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Cellular heterogeneous networks (HetNets), which are realized through shared carrier deployments of macrocells and small cells, are widely seen as a potential solution to serve growing data capacity demands. While these networks pose significant challenges in interference management, much of the focus in earlier efforts has been limited only to small-cell range expansion in the downlink. In this paper, we provide a comprehensive analysis of interference management techniques applicable to the uplink of cellular HetNets, with the goal of characterizing and improving edge user (e.g., 5th percentile) performance. In particular, we propose and study virtual soft-handoff (VSHO), which offers a low-complexity and low-overhead solution that exploits the link asymmetry observed in the uplink geometry of HetNets. VSHO exploits the fact that, in the uplink, an edge macro user who suffers from very low throughput may be closer to a nearby small cell than its own macrocell. The intuition is that such macro users should have better decoding opportunity when their signals are processed at the nearby small cell with better channel conditions. We also study how interference cancelation (IC) and interference avoidance through resource blanking can be incorporated into our VSHO proposal for further throughput gains. In addition to the VSHO techniques outlined in this paper, we also analyze other candidate techniques available in the Third Generation Partnership Project Long-Term Evolution (3GPP-LTE), such as cell-range expansion (CRE) and joint processing, to present a unified view of interference management options available in HetNets. [ABSTRACT FROM PUBLISHER]