1. Le rôle du pathologiste dans le diagnostic des métastases d'origine inconnue.
- Author
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Oukabli, M., Setti, K., Elochi, R., Qamouss, O., Zoubir, Y., Chahdi, H., Rharrassi, I., and Albouzidi, A.
- Subjects
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METASTASIS , *PATHOLOGISTS , *PRECANCEROUS conditions , *PATHOLOGY , *HISTOLOGY , *IMMUNOHISTOCHEMISTRY , *ANTIGENS - Abstract
Metastases are sometimes the first revelation of cancers. In metastatic disease of unknown origin, the role of the pathologist is to affirm the malignant character of the lesion; provide histological information for possible origins; and to give histological therapeutic arguments. In most of the cases, the histological analysis based on cellular morphology is sufficient to suspect a particular origin. In case of poor differentiated carcinoma in addition to the histological analysis, the immunohistochemical study allows the detection of various specific antigens. In this review, we approach various morphological criteria and the interest of the various antibodies to confirm the origin primitive of a metastasis. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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