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Abstract: An extension of the turbulent flame speed closure model rendering the model applicable to multiphase flow and ignition is presented. As formerly no coupling between reaction progress variable and enthalpy was existent, except through the temperature dependency of the laminar flame speed, an adaptation is proposed which offers an interface to initiate the combustion process. The modification to incorporate multiphase conditions is achieved by substituting the mixture fraction variable as representation of the composition in the original implementation of the turbulent flame speed closure model with independent species. Source terms to correlate the species progress to the reaction progress variable are derived in this work. The additional transport equations serve a higher generality of the model and enable the proper treatment of vaporizing fuel droplets. It is demonstrated that limitations which arise in the standard formulation of the model, stemming from differences in the transport equation for the reaction progress variable and the mixture fraction, are addressed and resolved by the new approach. Regarding the initiation of the flame, an additional source term for the reaction progress variable is introduced, which relates the reaction progress to the auto-ignition time. This allows the development of the flame without imposing artificial boundary conditions. The correct model behavior is established by means of a series of widely used test cases. The results of these simulations show that the model’s potential to predict flame growth and more generally the flame evolution as a function of time and space is preserved. At the same time more sophisticated test case boundary conditions involving multiphase conditions and variable inflows in terms of composition can be incorporated. As a thorough assessment of the extended model capabilities, a multiphase lab scale set-up, which provides a comprehensive data set, is presented. The good agreement of the obtained results underline the range of applicability of the extended model and its accuracy, albeit its simplicity, for multiphase conditions. [Copyright &y& Elsevier]