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This paper first explores spatial distributions and patterns of COVID-19 case rates (cases/100,000 people) and mortality rates (deaths/100,000 people) and their disparities between urban and rural counties in the contiguous US. A county-level social vulnerability index was created using principal component analysis. Social vulnerability components were regressed against both county case and mortality rates. Results suggest that hotspots of case and mortality rates are clustered in Midwest and Upper-Midwest US. We found substantial disparities in case and mortality rates between urban and rural counties. County social vulnerability was positively correlated with both case and mortality rates suggesting counties with higher social vulnerability had higher case and mortality rates. Relationships between social vulnerability components and case and mortality rates vary across the conterminous US. Additionally, counties with increased racial and ethnic minorities, higher percentages of minors, and lower median household income are associated with higher COVID-19 case and mortality rates. [ABSTRACT FROM AUTHOR]

Introduction: The goal of the paper is to characterize the geographic and sociodemographic patterns of policies prohibiting tobacco sales to people aged <21 years (i.e., Tobacco 21) at the local, county, and state levels in the U.S. before the national law.Methods: This study assessed area-level markers for region, race/ethnicity, education, poverty status, and smoke-free law coverage as predictors of Tobacco 21 passage as of December 20, 2019, using modified Poisson and negative binomial regression models with robust SEs. Data were analyzed in 2020.Results: Before the passage of the national policy, 191 million people were covered by Tobacco 21 laws. Counties with higher percentages of non-Hispanic Blacks and individuals living below the poverty line had a lower probability of coverage, whereas counties with higher percentages of Hispanics/Latinxs and individuals with a college degree had a higher probability of coverage. Tobacco 21 coverage also varied by region, with far greater coverage in the Northeast than in the Midwest and South.Conclusions: The national Tobacco 21 law may address disparities in coverage by SES, race/ethnicity, and region that could have lasting implications with regard to health equity. [ABSTRACT FROM AUTHOR]

Introduction: Males are born slightly in excess of females and many factors have been shown to influence M/F, the sex ratio at birth. Seasonality has also been shown to impinge on M/F. This study was carried out in order to ascertain whether Thanksgiving Day, Christmas Day and Valentine's Day had any influence on M/F in the United States population, nine months later.Methods: Births by ethnicity, region and sex were obtained from the website of the Centres for Disease Control. Analyses were applied to seasonally adjusted time series and non-seasonally adjusted series. A seasonally adjusted indirect result was calculated for the sex ratio.Results: This paper studied 53,105,069 live births for 2003-2015 (27,178,968 males, 25,926,101 females). M/F rises exceeding 90th and 95th percentiles were strongest for the seasonally adjusted series for all births in regions: South (CENS-R3), West (CENS-R4) and the time series All-regions_All-race. When comparing unadjusted and seasonally adjusted series, a similar pattern was observed in the regions Northeast and Midwest for American Indian or Alaska Native and Asian or Pacific Islander. A similar pattern was observed for the region Midwest for the ethnic group White.Discussion: M/F rose above the 90th percentile in all the series and occasionally above the 95th percentile. Increased periconceptual coital rates increases M/F and this study thus lends further credence to the hypothesis that coital rates around the time of conception causally influences the sex ratio of subsequent births nine months later, possibly due to a hormonal mechanism. [ABSTRACT FROM AUTHOR]