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Introduction: analgesic monitoring is usually based on hemodynamic parameters. These variables are insufficient to guarantee adequate anesthesia. Nociceptive assessment during surgery is essential to improve postoperative recovery. Objective: to describe the behavior of the analgesia and nociception index (ANI) during anesthetic maintenance in pediatric patients undergoing laparoscopic surgery. Material and methods: case series of pediatric patients scheduled for laparoscopic surgery using an ANI monitor. Different variables were analyzed at 5 different moments of surgery. Results: 24 patients were included. Significant changes were observed in ANI at the beginning of surgery 58.5 ± 6.0, at the pneumoperitoneum 57.4 ± 6.4 and at emersion 70.9 ± 6.3, while the mean arterial pressure (MAP) increased at emersion 74.2 ± 5.1 and heart rate (HR) decreased at the beginning of the pneumoperitoneum 96.3 ± 8.2 and at its end. The fentanyl dose presented significant differences at the end of pneumoperitoneum 0.003 ± 0.0007 and emersion 0.002 ± 0.0007. Conclusions: There is no relationship between the hemodynamic variables and the ANI value, suggesting that this index seems more sensitive than HR and MAP to moderate nociceptive stimulation in pediatric patients undergoing laparoscopic surgery. [ABSTRACT FROM AUTHOR]