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1. Pharmacokinetics of direct oral anticoagulants after bariatric surgery: A retrospective cohort study.

Author

Gunka, Barbara, Mackenzie, Danielle, Hughes, Taylor, Sardo, Laurie, Bayadinova, Julia, Siegal, Deborah M., Tseng, Eric K., Doumouras, Aristithes G., and Mithoowani, Siraj

Subjects
*BARIATRIC surgery, *ORAL medication, *PHARMACOKINETICS, *ATRIAL fibrillation, *COHORT analysis
Abstract

[Display omitted] • Obesity is a risk factor for venous thromboembolism and atrial fibrillation. • Patients frequently require oral anticoagulation after bariatric surgery. • Pharmacokinetics of oral anticoagulants may be altered after bariatric surgery. • We found that bariatric surgery may cause malabsorption of DOACs. • Patients on dabigatran or who had highly malabsorptive surgery were at highest risk. [ABSTRACT FROM AUTHOR]

Published
2024
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