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Abstract: In this paper, a novel algorithm is proposed for solving multiobjective optimization problems. The proposed algorithm, multiobjective differential evolution (MODE), is applied to optimize industrial adiabatic styrene reactor considering productivity, selectivity and yield as the main objectives. Five combinations of the objectives are considered. Pareto set (a set of equally good solutions) obtained for all the cases is compared with results reported using non-dominated sorting genetic algorithm (NSGA). The results show that all objectives besides profit can be improved compared to those reported using NSGA and current operating conditions. The Pareto optimal front provides wide-ranging optimal operating conditions and an appropriate operating point can be selected based on the requirements of the user. [Copyright &y& Elsevier]