1. Post-COVID-19 persistent headache: A multicentric 9-months follow-up study of 905 patients.
- Author
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Garcia-Azorin, David, Layos-Romero, Almudena, Porta-Etessam, Jesús, Membrilla, Javier A, Caronna, Edoardo, Gonzalez-Martinez, Alicia, Mencia, Álvaro Sierra, Segura, Tomás, Gonzalez-García, Nuria, Díaz-de-Terán, Javier, Gallardo, Victor J, Gago-Veiga, Ana Beatriz, Ballvé, Alejandro, Trigo López, Javier, Sastre-Real, María, Llauradó, Arnau, Cornejo, Ana, de Lorenzo, Íñigo, Guerrero-Peral, Ángel, and Pozo-Rosich, Patricia
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COVID-19 pandemic , *PRIMARY headache disorders , *COVID-19 , *HEADACHE , *LONG-Term Evolution (Telecommunications) - Abstract
Background: Headache is a frequent symptoms of coronavirus disease 2019 (COVID-19). Its long-term evolution remains unknown. We aim to evaluate the long-term duration of headache in patients that presented headache during the acute phase of COVID-19. Methods: This is a post-hoc multicenter ambisective study including patients from six different third-level hospitals between 1 March and 27 April 2020. Patients completed 9 months of neurological follow-up. Results: We included 905 patients. Their median age was 51 (IQR 45–65), 66.5% were female, and 52.7% had a prior history of primary headache. The median duration of headache was 14 (6–39) days; however, the headache persisted after 3 months in 19.0% (95% CI: 16.5–21.8%) and after 9 months in 16.0% (95% confidence interval: 13.7–18.7%). Headache intensity during the acute phase was associated with a more prolonged duration of headache (Hazard ratio 0.655; 95% confidence interval: 0.582–0.737). Conclusion: The median duration of headache was 2 weeks, but in approximately a fifth of patients it became persistent and followed a chronic daily pattern. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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