Search

Your search keyword '"Anan, Kotaro"' showing total 2 results
Start Over Author "Anan, Kotaro" Database Academic Search Index
2 results on '"Anan, Kotaro"'

1. Distinct Roles of the NAD+-Sirt1 and FAD-LSD1 Pathways in Metabolic Response and Tissue Development.

Author

Nakao, Mitsuyoshi, Anan, Kotaro, Araki, Hirotaka, and Hino, Shinjiro

Subjects
*MUSCLE growth, *SKELETAL muscle, *INSULIN, *TISSUES, *HORMONES
Abstract

Various nutritional signals are transduced by two epigenetic pathways: NAD-dependent sirtuin Sirt1 (NAD+-Sirt1) deacetylase and flavin adenine dinucleotide–dependent lysine-specific demethylase 1 (FAD-LSD1). These pathways are controlled by dietary vitamins and nutrient-responsive hormones such as glucocorticoids and insulin, resulting in endocrine–metabolism–epigenome cooperation in adipocyte and skeletal muscle development. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

2. Lysine Demethylase LSD1 Coordinates Glycolytic and Mitochondrial Metabolism in Hepatocellular Carcinoma Cells.

Author

Sakamoto, Akihisa, Hino, Shinjiro, Nagaoka, Katsuya, Anan, Kotaro, Ryuta Takase, Haruka Matsumori, Hidenori Ojima, Yae Kanai, Kazunori Arita, and Mitsuyoshi Nakao

Subjects
*GLYCOLYSIS, *LYSINE, *PROTEINS, *CANCER cells, *PHYSIOLOGICAL adaptation
Abstract

The article focuses on glycolytic and mitochondrial metabolism in hepatocellular carcinoma cells by the protein Lysine Demethylase (LSD1). Topics discussed includes mitochondrial to glycolytic metabolism shift in cancer cells, role of LSD1 in maintaining the metabolic shift in human hepatocellular carcinoma cells and epigenetic plasticity of cancer cell metabolism.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results