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Recent research has revealed links between a quasi-decadal mode of climate variability over the North Pacific – the Pacific Decadal Precession (PDP) – and the North Pacific's western boundary current's extension – the Kuroshio Extension (KE). It is suggested that on decadal time scales the PDP both responds to and influences the KE variability. A question yet to be answered is whether it is the large-scale or the mesoscale variations of the KE region that link with the PDP evolution. Using high-resolution sea surface temperature data (1981–2018) from the global ocean Operational Sea Surface Temperature (SST) and Sea Ice Analysis, low-resolution Extended Reconstructed SST (ERSST) version 3b data (1949–2018), geopotential height reanalysis data from the European Centre for Medium-Range Weather Forecasts (ECMWF) and the National Centers for Environmental Prediction (NCEP) we find that it is the large-scale variations in the KE region that correlate best with the PDP-like response in the overlying and downstream atmosphere as compared to the mesoscale variations. In particular, the second mode of the large-scale KE region, which is characterized by the warming (cooling) of the ocean south (north) of the KE, sets up a PDP-like north-south atmospheric pressure dipole over the North Pacific Ocean by altering the large-scale baroclinicity of the atmosphere and zonal intensification of the subtropical jet stream. In turn, there is a reduction in the zonal propagation of stationary wave energy and an enhancement of the climatological zonal wave heights over North America, which results in a downstream response over the North American continent and the formation of a subsequent east-west pressure dipole over the North Pacific and North American continent. As a result, there is a strong correlation between large-scale SST variations in the KE region and the evolution of the PDP over the next three years. [ABSTRACT FROM AUTHOR]

The El Niño Southern Oscillation (ENSO), as one of the largest coupled climate modes, influences the livelihoods of millions of people and ecosystems survival. Thus, how ENSO is expected to behave under the influence of anthropogenic climate change is a substantial question to investigate. In this paper, we analyze future predictions of specific traits of ENSO, in combination with a subset of well-established precursors—the Trade Wind Charging and North Pacific Meridional Mode (TWC/NPMM). We study it across three sets of experiments from a protocol-driven ensemble from CMIP6—the High Resolution Model Intercomparison Project (HighResMIP). Namely, (1) experiments at constant 1950's radiative forcings, and (2) experiments of present (1950–2014) and (3) future (2015–2050) climate with prescribed increasing radiative forcings. We first investigate the current and predicted spatial characteristics of ENSO events, by calculating area, amplitude and longitude of the Center of Heat Index (CHI). We see that TWC/NPMM-charged events are consistently stronger, in both the presence and absence of external forcings; however, as anthropogenic forcings increase, the area of all ENSO events increases. Since the TWC/NPMM-ENSO relationship has been shown to affect the oscillatory behavior of ENSO, we analyze ENSO frequency by calculating CHI-analogous indicators on the Continuous Wavelet Transform (CWT) of its signal. With this new methodology, we show that across the ensemble, ENSO oscillates at different frequencies, and its oscillatory behavior shows different degrees of stochasticity, over time and across models. However, we see no consistent indication of future trends in the oscillatory behavior of ENSO and the TWC/NPMM-ENSO relationship. [ABSTRACT FROM AUTHOR]

The El Niño Southern Oscillation (ENSO) is one of the most prominent modes of coupled variability with sizable impacts on global climate and weather patterns, which makes the ability to predict the occurrence and development of ENSO events of fundamental importance. In order to achieve accurate and timely predictions, a well-established strategy is to understand and monitor known ENSO precursors. In this paper, we focus on North Pacific Oscillation (NPO)-related precursors, namely the trade wind charging and the Northern Pacific meridional mode (TWC/NPMM). In particular, we assess whether the TWC/NPMM mode and its relationship with ENSO is reconstructed across the CMIP6 protocol-driven ensemble High Resolution Model Intercomparison Project, which was developed to systematically test the impact of increased horizontal resolution. Here, we see that the TWC/NPMM is a consistent precursor of ENSO across the ensemble, notwithstanding some spatial variations in the reconstruction. Furthermore, previous analyses on observationally-based data show that the TWC/NPMM-ENSO relationship is robust, albeit not stationary, and its variations can influence the characteristic variability of ENSO itself. In particular, during those years when the TWC/NPMM-ENSO coupling is weak, ENSO oscillates regularly with constant periodicity; whereas, when the coupling is strong, ENSO shows a more stochastic behavior. A selected subset of better-performing HighResMIP models are able to reproduce the non-stationarity of the TWC/NPMM-ENSO coupling and to recreate how these variations are reflected in the characteristics of ENSO variability, similar to what was recorded in the observational analysis. In parallel with these analyses, we also assess their sensitivity to horizontal resolution and find that there is no consistent impact of resolution on the results described above. [ABSTRACT FROM AUTHOR]

The solar wind energy input and dissipation in the magnetospheric–ionospheric systems of 17 supersubstorms (SSSs: SML < −2500 nT) triggered by interplanetary shocks during solar cycles 23 and 24 are studied in detail. The SSS events had durations ranging from ∼42 minutes to ∼6 hr, and SML intensities ranging from −2522 nT to −4143 nT. Shock compression greatly strengthens the upstream interplanetary magnetic field southward component (B s), and thus, through magnetic reconnection at the Earth's dayside magnetopause, greatly enhances the solar wind energy input into the magnetosphere and ionosphere during the SSS events studied. The additional solar wind magnetic reconnection energy input supplements the ∼1.5 hr precursor (growth-phase) energy input and both supply the necessary energy for the high-intensity, long-duration SSS events. Some of the solar wind energy is immediately deposited in the magnetosphere/ionosphere system, and some is stored in the magnetosphere/magnetotail system. During the SSS events, the major part of the solar wind input energy is dissipated into Joule heating (∼30%), with substantially less energy dissipation in auroral precipitation (∼3%) and ring current energy (∼2%). The remainder of the solar wind energy input is probably lost down the magnetotail. It is found that during the SSS events, the dayside Joule heating is comparable to that of the nightside Joule heating, giving a picture of the global energy dissipation in the magnetospheric/ionospheric system, not simply a nightside-sector substorm effect. Several cases are shown where an SSS is the only substorm that occurs during a magnetic storm, essentially equating the two phenomena for these cases. [ABSTRACT FROM AUTHOR]

The primary scientific goal of ICARUS (Investigation of Coronal AcceleRation and heating of solar wind Up to the Sun), a mother-daughter satellite mission, proposed in response to the ESA "Voyage 2050" Call, will be to determine how the magnetic field and plasma dynamics in the outer solar atmosphere give rise to the corona, the solar wind, and the entire heliosphere. Reaching this goal will be a Rosetta Stone step, with results that are broadly applicable within the fields of space plasma physics and astrophysics. Within ESA's Cosmic Vision roadmap, these science goals address Theme 2: "How does the Solar System work?" by investigating basic processes occurring "From the Sun to the edge of the Solar System". ICARUS will not only advance our understanding of the plasma environment around our Sun, but also of the numerous magnetically active stars with hot plasma coronae. ICARUS I will perform the first direct in situ measurements of electromagnetic fields, particle acceleration, wave activity, energy distribution, and flows directly in the regions in which the solar wind emerges from the coronal plasma. ICARUS I will have a perihelion altitude of 1 solar radius and will cross the region where the major energy deposition occurs. The polar orbit of ICARUS I will enable crossing the regions where both the fast and slow winds are generated. It will probe the local characteristics of the plasma and provide unique information about the physical processes involved in the creation of the solar wind. ICARUS II will observe this region using remote-sensing instruments, providing simultaneous, contextual information about regions crossed by ICARUS I and the solar atmosphere below as observed by solar telescopes. It will thus provide bridges for understanding the magnetic links between the heliosphere and the solar atmosphere. Such information is crucial to our understanding of the plasma physics and electrodynamics of the solar atmosphere. ICARUS II will also play a very important relay role, enabling the radio-link with ICARUS I. It will receive, collect, and store information transmitted from ICARUS I during its closest approach to the Sun. It will also perform preliminary data processing before transmitting it to Earth. Performing such unique in situ observations in the area where presumably hazardous solar energetic particles are energized, ICARUS will provide fundamental advances in our capabilities to monitor and forecast the space radiation environment. Therefore, the results from the ICARUS mission will be extremely crucial for future space explorations, especially for long-term crewed space missions. [ABSTRACT FROM AUTHOR]

A method is developed to determine the Hall voltage for the case of a Hall plate exposed to a piecewise constant magnetic field. The electromagnetic field is discontinuous at the interface between any two subdomains. The conditions satisfied by the electric field on a discontinuity curve (interface) inside a Hall plate with four contacts are obtained as: (a) the continuity of the potential function along the whole plate and (b) a discontinuity relationship for the flux function across the interface in terms of the potential function on the interface. An application of the method is given for the case of four point contacts where the voltage along the interface is computed using a complex variable interface element method. This voltage is used to calculate the Hall voltage of the entire plate structure. [ABSTRACT FROM AUTHOR]

A search for extremely slow (V sw < 300 km sâˆ'1) solar winds (ESSWs) at 1 au has been conducted using hourly average solar wind data from 1963 through 2021. 297 ESSW events were identified with an average duration of ∼2.0 ± 1.4 days. The lowest speed detected was 156 km sâˆ'1. Ten of the lowest-speed events were analyzed in detail. It was found that all 10 events were located at the ends of high-speed solar wind (HSSW) streams. The termination of the ESSWs was caused by high-density plasmas, either a corotating interaction region associated with the next HSSW stream or a heliospheric plasma sheet encounter. There was a greater occurrence of ESSW events in solar cycles 23 and 24 than in previous solar cycles. This phenomenon is associated with the much lower solar activity during these two cycles. The decrease in solar polar open magnetic fields was accompanied by an increase in low and midlatitude open magnetic fields. The ESSWs were accompanied by low interplanetary magnetic fields (4.4 ± 2.1 nT) and low negative interplanetary B z fields (âˆ'1.7 ± 1.5 nT), which led to extreme geomagnetic quiet: AE = 67 ± 78 nT and Dst = 2.2 ± 9.9 nT. We encourage magnetospheric researchers to use ESSW events to better understand the ground states of the magnetosphere and ionosphere. [ABSTRACT FROM AUTHOR]

Among the cross currents of social and intellectual life in the early modern era, wonder, utility, and playfulness combined to inspire curiosity and to give value to novel alchemical procedures and chemical remedies. One of the most skilful alchemical and medical performers, who brought theatrical techniques to bear upon an economy of alchemical secrets and magic, was the self-trained Paracelsian physician, mining expert, and alchemical adept, Leonhard Thurneisser zum Thurn (1531–1596). In creatively designed and illustrated books produced for a luxury market, he constructed, in words and images, theatres of procedure, instrumentation, and chemical curiosity based in traditions of Renaissance magic and Paracelsian natural philosophy. Thurneisser's books combined strategies of spectacle and performance within the context of chemical analysis, and in one text especially brought the dramatic technique of "making strange" to bear upon promoting alchemical procedures for purposes of exposing the hidden powers within plants. In staging analytical spectacles involving measurement, instrumentation, and distillation as part of the analysis of minerals, waters, and plants, Thurneisser brought together laboratory-based procedures and theoretically grounded performances within the alchemical marketplace and engaged the agency of readers in establishing the credibility of the philosophy of nature that underscored the products he produced and sold. [ABSTRACT FROM AUTHOR]

The near-Earth solar wind is in general super-Alfvénic and supermagnetosonic. Using all available near-Earth solar wind measurements between 1973 and 2020, we identified 30 intervals with sub-Alfvénic solar winds. The majority (83%) of the events occurred within interplanetary coronal mass ejection magnetic clouds (MCs)/driver gases. These MC sub-Alfvénic events are characterized by exceptionally low plasma densities (Nsw) of ∼0.04–1.20 cm−3, low temperatures (Tsw) of ∼0.08 × 105 K to 12.46 × 105 K, enhanced magnetic field intensities (B0) of ∼8.3–53.9 nT, and speeds (Vsw) of ∼328–949 km s−1. The resultant high Alfvén wave speeds (VA) ranged from ∼410 to 1471 km s−1. This is consistent with a mechanism of the MC expansions as they propagate radially outward, causing small pockets of sub-Alfvénic wind regions within the MCs. The remainder of the sub-Alfvénic intervals (17%) occurred within the extreme trailing portions of solar wind high-speed streams (HSSs). These HSS sub-Alfvénic winds had low Nsw of ∼0.04–0.97 cm−3, low Tsw of ∼0.06 × 105 K to 0.46 × 105 K, B0 of ∼6.3–18.2 nT, Vsw of ∼234–388 km s−1, and a VA range of ∼364–626 km s−1. This is consistent with a mechanism of solar wind super-radial expansions in the trailing HSS regions. During sub-Alfvénic solar wind intervals, Earth's bow shock nose exhibited rapid evanescence, and the estimated geocentric magnetopause distance increased by ∼33%–86%. The inner magnetosphere was more or less unaffected by the sub-Alfvénic solar winds. No significant impact was observed in the outer radiation belt relativistic electrons, and no geomagnetic storms or substorms were triggered during the sub-Alfvénic solar wind events. [ABSTRACT FROM AUTHOR]

To improve coke performance in the cupola, the authors discovered that coke used in blast furnaces [low coke reactivity index (CRI), high coke strength after reaction (CSR)] exhibits higher strength than foundry coke and may provide better performance due to larger coke pieces reaching the melt zone. Coke strength and sizing are extremely important in a cupola because the coke must reach the melt zone intact, stay in the melt zone long enough to replenish the coke bed, provide heat for melting and carbon pickup to the liquid iron. This research evaluates the cupola performance difference between cokes of high and low CRI. In addition, efforts were made to identify differences in characteristics of these cokes. [ABSTRACT FROM AUTHOR]

Making things by means of alchemical know-how, and the habits of knowledge used to sort, classify, and explain alchemy's made things relied upon different traditions of learning and functioned as parts of separate knowledge networks, each making claims, in distinctive ways, to epistemic authority. When alchemy crossed the threshold of the early modern university, networks, and their epistemes, intertwined; and in one instance, the case of alchemical things-in-the-making at the late sixteenth- and early seventeenth-century Kassel courts of Wilhelm IV and his son Moritz, one network affected the other as a result of a planned didactic encounter created by princely command. In the interaction, the local network of court experience at Kassel intersected with the more universal network of traditional pedagogy at the court's university in Marburg. The entanglement produced both intellectual and social disturbance as traditional ways of knowing collided with practices supported by theoretical assumptions viewed as incompatible with established didactic method and logical claims to truth. [ABSTRACT FROM AUTHOR]

Interplanetary coronal mass ejections (ICMEs), magnetic clouds (MCs), sheaths, corotating interaction regions (CIRs), solar wind high-speed streams (HSSs), fast forward shocks (FSs), reverse waves (RWs), stream interfaces, and heliospheric current sheet crossings detected upstream of the Earth and their geoeffectiveness are studied during 2017 September. The most intense geomagnetic storm (SYM-H peak = −146 nT) starting on September 7 had a three-step main phase. A compound interplanetary structure resulting from an FS encountering and compressing the upstream MC southward interplanetary magnetic fields (IMFs) caused the first two steps of the storm. A magnetospheric supersubstorm (SSS; SML peak = −3712 nT) led to the third and most intense step. An MC portion of an ICME created an intense storm (SYM-H peak = −115 nT) on September 8. A second SSS (SML peak = −2642 nT) occurred during the main phase of this storm. Intense geomagnetically induced currents (GICs) occurred during the SSSs. Two moderate magnetic storms with peak SYM-H indices of −65 and −74 nT occurring on September 13 and 27 were caused by sheath and CIR southward IMFs, respectively. Six FSs and their associated sheaths caused sudden impulses (SI+s) of magnitude ranging from +11 to +56 nT. The shocks/sheaths led to magnetospheric relativistic electron flux decreases. The RWs caused SI−s and substorm recoveries by reducing southward IMFs. The high-intensity long-duration continuous AE activities (HILDCAAs) caused by the HSSs were related to the increase/acceleration of relativistic electron fluxes. [ABSTRACT FROM AUTHOR]

This article examines whether and how sacramental liturgy and the Christian life-ethic are intrinsically related, a fundamental problematic in theory and practice in the decades since Vatican Council II. The first half of the essay examines the state of the question, starting with a brief articulation of the normative tradition based in scripture and the council's Constitution on the Sacred Liturgy, followed by a selective review of the theological discussion, centered on Don E. Saliers's virtue-ethics approach. The second half, building on a thesis of Johann Baptist Metz, argues for poverty of spirit as the key virtue for practically bonding liturgy and ethics. [ABSTRACT FROM AUTHOR]

Reports that United States (U.S.) federal agencies rely more on Web-based technologies to provide a range of information resources and services. Content of U.S. federal Web sites; Policy environment for federal Web sites; Information on the report `Security Controls for Computer Systems,' published by the U.S. Department of Defense.

Calcific aortic valve disease (CAVD) is a common cardiovascular disease that affects millions of people worldwide. The disease is characterized by the formation of calcium nodules on the aortic valve leaflets, which can lead to stenosis and heart failure if left untreated. The pathogenesis of CAVD is still not well understood, but involves several signaling pathways, including the transforming growth factor beta (TGF β ) pathway. In this study, we developed a multiscale computational model for TGF β -stimulated CAVD. The model framework comprises cellular behavior dynamics, subcellular signaling pathways, and tissue-level diffusion fields of pertinent chemical species, where information is shared among different scales. Processes such as endothelial to mesenchymal transition (EndMT), fibrosis, and calcification are incorporated. The results indicate that the majority of myofibroblasts and osteoblast-like cells ultimately die due to lack of nutrients as they become trapped in areas with higher levels of fibrosis or calcification, and they subsequently act as sources for calcium nodules, which contribute to a polydispersed nodule size distribution. Additionally, fibrosis and calcification processes occur more frequently in regions closer to the endothelial layer where the cell activity is higher. Our results provide insights into the mechanisms of CAVD and TGF β signaling and could aid in the development of novel therapeutic approaches for CAVD and other related diseases such as cancer. More broadly, this type of modeling framework can pave the way for unraveling the complexity of biological systems by incorporating several signaling pathways in subcellular models to simulate tissue remodeling in diseases involving cellular mechanobiology. [ABSTRACT FROM AUTHOR]

• Boundary value problem solution for Hall disks with an arbitrary number of asymmetric extended contacts, applicable for large magnetic fields. • The analysis method does not require the use of conformal mappings. The resistance matrix is given in terms of real-valued Cauchy integrals. • Explicit relationships are obtained for the voltages and current of the Hall structure contacts. • The solution methodology can be used with a van der Pauw method for applications. A direct analytical method for determining the Resistance Matrix of a Hall disk with an arbitrary number of extended peripheral contacts has been developed. The method does not require the use of any conformal mappings. It works also in the case of large magnetic fields. The resulting explicit formulas involve the angular coordinates of the asymmetrical contacts ends, the sheet resistance, and the Hall angle θ H as inputs. The formulas are obtained through the calculation of some definite integrals of analytical functions with integrable singularities at the end of the peripheral contacts. The method can be used for determining the sheet resistance and the Hall mobility of a circular plate with extended contacts on its boundary by utilizing two measurements similar to those used by van der Pauw's method for pointlike contacts. [ABSTRACT FROM AUTHOR]

Presents a study which described the interfaces of ion beam-deposited diamondlike carbon (DLC) films on germanium. Information on DLC films and germanium carbide; Experimental procedure; Results and discussion.

Projections of amplified climate change in the Arctic are attributed to positive feedbacks associated with the retreat of sea ice and changes in the lapse rate of the polar atmosphere. Here, a set of idealized aquaplanet experiments are performed to understand the coupling between high-latitude feedbacks, polar amplification, and the large-scale atmospheric circulation. Results are compared to CMIP5. Simulated climate responses are characterized by a wide range of polar amplification (from none to nearly 15-K warming, relative to the low latitudes) under CO2 quadrupling. Notably, the high-latitude lapse rate feedback varies in sign among the experiments. The aquaplanet simulation with the greatest polar amplification, representing a transition from perennial to ice-free conditions, exhibits a marked decrease in dry static energy flux by transient eddies. Partly compensating for the reduced poleward energy flux is a contraction of the Ferrel cell and an increase in latent energy flux. Enhanced eddy energy flux is consistent with the upper-tropospheric warming that occurs in all experiments and provides a remote influence on the polar lapse rate feedback. The main conclusions are that (i) given a large, localized change in meridional surface temperature gradient, the midlatitude circulation exhibits strong compensation between changes in dry and latent energy fluxes, and (ii) atmospheric eddies mediate the nonlinear interaction between surface albedo and lapse rate feedbacks, rendering the high-latitude lapse rate feedback less positive than it would be otherwise. Consequently, the variability of the circulation response, and particularly the partitioning of energy fluxes, offers insights into understanding the magnitude of polar amplification. [ABSTRACT FROM AUTHOR]

The impact of a high-speed solar wind stream (HSS) on the topside near-equatorial ionosphere (Arecibo: 28.17°N, L = 1.3) is investigated for the first time. Although the HSS did not lead to any significant geomagnetic storm activity, the ionosphere over Arecibo became hotter and expanded significantly in altitude as compared to a non-HSS interval. The O+/H+ transition height hT increased by ~200 km in the daytime and by ~100 km at night. At the hT, the peak ionospheric electron and ion temperatures increased by ~200-500 K during day and by ~50-70 K at night. While the O+ ion concentration exhibited an overall enhancement, deep penetration of the H+ ions below hT are observed during the day. The noontime peak electron density was ~4 times higher during the HSS event compared to the non-HSS interval. We present three possible mechanisms to explain this topside ionospheric heating. [ABSTRACT FROM AUTHOR]

Literature addressing organizational ethical behavior has focused intensely on cognitive moral development, and more recently the automatic and natural moral inclinations (i.e., moral intuitions). Research addressing theincapacityfor moral reasoning, such as psychopathy, is rarely addressed in organizational behavior (Smith & Lilienfeld, 2013; Stevens, Deuling, & Armenakis, 2011). Our first aim is to develop a construct definition for functional psychopathy that is appropriate for organizational science and theoretically consistent with the extensive previous clinical and criminal research in this field. Second, we apply two versions of a scale not previously used in business research relative to moral judgments. This scale is a self-reported measure of functional psychopathy and is useful for its relationships with ethically relevant business decisions. Further, we examine which factors emerge as having the highest relationship with ethical decision making. Third, we seek to advance the usefulness of this construct by more precisely placing psychopathy within its nomological network. With these goals in mind, a combined sample of business school seniors (N = 418) participated in three studies. Findings indicate a significant influence of psychopathy over a range of ethically relevant business decisions, as well as negative correlations with factors of the Moral Approbation (Ryan & Riordan, 2000) and the Moral Awareness (Reynolds, 2006a) scales. We conclude with directions for future research and considerations for practice. [ABSTRACT FROM PUBLISHER]

Alcohol induces many alterations in the brain that are thought to contribute to alcohol addiction. Most of the known alterations are induced in all neurons of a brain area or all neurons of a given cell type, regardless of whether they were activated during behavior. While these alterations can have important modulatory effects on behavior, they cannot explain why animals respond specifically to alcohol-paired cues as opposed to all other non-paired cues and evoke highly specific goal-directed learned responses in models of drug craving. As an alternative, we hypothesize another class of alterations that are induced only within sparsely distributed patterns of neurons, called neuronal ensembles, that are selectively activated by alcohol-specific cues during behavior and encode the long-term memories underlying these learned behaviors in animal models of alcohol addiction. Here we review recent studies and techniques used to identify the role of neuronal ensembles in animal models of different phases of the alcohol addiction cycle. This article is part of the Special Issue entitled “Alcoholism”. [ABSTRACT FROM AUTHOR]

Stream networks are branched structures wherein water and energy move between land and atmosphere, modulated by evapotranspiration and its interaction with the gravitational dissipation of potential energy as runoff. These actions vary among climates characterized by Budyko theory, yet have not been integrated with Horton scaling, the ubiquitous pattern of eco-hydrological variation among Strahler streams that populate river basins. From Budyko theory, we reveal optimum entropy coincident with high biodiversity. Basins on either side of optimum respond in opposite ways to precipitation, which we evaluated for the classic Hubbard Brook experiment in New Hampshire and for the Whitewater River basin in Kansas. We demonstrate that Horton ratios are equivalent to Lagrange multipliers used in the extremum function leading to Shannon information entropy being maximal, subject to constraints. Properties of stream networks vary with constraints and inter-annual variation in water balance that challenge vegetation to match expected resource supply throughout the network. The entropy-Horton framework informs questions of biodiversity, resilience to perturbations in water supply, changes in potential evapotranspiration, and land use changes that move ecosystems away from optimal entropy with concomitant loss of productivity and biodiversity. [ABSTRACT FROM AUTHOR]

Fusarium head blight and fusarium ear rot diseases of cereal crops are significant global problems, causing yield and grain quality losses and accumulation of harmful mycotoxins. Safety limits have been set by the European Commission for several Fusarium-produced mycotoxins; mitigating the risk of breaching these limits is of great importance to crop producers as part of an integrated approach to disease management. This review examines current knowledge regarding the role of arthropods in disease epidemiology. In the field, diseased host plants are likely to interact with arthropods that may substantially impact the disease by influencing spread or condition of the shared host. For example, disease progress by Fusarium graminearum can be doubled if wheat plants are aphid-infested. Arthropods have been implicated in disease epidemiology in several cases and the evidence ranges from observed correlations between arthropod infestation and increased disease severity and mycotoxin accumulation, to experimental evidence for arthropod infestation causing heightened pathogen prevalence in hosts. Fusarium pathogens differ in spore production and impact on host volatile chemistry, which influences their suitability for arthropod dispersal. Herbivores may allow secondary fungal infection after wounding a plant or they may alter host susceptibility by inducing changes in plant defence pathways. Post-harvest, during storage, arthropods may also interact with Fusarium pathogens, with instances of fungivory and altered behaviour by arthropods towards volatile chemicals from infected grain. Host-mediated indirect pathogen-arthropod interactions are discussed alongside a comprehensive review of evidence for direct interactions where arthropods act as vectors for inoculum. [ABSTRACT FROM AUTHOR]

While low-frequency variations in precipitation amount, occurrence counts (hereafter "occurrence"), and intensity can take place on seasonal to multidecadal time scales, it is often unclear at which time scales these precipitation variations can be ascribed to potentially predictable, climate-induced changes versus simple, stochastic (i.e., random) precipitation event evolutions. This paper seeks to isolate the dominant time scales at which potentially predictable changes in observed precipitation characteristics occur over the continental United States and analyze sources of revealed potentially predictable precipitation variations for particular regions. The results highlight that at interannual time scales (here defined as those shorter than 7 years), the potential for predicting annual precipitation amounts tends to be higher than for annual event occurrence or intensity, with interannual potential predictability highest in both relatively dry and wet locations and lowest in transition regions. By contrast, at time scales greater than 7 years the potential for predicting annual event occurrence tends to be higher than amount or intensity, with >20-yr time scale potential predictability highest in relatively wet locations and lowest in relatively dry locations. To highlight the utility of this type of analysis, two robust signals are selected for further investigation, including 1) approximately 10-yr time scale variations in potentially predictable annual amounts over the northwestern United States and 2) 20-60-yr time scale variations in potentially predictable annual event occurrence over the southwestern United States. While mechanistic drivers for these observed variations are still being investigated, concurrent and precursor climate-slate estimates in the atmosphere and ocean—principally over the Pacific sector—are provided, the monitoring of which may help realize the potential for predicting precipitation variations in these regions. [ABSTRACT FROM AUTHOR]

The article discusses several Catholic Church rules that allow interchurch participation and provision of sacraments to other Christians in the U.S. The author first relates his own experience on interchurch participation and providing sacraments. It explores the rules set by Canon 844 of the Code of the Canon Law on intercommunion. The Guidelines for the Reception of Holy Communion issued by the Bishop Conference welcomes other Christians as brothers and sisters for unification.

Summary A central effort in HIV vaccine development is to generate protective broadly neutralizing antibodies, a process dependent on T follicular helper (Tfh) cells. The feasibility of using peripheral blood counterparts of lymph node Tfh cells to assess the immune response and the influence of viral and vaccine antigens on their helper functions remain obscure. We assessed circulating HIV-specific IL-21 + CD4 + T cells and showed transcriptional and phenotypic similarities to lymphoid Tfh cells, and hence representing peripheral Tfh (pTfh) cells. pTfh cells were functionally active and B cell helper quality differed depending on antigen specificity. Furthermore, we found higher frequency of pTfh cells in peripheral blood mononuclear cell specimens from the ALVAC+AIDSVAX (RV144) HIV vaccine trial associated with protective antibody responses compared to the non-protective DNA+Ad5 vaccine trial. Together, we identify IL-21 + CD4 + T cells as pTfh cells, implicating them as key populations in the generation of vaccine-evoked antibody responses. [ABSTRACT FROM AUTHOR]

White etching cracks (WECs) have been identified as a main failure mode of wind turbine gearbox bearings (WTGBs). This study reports an investigation of the destructive sectioning of a failed low speed planetary stage WTGB and the damage found at manganese sulphide (MnS) inclusions. The bearing inner raceway was sectioned through its circumferential and axial directions in order to compare the damage around inclusions in different directions. 112 damage initiating inclusions were catalogued and their properties were investigated. WECs were found attached to MnS inclusions of lengths 3–45 µm at depths of up to 630 µm from the bearing raceway surface and at a wide range of angles of orientation. Damage at MnS inclusions included internal cracking of the inclusions, separation from the surrounding steel matrix, crack initiation and WEC initiation. Evidence has been found to support the theory that WECs are subsurface-initiated by MnS inclusions, but that butterfly cracks with wings propagating at 30–50° from parallel to the raceway surface are not necessarily the same features as MnS inclusion-initiated WECs. Shorter inclusions were found to initiate longer WECs, as were the inclusions that were closer to parallel to the raceway surface in axially sectioned samples. [ABSTRACT FROM AUTHOR]

The release of seasonal (and longer) predictions of various climatological quantities is now routine. While undoubtedly devastating to lives and livelihoods, it is unclear whether seasonal extremes in precipitation-for example, extreme dry spells leading to droughts or heavy precipitation events leading to flooding-represent a feasible target for these predictions, that is, whether they are potentially predictable or are instead inherently unpredictable more than a few days to weeks in advance. This paper assesses the potential for predicting seasonal extremes in observed precipitation as a function of region and time of year by decomposing the station-based variance into that attributable to short-memory behavior of typical meteorological events-as generated from station-specific, seasonally varying, daily time-scale stationary stochastic weather models (SSWMs)-and that attributable to longer-time-scale, potentially predictable changes in precipitation-producing processes. Findings suggest the potential for making skillful predictions of seasonal precipitation extremes over the United States is enhanced (reduced) during the cool (warm) season, particularly for heavy precipitation event accumulations. Further, this potential is accentuated along the West Coast, around the Great Lakes, and over the central plains and Ohio River valley but is diminished over the Northeast and northern Great Plains. However, findings also suggest the potential for producing seasonal (and longer) predictions of seasonal precipitation extremes is spatially and seasonally dependent. As such, this paper includes supplemental material for the potentially predictable variance of seasonal extreme dry spell lengths, heavy event accumulations, and total accumulations at 774 stations across all 365 days so readers can evaluate the potential predictability for the location, timing, and metric of most relevance to them. [ABSTRACT FROM AUTHOR]

This article consists of the text of a speech delivered by Dr. Bruce T. Downing as the closing keynote speech at the Hmong Across Borders conference at the University of Minnesota in October 2013. The speech discusses how the author became involved in Hmong Studies and how the University of Minnesota came to take on an important role in Hmong Studies research in the early 1980s. The author also discusses his involvement in early Hmong refugee resettlement efforts in the U.S. and how the landscape of Hmong Studies has changed over the past several decades. [ABSTRACT FROM AUTHOR]

Using weather station data, the parameters of a stationary stochastic weather model (SSWM) for daily precipitation over the contiguous United States are estimated. By construct, the model exactly captures the variance component of seasonal precipitation characteristics (intensity, occurrence, and total amount) arising from high-frequency variance. By comparing the variance of the lower-frequency accumulations (on the order of months) between the SSWM and the original measurements, potential predictability (PP) is estimated. Decomposing the variability into contributions from occurrence and intensity allows one to establish two contributing sources of total PP. Aggregated occurrence is found to have higher PP than either intensity or the seasonal total precipitation, and occurrence and intensity are found to interfere destructively when convolved into seasonal totals. It is recommended that efforts aimed at forecasting seasonal precipitation or attributing climate variability to particular processes should analyze occurrence and intensity separately to maximize signal-to-noise ratios. Significant geographical and seasonal variations exist in all PP components. [ABSTRACT FROM AUTHOR]

Monika Hellwig's 1982 history and theology of the sacrament of penance, Sign of Reconciliation and Conversion, is representative of the expectations that theologians and pastoral ministers had for expanded forms of the sacrament. Pope John Paul II's 1984 exhortation, "Reconciliation and Penance," produced a contrasting history to assert private confession to a priest as the church's continuous tradition. That this instruction found little traction is evident in subsequent directives combatting a "crisis" of confession and the proliferation of communal penance services. The article concludes with a theological analysis of the theoretical and practical state of the question today. [ABSTRACT FROM AUTHOR]

Systemic lupus erythematosus (SLE) is characterized by multiorgan inflammation, neuropsychiatric disorders (NPSLE), and anti-nuclear antibodies. We previously identified a subset of anti-DNA antibodies (DNRAb) cross-reactive with the N-methyl-D-aspartate receptor, present in 30% to 40% of patients, able to enhance excitatory post-synaptic potentials and trigger neuronal apoptosis. DNRAb+ mice exhibit memory impairment or altered fear response, depending on whether the antibody penetrates the hippocampus or amygdala. Here, we used 18F-fluorodeoxyglucose (FDG) microPET to plot changes in brain metabolism after regional blood-brain barrier (BBB) breach. In DNRAb+ mice, metabolism declined at the site of BBB breach in the first 2 weeks and increased over the next 2 weeks. In contrast, DNRAb− mice exhibited metabolic increases in these regions over the 4 weeks after the insult. Memory impairment was present in DNRAb+ animals with hippocampal BBB breach and altered fear conditioning in DNRAb+ mice with amygdala BBB breach. In DNRAb+ mice, we observed an inverse relationship between neuron number and regional metabolism, while a positive correlation was observed in DNRAb− mice. These findings suggest that local metabolic alterations in this model take place through different mechanisms with distinct time courses, with important implications for the interpretation of imaging data in SLE subjects. [ABSTRACT FROM AUTHOR]

Abstract: Reduced-order thermal models are necessary to enable real-time assessment of the optimum operating and control conditions to improve data center energy efficiency. A 3D computational fluid dynamics (CFD) and heat transfer model of a basic raised floor, air cooled, hot aisle/cold aisle data center configuration was developed and simulation results were used to generate snapshots for initializing compact models based on the Proper Orthogonal Decomposition (POD) and the Nonlinear Principle Component Analysis (NLPCA) methods. The specific focus of the study was to numerically investigate how the thermal trends can be affected by the long-term transient flow patterns associated with leakage and how the compact models (e.g. POD and NLPCA) can be utilized for much faster implementations and characterizations of the transient flows. Using both the POD and the NLPCA method, good agreement was achieved between the full simulation results and the compact models for predicting the dynamically developed local flow structure over a range of transient cooling air supply operating conditions. In addition, the NLPCA method was implemented to better characterize the nonlinear aspects of the CFD results. The benefits of using both the POD and NLPCA methods are discussed in relation to constructing compact models as real-time predictive tools. A systematic use of the compact models has also been proposed, to enable more robust thermal management and control of data centers. [Copyright &y& Elsevier]

Abstract: The computation time for predicting optimum thermal operating conditions in data center facilities using compact thermal modeling tools is significantly reduced compared to a three dimensional, simulation-based optimization methodology. However, applying compact models to configurations outside of the geometry and operating conditions used for model development often results in inaccurate predictions. In order to model a complicated geometry, a potential remedy is to partition the room layout into a finite number of characteristic zones to which the compact models readily apply. Here, a multiple hot aisle/cold aisle data center configuration was analyzed using CFD simulations of the entire room. The room was then partitioned into two zones and the full room simulations were used to quantify the air flow across the inter-zonal partitions. The inter-zonal conditions are then used to extend the solution results from a single zone to a multiple zone configuration. Two specific room configurations are considered where the computer room air conditioning units (CRACs) are located either at the same end or opposite ends of the cold aisle. The method is found to work well when the CRACs are located at opposite ends of the cold aisles. [Copyright &y& Elsevier]

This chapter focuses upon the relation between textual and social practices that influenced the formation of a communal approach to acquiring chemical knowledge in the early seventeenth century. It also describes the utilitarian purpose of a humanist-inspired program of chemical learning that blended practices of textual/linguistic expertise and artisanal know-how. Humanism, made pragmatic, sought to define the principles for "making things well." In the design of Andreas Libavius (ca. 1555-1616), interpretive intuitions resulting from practiced reading of ancient and medieval texts combined with a knowledge of workshop language to build consensus about chymia's tools, procedures, and materials and to define its principia artificialia. [ABSTRACT FROM AUTHOR]

Magnetic field magnitude decreases (MDs) are observed in several regions of the interplanetary medium. In this paper, we characterize MDs observed by the Ulysses spacecraft instrumentation over the solar south pole by using magnetic field data to obtain the empirical size, magnetic field MD, and frequency of occurrence distribution functions. The interaction of energetic (100 keV to 2 MeV) protons with these MDs is investigated. Charged particle and MD interactions can be described by a geometrical model allowing the calculation of the guiding center shift after each interaction. Using the distribution functions for the MD characteristics, Monte Carlo simulations are used to obtain the cross-field diffusion coefficients as a function of particle kinetic energy. It is found that the protons under consideration cross-field diffuse at a rate of up to ≈11% of the Bohm rate. The same method used in this paper can be applied to other space regions where MDs are observed, once their local features are well known. [ABSTRACT FROM AUTHOR]

Highlights: [•] An analytic and numerical solution based on the Stokes’ flow model, have been presented for analyzing the viscous damping and the spring force in perforated microstructures. [•] The models developed utilize the periodic arrangement of the perforations in determining the viscous damping and the spring force. [•] The analytical solution works in the case of small to medium area ratios of the structure and the finite element numerical solutions work in the general case. [•] The results can be used to design perforated microstructures with the lowest thermal–mechanical noise by minimizing the viscous damping through the proper choice of the number of perforation holes. [•] Results from the analysis of the viscous damping were compared to measured data for some perforated gold microstructures published in the literature. [•] The model predictions, including the frame correction, show that viscous damping by itself can explain the experimentally measured quality factors in almost all cases without the need to include any other dissipation mechanisms. [Copyright &y& Elsevier]