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1. Outer Membrane Protein OmpW Is the Receptor for Typing Phage VP5 in the Vibrio cholerae O1 El Tor Biotype.

Author

Donglei Xu, Jingyun Zhang, Jie Liu, Jialiang Xu, Haijian Zhou, Lijuan Zhang, Jun Zhu, and Biao Kan

Subjects
*MEMBRANE proteins, *VIBRIO cholerae, *CELL receptors, *GENETIC mutation, *BACTERIOPHAGE typing, *CAPSIDS
Abstract

Phage typing is used for the subtyping of clones of epidemic bacteria. In this study, we identified the outer membrane protein OmpW as the receptor for phage VP5, one of the typing phages for the Vibrio cholerae O1 El Tor biotype. A characteristic 11-bp deletion in ompW was observed in all epidemic strains resistant to VP5, suggesting that this mutation event can be used as a tracing marker in cholera surveillance. [ABSTRACT FROM AUTHOR]

Published
2014
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