEFORMATION of surfaces , *DEBRIS avalanches , *DAM failures - Abstract
The No.4 tailings pond of the Dexing Copper Mine is the second largest in Asia. The tailing pond is a dangerous source of man-made debris flow with high potential energy. In view of the lack of effective and low-cost global safety monitoring means in this region, in this paper, the time-series InSAR technology is innovatively introduced to monitor the deformation of tailings dam and significant key findings are obtained. First, the surface deformation information of the tailings pond and its surrounding areas was extracted by using SBAS-InSAR technology and Sentinel-1A data. Second, the cause of deformation is explored by analyzing the deformation rate, deformation accumulation, and three typical deformation rate profiles of the representative observation points on the dam body. Finally, the power function model is used to predict the typical deformation observation points. The results of this paper indicated that: (1) the surface deformation of the tailings dam can be categorized into two directions: the upper portion of the dam moving away from the satellite along the Line of Sight (LOS) at a rate of −40 mm/yr, whereas the bottom portion approaching the satellite along the LOS at a rate of 8 mm/yr; (2) the deformation of the dam body is mainly affected by the inventory deposits and the construction materials of the dam body; (3) according to the current trend, deformation of two typical observation points in the LOS direction will reach the cumulative deformation of 80 mm and −360 mm respectively. The research results can provide data support for safety management of No.4 tailings dam in the Dexing Copper Mine, and provide a method reference for monitoring other similar tailings dams. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
13. A New Simplified Visual Assessment Tool Describing Facial Morphotypes Observed and Desired in Asian Populations.
- Author
-
CORDUFF, NIAMH, CHAO, YATES Y. Y., LAM, STEPHANIE C. K., LIM, JOYCE, TING SONG LIM, LOHIA, KIRAN, MANGUBAT, ISABEL, PRASETYO, ADRI, ATCHIMA SUWANCHINA, JE-YOUNG PARK, Chao, Yates Yy, Lam, Stephanie Ck, Lim, Ting Song, Suwanchina, Atchima, and Park, Je-Young
- Subjects
- *
ASIANS , *MASSETER muscle , *ELECTRONIC paper , *MUSCLE growth , *RATIO & proportion - Abstract
OBJECTIVE: A group of established aesthetic physicians sought to develop treatment guidelines for assessing Asian face morphologies that reflect accurate and current beauty standards across Asia. DESIGN: Physicians completed surveys, debated, and voted on their clinical strategies and developed an alternative simplified visual tool of assessment (SVAT) that discerns between country variations in genetic and ideal morphotypes. SETTING: Electronic and paper surveys were followed by consensus debates and voting. PARTICIPANTS: Established aesthetic physicians practicing regularly on Asian patients. MEAUSUREMENTS: A clinically applicable SVAT was developed, which considered facial index, mid-face projection, upper and lower face shape, submalar contour, nose length and dorsal height, eye shape and brow shape, proportion of lips-to-lower face and ratio of upper-to-lower lip, and chin shape. RESULTS: For facial shape change, physicians always assessed the horizontal thirds, facial symmetry, and lip-chin complex profile, and also analyzed overall face shapes and Ogee curves. Criteria for creating oval-shaped faces was also defined and included treating indications, such as loss of angularity and bilateral masseter muscle hypertrophy, narrow jawlines, and longer and wider foreheads. Critical differences and similarities in country-specific aesthetic preferences, treatment requests, and considerations or strategies were uncovered, including the inadequacy of assessing overall peripheral facial shapes. CONCLUSION: This consensus establishes the assessment and treatment criteria for achieving ideal shapes for Asian patients. Specific descriptors are affected by variations; therefore, we present the visual criteria for Asian facial morphotypes. We hope that physicians new to treating Asian patients can use this clinical information to improve their practice. [ABSTRACT FROM AUTHOR]
- Published
- 2020
14. Effects of Dietary Paper Mulberry (Broussonetia papyrifera) on Growth Performance and Muscle Quality of Grass Carp (Ctenopharyngodon idella).
- Author
-
Tang, Tao, Bai, Jinhai, Ao, Zhipeng, Wei, Zehong, Hu, Yi, and Liu, Shaojun
- Subjects
- *
CTENOPHARYNGODON idella , *MULBERRY , *MUSCLE growth , *DIETARY supplements , *MYOSTATIN , *MUSCLES - Abstract
Simple Summary: The quality of muscle plays an important role in improving the economic benefit of aquatic products. The paper mulberry (Broussonetia papyrifera, BP) grows wildly in the south of Asia. In this experiment, grass carps (initial weight: 50.0 ± 0.5 g) were fed diets with the addition of 0%, 5%, 10%, 15% and 20% BP in a control diet (crude protein: 31%, crude fat: 3.8%) for 8 weeks. In conclusion, adding 5% BP did not affect the growth of grass carp. However, the supplementation of 10% BP could improve muscle quality through improving muscle hardness, reducing fat accumulation and muscle fiber diameter, at the cost of reducing growth performance. The present study investigated the effects of dietary paper mulberry (Broussonetia Papyrifera, BP) on growth performance, muscle quality and muscle growth-related mRNA expressions of grass carp. Fish (initial weight: 50.0 ± 0.5 g) were fed diets supplemented with 0% (control diet), 5%, 10%, 15% and 20% BP for 8 weeks. The results showed that increasing levels of paper mulberry linearly and quadratically decreased the special gain rate (SGR) and increased the feed conversion rate (FCR) of grass carp (p < 0.05). Significantly positive quadratic trends were found between paper mulberry levels and muscle crude fat or crude protein of grass carp (p < 0.05). In comparison to the control diet, the 10%BP and 15%BP groups had significantly decreased muscle crude fat and increased crude protein (p < 0.05). The levels of paper mulberry resulted in a linear and quadratic increase in water loss of grass carp muscle (p < 0.05), and all groups with paper mulberry supplementation were significantly higher than the control group (p < 0.05). Significant positive linear and quadratic trends were found between the paper mulberry levels and muscle fiber diameter or density of grass carp (p < 0.05). In comparison to the control diet, the significant differences were found in the 15%BP and 20%BP groups (p < 0.05). The muscle adhesiveness and hardness linearly and quadratically increased with the increasing levels of paper mulberry (p < 0.05), and both of which increased significantly when the level of paper mulberry reached 10% (p < 0.05). In addition, the increase in paper mulberry linearly and quadratically improved the expressions of myoblast determination protein (MyoD), myogenin (MyoG), paired box protein 7 (Pax7) and myostatin 1 (MSTN1) (p < 0.05). When the supplementation of paper mulberry reached 15%, the expressions of all these mRNAs were significantly higher than those of the control group (p < 0.05). In summary, adding 5% paper mulberry did not affect the growth of grass carp. However, the supplementation of 10% paper mulberry could improve muscle quality through improving muscle hardness, reducing fat accumulation and muscle fiber diameter, at the cost of reducing growth performance. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
15. FINANCIAL SYSTEM AND ECONOMIC DEVELOPMENT: A STUDY FOR EMERGING COUNTRIES THROUGH A SYSTEM OF SIMULTANEOUS EQUATIONS.
- Author
-
Warrener, Thomas Cristofaro, Silva, Fernanda Faria, and di Guimarães, Luanna
- Subjects
- *
SIMULTANEOUS equations , *ECONOMIC systems , *ECONOMIC development , *FOREIGN investments , *ECONOMIC expansion ,DEVELOPING countries - Abstract
Objective: The objective of this paper was to analyze the bidirectional relationship between financial development and economic growth for a dataset of Latin American and Asian developing countries between 2001 and 2019. Method: This research employed an empirical approach to analyze the statistical relationship between financial development and economic growth, by presenting an estimation of a system of simultaneous equations for a panel of Asian and Latin American countries using 3SLS. Main Results: The results presented in this research provided evidence that financial development does not appear to have a significant impact on economic growth, although growth appears to have a significant and positive influence on financial development. Moreover, the results also suggested that regulatory quality and domestic credit directed to the private sector have a positive effect on economic growth, while urbanization and education showed a negative influence on growth. The estimated model also indicated that urbanization has a positive influence on financial development while foreign direct investment presented a negative effect on the development of the financial sector. Relevance / Originality: Most of the research agenda on the topic of finance and growth has focused on identifying correlation or causality between these variables, with little attention given to the simultaneous relationship between them. This is still a clear gap in economic literature. Following this premise, the objective of this paper was to analyze the bidirectional relationship between financial development and growth by estimating a system of simultaneous equations using the Zellner and Theil’s (1962) 3SLS methodology. In this sense, the main contribution will be given empirically, based on data and analysis from emerging countries in Latin America and Asia. The fact that financial development has an influence on growth and growth plays a role on the development of the financial sector indicates a simultaneous relationship between these variables. Another relevant contribution is to update the debate on financial systems and economic development for emerging countries, highlighting institutional aspects and financial cycles. Theoretical / Methodological Contributions: The main contribution of this study is in the empirical strategy, whose results dialogue with part of the literature on the financial system and development presented along the text. That is, this research explored the statistical relationship between economic development and financial development for a sample composed by twenty-two Asian and Latin American emerging countries, using a simultaneous equations model. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
16. Fossil energy reduction for heating and cooling of buildings using shallow geothermal integrated energy systems - a comprehensive review.
- Author
-
KUMAR, Balaji
- Subjects
- *
GROUND source heat pump systems , *GEOTHERMAL resources , *FOSSIL fuels , *HEAT sinks , *RENEWABLE energy sources ,DEVELOPING countries - Abstract
Ground source heat pumps (GSHP) are a very efficient system for space heating and cooling, and it was established in 1904. GSHPs can minimize the environmental effect of buildings by using the ground as a renewable energy source. The ground will act as a heat sink or heat source. The research collection aims at finding the various possible opportunities for the effective integration of shallow geothermal energy (SGE) to decrease the fossil energy in the built environment and to reduce emission associated with it. The direct utilization of SGE using a ground source heat pump (GSHP) has been reviewed in detail for global north and global south countries, with a primary focus on heating application. The punctual information of results of various authors have been extensively summarized. This review discusses the GSHP installation status, SGE availability, GSHP system simulation, feasibilities, and performance. Worldwide more than one million GSHP systems have been installed, and the system is prevalent in Europe, the Americas, and Asia. Most of the systems are installed for heating-dominated buildings in the global north. This paper also contains the research details pertaining to the last two decades about refrigerants and compressors for the development of GSHP. Finally, the feasibility study and the performance of the GSHP unit for different climatic conditions are reviewed and it is found that the technique is more feasible for cold and dry climatic conditions. This paper highlights the recent research findings and a potential gap in the above components for further research and development. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
17. Geomorphological Mapping Global Trends and Applications.
- Author
-
Quesada-Román, Adolfo and Peralta-Reyes, Manuel
- Subjects
- *
GEOMORPHOLOGICAL mapping , *BIBLIOMETRICS , *CULTURAL pluralism , *SCIENCE databases , *WEB databases - Abstract
This study conducts a bibliometric analysis of 735 research papers on geomorphological mapping published in English between 2000 and 2021 using the Web of Science database. The analysis focuses on key metrics such as annual publication rates, journal distribution, common keywords, and frequently cited papers. The results demonstrate sustained investment in geomorphological mapping research over the past two decades, driven by advancements in data analysis, GIS technologies, and cross-institutional and cross-country collaboration. While European universities and research centers lead the field, researchers from Latin America and Asia are also making noteworthy contributions. However, research concentration remains largely in Europe, particularly at low altitudes. The study highlights the vital importance of investment in geomorphological mapping research and the benefits of collaboration to advance understanding and knowledge production. It also emphasizes the need for greater geographic and cultural diversity among researchers to ensure a more comprehensive and inclusive approach to research in this field. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
18. Study on the gut symbiotic microbiota in long- and short-winged brown planthopper, Nilaparvata lugens (Stål).
- Author
-
Zhao, Jingjing, Guan, Guangxiang, Li, Danting, Yu, Xiaoping, and Shentu, Xuping
- Subjects
- *
NILAPARVATA lugens , *RICE diseases & pests , *GUT microbiome , *NUCLEOTIDE sequencing , *PEST control - Abstract
The brown planthopper (BPH), Nilaparvata lugens (Stål), is one of the most important rice pests in Asia rice regions. BPH has monophagy, migration, rapid reproduction and strong environmental adaptability, and its control is a major problem in pest management. Adult BPH exhibit wing dimorphism, and the symbiotic microbiota enriched in the gut can provide energy for wing flight muscles as a source of nutrition. In order to study the diversity of symbiotic microbiota in different winged BPHs, this paper takes female BPH as the research object. It was found that the number of symbiotic microbiota of different winged BPHs would change at different development stages. Then, based on the 16S rRNA and ITS sequences, a metagenomic library was constructed, combined with fluorescent quantitative PCR and high-throughput sequencing, the dominant symbiotic microbiota flora in the gut of different winged BPHs was found, and the community structure and composition of symbiotic microbiota in different winged BPHs were further determined. Together, our results preliminarily revealed that symbiotic microbiota in the gut of BPHs have certain effects on wing morphology, and understanding the mechanisms underlying wing morph differentiation will clarify how nutritional factors or environmental cues alter or regulate physiological and metabolic pathways. These findings also establish a theoretical basis for subsequent explorations into BPH-symbiont interplay. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
19. InSAR-DEM Block Adjustment Model for Upcoming BIOMASS Mission: Considering Atmospheric Effects.
- Author
-
Wu, Kefu, Fu, Haiqiang, Zhu, Jianjun, Hu, Huacan, Li, Yi, Liu, Zhiwei, Wan, Afang, and Wang, Feng
- Subjects
- *
SYNTHETIC aperture radar , *STANDARD deviations , *BIOMASS , *DIGITAL elevation models - Abstract
The unique P-band synthetic aperture radar (SAR) instrument, BIOMASS, is scheduled for launch in 2024. This satellite will enhance the estimation of subcanopy topography, owing to its strong penetration and fully polarimetric observation capability. In order to conduct global-scale mapping of the subcanopy topography, it is crucial to calibrate systematic errors of different strips through interferometric SAR (InSAR) DEM (digital elevation model) block adjustment. Furthermore, the BIOMASS mission will operate in repeat-pass interferometric mode, facing the atmospheric delay errors introduced by changes in atmospheric conditions. However, the existing block adjustment methods aim to calibrate systematic errors in bistatic mode, which can avoid possible errors from atmospheric effects through interferometry. Therefore, there is still a lack of systematic error calibration methods under the interference of atmospheric effects. To address this issue, we propose a block adjustment model considering atmospheric effects. Our model begins by employing the sub-aperture decomposition technique to form forward-looking and backward-looking interferograms, then multi-resolution weighted correlation analysis based on sub-aperture interferograms (SA-MRWCA) is utilized to detect atmospheric delay errors. Subsequently, the block adjustment model considering atmospheric effects can be established based on the SA-MRWCA. Finally, we use robust Helmert variance component estimation (RHVCE) to build the posterior stochastic model to improve parameter estimation accuracy. Due to the lack of spaceborne P-band data, this paper utilized L-band Advanced Land Observing Satellite (ALOS)-1 PALSAR data, which is also long-wavelength, to emulate systematic error calibration of the BIOMASS mission. We chose climatically diverse inland regions of Asia and the coastal regions of South America to assess the model's effectiveness. The results show that the proposed block adjustment model considering atmospheric effects improved accuracy by 72.2% in the inland test site, with root mean square error (RMSE) decreasing from 10.85 m to 3.02 m. Moreover, the accuracy in the coastal test site improved by 80.2%, with RMSE decreasing from 16.19 m to 3.22 m. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
20. Long waves of economic growth in Asia and Western Europe, 1950-2020: are there any circularcumulative causation and contradiction aspects?
- Author
-
SAMUDRO, BHIMO R., PRATAMA, YOGI P., SOESILO, ALBERTUS M., BLOCH, HARRY, SALIM, RUHUL, PRASETYO, ANDRI, and SISTRIATMAJA, MUHAMMAD B.
- Subjects
- *
ECONOMIC expansion , *CIRCULAR economy , *FINANCIAL crises , *ECONOMIC indicators , *CONTRADICTION , *ECONOMIC impact - Abstract
This paper discusses some comparative analysis between the pattern of economic performances in Asia and Western Europe during 1950s-2020s through political economies perspective. The Asian and Western European economic performances are investigated through some stylized facts in the sense of economic factors. Three analyses are used to explain the general pattern of these regions. First, this study examines the pattern of GDP growth per capita during the 1950s-2020s, focusing on several countries in this region. Second, the analysis captures the pattern of linkages of economic variables in this region related to the principle of Circular and Cumulative causation (CCC) and contradiction. Third, the analysis employs a historical perspective underpinned by the results in the second analysis. This third analysis is crucial to appreciating Asia's global economic performance and also the process of Western deterioration phenomenon through long wave, including the occurrence recession and financial crises. The institutions of globalization and neoliberalism that put the power of capital promoted a financial crisis several times during the decades of 1980s-2020. The financial crisis is depicted by contradictions in the structural linkages among economic factors in Western Europe over the period. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
21. El futuro ya llegó: repensando los vínculos de América Latina con Asia.
- Author
-
Pedrosa, Fernando
- Subjects
- *
INTERNATIONAL relations , *POLITICAL parties , *INTERREGIONALISM , *WORLD history , *HETEROGENEITY - Abstract
This paper examines the ties between Latin America and Asia by moving beyond the homogenisation of the two regions through elevating the importance of opposition to a third party, in this case an "imperialist" and developed North. In contrast to normative analyses based on outmoded conceptions of world history, it proposes an intellectual exercise that problematises the interregional bond by placing the emphasis on heterogeneities rather than broad bush approaches that ignore the complex and diverse national and regional realities. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
22. An automation solution to convert CAD engineering drawings into railroad station models.
- Author
-
Wang, Yuan, Li, Xiaopeng, and Zhang, Yu
- Subjects
- *
RAILROAD engineering , *ENGINEERING drawings , *MODEL railroad stations , *USER interfaces , *AUTOMATION - Abstract
Creating a high‐fidelity railroad station model to match the physical details of hundreds of tracks and switches is never a trivial task. The manual modeling approach often costs engineers significant efforts and constrains the generality and extensivity of many advanced methods. Taking advantage that many stations are drawn proportionally into two‐dimensional drawing exchange format (DXF) files via state‐of‐the‐art computer‐aided design (CAD) techniques, this paper proposed an efficient solution to convert DXF files into meaningful station models. The proposed solution consists of two phases (1) converting graphic basic primitives without explicit engineering interpretations into recognizable railroad symbols and (2) modeling undirected railroad station graphs with necessary configurations such as endpoints and routes. The proposed solution is developed into a graphic user interface application with minimal user interactions and subsequently tested at several real‐world passenger stations in Asia for its validity, productivity, and applicability. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
23. The Global Decline in Human Fertility: The Post-Transition Trap Hypothesis.
- Author
-
Aitken, Robert John
- Subjects
- *
FERTILITY decline , *HUMAN reproductive technology , *DEMOGRAPHIC transition , *HUMAN fertility , *HUMAN reproduction , *INFERTILITY , *FERTILITY - Abstract
Over the past half a century many countries have witnessed a rapid fall in total fertility rates, particularly in the world's most advanced economies including the industrial powerhouses of Eastern Asia and Europe. Such nations have now passed through the first and second demographic transitions and are currently exhibiting fertility rates well below the replacement threshold of 2.1, with no sign of recovery. This paper examines the factors responsible for driving these demographic transitions and considers their impact on both fertility and fecundity (our fundamental capacity to reproduce). I argue that because the first demographic transition was extremely rapid and largely driven by socioeconomic factors, it has had no lasting impact on the genetic/epigenetic underpinnings of human fecundity. However, the second demographic transition will be different. A series of conditions associated with low fertility societies, including relaxed selection pressure for high-fertility genotypes, the indiscriminate use of assisted reproductive technologies to treat human infertility, and environmental contamination with reproductive toxicants, may impact our genetic constitution in ways that compromise the future fecundity of our species. Since any fundamental change in the genetic foundations of human reproduction will be difficult to reverse, we should actively pursue methods to monitor human fecundity, as sub-replacement fertility levels become established across the globe. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
24. Effects of Different Parts on the Chemical Composition, Silage Fermentation Profile, In Vitro and In Situ Digestibility of Paper Mulberry.
- Author
-
Hao, Yangyi, Huang, Shuai, Liu, Gaokun, Zhang, Jun, Liu, Gang, Cao, Zhijun, Wang, Yajing, Wang, Wei, Li, Shengli, Fondevila, Manuel, and Caroprese, Mariangela
- Subjects
- *
SILAGE , *SILAGE fermentation , *MULBERRY , *FATTY acids , *AMINO acids , *CARBOHYDRATES , *LACTATES - Abstract
Simple Summary: Paper mulberry (Broussonetia papyrifera, PM) is a potential roughage source widely distributed in Asia, but the chemical composition, silage fermentation, and digestibility are not fully understood. Here, we compared the chemical composition, silage fermentation, and digestibility of leaf, stem, and whole plant of PM to evaluate its feeding value. The result showed that the leaf had lower fiber content and higher protein content than the stem and whole plant. Meanwhile, the stem silage had the lowest pH value and lactate content, while those in the leaf were the highest. The in vitro and in situ digestibility showed the leaf was more digestible. Our study gives the reference of different parts of PM to be used as a feedstuff. Paper mulberry (Broussonetia papyrifera, PM) is high protein but unutilized as a feed source. The study explores the different parts (leaf, stem, and whole plant) of PM chemical composition, silage fermentation, and in vitro and in situ digestibility, aiming to give some guidelines to PM usage as feed. The result showed that the leaf had a higher fresh weight than the stem (p < 0.05). The dry matter contents of the three groups had no differences. The highest crude protein, ether extract, water-soluble carbohydrate, ash, calcium, phosphorus, amino acid contents, and butter capacity were observed in the leaf (p < 0.05). The stem had the highest (p < 0.05) neutral detergent fiber, acid detergent fiber, and lignin contents. After ensiling, the stem silage had the lowest pH value, ammonia nitrate (NH3-N), lactate, acetate, and propionate (p < 0.05). The leaf silage had the highest pH value (p < 0.05). The lactate, acetate, and propionate in the leaf and whole plant silage had no difference. The butyrate was not detected in all silage. The in vitro and in situ digestibility experiments showed the leaf had the highest digestibility (p < 0.05), which could produce more volatile fatty acids and have a higher effective digestibility. These results allow a greater understanding of PM to be used as a feedstuff. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
25. High-impact papers from China, Japan, India, and Korea.
- Author
-
Hongling, Fang and Hai-Min, Chang
- Subjects
- *
PERIODICAL publishing , *SCHOLARLY publishing , *PERIODICALS , *PUBLISHING , *DATABASES - Abstract
This paper compares 'high-impact' papers from China, Japan, India and Korea in 2012, together with papers from these countries in Cell, Nature, and Science (CNS) from 2010 to 2012. China leads on 'highly cited' and 'hot' papers in 2012, while Japan has the highest number in CNS (653), followed by China (471), Korea (131) and India (83). Although China published more high-impact papers in 2012, papers published in CNS were at a relatively low level, which appears to show that while some of the research in China is at a relatively high level, this is not entirely reflected in the number of papers in these 'elite' journals. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
26. Tracking Austronesian expansion into the Pacific via the paper mulberry plant.
- Author
-
Matisoo-Smith, Elizabeth A.
- Subjects
- *
PHYLOGEOGRAPHY , *PAPER mulberry , *HUMAN geography - Abstract
The article discusses research on the Austronesian migrations revealed by phylogeography of Pacific paper mulberry. It references a study by C-S Chang et al published in a previous issue. Topics covered include the direct genetic link between Taiwan and one of the Pacific commensal species, the geographic origins of paper mulberry and its spread through Island Southeast Asia and into the Pacific, and Neolithic expansions from the mainland of China to Taiwan.
- Published
- 2015
- Full Text
- View/download PDF
27. Anthelmintic Resistance in Haemonchus contortus of Sheep and Goats from Asia--A Review of In Vitro and In Vivo Studies.
- Author
-
Qamar, Warda and Alkheraije, Khalid Ali
- Subjects
- *
HAEMONCHUS contortus , *FECAL egg count , *SCRAPIE , *SHEEP , *ANTHELMINTICS , *GOATS , *DRUG resistance - Abstract
The potential of Haemonchus contortus is quite impressive to acquire resistance to anthelmintic drugs. Asian field populations of H. contortus are reported to exhibit resistance to most of the anthelmintic drug families, including closantel, imidazothiazoles, macrocyclic lactones and benzimidazoles. This review paper comes up with a comprehensive overview of haemonchosis with anthelmintic resistance (AR), with particular attention to studies conducted in regions of Asia. It also confers the prevalence and mechanisms in H. contortus for anthelmintic resistance, indicating the necessity for alternative approaches to control the pathogen. Several SNPs identified in gene isotype-1 β-tubulin gene have been discussed that are associated with benzimidazole resistance and are prevalent in H. contortus populations in Asia. The methods used by H. contortus to withstand the effects of these medications are examined together with the history of how resistance to different anthelmintics in this species has developed. The approaches for diagnosing resistance are also compiled in this review. Such diagnosis currently largely relies on the fecal egg count reduction test, which has cost and sensitivity issues. Past and present efforts to use less expensive and time-consuming phenotypic assays with free-living life stages are also described with the developmental progress of molecular assays to provide sensitive resistancedetection tests. Overall, this paper provides valuable perception into the current understanding of AR in Haemonchus spp. and the challenges faced in the management of this disease in Asia. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
28. Assessment of the Spatiotemporal Impact of Water Conservation on the Qinghai–Tibet Plateau.
- Author
-
Wen, Xin, Shao, Huaiyong, Wang, Ying, Lv, Lingfeng, Xian, Wei, Shao, Qiufang, Shu, Yang, Yin, Ziqiang, Liu, Shuhan, and Qi, Jiaguo
- Subjects
- *
WATER conservation , *WATER management , *ECOLOGICAL zones , *WATER supply , *REMOTE sensing - Abstract
The Qinghai–Tibet Plateau is a proven essential water conservation region in Asia. However, various factors, such as anthropogenic activities, climate, and vegetation significantly affect its water conservation. Along these lines, a deep understanding of the spatiotemporal patterns of water conservation for this plateau and relevant influencing elements is considered of great importance. This paper calculates the water conservation on the Qinghai–Tibet Plateau based on the InVEST model, and given that the evapotranspiration data are an important parameter of the InVEST model, this study selects the mainstream evapotranspiration data to compare the accuracy of the simulated water yield, and also selects the most accurate remote sensing evapotranspiration data examined in the study to carry out the study of water conservation on the Qinghai–Tibet Plateau. Due to the large area of the Qinghai–Tibet Plateau and the various types of climate and ecological zones, this paper analyzes the spatial and temporal variations of water conservation on the Qinghai–Tibet Plateau in each ecological zone and climate zone division and detects the factors affecting water conservation on the Qinghai–Tibet Plateau by using the geo-detector method. From our analysis, the following outcomes are proven: on the Qinghai–Tibet Plateau, (1) the overall water conservation decreased from southeast to northwest; (2) the water conservation of the studied plateau in 1990, 2000, 2010, and 2020 was 656.56, 590.85, 597.4, and 651.85 mm, respectively; (3) precipitation, evapotranspiration, and NDVI exhibited a positive relationship with water conservation; (4) the precipitation factor had the biggest impact on the spatial distinctions of the water resource governance; (5) the above factors are combined with the slope factor and the interaction of each factor to improve water conservation. Our work provides valuable insights for the further implementation of ecological projects with a view to enhancing water resource management methods. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
29. Diagnostic Performance of Positron Emission Tomography with Fibroblast-Activating Protein Inhibitors in Gastric Cancer: A Systematic Review and Meta-Analysis.
- Author
-
Rizzo, Alessio, Racca, Manuela, Garrou, Federico, Fenocchio, Elisabetta, Pellegrino, Luca, Albano, Domenico, Dondi, Francesco, Bertagna, Francesco, Annunziata, Salvatore, and Treglia, Giorgio
- Subjects
- *
STOMACH cancer , *POSITRON emission tomography , *LYMPHATIC metastasis , *DISEASE relapse , *PROGRESSION-free survival , *METASTASIS - Abstract
Various papers have introduced the use of positron emission tomography (PET) with [68Ga]Ga-radiolabeled fibroblast-activation protein inhibitor (FAPi) radiopharmaceuticals in different subtypes of gastric cancer (GC). Our aim was to assess the diagnostic performance of this novel molecular imaging technique in GC with a systematic review and meta-analysis. A straightforward literature search of papers concerning the diagnostic performance of FAP-targeted PET imaging was performed. Original articles evaluating this novel molecular imaging examination in both newly diagnosed GC patients and GC patients with disease relapse were included. The systematic review included nine original studies, and eight of them were also eligible for meta-analysis. The quantitative synthesis provided pooled detection rates of 95% and 97% for the assessment of primary tumor and distant metastases, respectively, and a pooled sensitivity and specificity of 74% and 89%, respectively, for regional lymph node metastases. Significant statistical heterogeneity among the included studies was found only in the analysis of the primary tumor detection rate (I2 = 64%). Conclusions: Beyond the limitations of this systematic review and meta-analysis (i.e., all the included studies were conducted in Asia, and using [18F]FDG PET/CT as a comparator of the index test), the quantitative data provided demonstrate the promising diagnostic performance of FAP-targeted PET imaging in GC. Nevertheless, more prospective multicentric studies are needed to confirm the excellent performances of FAP-targeted PET in this cluster of patients. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
30. Thinking with Civets: The Role of Zoos in the Decolonisation of Animal Tourism.
- Author
-
Hooper, Jes
- Subjects
- *
ZOO animals , *TOURISM , *ANIMAL welfare , *COFFEE manufacturing , *DECOLONIZATION - Abstract
Simple Summary: The conditions afforded to zoo animals across the globe remain diverse and disparate. This paper brings two forms of animal commodification into dialogue: (1) the management of civets in global zoos and (2) the rising trend in civet coffee production and tourism in Asia. By qualitatively analysing the entanglements between colonialism, animal welfare, and conservation in civet tourism, this paper calls for enhanced reflexivity and decolonisation of animal-based tourism. Suggestions are made on how zoos may answer this call. Civets belong to the family Viverridae, an ancient line of 'cat-like' animals. Despite their large geographic distribution across southeast Asia and parts of Africa, little scientific attention has been attributed to Viverrids or Viverrid–human relations. This paper applies the lens of civets to explore the tensive intersection between animal welfare, conservation, and colonialism within the tourism landscape. Through thinking with civets, this paper brings two forms of animal commodification into dialogue: (1) the management of civets in zoos around the globe and (2) the rising trend in civet coffee production and tourism in Asia. By qualitatively analysing the entanglements between colonialism, animal welfare, and conservation and how each impacts the lives and treatment of civets in tourism, this paper calls for enhanced reflexivity and thus the decolonisation of animal-based tourism. Suggestions are made on how zoos may progress towards the decolonisation of animal tourism, and the argument is made that zoos are well positioned and morally obligated to answer this call. By doing so, greater attention can be given to the animals whose lives are most affected by the global tourism landscape. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
31. Effects of Paper Mulberry Silage on the Milk Production, Apparent Digestibility, Antioxidant Capacity, and Fecal Bacteria Composition in Holstein Dairy Cows.
- Author
-
Hao, Yangyi, Huang, Shuai, Si, Jingfang, Zhang, Jun, Gaowa, Naren, Sun, Xiaoge, Lv, Jiaying, Liu, Gaokun, He, Yaqin, Wang, Wei, Wang, Yajing, and Li, Shengli
- Subjects
- *
SILAGE , *DAIRY cattle , *OXIDANT status , *MILK yield , *MULBERRY , *SUPEROXIDE dismutase - Abstract
Simple Summary: Paper mulberry (Broussonetia papyrifera; PM) is a type of roughage rich in bioactive substances, such as phenolics and flavonoids, which are beneficial for animal health. This study evaluated the apparent digestibility of PM silage in Holstein dairy cows and its effect on the milk production, antioxidant capacity, and fecal bacteria composition of the animals. The results showed that the PM silage had no significant influence on the milk yield, apparent digestibility, and fecal bacteria composition of dairy cows. However, diets with PM silage can enhance the antioxidant and immune capacity of dairy cows, mainly due to the bioactive substance in PM. Today, faced with a shortage of feedstuff resources in ruminants, PM can be a useful feed resource for ruminants. Simultaneously, with the ban on antibiotics, PM may become an important functional feed for protecting animal health. Paper mulberry (Broussonetia papyrifera; PM) is an excellent and extensive type of roughage in Asia. This study aimed to evaluate the effects of PM silage on the milk production, apparent digestibility, antioxidant capacity, and fecal bacteria composition in Holstein dairy cows. Forty-five lactating Holstein dairy cows with a similar milk yield and parity were selected and randomly assigned to three groups. The control group was fed a non-PM silage diet, and the PM-treated groups were fed 4.5 and 9.0% PM silage supplementary diets for 28 days. Then, treatment groups were fed diets containing 13.5 and 18.0% PM silage for the next 28 days, respectively. PM silage increased the milk urea nitrogen and decreased the somatic cell count (p < 0.05), but did not affect the dry matter intake, milk yield, apparent digestibility, and energy balance of dairy cows. PM silage can enhance the blood total antioxidant capacity, superoxide dismutase, and immune globulin content (p < 0.05). The PM silage significantly decreased the relative abundance of the genera Ruminococcaceae UCG-013 and Tyzzerella-4 (p < 0.05). In conclusion, PM silage enhanced the antioxidant capacity and immunity of dairy cows, but did not influence the milk yield, dry matter digestibility, and fecal bacteria composition. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
32. A New Determining Method for Ionospheric F2-Region Peak Electron Density Height.
- Author
-
Wang, Jian, Yu, Qiao, Shi, Yafei, Yang, Cheng, Ji, Shengyun, and Zheng, Yu
- Subjects
- *
ELECTRON density , *MACHINE theory , *MACHINE learning , *WIRELESS communications , *IONOSPHERE , *GEOMAGNETISM , *ELECTRODYNAMICS - Abstract
The height of the F2 peak electron density (hmF2) is an essential parameter in studying ionospheric electrodynamics and high-frequency wireless communication. Based on ionosphere ray propagation theory, the physical relationship between M3000F2 and hmF2 is derived and visualized. Furthermore, based on the above physical theory and the machine learning method, this paper proposes a new model for determining hmF2 using propagation factor at a distance of 3000 km from the ionospheric F2 layer, time, and season. This proposed model is easy to understand and has the characteristics of clear principles, simple structure, and easy application. Furthermore, we used six stations in east Asia to verify this model and compare it with the other three models of the International Reference Ionosphere (IRI) model. The results show that the proposed model (PRO) has minor error and higher accuracy. Specifically the RMSE of the BSE, AMTB, SHU, and the PRO models were 20.35 km, 31.51 km, 13.59 km, and 5.68 km, respectively, and the RRMSE of the BSE, AMTB, SHU, and PRO models were 8.17%, 11.88%, 4.96%, and 2.12%, respectively. In addition, the experimental results show that the PRO model can better predict the trend of the hmF2 inflection point. This method can be further extended to add data sources and provide new ideas for studying the hmF2 over global regions. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
33. Weighted Signed Networks Reveal Interactions between US Foreign Exchange Rates.
- Author
-
Yang, Leixin, Wang, Haiying, Gu, Changgui, and Yang, Huijie
- Subjects
- *
FOREIGN exchange rates , *FOREIGN exchange market , *INTERNATIONAL trade , *MULTICASTING (Computer networks) - Abstract
Correlations between exchange rates are valuable for illuminating the dynamics of international trade and the financial dynamics of countries. This paper explores the changing interactions of the US foreign exchange market based on detrended cross-correlation analysis. First, we propose an objective way to choose a time scale parameter appropriate for comparing different samples by maximizing the summed magnitude of all DCCA coefficients. We then build weighted signed networks under this optimized time scale, which can clearly display the complex relationships between different exchange rates. Our study shows negative cross-correlations have become pyramidally rare in the past three decades. Both the number and strength of positive cross-correlations have grown, paralleling the increase in global interconnectivity. The balanced strong triads are identified subsequently after the network centrality analysis. Generally, while the strong development links revealed by foreign exchange have begun to spread to Asia since 2010, Europe is still the center of world finance, with the euro and Danish krone consistently maintaining the closest balanced development relationship. Finally, we propose a fluctuation propagation algorithm to investigate the propagation pattern of fluctuations in the inferred exchange rate networks. The results show that, over time, fluctuation propagation patterns have become simpler and more predictable. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
34. Global Neuropsychopharmacological Prescription Trends in Adults with Schizophrenia, Clinical Correlates and Implications for Practice: A Scoping Review.
- Author
-
Ying, Jiangbo, Chew, Qian Hui, Wang, Yuxi, and Sim, Kang
- Subjects
- *
PEOPLE with schizophrenia , *PSYCHIATRIC drugs , *MEDICAL prescriptions , *MOOD stabilizers , *ANTIPSYCHOTIC agents , *NEUROLEPTIC malignant syndrome - Abstract
It is important to examine the psychotropic prescription practices in schizophrenia, as it can inform regarding changing treatment choices and related patient profiles. No recent reviews have evaluated the global neuropsychopharmacological prescription patterns in adults with schizophrenia. A systematic search of the literature published from 2002 to 2023 found 88 empirical papers pertinent to the utilization of psychotropic agents. Globally, there were wide inter-country and inter-regional variations in the prescription of psychotropic agents. Overall, over time there was an absolute increase in the prescription rate of second-generation antipsychotics (up to 50%), mood stabilizers (up to 15%), and antidepressants (up to 17%), with an observed absolute decrease in the rate of antipsychotic polypharmacy (up to 15%), use of high dose antipsychotic (up to 12% in Asia), clozapine (up to 9%) and antipsychotic long-acting injectables (up to 10%). Prescription patterns were mainly associated with specific socio-demographic (such as age), illness (such as illness duration), and treatment factors (such as adherence). Further work, including more evidence in adjunctive neuropsychopharmacological treatments, pharmaco-economic considerations, and examination of cohorts in prospective studies, can proffer insights into changing prescription trends relevant to different treatment settings and predictors of such trends for enhancement of clinical management in schizophrenia. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
35. Microbiota Ecosystem Services in Vineyards and Wine: A Review.
- Author
-
García-Izquierdo, Isabel, Colino-Rabanal, Victor J., Tamame, Mercedes, and Rodríguez-López, Fernando
- Subjects
- *
ECOSYSTEM services , *WINE service , *AGRICULTURE , *BIOLOGICAL pest control , *NUCLEOTIDE sequencing - Abstract
The domestication of vines started in Asia 11,000 years ago, although it was not until the 19th century that oenology was established as a scientific discipline thanks to the research of Louis Pasteur on the role of microorganisms in wine fermentation. At the present time, the progression in next-generation sequencing (NGS) technologies is helping to facilitate the identification of microbial dynamics during winemaking. These advancements have aided winemakers in gaining a more comprehensive understanding of the role of microbiota in the fermentation process, which, in turn, is ultimately responsible for the delivery of provisioning (wine features and its production), regulating (such as carbon storage by vineyards, regulation of soil quality, and biocontrol of pests and diseases) or cultural (such as aesthetic values of vineyard landscapes, scholarly enjoyment of wine, and a sense of belonging in wine-growing regions) ecosystem services. To our knowledge, this is the first review of the state of knowledge on the role of microbiota in the delivery of ecosystem services in the wine sector, as well as the possibility of valuing them in monetary terms by operating logic chains, such as those suggested by the SEEA-EA framework. This paper concludes with a review of management practices that may enhance the value of microbiota ecosystem services and the role of smart farming in this task. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
36. Strength Prediction of Non-Sintered Hwangto-Substituted Concrete Using the Ultrasonic Velocity Method.
- Author
-
Im, Hajun, Kim, Wonchang, Choi, Hyeonggil, and Lee, Taegyu
- Subjects
- *
ULTRASONIC testing , *CONCRETE , *POROSITY , *SCANNING electron microscopy , *ULTRASONICS , *CONSTRUCTION materials , *COMPRESSIVE strength - Abstract
This paper presents and investigates the properties of concrete in which a portion of the cement is substituted with non-sintered Hwangto (NSH), a readily available building material in Asia. Given the inactive nature of NSH, this study aimed to determine the optimal cement replacement ratio and quantitative strength of the material. The unit weight, compressive strength, ultrasonic pulse velocity (UPV), and stress–strain of the NSH concrete (NSHC) were evaluated. Additionally, we developed a predictive model for determining compressive strength based on the regression analysis of compressive strength and UPV. The water-to-binder ratio was set to 0.41, 0.33, and 0.28, and the NSH replacement rates in the cement were set to 0%, 15%, 30%, and 45% for evaluating various strength ranges. The mechanical property measurements indicated reductions of 5.35% in unit weight, 35.62% in compressive strength, and 6.34% in UPV as the NSH was replaced. Notably, the smallest deviation from plain concrete was observed at a replacement rate of 15%. The scanning electron microscopy analysis results showed that the plain concrete exhibited a crystalloid structure; however, as the NSH replacement rate increased, the amorphous structure and pores increased while unreacted NSH particles were also observed. The X-ray diffraction analysis results demonstrate that the peak intensities for kaolinite and mullite increased as the NSH replacement rate increased, while those of C–S–H gel and CaO showed low peak intensities. Furthermore, the regression analysis concluded that an exponential function was suitable. Consequently, a compressive strength prediction model was developed, and in the error test, the NSHC model demonstrated an average error of <10%, with fewer errors at the lower compressive strength boundaries. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
37. Biological control of fall armyworm Spodoptera frugiperda (JE Smith) using egg parasitoids, Trichogramma species (Hymenoptera: Trichogrammatidae): a review.
- Author
-
Navik, Omprakash, Yele, Yogesh, Kedar, Santosh C., and Sushil, S. N.
- Subjects
- *
FALL armyworm , *TRICHOGRAMMA , *TRICHOGRAMMATIDAE , *HYMENOPTERA , *BIOLOGICAL control of insects , *SUSTAINABILITY - Abstract
Background: Fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is an invasive pest that can cause serious crop loss to various important food crops and risk to global food security. FAW can cause damage to over 350 plant species by feeding on vegetative and reproductive stages of crops. Currently, chemical pesticides and transgenic maize are widely used to safeguard crops from this serious pest. However, biological control is a safer and more sustainable alternative in the long term for FAW management. Of the various natural enemies of FAW, egg parasitoids of genus Trichogramma have been used in augmentative biological control of FAW in the Americas and invaded regions such as Africa and Asia. Main body: Several species of Trichogramma have been reported naturally parasitizing FAW eggs and emerged as important biocontrol agents. This paper presents a comprehensive review of potential and challenges associated with Trichogramma in biological control of FAW. A total of 11 species of trichogrammatids occurred naturally on FAW eggs. This review includes the occurrence of Trichogramma species on FAW, biological attributes, mass rearing, release techniques, field efficacy and interaction and integration with other parasitoids. Integration of Trichogramma with other parasitoids can resolve the problem related to its penetrative ability against scaled and multi-layered FAW eggs which were discussed. Conclusion: Invasion of FAW in Africa and Asia has provided a prospect for augmentative biological control of FAW using Trichogramma for sustainable production, especially in maize which is used as food and fodder. Integrating Trichogramma with safer and selective green pesticides and their conservation with other natural enemies could help in sustainable and environment-friendly FAW control. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
38. Measuring health equity in the ASEAN region: conceptual framework and assessment of data availability.
- Author
-
Barcellona, Capucine, Mariñas, Bryanna Yzabel, Tan, Si Ying, Lee, Gabriel, Ko, Khin Chaw, Chham, Savina, Chhorvann, Chhea, Leerapan, Borwornsom, Pham Tien, Nam, and Lim, Jeremy
- Subjects
- *
EVALUATION of medical care , *KEY performance indicators (Management) , *HEALTH services accessibility , *WORLD health , *HEALTH outcome assessment , *CONCEPTUAL structures , *DOCUMENTATION , *DATABASE management , *BENCHMARKING (Management) , *CLINICAL medicine , *GOVERNMENT policy , *RESEARCH funding , *FINANCIAL management , *POPULATION health , *INSURANCE - Abstract
Background: Existing research on health equity falls short of identifying a comprehensive set of indicators for measurement across health systems. Health systems in the ASEAN region, in particular, lack a standardised framework to assess health equity. This paper proposes a comprehensive framework to measure health equity in the ASEAN region and highlights current gaps in data availability according to its indicator components. Methods: A comprehensive literature review was undertaken to map out a core set of indicators to evaluate health equity at the health system level. Secondary data collection was subsequently conducted to assess current data availability for ASEAN states in key global health databases, national health accounts, and policy documents. Results: A robust framework to measure health equity was developed comprising 195 indicators across Health System Inputs and Processes, Outputs, Outcomes, and Contextual Factors. Total indicator data availability equated to 72.9% (1423/1950). Across the ASEAN region, the Inputs and Processes sub-component of Health Financing had complete data availability for all indicators (160/160, 100%), while Access to Essential Medicine had the least data available (6/30, 20%). Under Outputs and Outcomes, Coverage of Selected Interventions (161/270, 59.63%) and Population Health (350/350, 100%) respectively had the most data available, while other indicator sub-components had little to none (≤ 38%). 72.145% (384/530) of data is available for all Contextual Factors. Out of the 10 ASEAN countries, the Philippines had the highest data availability overall at 77.44% (151/195), while Brunei Darussalam and Vietnam had the lowest data availability at 67.18% (131/195). Conclusions: The data availability gaps highlighted in this study underscore the need for a standardised framework to guide data collection and benchmarking of health equity in ASEAN. There is a need to prioritise regular data collection for overlooked indicator areas and in countries with low levels of data availability. The application of this indicator framework and resulting data availability analysis could be conducted beyond ASEAN to enable cross-regional benchmarking of health equity. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
39. Prevalence of road traffic injuries in South East and South Asian region - A systematic review.
- Author
-
Vinish, V., Chakrabarty, Jyothi, Vijayan, Sandeep, Nayak, Baby S., Shashidhara, Y. N., Kulkarni, Mahesh, and Noronha, Judith A.
- Subjects
- *
TRAFFIC accidents , *AGE groups , *CITIES & towns , *WOUNDS & injuries , *YOUNG adults - Abstract
Background: South and South-East Asian countries report a great liability for the world's road traffic injuries (RTIs) and deaths. A vast number of research studies tested various interventions including specific protective devices to prevent accidents, but no review papers have been conducted to find out the prevalence of RTIs in South-East and South Asian countries. Objective: This review paper was an attempt to find out the prevalence of RTIs and their associated factors in South-East and South Asian countries. Methods: Following the guidelines of Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA), we searched the articles in the electronic databases of PubMed/Medline, Scopus, CINAHL, ProQuest, and Web of Science. Articles were selected if they reported the prevalence of RTI, or road traffic accident (RTA) deaths. In addition, a data quality assessment was done. Results: Out of the 10,818 article hits from the literature search, ten articles found the eligibility and inclusion criteria. Most of the studies reported that males are involved in the RTIs more than females. The male mortality rate is more than the female mortality in RTI mortality. Young adult males are the major victims when compared with the different age groups of male victims. Two-wheelers are the major contributors to the accident rate. Religious or national festivals are not free from accident-prone times. Climatic seasons and nighttime have a major influence on the RTIs. RTIs are increasing due to the sudden and huge increase in the number of motor vehicles and the development of cities and towns. Conclusion: Accidents are non-predictable but controllable disasters in society. Overspeeding, bad conditions on road, the vulnerability of the vehicles, and careless driving are the major reported reasons for RTIs. Making and implementing strict laws can help us to control RTAs. The major effect on the reduction of RTI can be assured only with the presence of responsible people. That can be achieved only by creating awareness in society about traffic rules and responsibilities. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
40. The mean reversion/persistence of financial cycles: Empirical evidence for 24 countries worldwide.
- Author
-
Shengnan Lv, Zeshui Xu, Xuecheng Fan, Yong Qin, and Skare, Marinko
- Subjects
- *
GLOBAL Financial Crisis, 2008-2009 , *FINANCIAL crises , *BUSINESS cycles , *FINANCIAL markets - Abstract
Research background: The globalization trend has inevitably enhanced the connectivity of global financial markets, making the cyclicality of financial activities and the spread of market imbalances have received widespread attention, especially after the global financial crisis. Purpose of the article: To reduce the negative effects of the contagiousness of the financial cycles, it is necessary to study the persistence of financial cycles and carve out the total connectedness, spillover paths, and sources of risks on a global scale. In addition, understanding the relationship between the financial cycle and economic development is an important way to prevent financial crises. Methods: This paper adopts the nonlinear smoothing transition autoregressive (STAR) model to extract cyclical and phase characteristics of financial cycles based on 24 countries during 1971Q1-2015Q4, covering developed and developing countries, the Americas, Europe, and Asia regions. In addition, the frequency connectedness approach is used to measure the connectedness of financial cycles and the relationship between the global financial cycle and the global economy. Findings & value added: The analysis reveals that aggregate financial cycles persist for 13.3 years for smoothed and 8.7 years for unsmoothed on average. The national financial cycles are asynchronous and exhibit more prolonged expansions and faster contractions. The connectedness of financial cycles is highly correlated with systemic crises and contributes to the persistence and harmfulness of shocks. It is mainly driven by short-term components and exhibits more pronounced interconnectedness within regions than across regions. During the financial crisis, the global financial cycle movements precede and are longer than the business fluctuations. Based on the study, some policy implications are presented. This paper emphasizes the impact of systemic crises on the persistence of financial cycles and their connectedness, which contributes to refining research related to the coping mechanisms of financial crises. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
41. Chapters on Asia: Selected Papers from the Lee Kong Chian Research Fellowship (2021).
- Subjects
- *
SCHOLARSHIPS , *NATIONAL archives , *NATIONAL libraries , *ELECTRONIC books , *SOUND recording industry - Published
- 2023
42. Decreasing Species Richness with Increase in Elevation and Positive Rapoport Effects of Crambidae (Lepidoptera) on Mount Taibai.
- Author
-
Chen, Anping, Li, Zhijie, Zheng, Yufeng, Zhan, Jinyu, Yang, Bolan, and Yang, Zhaofu
- Subjects
- *
CRAMBIDAE , *SPECIES diversity , *LEPIDOPTERA , *MORPHOLOGY , *GENETIC barcoding - Abstract
Simple Summary: Based on the investigation of altitudinal distribution data with identification by using both molecular and morphological classifications of Pyraustinae and Spilomelinae, this paper determines the altitudinal gradient pattern for these two subfamilies on the north slope of Mount Taibai of the Qinling Mountains, and provides a test of the universality of Rapoport's rule in Lepidoptera by using four methods. Our results show that alpha diversity of Pyraustinae and Spilomelinae both decrease with rising altitude. By contrast, the species distribution ranges increase with rising altitude. Three of the four methods used to test Rapoport's rule yielded positive results, while Rohde's results show a unimodal distribution model and do not support Rapoport's rule. Rapoport's rule proposes that a species' range size increases with the increase in a gradient (such as latitude, altitude or water depth). However, altitudinal distributions and Rapoport's rule have rarely been tested for Asian Lepidoptera. Pyraustinae and Spilomelinae (Lepidoptera: Crambidae) are extremely diverse in temperate Asia, including on Mount Taibai, which is considered a hotspot area for studying the vertical distribution patterns of insect species. Based on the investigation of altitudinal distribution data with identification by using both DNA barcoding and the morphological classification of Pyraustinae and Spilomelinae, this paper determines the altitudinal gradient pattern for these two subfamilies on the north slope of Mount Taibai, and provides a test of the universality of Rapoport's rule in Lepidoptera by using four methods, including Stevens' method, Pagel's method, Rohde's method, and the cross-species method. Our results show that the alpha diversity of Pyraustinae and Spilomelinae both decrease with rising altitude. By contrast, the species' ranges increase with rising altitude. Three of the four methods used to test Rapoport's rule yielded positive results, while Rohde's results show a unimodal distribution model and do not support Rapoport's rule. Our findings fill the research gap on the elevational diversity of Lepidoptera in temperate Asia. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
43. Study on the dynamic distribution of spores of powdery mildew pathogen in wheat by rotor airflow of plant protection UAV.
- Author
-
Qin, Weicai, Chen, Panyang, and He, Ruyan
- Subjects
- *
PLANT protection , *SPORES , *POWDERY mildew diseases , *AIR flow , *INSECTICIDE application , *AGRICULTURE - Abstract
Plant protection drones are fast and efficient application machines that are characterised by high application efficiency and no damage to crops. They are particularly suitable for small areas of farmland and mountainous terrain in regions such as Asia and are currently the dominant insecticide application technology in China. The presence of wind is a prerequisite for the spread and dissemination of airborne diseases and it can directly influence the distance and height of ascent of pathogenic spores. This paper investigates the effect of downwash airflow generated by the flight altitude of a plant protection drone on the horizontal distribution, vertical distribution and ground distribution of powdery mildew spores in wheat. Monitoring the changing dynamics of airborne powdery mildew conidia using spore traps. The test results show that: the number of powdery mildew pathogenic spores is related to various factors such as weather, relative humidity and wind speed; the release of spores is greatly influenced by airflow disturbances but has little effect at the early stages of sporulation; the disease is caused by the accumulation process of pathogenic spores and in the control of powdery mildew in wheat, preventive spraying should be carried out within 2–3 days of the germination of pathogenic spores. The study lays the foundation for further in-depth research on the spread of powdery mildew spores and improved pest control, and provides a basis for scientific and rational spraying and control by agricultural drones. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
44. Time series forecasting of COVID-19 infections and deaths in Alpha and Delta variants using LSTM networks.
- Author
-
Sheikhi, Farnaz and Kowsari, Zahra
- Subjects
- *
SARS-CoV-2 Delta variant , *COVID-19 , *TIME series analysis , *STANDARD deviations , *COVID-19 pandemic , *DEEP learning - Abstract
Since the beginning of the rapidly spreading COVID-19 pandemic, several mutations have occurred in the genetic sequence of the virus, resulting in emerging different variants of concern. These variants vary in transmissibility, severity of infections, and mortality rate. Designing models that are capable of predicting the future behavior of these variants in the societies can help decision makers and the healthcare system to design efficient health policies, and to be prepared with the sufficient medical devices and an adequate number of personnel to fight against this virus and the similar ones. Among variants of COVID-19, Alpha and Delta variants differ noticeably in the virus structures. In this paper, we study these variants in the geographical regions with different size, population densities, and social life styles. These regions include the country of Iran, the continent of Asia, and the whole world. We propose four deep learning models based on Long Short-Term Memory (LSTM), and examine their predictive power in forecasting the number of infections and deaths for the next three, next five, and next seven days in each variant. These models include Encoder Decoder LSTM (ED-LSTM), Bidirectional LSTM (Bi-LSTM), Convolutional LSTM (Conv-LSTM), and Gated Recurrent Unit (GRU). Performance of these models in predictions are evaluated using the root mean square error, mean absolute error, and mean absolute percentage error. Then, the Friedman test is applied to find the leading model for predictions in all conditions. The results show that ED-LSTM is generally the leading model for predicting the number of infections and deaths for both variants of Alpha and Delta, with the ability to forecast long time intervals ahead. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
45. A hydraulic model of the Amur River informed by ICESat-2 elevation.
- Author
-
Bauer-Gottwein, Peter, Zakharova, Elena, Coppo Frías, Monica, Ranndal, Heidi, Nielsen, Karina, Christoffersen, Linda, Liu, Jun, and Jiang, Liguang
- Subjects
- *
HYDRAULIC models , *FLOOD risk , *ALTITUDES , *DROUGHT management , *DROUGHT forecasting , *SPATIAL resolution - Abstract
Accurate predictions of water surface elevation (WSE) in rivers at high spatial and temporal resolution are important for flood/drought risk assessment and flood/drought forecasting and management. WSE in a river is controlled by three main factors: discharge, riverbed geometry, and hydraulic roughness. In remote and poorly instrumented rivers, discharge and riverbed geometry are highly uncertain and WSE is therefore hard to predict. ICESat-2 laser altimetry provides accurate elevation transects across the river at very high spatial resolution (70 cm along track). This paper demonstrates how ICESat-2 elevation transects can be used to parameterize a basin-scale hydraulic model of a continental-scale river. The workflow is demonstrated for the transboundary Amur River in North-East Asia. Simulated WSE is subsequently validated against a large dataset of in situ and satellite altimetry observations, and we demonstrate that the model can reproduce available WSE observations throughout the basin with an accuracy of 1–2 m. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
46. GIS-Based Multi-Criteria Evaluation (MCE) Methods for Aquaculture Site Selection: A Systematic Review and Meta-Analysis.
- Author
-
Chentouf, Sanae, Sebbah, Boutaina, Bahousse, El Houssine, Wahbi, Miriam, and Maâtouk, Mustapha
- Subjects
- *
GEOGRAPHIC information systems , *FISH farming , *AQUACULTURE , *SOIL quality , *WATER quality , *SOCIOECONOMIC factors - Abstract
With the growing demand for aquatic products, aquaculture has become a prominent means of meeting this demand. However, the selection of suitable sites for aquaculture remains a key factor in the success of any aquaculture operation. While various methods exist for site selection, geographic information system (GIS)-based multi-criteria evaluation (MCE) methods have emerged as the most widely utilized approach to identifying potential aquaculture sites. Following the guidelines of the preferred reporting items for systematic reviews and meta-analyses (PRISMA), this paper presents a systematic review and meta-analysis of GIS-based MCE methods used in aquaculture sites selection. The objective of this study is to offer a comprehensive overview of existing research in this field and develop a general model for selecting sites for fish and shellfish aquaculture. The main findings indicate a growing number of studies utilizing GIS-based MCE in aquaculture site selection in recent years, with Asia being the leading continent in terms of publications in this domain. Among the journals publishing in this field, the Aquaculture journal stands out as the top publisher. Using consistent criteria across the reviewed studies, two models have been generated, each consisting of four sub-models: water quality, soil quality, infrastructure, and socioeconomic factors; and topography, environment, and physical parameters. These models can aid future researchers and assist decision-makers in identifying optimal locations for aquaculture development. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
47. Intravitreal DEX Implant for the Treatment of Diabetic Macular Edema: A Review of National Consensus.
- Author
-
Spinetta, Roberta, Petrillo, Francesco, Reibaldi, Michele, Tortori, Antonia, Mazzoni, Maria, Metrangolo, Cristian, Gelormini, Francesco, Ricardi, Federico, and Giordano, Antonio
- Subjects
- *
MACULAR edema , *INTRAOCULAR lenses , *LASER photocoagulation , *CATARACT surgery , *PREGNANT women , *RETINA - Abstract
Diabetic macular edema (DME)'s therapeutic approach can frequently be challenging. The purpose of the review is to propose evidence-based recommendations on the employment of intravitreal dexamethasone implants (DEX) when approaching patients suffering from DME. Seven national consensuses redacted by different groups of retina specialists from Europe and Asia were examined and confronted. Each consensus was redacted utilizing a Delphi approach, in person meetings, or by reviewing the literature. DEX can be studied as a first-line strategy in individuals suffering from DME with inflammatory OCT biomarkers, in vitrectomized eyes, in patients with recent cardiovascular events, in pregnant women, in patients scheduled to undergo cataract surgery or with poor compliance. The other parameters considered were the indications to the DME treatment, when to switch to DEX, the definition of non-responder to anti-VEGFs agents and to the DEX implant, whether to combine DEX with laser photocoagulation, the association between glaucoma and DEX, and the management of DEX and the cataract. Although several years have passed since the introduction of DEX implants in the DME treatment, there is still not a unified agreement among retina specialists. This paper compares the approach in the DME treatment between countries from different continents and provides a broader and worldwide perspective of the topic. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
48. Bioethics in Northeast Asia.
- Author
-
Laurie, Graeme T.
- Subjects
- *
BIOETHICS , *ATTITUDES toward technology , *PUBLIC opinion , *MORAL development - Abstract
As the authors suggest, the Japanese experience can serve as an illustrative lesson for other countries faced with similar technological developments and governance challenges, including the politics of bioethics that are inevitable in contemporary biomedicine. Before turning to the papers that make up this issue, it is important to give our readers an update on the commitment of the Asian Bioethics Review to matters of equity, diversity and inclusion (EDI). This October 2023 issue of Asian Bioethics Review showcases work with a focus on Northeast Asia. [Extracted from the article]
- Published
- 2023
- Full Text
- View/download PDF
49. Gulls as a host for both gamma and deltacoronaviruses.
- Author
-
Domańska-Blicharz, Katarzyna, Miłek-Krupa, Justyna, and Pikuła, Anna
- Subjects
- *
CORONAVIRUSES , *GULLS , *WHOLE genome sequencing , *PIGEONS , *CHARADRIIFORMES , *VITRONECTIN , *SEQUENCE analysis - Abstract
The coronaviruses (CoV) are ubiquitous pathogens found in wide variety of hosts that constantly pose a threat to human and animal health as a result of their enormous capacity to generate genetic changes. Constant monitoring of virus reservoirs can constitute an early-warning tool and control the spread and evolution of the virus. Coronaviruses are common in wild birds, globally, and birds of the Charadriiformes in particular have been demonstrated to be carriers of delta- (dCoV) and gammacoronaviruses (gCoV). In this paper, we present the genetic characterisation of five CoV strains from black-headed (Chroicocephalus ridibundus) and common (Larus canus) gulls. Whole genome sequence analysis showed high similarity of detected dCoV in gulls to previously identified strains from falcon, houbara, pigeon and gulls from Asia (UAE, China). However, phylogenetic analysis revealed bifurcation within a common branch. Furthermore, the accumulation of numerous amino acid changes within the S-protein was demonstrated, indicating further evolution of dCoV within a single gull host. In turn, phylogenetic analysis for the most of the structural and non-structural genes of identified gCoV confirmed that the strain belongs to the duck coronavirus 2714 (DuCoV2714) species within Igacovirus subgenera, while for the spike protein it forms a separate branch not closely related to any gCoV species known to date. The current study provides new and significant insights into the evolution and diversification of circulating coronaviruses in members of Laridae family. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
50. Mathematical Modeling and Stability Analysis of the Delayed Pine Wilt Disease Model Related to Prevention and Control.
- Author
-
Dong, Ruilin, Sui, Haokun, and Ding, Yuting
- Subjects
- *
CONIFER wilt , *MEDICAL model , *MULTIPLE scale method , *TIME delay systems , *DELAY differential equations - Abstract
Forest pests and diseases have been seriously threatening ecological security. Effective prevention and control of such threats can extend the growth cycle of forest trees and increase the amount of forest carbon sink, which makes a contribution to achieving China's goal of "emission peak and carbon neutrality". In this paper, based on the insect-vector populations (this refers to Monochamus alternatus, which is the main vector in Asia) in pine wilt disease, we establish a two-dimensional delay differential equation model to investigate disease control and the impact of time delay on the effectiveness of it. Then, we analyze the existence and stability of the equilibrium of the system and the existence of Hopf bifurcation, derive the normal form of Hopf bifurcation by using a multiple time scales method, and conduct numerical simulations with realistic parameters to verify the correctness of the theoretical analysis. Eventually, according to theoretical analysis and numerical simulations, some specific suggestions are put forward for prevention and control of pine wilt disease. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.