Search

Ground fissures on the Beijing Plain are highly concealed and displaced, causing significant economic losses and environmental damage. However, there have been few evaluations of the economic losses caused by ground fissures. In this study, the Songzhuang ground fracture (Shuangbutou Village–Dapang Village section) was selected as the research area and combined with the field investigation of ground fracture data in 2016 and 2022, as well as the housing appraisal data in 2018. A direct economic loss evaluation model for ground fracture disasters was established for the first time, and the current and predicted losses were quantitatively evaluated. According to the statistical analysis, the damage caused by ground fractures in this section was mainly to civil buildings, and the number of disaster-affected objects increased by 137.26% during the six years (2016-2022). By the end of 2016, 2018 and 2022, the total value of direct economic losses due to disasters was 46.23 million yuan, 70.33 million yuan and 107.51 million yuan, respectively, with an average annual growth of approximately 10.21 million yuan per year. The total direct economic losses in the region are expected to be approximately 150 million yuan and 410 million yuan by 2025 and 2035, respectively. [ABSTRACT FROM AUTHOR]

How to allocate tasks efficiently and reasonably is one of the key problems in the research of spatial crowdsourcing. This paper proposed a MQTAM to solve the problem of low allocation efficiency of SC, and proposed an improved particle swarm optimization algorithm. The model took into account the time delay of task completion and the reliability of task completion, and used SCTAM_PSO algorithm to search the optimal assignment scheme to improve the task completion quality. The experimental results and analysis show that the MQTAM and SCTAM are effective and feasible. [ABSTRACT FROM AUTHOR]

AIM: To investigate whether Panax notoginseng saponins (PNS) attenuate arecoline (ANE)-induced human oral submucous fibrosis (OSF) by regulating ferroptosis, and to study its mechanism. METHODS: The OSF model was established by treating human immortalized keratinocyte cell line HaCaT with ANE. There were 6 groups created: blank group, model group(50 mg/L ANE), low-, medium- and high-dose (12. 5, 25 and 50 mg/L)PNS groups, and liproxstatin-1 (ferroptosis inhibitor) group. The morphological changes of the cells were observed under a light microscope. Cell viabilty was detected by CCK-8 assay. Collagen type I (Col-l), solute carrier family 7 member 11(SLC7A11) and glutathione peroxidase 4(GPX4)protein expression levels were detected by Western blot. The morphological changes of mitochondria were observed by transmission electron microscopy. The Fe2+ level was detected by FerroOrange fluorescent probe. The intracellular reactive oxygen species (ROS) content was detected by DCFH-DA fluorescent probe. The content of glutathione (GSH)was determined by colorimetry. RESULTS: Compared with blank group, the majority of the cells in model group displayed long spindle shape, fibrotic appearance, unstable adhesion, and obvious morphological changes. Under electron microscope, mitochondrial double membrane density increased, and cristae decreased significantly, presenting typical ferroptosis. The expression of Col-I increased, GPX4 and SLC7A11 protein expression decreased, Fe2+ and ROS levels increased, and GSH content decreased (all/><0. 05). Compared with model group, most of the cells in low-, medium- and high-dose PNS groups were round and epit he lo id, with decreased mitochondrial membrane density, increased ridge number and normal morphology, decreased Col-I expression and ROS level, and increased GSH content (all P<0. 05). Compared with model group, the protein expression levels of GPX4 and SLC7A11 in medium- and high-dose PNS groups were significantly increased, while the content of Fe2+ was significantly decreased (all P<0. 05). There were no significant differences in cell and mitochondrial morphology and indicator levels between liproxstatin-1 group and high-dose PNS group (all 05). CONCLUSION: Panax notoginseng saponins can alleviate OSF by preventing the ferroptosis of HaCaT cells induced by ANE. [ABSTRACT FROM AUTHOR]

This paper proposes an improved Wilkinson power divider design scheme to solve the low port isolation and large insertion loss in the front-end power divider module of the multi-channel transceiver in wireless communication. Based on the principle of Wilkinson power divider, this design uses the 1/4 signal wavelength transmission line itself to increase the space between the power distribution ports, thereby reduces the insertion loss caused by additional transmission lines. And the HFSS electromagnetic field simulation tool is employed to obtain the wave-length of the signal in the transmission line. According to the proposed scheme, both 1 to 2 and 1 to 4 Wilkinson power dividers are designed. The simulation results show that this design can effectively reduce the insertion loss and improve the port isolation of the power divider. [ABSTRACT FROM AUTHOR]

A three-stage differential common source structure is used to design a W-band power amplifier based on 65-nm CMOS technology, and two way current-mode power combining structures are used for power combining to increase output power. In order to achieve single-ended to differential conversion, impedance matching, and DC power supply at the same time, the matching network adopts a transformer structure. The simulation results show that under a supply voltage of 1 V, the power amplifier has a small signal gain of 12. 7 to 15. 7 dB, a 3-dB bandwidth of 84 to 104 GHz, a saturated output power of 14. 6 dBm, and a peak power added efficiency of 9. 7%. The power amplifier has good large signal performance, and the core area of the chip is only 0. 115 mm². [ABSTRACT FROM AUTHOR]

ANU cipher, published on SCN 2016 by Bansod et al, is an ultra lightweight Feistel block cipher. There was no integral attack proposed against it yet. In order to study the resistance against integral analysis of ANU cipher, this paper established a MILP model based on bit-based division according to the structure of ANU cipher. By solving the model, it got the 9- round integral distinguisher of ANU for the first time . Based on the 9-round integral distinguisher and the correlation between round keys, it attacked 12-round ANU with 128 bit key size and could recover 43 bit round key. The data complexity of this attack is 263 5 8 chosen plaintext, the time complexity is 288 42 of 12-round encryption, and the storage complexity is 233 . [ABSTRACT FROM AUTHOR]

Objective To investigate the relationship between serum albumin (ALB) and insulin sensitivity in patients with obesity by hyperinsulinemic-euglycemic clamp. Methods One hundred and forty-four patients who underwent the hyperinsulinemic-euglycemic clamp in the Department of Endocrinology and Metabolism, the First Affiliated Hospital of Nanjing Medical University from January 2015 to December 2018 were included retrospectively. All participants were divided into 3 groups including 37 subjects with normal body mass index and normal glucose regulation (NNGR), 34 obese individuals with normal glucose regulation (ONGR) and 73 obese patients with impaired glucose regulation (OIGR). The OIGR group included 15 patients with prediabetes (1 patient with impaired fasting glucose and 14 patients with impaired glucose tolerance) as well as 58 patients with diabetes. Basic characteristics, serum albumin and other laboratory test results were recorded. Glucose infusion rate (GIR) was calculated to evaluate insulin sensitivity. Binary logistic regression analysis was used to analyze the correlation between serum albumin and insulin resistance. Receiver operating characteristic (ROC) curve was used to access the efficacy of homeostasis model assessment of insulin resistance (HOMA-IR) and 1/ALB for the evaluation of insulin resistance. Results The ALB level [(42.28±3.48), (44.04±3.12) vs. (46.33± 3.52) g/L, P<0.05] and the GIR level [(3.55±1.46), (4.77±1.60) vs. (10.38±2.97) mg · kg-1 · min-1, P< 0.05] gradually increased from OIGR group to ONGR group and NNGR group. ALB in 107 obese participants were positively correlated with GIR (r=0.352, P<0.01). ALB level was an independent factor to improve insulin resistance in obese subjects (OR=0.744, P=0.002). GIR was the standard for the ROC curve. The areas under different exponential curves were HOMA-IR+1/ALB (0.834), 1/ALB (0.757) and HOMA-IR (0.710), respectively. HOMA-IR combined with 1/ALB for the evaluation of insulin resistance corresponded to sensitivity at 64.0% and specificity at 92.5%. Conclusions Low ALB levels in obese individuals are independently correlated with insulin resistance. HOMA-IR combined with 1/ALB can better evaluate insulin resistance compared with HOMA-IR in obese subjects, with higher sensitivity and specificity. [ABSTRACT FROM AUTHOR]

Vegetation plays an important role in regulating the terrestrial carbon balance and the climate system, and also overwhelmingly dominants the provisioning of ecosystem services. However, changes occurred on small temporal scales and the persistency or robustness of the changes was often not fully understood. Documentation of changes in vegetation over the most recent years is limited. These documented changes are especially important for policy development and ecosystem conservation and recovery. In this study, with GIMMS NDVI (1982-2006) and MODIS NDVI (2000-2012) datasets in Xinjiang, the spatio-temporal patterns of changes in monthly NDVI and their linkage with change in temperature, precipitation, evapotranspiration, humidity index and human activity were analyzed from March to November at regional and pixel scales. To detect the trend of NDVI during a given period, a least -squares linear regression was applied. To further explore the climatic factors driving NDVI change, interannual correlations between NDVI and climatic variables were calculated using Pearson correlation analysis. To analyze the temporal patterns and dynamic process, we estimated trends of NDVI and the correlation between NDVI and climatic factors over progressively longer periods of 25 to 31 years since 1982 and calculated the percentage of the area that showed a positive or negative trend in the seven nested time series. The monthly NDVI was significantly increased in all months besides November, but there were two distinct periods with opposite trends in most of these months, especially in June to September, from which it increased before 1998 or 1997 or decreased after 1998 or 1997. The trend of reversal of NDVI change also led to that the rate of NDVI increase was notably slowed or stopped as the NDVI record grew in an incremental length from 1982-2006, 1982-2007, ..., to 1982-2012 for March-October. At pixel scale, the areas with significantly change of NDVI in size highly significantly (P<0.01) increased during seven periods in most months, especially for those with a significant (P<0.05) decrease trend. The rate of increase in size of areas with significant decreasing NDVI was larger than that with significant increasing NDVI in all nine months. Consequently, this caused stall or slow increase of regional scale NDVI. The response of vegetation NDVI to climate change for different months was different. The response of NDVI in March-June and September-November was more sensitive to thermal indicator, such as temperature and evapotranspiration. The correlation between NDVI and precipitation and humidity index was stronger in July-August, and areas with significant (P<0.05) correlation were larger. Moreover, the effects of spring temperature on vegetation growth were more substantial at high elevations, such as Altai Mountains, Tianshan Mountains, than that at low elevation. In addition, the impact of climate on vegetation became more significant over a longer time scale. Meanwhile, change in NDVI was significantly (P<0.05) affected by human activities. The change of planting structure and farming methods were also the driving factors. The promotion of agricultural production such as the rapid increase in the proportion of cotton cultivation and the change from flood to drip irrigation may reduce March-May NDVI in some farmland areas. The difference in study time spanning generates different results. Trend analysis during the multiple nested time series may contribute to a better and thorough understanding of NDVI dynamic. Extending the time series as much as possible and focusing on the course of change are particularly important in studies that monitor vegetation dynamics and its relationship with climate change. [ABSTRACT FROM AUTHOR]